{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:21:42Z","timestamp":1790266902771,"version":"4.1.0"},"reference-count":77,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":731,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R56IO87652"],"award-info":[{"award-number":["R56IO87652"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32HL007185"],"award-info":[{"award-number":["T32HL007185"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.rmed.2019.105822","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T03:00:20Z","timestamp":1574218820000},"page":"105822","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"special_numbering":"C","title":["CXCL9 and CXCL10 are differentially associated with systemic organ involvement and pulmonary disease severity in sarcoidosis"],"prefix":"10.1016","volume":"161","author":[{"given":"Nicholas K.","family":"Arger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa E.","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel E.","family":"Allen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan S.","family":"Benn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prescott G.","family":"Woodruff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9541-3622","authenticated-orcid":false,"given":"Laura L.","family":"Koth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.rmed.2019.105822_bib1","first-page":"167","article-title":"Sarcoidosis: a long-term follow up study. Sarcoidosis, vasculitis, and diffuse lung diseases","volume":"17","author":"Chappell","year":"2000","journal-title":"official journal of WASOG"},{"issue":"21","key":"10.1016\/j.rmed.2019.105822_bib2","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1056\/NEJMra071714","article-title":"Sarcoidosis","volume":"357","author":"Iannuzzi","year":"2007","journal-title":"N. Engl. J. Med."},{"issue":"3","key":"10.1016\/j.rmed.2019.105822_bib3","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1183\/09031936.01.00056201","article-title":"Sarcoidosis severity and socioeconomic status","volume":"18","author":"Rabin","year":"2001","journal-title":"Eur. Respir. J."},{"issue":"2","key":"10.1016\/j.rmed.2019.105822_bib4","first-page":"149","article-title":"ATS\/ERS\/WASOG statement on sarcoidosis. American thoracic society\/European respiratory society\/world association of sarcoidosis and other granulomatous disorders. Sarcoidosis, vasculitis, and diffuse lung diseases","volume":"16","author":"Hunninghake","year":"1999","journal-title":"official journal of WASOG"},{"issue":"5","key":"10.1016\/j.rmed.2019.105822_bib5","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1097\/MCP.0000000000000080","article-title":"Morbidity and mortality in sarcoidosis","volume":"20","author":"Gerke","year":"2014","journal-title":"Curr. Opin. Pulm. Med."},{"issue":"Supplement_6","key":"10.1016\/j.rmed.2019.105822_bib6","doi-asserted-by":"crossref","DOI":"10.1513\/AnnalsATS.201707-564OT","article-title":"Disease burden and variability in sarcoidosis","volume":"14","author":"Gerke","year":"2017","journal-title":"Annals of the American Thoracic Society"},{"issue":"12","key":"10.1016\/j.rmed.2019.105822_bib7","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1001\/jama.2017.11747","article-title":"Trends and patterns of differences in chronic respiratory disease mortality among US counties","volume":"318","author":"Dwyer-Lindgren","year":"2017","journal-title":"Jama"},{"issue":"5","key":"10.1016\/j.rmed.2019.105822_bib8","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1172\/JCI111852","article-title":"Gamma interferon is spontaneously released by alveolar macrophages and lung T lymphocytes in patients with pulmonary sarcoidosis","volume":"75","author":"Robinson","year":"1985","journal-title":"J. Clin. Investig."},{"issue":"2","key":"10.1016\/j.rmed.2019.105822_bib9","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1046\/j.1365-2249.2000.01365.x","article-title":"Th1 cytokine pattern in sarcoidosis is expressed by bronchoalveolar CD4(+) and CD8(+) T cells","volume":"122","author":"Prasse","year":"2000","journal-title":"Clin. Exp. Immunol."},{"issue":"2","key":"10.1016\/j.rmed.2019.105822_bib10","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1067\/mai.2001.112273","article-title":"TH1\/TH2 and TC1\/TC2 profiles in peripheral blood and bronchoalveolar lavage fluid cells in pulmonary sarcoidosis","volume":"107","author":"Inui","year":"2001","journal-title":"J. Allergy Clin. Immunol."},{"issue":"6","key":"10.1016\/j.rmed.2019.105822_bib11","first-page":"487","article-title":"Intracellular cytokine repertoire in different T cell subsets from patients with sarcoidosis","volume":"56","author":"Mollers","year":"2001","journal-title":"Thorax"},{"issue":"1","key":"10.1016\/j.rmed.2019.105822_bib12","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1164\/ajrccm.163.1.9906071","article-title":"Analysis of intracellular cytokines in CD4+ and CD8+ lung and blood T cells in sarcoidosis","volume":"163","author":"Wahlstrom","year":"2001","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"5","key":"10.1016\/j.rmed.2019.105822_bib13","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1183\/09031936.00089910","article-title":"T-helper cell type-1 transcription factor T-bet is upregulated in pulmonary sarcoidosis","volume":"38","author":"Kriegova","year":"2011","journal-title":"Eur. Respir. J."},{"issue":"4","key":"10.1016\/j.rmed.2019.105822_bib14","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1378\/chest.130.4.982","article-title":"Different angiogenic activity in pulmonary sarcoidosis and idiopathic pulmonary fibrosis","volume":"130","author":"Antoniou","year":"2006","journal-title":"Chest"},{"issue":"6","key":"10.1016\/j.rmed.2019.105822_bib15","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1111\/j.1440-1843.2006.00933.x","article-title":"Elevated levels of interferon gamma-inducible protein-10 and epithelial neutrophil-activating peptide-78 in patients with pulmonary sarcoidosis","volume":"11","author":"Sugiyama","year":"2006","journal-title":"Respirology"},{"issue":"2","key":"10.1016\/j.rmed.2019.105822_bib16","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1365-2249.2007.03423.x","article-title":"CXCL9 and 11 in patients with pulmonary sarcoidosis: a role of alveolar macrophages","volume":"149","author":"Nishioka","year":"2007","journal-title":"Clin. Exp. Immunol."},{"issue":"2","key":"10.1016\/j.rmed.2019.105822_bib17","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.rmed.2007.09.006","article-title":"Circulating levels of both Th1 and Th2 chemokines are elevated in patients with sarcoidosis","volume":"102","author":"Nureki","year":"2008","journal-title":"Respir. Med."},{"issue":"7","key":"10.1016\/j.rmed.2019.105822_bib18","doi-asserted-by":"crossref","first-page":"3827","DOI":"10.1167\/iovs.11-9244","article-title":"Simultaneous analysis of multiple cytokines in the vitreous of patients with sarcoid uveitis","volume":"53","author":"Nagata","year":"2012","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"issue":"3","key":"10.1016\/j.rmed.2019.105822_bib19","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1167\/iovs.05-0966","article-title":"Elevated serum levels of CXCL9\/monokine induced by interferon-gamma and CXCL10\/interferon-gamma-inducible protein-10 in ocular sarcoidosis","volume":"47","author":"Takeuchi","year":"2006","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"issue":"10","key":"10.1016\/j.rmed.2019.105822_bib20","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1164\/rccm.201106-1143OC","article-title":"Sarcoidosis blood transcriptome reflects lung inflammation and overlaps with tuberculosis","volume":"184","author":"Koth","year":"2011","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.rmed.2019.105822_bib21","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/1465-9921-14-121","article-title":"Interferon-inducible chemokines reflect severity and progression in sarcoidosis","volume":"14","author":"Su","year":"2013","journal-title":"Respir. Res."},{"issue":"4","key":"10.1016\/j.rmed.2019.105822_bib22","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1183\/09031936.00039714","article-title":"Longitudinal analysis of sarcoidosis blood transcriptomic signatures and disease outcomes","volume":"44","author":"Su","year":"2014","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.rmed.2019.105822_bib23","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.rmed.2019.04.005","article-title":"Serum CXCL11 correlates with pulmonary outcomes and disease burden in sarcoidosis","volume":"152","author":"Arger","year":"2019","journal-title":"Respir. Med."},{"issue":"2","key":"10.1016\/j.rmed.2019.105822_bib24","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/icb.2010.158","article-title":"CXCR3 ligands: redundant, collaborative and antagonistic functions","volume":"89","author":"Groom","year":"2011","journal-title":"Immunol. Cell Biol."},{"issue":"2","key":"10.1016\/j.rmed.2019.105822_bib25","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1097\/00054725-199606000-00004","article-title":"Chemokines in inflammatory bowel disease mucosa: expression of RANTES, macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta, and gamma-interferon-inducible protein-10 by macrophages, lymphocytes, endothelial cells, and granulomas","volume":"2","author":"Grimm","year":"1996","journal-title":"Inflamm. Bowel Dis."},{"issue":"2","key":"10.1016\/j.rmed.2019.105822_bib26","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1183\/09031936.00070610","article-title":"Blockade of Th1 chemokine receptors ameliorates pulmonary granulomatosis in mice","volume":"38","author":"Kishi","year":"2011","journal-title":"Eur. Respir. J."},{"issue":"6","key":"10.1016\/j.rmed.2019.105822_bib27","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/j.1865-1682.2012.01370.x","article-title":"Upregulation of IL-17A, CXCL9 and CXCL10 in early-stage granulomas induced by Mycobacterium bovis in cattle","volume":"60","author":"Aranday-Cortes","year":"2013","journal-title":"Transboundary and emerging diseases"},{"issue":"3","key":"10.1016\/j.rmed.2019.105822_bib28","first-page":"253","article-title":"The CXCR3-CXCL11 signaling axis mediates macrophage recruitment and dissemination of mycobacterial infection","volume":"8","author":"Torraca","year":"2015","journal-title":"Disease models & mechanisms"},{"issue":"11","key":"10.1016\/j.rmed.2019.105822_bib29","doi-asserted-by":"crossref","first-page":"6413","DOI":"10.4049\/jimmunol.161.11.6413","article-title":"Involvement of the IP-10 chemokine in sarcoid granulomatous reactions","volume":"161","author":"Agostini","year":"1998","journal-title":"J. Immunol."},{"issue":"5","key":"10.1016\/j.rmed.2019.105822_bib30","doi-asserted-by":"crossref","first-page":"L909","DOI":"10.1152\/ajplung.00430.2005","article-title":"CXCR3 surface expression in human airway epithelial cells: cell cycle dependence and effect on cell proliferation","volume":"290","author":"Aksoy","year":"2006","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"6","key":"10.1016\/j.rmed.2019.105822_bib31","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.cytogfr.2005.04.007","article-title":"CXC chemokines in angiogenesis","volume":"16","author":"Strieter","year":"2005","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.rmed.2019.105822_bib32","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0070-2153(05)68006-4","article-title":"Chemokine receptor CXCR3: an unexpected enigma","volume":"68","author":"Liu","year":"2005","journal-title":"Curr. Top. Dev. Biol."},{"issue":"8","key":"10.1016\/j.rmed.2019.105822_bib33","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1084\/jem.193.8.975","article-title":"Donor-derived IP-10 initiates development of acute allograft rejection","volume":"193","author":"Hancock","year":"2001","journal-title":"J. Exp. Med."},{"issue":"9","key":"10.1016\/j.rmed.2019.105822_bib34","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1084\/jem.20052144","article-title":"A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development","volume":"203","author":"Burns","year":"2006","journal-title":"J. Exp. Med."},{"issue":"5","key":"10.1016\/j.rmed.2019.105822_bib35","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1172\/JCI71951","article-title":"CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis","volume":"124","author":"Zohar","year":"2014","journal-title":"J. Clin. Investig."},{"issue":"29","key":"10.1016\/j.rmed.2019.105822_bib36","doi-asserted-by":"crossref","first-page":"30219","DOI":"10.1074\/jbc.M403595200","article-title":"Intracellular domains of CXCR3 that mediate CXCL9, CXCL10, and CXCL11 function","volume":"279","author":"Colvin","year":"2004","journal-title":"J. Biol. Chem."},{"issue":"12","key":"10.1016\/j.rmed.2019.105822_bib37","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1084\/jem.187.12.2009","article-title":"Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3","volume":"187","author":"Cole","year":"1998","journal-title":"J. Exp. Med."},{"issue":"8","key":"10.1016\/j.rmed.2019.105822_bib38","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1002\/eji.200323787","article-title":"CCR3 functional responses are regulated by both CXCR3 and its ligands CXCL9, CXCL10 and CXCL11","volume":"33","author":"Xanthou","year":"2003","journal-title":"Eur. J. Immunol."},{"issue":"11","key":"10.1016\/j.rmed.2019.105822_bib39","doi-asserted-by":"crossref","first-page":"6989","DOI":"10.4049\/jimmunol.0901386","article-title":"Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses","volume":"183","author":"Wang","year":"2009","journal-title":"J. Immunol."},{"issue":"10","key":"10.1016\/j.rmed.2019.105822_bib40","doi-asserted-by":"crossref","first-page":"4511","DOI":"10.4049\/jimmunol.157.10.4511","article-title":"Genes for chemokines MuMig and Crg-2 are induced in protozoan and viral infections in response to IFN-gamma with patterns of tissue expression that suggest nonredundant roles in vivo","volume":"157","author":"Amichay","year":"1996","journal-title":"J. Immunol."},{"issue":"7272","key":"10.1016\/j.rmed.2019.105822_bib41","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1038\/nature08511","article-title":"CD8(+) T lymphocyte mobilization to virus-infected tissue requires CD4(+) T-cell help","volume":"462","author":"Nakanishi","year":"2009","journal-title":"Nature"},{"issue":"11","key":"10.1016\/j.rmed.2019.105822_bib42","doi-asserted-by":"crossref","first-page":"7087","DOI":"10.4049\/jimmunol.176.11.7087","article-title":"CXCR3 and its ligands in a murine model of obliterative bronchiolitis: regulation and function","volume":"176","author":"Medoff","year":"2006","journal-title":"J. Immunol."},{"issue":"3","key":"10.1016\/j.rmed.2019.105822_bib43","first-page":"861","article-title":"Tumor necrosis factor-alpha induces cell type and tissue-specific expression of chemoattractant cytokines in vivo","volume":"142","author":"Ohmori","year":"1993","journal-title":"Am. J. Pathol."},{"issue":"7","key":"10.1016\/j.rmed.2019.105822_bib44","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1002\/1521-4141(200207)32:7<2037::AID-IMMU2037>3.0.CO;2-I","article-title":"TNFalpha-induced macrophage chemokine secretion is more dependent on NF-kappaB expression than lipopolysaccharides-induced macrophage chemokine secretion","volume":"32","author":"Ciesielski","year":"2002","journal-title":"Eur. J. Immunol."},{"issue":"6021","key":"10.1016\/j.rmed.2019.105822_bib45","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/315672a0","article-title":"Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins","volume":"315","author":"Luster","year":"1985","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.rmed.2019.105822_bib46","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1189\/jlb.1003524","article-title":"Synergistic induction of CXCL9 and CXCL11 by Toll-like receptor ligands and interferon-gamma in fibroblasts correlates with elevated levels of CXCR3 ligands in septic arthritis synovial fluids","volume":"75","author":"Proost","year":"2004","journal-title":"J. Leukoc. Biol."},{"issue":"11","key":"10.1016\/j.rmed.2019.105822_bib47","doi-asserted-by":"crossref","first-page":"3146","DOI":"10.1002\/eji.200324136","article-title":"Microbial Toll-like receptor ligands differentially regulate CXCL10\/IP-10 expression in fibroblasts and mononuclear leukocytes in synergy with IFN-gamma and provide a mechanism for enhanced synovial chemokine levels in septic arthritis","volume":"33","author":"Proost","year":"2003","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.rmed.2019.105822_bib48","doi-asserted-by":"crossref","DOI":"10.1007\/s00408-017-0037-y","article-title":"Clinical and biological insights from the university of California san Francisco prospective and longitudinal cohort","author":"Benn","year":"2017","journal-title":"Lung"},{"issue":"3","key":"10.1016\/j.rmed.2019.105822_bib49","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1378\/chest.113.3.619","article-title":"Validation of a new dyspnea measure: the UCSD shortness of breath questionnaire","volume":"113","author":"Eakin","year":"1998","journal-title":"Chest"},{"issue":"9","key":"10.1016\/j.rmed.2019.105822_bib50","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1016\/j.rmed.2010.03.027","article-title":"Assessing dyspnea and its impact on patients with connective tissue disease-related interstitial lung disease","volume":"104","author":"Swigris","year":"2010","journal-title":"Respir. Med."},{"issue":"10","key":"10.1016\/j.rmed.2019.105822_bib51","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1016\/j.rmed.2012.06.018","article-title":"The UCSD shortness of breath questionnaire has longitudinal construct validity in idiopathic pulmonary fibrosis","volume":"106","author":"Swigris","year":"2012","journal-title":"Respir. Med."},{"key":"10.1016\/j.rmed.2019.105822_bib52","series-title":"Statistics for Biology and Health","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/978-1-4614-1353-0_2","author":"Vittinghoff","year":"2012"},{"issue":"1","key":"10.1016\/j.rmed.2019.105822_bib53","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1080\/00031305.1991.10475767","article-title":"A unified approach to mixed linear models","volume":"45","author":"McLean","year":"1991","journal-title":"Am. Stat."},{"issue":"4","key":"10.1016\/j.rmed.2019.105822_bib54","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1055\/s-0030-1262209","article-title":"Assessing pulmonary disease and response to therapy: which test?","volume":"31","author":"Keir","year":"2010","journal-title":"Semin. Respir. Crit. Care Med."},{"issue":"10 Pt 1","key":"10.1016\/j.rmed.2019.105822_bib55","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1164\/ajrccm.164.10.2104046","article-title":"Clinical characteristics of patients in a case control study of sarcoidosis","volume":"164","author":"Baughman","year":"2001","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"1","key":"10.1016\/j.rmed.2019.105822_bib56","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1093\/biomet\/69.1.239","article-title":"Partial residuals for the proportional hazards regression model","volume":"69","author":"Schoenfeld","year":"1982","journal-title":"Biometrika"},{"issue":"3","key":"10.1016\/j.rmed.2019.105822_bib57","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1177\/0049124194022003004","article-title":"Modeled variance in two-level models","volume":"22","author":"Snijders","year":"1994","journal-title":"Sociol. Methods Res."},{"issue":"4","key":"10.1016\/j.rmed.2019.105822_bib58","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1084\/jem.166.4.1084","article-title":"Biochemical characterization of a gamma interferon-inducible cytokine (IP-10)","volume":"166","author":"Luster","year":"1987","journal-title":"J. Exp. Med."},{"issue":"1","key":"10.1016\/j.rmed.2019.105822_bib59","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0006-291X(05)81398-1","article-title":"Induction of members of the IL-8\/NAP-1 gene family in human T lymphocytes is suppressed by cyclosporin A","volume":"181","author":"Zipfel","year":"1991","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.rmed.2019.105822_bib60","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1189\/jlb.71.4.669","article-title":"IFN-alpha2a induces IP-10\/CXCL10 and MIG\/CXCL9 production in monocyte-derived dendritic cells and enhances their capacity to attract and stimulate CD8+ effector T cells","volume":"71","author":"Padovan","year":"2002","journal-title":"J. Leukoc. Biol."},{"issue":"1","key":"10.1016\/j.rmed.2019.105822_bib61","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1164\/ajrccm\/143.1.53","article-title":"Increased levels of serum interferon-gamma in pulmonary sarcoidosis and relationship with response to corticosteroid therapy","volume":"143","author":"Prior","year":"1991","journal-title":"Am. Rev. Respir. Dis."},{"issue":"4","key":"10.1016\/j.rmed.2019.105822_bib62","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1067\/mai.2001.113524","article-title":"Expression of IFN-gamma-inducible protein; monocyte chemotactic proteins 1, 3, and 4; and eotaxin in TH1- and TH2-mediated lung diseases","volume":"107","author":"Miotto","year":"2001","journal-title":"J. Allergy Clin. Immunol."},{"issue":"5","key":"10.1016\/j.rmed.2019.105822_bib63","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1159\/000245332","article-title":"Angiogenic and angiostatic chemokines in idiopathic pulmonary fibrosis and granulomatous lung disease","volume":"80","author":"Cui","year":"2010","journal-title":"Respiration; international review of thoracic diseases"},{"issue":"3","key":"10.1016\/j.rmed.2019.105822_bib64","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.1365-2249.2008.03832.x","article-title":"Protein levels of CC chemokine ligand (CCL)15, CCL16 and macrophage stimulating protein in patients with sarcoidosis","volume":"155","author":"Arakelyan","year":"2009","journal-title":"Clin. Exp. Immunol."},{"issue":"7\u20138","key":"10.1016\/j.rmed.2019.105822_bib65","doi-asserted-by":"crossref","first-page":"395","DOI":"10.20452\/pamw.2349","article-title":"Chemokine receptor CXCR3 ligands in bronchoalveolar lavage fluid: associations with radiological pattern, clinical course, and prognosis in sarcoidosis","volume":"124","author":"Piotrowski","year":"2014","journal-title":"Polskie Arch. Med. Wewn."},{"key":"10.1016\/j.rmed.2019.105822_bib66","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.gene.2016.09.037","article-title":"Bioinformatics analysis of gene expression profile data to screen key genes involved in pulmonary sarcoidosis","volume":"596","author":"Li","year":"2017","journal-title":"Gene"},{"issue":"3","key":"10.1016\/j.rmed.2019.105822_bib67","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1164\/rccm.200502-244OC","article-title":"Role of the chemokine receptors CXCR3 and CCR4 in human pulmonary fibrosis","volume":"173","author":"Pignatti","year":"2006","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"3","key":"10.1016\/j.rmed.2019.105822_bib68","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1183\/09031936.00157508","article-title":"CXCR3 ligands are augmented during the pathogenesis of pulmonary sarcoidosis","volume":"34","author":"Busuttil","year":"2009","journal-title":"Eur. Respir. J."},{"issue":"5","key":"10.1016\/j.rmed.2019.105822_bib69","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1165\/rcmb.2015-0278OC","article-title":"Functional toll-like receptor 9 expression and CXCR3 ligand release in pulmonary sarcoidosis","volume":"55","author":"Schnerch","year":"2016","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"1","key":"10.1016\/j.rmed.2019.105822_bib70","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.jmoldx.2014.08.005","article-title":"Diagnostic performance of a cytokine and IFN-gamma-induced chemokine mRNA assay after Mycobacterium tuberculosis-specific antigen stimulation in whole blood from infected individuals","volume":"17","author":"Kim","year":"2015","journal-title":"J. Mol. Diagn. : J. Mod. Dyn."},{"issue":"2","key":"10.1016\/j.rmed.2019.105822_bib71","doi-asserted-by":"crossref","first-page":"191","DOI":"10.5588\/ijtld.14.0525","article-title":"CXCR3 ligands as clinical markers for pulmonary tuberculosis","volume":"19","author":"Lee","year":"2015","journal-title":"Int. J. Tuberc. Lung Dis. : the official journal of the International Union against Tuberculosis and Lung Disease"},{"issue":"12","key":"10.1016\/j.rmed.2019.105822_bib72","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.5588\/ijtld.15.0325","article-title":"Serum CXCR3 ligands as biomarkers for the diagnosis and treatment monitoring of tuberculosis","volume":"19","author":"Chung","year":"2015","journal-title":"Int. J. Tuberc. Lung Dis. : the official journal of the International Union against Tuberculosis and Lung Disease"},{"issue":"3","key":"10.1016\/j.rmed.2019.105822_bib73","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.cytogfr.2014.11.009","article-title":"CXCR3 ligands in disease and therapy","volume":"26","author":"Van Raemdonck","year":"2015","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.rmed.2019.105822_bib74","series-title":"Proceedings of the National Academy of Sciences of the United States of America","first-page":"5238","article-title":"A macrophage mRNA selectively induced by gamma-interferon encodes a member of the platelet factor 4 family of cytokines","volume":"vol. 87","author":"Farber","year":"1990"},{"issue":"9","key":"10.1016\/j.rmed.2019.105822_bib75","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1038\/labinvest.3700453","article-title":"TLR ligands and cytokines induce CXCR3 ligands in endothelial cells: enhanced CXCL9 in autoimmune arthritis","volume":"86","author":"Loos","year":"2006","journal-title":"Laboratory investigation; a journal of technical methods and pathology"},{"issue":"10","key":"10.1016\/j.rmed.2019.105822_bib76","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1513\/AnnalsATS.201503-172OT","article-title":"Rationale and design of the genomic research in alpha-1 antitrypsin deficiency and sarcoidosis (GRADS) study. Sarcoidosis protocol","volume":"12","author":"Moller","year":"2015","journal-title":"Annals of the American Thoracic Society"},{"issue":"3","key":"10.1016\/j.rmed.2019.105822_bib77","first-page":"204","article-title":"Two year prognosis of sarcoidosis: the ACCESS experience. Sarcoidosis, vasculitis, and diffuse lung diseases","volume":"20","author":"Judson","year":"2003","journal-title":"official journal of WASOG"}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611119303361?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611119303361?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T11:56:58Z","timestamp":1760615818000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611119303361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":77,"alternative-id":["S0954611119303361"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2019.105822","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CXCL9 and CXCL10 are differentially associated with systemic organ involvement and pulmonary disease severity in sarcoidosis","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2019.105822","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"105822"}}