{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T01:17:40Z","timestamp":1783041460124,"version":"3.54.6"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007560","name":"Chiesi Pharmaceuticals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007560","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.rmed.2026.108952","type":"journal-article","created":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T23:10:11Z","timestamp":1780787411000},"page":"108952","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Peak inspiratory flow in Austrian patients with asthma and\/or COPD using dry powder inhalers\u2013 a cross-sectional, observational real-world study"],"prefix":"10.1016","volume":"260","author":[{"given":"Marcel","family":"Rowhani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"H\u00f6rmannstorfer-Fessl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Kastner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossella","family":"Angotti-Arthofer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Falko","family":"Tiefenbacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1676-9095","authenticated-orcid":false,"given":"Lisa","family":"Liendl-Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rmed.2026.108952_bib1","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1007\/s12325-019-01066-6","article-title":"Understanding dry powder inhalers: key technical and patient preference attributes","volume":"36","author":"Levy","year":"2019","journal-title":"Adv. Ther."},{"key":"10.1016\/j.rmed.2026.108952_bib2","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1513\/AnnalsATS.201611-903OC","article-title":"Suboptimal inspiratory flow rates are associated with chronic obstructive pulmonary disease and all-cause readmissions","volume":"14","author":"Loh","year":"2017","journal-title":"Ann. Am. Thorac. Soc."},{"key":"10.1016\/j.rmed.2026.108952_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.rmed.2019.105857","article-title":"The role of inspiratory flow in selection and use of inhaled therapy for patients with chronic obstructive pulmonary disease","volume":"161","author":"Mahler","year":"2020","journal-title":"Respir. Med."},{"key":"10.1016\/j.rmed.2026.108952_bib4","doi-asserted-by":"crossref","DOI":"10.1038\/s41533-022-00282-y","article-title":"Factors associated with health status and exacerbations in COPD maintenance therapy with dry powder inhalers","volume":"32","author":"Kocks","year":"2022","journal-title":"npj Primary Care Respir. Med."},{"key":"10.1016\/j.rmed.2026.108952_bib5","doi-asserted-by":"crossref","DOI":"10.4081\/mrm.2017.236","article-title":"Recent advances in capsule-based dry powder inhaler technology","volume":"12","author":"Lavorini","year":"2017","journal-title":"Multidiscip. Respir. Med."},{"key":"10.1016\/j.rmed.2026.108952_bib7","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.chest.2023.11.011","article-title":"Consideration and assessment of patient factors when selecting an inhaled delivery system in COPD","volume":"165","author":"Mahler","year":"2024","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2026.108952_bib8","article-title":"Suboptimal peak inspiratory flow rate: a noticeable risk factor for inhaler concordance in patients with chronic airway diseases","volume":"11","author":"Meng","year":"2024","journal-title":"BMJ Open Respir. Res."},{"key":"10.1016\/j.rmed.2026.108952_bib9","article-title":"Clinical burden of chronic obstructive pulmonary disease in patients with suboptimal peak inspiratory flow","volume":"2024","author":"Ohar","year":"2024","journal-title":"Cancer Res. J."},{"key":"10.1016\/j.rmed.2026.108952_bib10","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.2147\/COPD.S380736","article-title":"Suboptimal peak inspiratory flow and critical inhalation errors are associated with higher COPD-related healthcare costs","volume":"17","author":"Leving","year":"2022","journal-title":"Int. J. Chronic Obstr. Pulm. Dis."},{"key":"10.1016\/j.rmed.2026.108952_bib11","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.2147\/COPD.S355772","article-title":"Low peak inspiratory flow rates are common among COPD inpatients and are associated with increased healthcare resource utilization: a retrospective cohort study","volume":"17","author":"Clark","year":"2022","journal-title":"Int. J. Chronic Obstr. Pulm. Dis."},{"key":"10.1016\/j.rmed.2026.108952_bib12","article-title":"Inappropriate peak inspiratory flow rate with dry powder inhaler in chronic obstructive pulmonary disease","volume":"10","author":"Chen","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.rmed.2026.108952_bib13","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1164\/rccm.200410-1414OC","article-title":"Regional lung deposition and bronchodilator response as a function of beta2-agonist particle size","volume":"172","author":"Usmani","year":"2005","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"14","key":"10.1016\/j.rmed.2026.108952_bib14","first-page":"1","article-title":"Clinical characteristics of chronic obstructive pulmonary disease patients with superoptimal peak inspiratory flow rate","volume":"141","author":"Kim","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.rmed.2026.108952_bib15","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jaci.2003.09.008","article-title":"Development of the asthma control test: a survey for assessing asthma control","volume":"113","author":"Nathan","year":"2004","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.rmed.2026.108952_bib16","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1183\/09031936.00102509","article-title":"Development and first validation of the COPD assessment test","volume":"34","author":"Jones","year":"2009","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.rmed.2026.108952_bib17","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1089\/jamp.2015.1212","article-title":"Validation of the \u2018Test of the Adherence to Inhalers\u2019 (TAI) for asthma and COPD patients","volume":"29","author":"Plaza","year":"2016","journal-title":"J. Aerosol Med. Pulm. Drug Deliv."},{"key":"10.1016\/j.rmed.2026.108952_bib18","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/1495867","article-title":"Guiding inspiratory flow: development of the In-Check DIAL G16, a tool for improving inhaler technique","volume":"2017","author":"Sanders","year":"2017","journal-title":"Pulm. Med."},{"key":"10.1016\/j.rmed.2026.108952_bib19","article-title":"Suboptimal peak inspiratory flow rate: a noticeable risk factor for inhaler concordance in patients with chronic airway diseases","volume":"11","author":"Meng","year":"2024","journal-title":"BMJ Open Respir. Res."},{"key":"10.1016\/j.rmed.2026.108952_bib20","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00239-2023","article-title":"Global initiative for chronic obstructive lung disease 2023 report: GOLD executive summary","volume":"61","author":"Agust\u00ed","year":"2023","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.rmed.2026.108952_bib21","doi-asserted-by":"crossref","first-page":"79","DOI":"10.2147\/COPD.S319511","article-title":"Measuring peak inspiratory flow in patients with chronic obstructive pulmonary disease","volume":"17","author":"Ohar","year":"2022","journal-title":"Int. J. Chronic Obstr. Pulm. Dis."},{"key":"10.1016\/j.rmed.2026.108952_bib22","article-title":"Prevalence and factors affecting the optimal and non-optimal peak inspiratory flow rate in stable and exacerbation phases of chronic obstructive pulmonary disease and bronchial asthma in India","volume":"16","author":"Murugaiya","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.rmed.2026.108952_bib23","doi-asserted-by":"crossref","first-page":"585","DOI":"10.2147\/COPD.S195438","article-title":"Prevalence and factors associated with suboptimal peak inspiratory flow rates in COPD","volume":"14","author":"Ghosh","year":"2019","journal-title":"Int. J. Chronic Obstr. Pulm. Dis."},{"key":"10.1016\/j.rmed.2026.108952_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.chest.2024.09.031","article-title":"Peak inspiratory flow and inhaler prescription strategies in a specialized COPD clinical program: a real-world observational study","author":"Pankovitch","year":"2025","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2026.108952_bib25","unstructured":"2024 GOLD Report - Global Initiative for Chronic Obstructive Lung Disease - GOLD, (n.d.). https:\/\/goldcopd.org\/2024-gold-report\/(accessed April 7, 2026)."},{"key":"10.1016\/j.rmed.2026.108952_bib26","doi-asserted-by":"crossref","first-page":"458","DOI":"10.3390\/biomedicines10020458","article-title":"Relationship between peak inspiratory flow and patient and disease characteristics in individuals with COPD\u2014A systematic scoping review","volume":"10","author":"Leving","year":"2022","journal-title":"Biomedicines"},{"key":"10.1016\/j.rmed.2026.108952_bib27","article-title":"Peak inspiratory flow in children and adolescents with asthma using dry powder inhalers: a cross-sectional study","volume":"47","author":"da Silva","year":"2021","journal-title":"J. Bras. Pneumol."},{"key":"10.1016\/j.rmed.2026.108952_bib28","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.chest.2021.03.049","article-title":"Peak inspiratory flow as a predictive therapeutic biomarker in COPD","volume":"160","author":"Mahler","year":"2021","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2026.108952_bib29","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s40261-023-01330-2","article-title":"Demystifying dry powder inhaler resistance with relevance to optimal patient care","volume":"44","author":"Capstick","year":"2024","journal-title":"Clin. Drug Invest."},{"issue":"10","key":"10.1016\/j.rmed.2026.108952_bib30","first-page":"1","article-title":"Inappropriate peak inspiratory flow rate with dry powder inhaler in chronic obstructive pulmonary disease","volume":"101","author":"Chen","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.rmed.2026.108952_bib31","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.ijpharm.2017.09.057","article-title":"Experimental and computational study of the effect of breath-actuated mechanism built in the NEXThaler\u00ae dry powder inhaler","volume":"533","author":"Farkas","year":"2017","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.rmed.2026.108952_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.rmed.2024.107916","article-title":"Particularities of deposition of two ICS-LABA fixed dose combination dry powder aerosol drugs in the airways of COPD patients","volume":"236","author":"Horv\u00e1th","year":"2025","journal-title":"Respir. Med."}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611126003203?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611126003203?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:38:26Z","timestamp":1783039106000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611126003203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":31,"alternative-id":["S0954611126003203"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2026.108952","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Peak inspiratory flow in Austrian patients with asthma and\/or COPD using dry powder inhalers\u2013 a cross-sectional, observational real-world study","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2026.108952","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"108952"}}