{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:04:33Z","timestamp":1747170273852,"version":"3.40.5"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"vor","delay-in-days":731,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.rmed.2022.106935","type":"journal-article","created":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T06:19:44Z","timestamp":1658211584000},"page":"106935","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Development and validation of a noninvasive prediction model for identifying eosinophilic asthma"],"prefix":"10.1016","volume":"201","author":[{"given":"Min","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi","family":"Wen Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su","family":"Jun Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian G.","family":"Oliver","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Ping Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa M.","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter G.","family":"Gibson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Ming Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Min Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Jing Wan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5048-6606","authenticated-orcid":false,"given":"Gang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.rmed.2022.106935_bib1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/pcmedi\/pbab028","article-title":"Management of severe asthma: from stepwise approach to therapy to treatable traits?","volume":"4","author":"Wang","year":"2021","journal-title":"Precis Clin Med"},{"issue":"1","key":"10.1016\/j.rmed.2022.106935_bib2","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1440-1843.2006.00784.x","article-title":"Inflammatory subtypes in asthma: assessment and identification using induced sputum","volume":"11","author":"Simpson","year":"2006","journal-title":"Respirology"},{"key":"10.1016\/j.rmed.2022.106935_bib3","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1136\/thx.2006.073429","article-title":"Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma","volume":"62","author":"Berry","year":"2007","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2022.106935_bib4","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S0140-6736(12)60988-X","article-title":"Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial","volume":"380","author":"Pavord","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.rmed.2022.106935_bib5","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1136\/thx.2010.135574","article-title":"A systematic review and meta-analysis: tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils)","volume":"67","author":"Petsky","year":"2012","journal-title":"Thorax"},{"issue":"1","key":"10.1016\/j.rmed.2022.106935_bib6","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00588-2019","article-title":"Management of severe asthma: a European respiratory society\/American thoracic society guideline","volume":"55","author":"Holguin","year":"2020","journal-title":"Eur. Respir. J."},{"issue":"6","key":"10.1016\/j.rmed.2022.106935_bib7","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/j.jaci.2020.10.003","volume":"146","year":"2020","journal-title":"J. Allergy Clin. Immunol."},{"issue":"4","key":"10.1016\/j.rmed.2022.106935_bib8","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/S2213-2600(15)00050-8","article-title":"Diagnostic accuracy of minimally invasive markers for detection of airway eosinophilia in asthma: a systematic review and meta-analysis","volume":"3","author":"Korevaar","year":"2015","journal-title":"Lancet Respir. Med."},{"key":"10.1016\/j.rmed.2022.106935_bib9","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.21037\/jtd.2017.04.74","article-title":"Severe and uncontrolled asthma in China: a crosssectional survey from the Australasian severe asthma network","volume":"9","author":"Wang","year":"2017","journal-title":"J. Thorac. Dis."},{"key":"10.1016\/j.rmed.2022.106935_bib10","article-title":"Calculating the sample size required for developing a clinical prediction model","volume":"368","author":"Riley","year":"2020","journal-title":"BMJ"},{"key":"10.1016\/j.rmed.2022.106935_bib11","unstructured":"Global strategy for asthma management and prevention 2021. Available at: https:\/\/ginasthma.org\/wp-content\/uploads\/2021\/05\/GINA-Main-Report-2021-V2-WMS.pdf."},{"issue":"1","key":"10.1016\/j.rmed.2022.106935_bib12","doi-asserted-by":"crossref","first-page":"55","DOI":"10.7326\/M14-0698","article-title":"Transparent reporting of a multivariable predictive model for individual prognosis or diagnosis (TRIPOD): the TRIPOD statement","volume":"162","author":"Moons","year":"2015","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.rmed.2022.106935_bib13","first-page":"17","article-title":"Application and assessment of hospital anxiety and depression scale in general hospital","volume":"2","author":"Ye","year":"1993","journal-title":"Chin J Behavioral Med Sci"},{"key":"10.1016\/j.rmed.2022.106935_bib14","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.jaci.2012.08.023","article-title":"The asthma control test and asthma control questionnaire for assessing asthma control: systematic review and meta-analysis","volume":"131","author":"Jia","year":"2013","journal-title":"J. Allergy Clin. Immunol."},{"issue":"12","key":"10.1016\/j.rmed.2022.106935_bib15","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1097\/00029330-200706020-00002","article-title":"Validity of asthma control test in Chinese patients","volume":"120","author":"Zhou","year":"2007","journal-title":"Chin. Med. J."},{"key":"10.1016\/j.rmed.2022.106935_bib16","first-page":"760","article-title":"The use of Juniper's asthma quality of life questionnaire in Chinese asthmatics","volume":"42","author":"Xu","year":"2003","journal-title":"Zhonghua Nei Ke Za Zhi"},{"key":"10.1016\/j.rmed.2022.106935_bib17","article-title":"Survival prediction in mesothelioma using a scalable Lasso regression model: instructions for use and initial performance using clinical predictors","volume":"5","author":"Kidd","year":"2018","journal-title":"BMJ Open Respir Res"},{"issue":"11","key":"10.1016\/j.rmed.2022.106935_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0225253","article-title":"Visualising statistical models using dynamic nomograms","volume":"14","author":"Jalali","year":"2019","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.rmed.2022.106935_bib19","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/S0895-4356(01)00341-9","article-title":"Internal validation of predictive models: efficiency of some procedures for logistic regression analysis","volume":"54","author":"Steyerberg","year":"2001","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.rmed.2022.106935_bib20","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1002\/sim.1802","article-title":"Overall C as a measure of discrimination in survival analysis:model specific population value and confidence interval estimation","volume":"23","author":"Pencina","year":"2004","journal-title":"Stat. Med."},{"key":"10.1016\/j.rmed.2022.106935_bib21","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1097\/01.CCM.0000275267.64078.B0","article-title":"Assessing the calibration of mortality benchmarks in critical care: the Hosmer-Lemeshow test revisited","volume":"35","author":"Kramer","year":"2007","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.rmed.2022.106935_bib22","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1177\/0272989X06295361","article-title":"Decision curve analysis: a novel method for evaluating predictive modes","volume":"26","author":"Vickers","year":"2006","journal-title":"Med. Decis. Making"},{"issue":"4","key":"10.1016\/j.rmed.2022.106935_bib23","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/bimj.200410135","article-title":"Estimation of the Youden Index and its associated cutoff point","volume":"47","author":"Fluss","year":"2005","journal-title":"Biom. J."},{"issue":"6","key":"10.1016\/j.rmed.2022.106935_bib24","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1081\/JAS-120004921","article-title":"Airway inflammation in premenstrual asthma","volume":"39","author":"Oguzulgen","year":"2002","journal-title":"J. Asthma"},{"key":"10.1016\/j.rmed.2022.106935_bib25","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1111\/j.1365-2222.2005.02362.x","article-title":"Female mice are more susceptible to the development of allergic airway inflammation than male mice","volume":"35","author":"Melgert","year":"2005","journal-title":"Clin. Exp. Allergy"},{"issue":"6","key":"10.1016\/j.rmed.2022.106935_bib26","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1046\/j.1365-3083.2003.01269.x","article-title":"Less sensitivity for late airway inflammation in males than females in balb\/c mice","volume":"57","author":"Hayashi","year":"2003","journal-title":"Scand. J. Immunol."},{"issue":"5","key":"10.1016\/j.rmed.2022.106935_bib27","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1111\/resp.12078","article-title":"Gender difference in allergic airway remodelling and immunoglobulin production in mouse model of asthma","volume":"18","author":"Takeda","year":"2013","journal-title":"Respirology"},{"issue":"2","key":"10.1016\/j.rmed.2022.106935_bib28","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1159\/000312635","article-title":"Airway inflammation and remodeling in two mouse models of asthma: comparison of males and females","volume":"153","author":"Blacqui\u00e8re","year":"2010","journal-title":"Int. Arch. Allergy Immunol."},{"issue":"3","key":"10.1016\/j.rmed.2022.106935_bib29","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s11882-017-0686-1","article-title":"Mechanisms driving gender differences in asthma","volume":"17","author":"Fuseini","year":"2017","journal-title":"Curr. Allergy Asthma Rep."},{"issue":"3","key":"10.1016\/j.rmed.2022.106935_bib30","first-page":"199","article-title":"Dehydroepiandrosterone attenuates allergic airway inflammation in dermatophagoides farinae-sensitized mice","volume":"35","author":"Yu","year":"2002","journal-title":"J. Microbiol. Immunol. Infect."},{"key":"10.1016\/j.rmed.2022.106935_bib31","first-page":"1e12","article-title":"Epos 2012: European position paper on rhinosinusitis and nasal polyps 2012: a summary for otorhinolaryngologists","volume":"50","author":"Fokkens","year":"2012","journal-title":"Rhinology"},{"key":"10.1016\/j.rmed.2022.106935_bib32","doi-asserted-by":"crossref","DOI":"10.1183\/23120541.00100-2015","article-title":"Clinical profile of patients with adult-onset eosinophilic asthma","volume":"2","author":"de Groot","year":"2016","journal-title":"ERJ Open Res"},{"key":"10.1016\/j.rmed.2022.106935_bib33","doi-asserted-by":"crossref","first-page":"1125e1132","DOI":"10.1164\/rccm.201103-0396OC","article-title":"Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study","volume":"184","author":"Castro","year":"2011","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.rmed.2022.106935_bib34","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/j.jaci.2006.05.031","article-title":"Nasal IL-5 levels determine the response to anti-IL-5 treatment in patients with nasal polyps","volume":"3","author":"Gevaert","year":"2006","journal-title":"J. Allergy Clin. Immunol."},{"issue":"6","key":"10.1016\/j.rmed.2022.106935_bib35","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/j.jaci.2015.10.010","article-title":"Current and future treatment options for adult chronic rhinosinusitis: focus on nasal polyposis","volume":"136","author":"Bachert","year":"2015","journal-title":"J. Allergy Clin. Immunol."},{"issue":"1_suppl","key":"10.1016\/j.rmed.2022.106935_bib36","first-page":"S1","article-title":"Targeted molecular therapies in allergy and rhinology","volume":"164","author":"Damask","year":"2021","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"10.1016\/j.rmed.2022.106935_bib37","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1146\/annurev.me.44.020193.000505","article-title":"The biology of the eosinophilic leukocyte","volume":"44","author":"Gleich","year":"1993","journal-title":"Annu. Rev. Med."},{"issue":"9","key":"10.1016\/j.rmed.2022.106935_bib38","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1111\/cea.12345","article-title":"Full blood count parameters for the detection of asthma inflammatory phenotypes","volume":"44","author":"Zhang","year":"2014","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.rmed.2022.106935_bib39","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1471-2466-13-11","article-title":"Distribution of sputum cellular phenotype in a large asthma cohort: predicting factors for eosinophilic vs neutrophilic inflammation","volume":"13","author":"Schleich","year":"2013","journal-title":"BMC Pulm. Med."},{"issue":"3","key":"10.1016\/j.rmed.2022.106935_bib40","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1111\/all.12101","article-title":"Blood eosinophil counts rarely reflect airway eosinophilia in children with severe asthma","volume":"68","author":"Ullmann","year":"2013","journal-title":"Allergy"},{"issue":"2","key":"10.1016\/j.rmed.2022.106935_bib41","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1136\/thx.53.2.91","article-title":"Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma","volume":"53","author":"Jatakanon","year":"1998","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2022.106935_bib42","series-title":"Applied Logistic Regression","first-page":"160","author":"Hosmer","year":"2000"},{"issue":"2","key":"10.1016\/j.rmed.2022.106935_bib43","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/all.12072","article-title":"Basophils are recruited to inflamed lungs and exacerbate memory Th2 responses in mice and humans","volume":"68","author":"Wakahara","year":"2013","journal-title":"Allergy"},{"issue":"31","key":"10.1016\/j.rmed.2022.106935_bib44","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.1601914113","article-title":"Alternative splicing of interleukin-33 and type 2 inflammation in asthma","volume":"113","author":"Gordon","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"10","key":"10.1016\/j.rmed.2022.106935_bib45","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1111\/all.13197","article-title":"Airway basophils are increased an activated in eosinophilic asthma","volume":"72","author":"Suzuki","year":"2017","journal-title":"Allergy"},{"issue":"10","key":"10.1016\/j.rmed.2022.106935_bib46","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1111\/all.13185","article-title":"Sputum basophils are increased in eosinophilic asthma compared with non-eosinophilic asthma phenotypes","volume":"72","author":"Brooks","year":"2017","journal-title":"Allergy"},{"issue":"5","key":"10.1016\/j.rmed.2022.106935_bib47","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1111\/all.12375","article-title":"Omalizumab therapy is associated with reduced circulating basophil populations in asthmatic children","volume":"69","author":"Hill","year":"2014","journal-title":"Allergy"},{"issue":"suppl 58","key":"10.1016\/j.rmed.2022.106935_bib48","first-page":"P2053","article-title":"Biomarkers for sputum eosinophilia in mild-moderate and severe adult-onset asthma patients","volume":"44","author":"Westerhof","year":"2014","journal-title":"Eur. Respir. J."},{"issue":"1","key":"10.1016\/j.rmed.2022.106935_bib49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1189\/jlb.0607344","article-title":"Roles of integrin activation in eosinophil function and the eosinophilic inflammation of asthma","volume":"83","author":"Barthel","year":"2008","journal-title":"J. Leukoc. Biol."},{"issue":"6","key":"10.1016\/j.rmed.2022.106935_bib50","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/j.jaci.2007.03.048","article-title":"Eosinophil trafficking in allergy and asthma","volume":"119","author":"Rosenberg","year":"2007","journal-title":"J. Allergy Clin. Immunol."},{"issue":"4","key":"10.1016\/j.rmed.2022.106935_bib51","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1111\/cea.12292","article-title":"Activation states of blood eosinophils in asthma","volume":"44","author":"Johansson","year":"2014","journal-title":"Clin. Exp. Allergy"},{"issue":"9","key":"10.1016\/j.rmed.2022.106935_bib52","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1111\/all.12445","article-title":"Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma","volume":"69","author":"Kupczyk","year":"2014","journal-title":"Allergy"},{"issue":"2","key":"10.1016\/j.rmed.2022.106935_bib53","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1136\/thoraxjnl-2014-205634","article-title":"External validation of blood eosinophils, FE(NO) and serum periostin as surrogates for sputum eosinophils in asthma","volume":"70","author":"Wagener","year":"2015","journal-title":"Thorax"}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611122002001?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611122002001?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T02:03:47Z","timestamp":1725156227000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611122002001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":53,"alternative-id":["S0954611122002001"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2022.106935","relation":{},"ISSN":["0954-6111"],"issn-type":[{"type":"print","value":"0954-6111"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development and validation of a noninvasive prediction model for identifying eosinophilic asthma","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2022.106935","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"106935"}}