{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T16:35:49Z","timestamp":1793378149838,"version":"4.5.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.rmed.2026.109043","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T23:06:00Z","timestamp":1784934360000},"page":"109043","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Hepatic elastography as a noninvasive marker of right ventricular dysfunction and prognosis in precapillary pulmonary hypertension: A pilot study"],"prefix":"10.1016","volume":"261","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0008-2638","authenticated-orcid":false,"given":"Eliauria Rosa","family":"Martins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2828-479X","authenticated-orcid":false,"given":"Andressa Alves de","family":"Carvalho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6737-1760","authenticated-orcid":false,"given":"Lu\u00eds F\u00e1bio Barbosa","family":"Botelho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9723-7340","authenticated-orcid":false,"given":"Jos\u00e9 Eymard Moraes de","family":"Medeiros Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9422-3015","authenticated-orcid":false,"given":"Helman Campos","family":"Martins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2351-6491","authenticated-orcid":false,"given":"Agostinho Hermes de","family":"Medeiros Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2789-9143","authenticated-orcid":false,"given":"Rogerio","family":"de Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8809-8783","authenticated-orcid":false,"given":"Marcelo Dantas Tavares","family":"de Melo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7603-2752","authenticated-orcid":false,"given":"Fernando","family":"Bacal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rmed.2026.109043_bib1","doi-asserted-by":"crossref","unstructured":"Kylhammar D, Kjellstr\u00f6m B, Hjalmarsson C, Jansson K, Nisell M, S\u00f6derberg S, et al. A comprehensive risk stratification at early follow-up determines prognosis in pulmonary arterial hypertension. Eur. Heart J. [Internet]. 14 de dezembro de 2018 [citado 27 de junho de 2024];39(47):4175\u20134181.","DOI":"10.1093\/eurheartj\/ehx257"},{"key":"10.1016\/j.rmed.2026.109043_bib2","unstructured":"Gali N, Hoeper MM, Humbert M, Torbicki A, Vachiery JL, Barbera JA, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension: the task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur. Heart J. [Internet]. outubro de 2009 [citado 27 de junho de 2024];30(20):2493\u20132537."},{"key":"10.1016\/j.rmed.2026.109043_bib3","unstructured":"Humbert M, Kovacs G, Hoeper MM, Badagliacca R, Berger RMF, Brida M, et al. 2022 ESC\/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: developed by the task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS). Endorsed by the International Society for Heart and Lung Transplantation (ISHLT) and the European Reference Network on rare respiratory diseases (ERN-LUNG). Eur. Heart J. [Internet]. 11 de outubro de 2022 [citado 27 de junho de 2024];43(38):3618\u20133731."},{"issue":"9","key":"10.1016\/j.rmed.2026.109043_bib4","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S2213-2600(20)30317-9","article-title":"Pulmonary vascular resistance and clinical outcomes in patients with pulmonary hypertension: a retrospective cohort study","volume":"8","author":"Maron","year":"2020","journal-title":"Lancet Respir Med [Internet]. 1o de setembro de"},{"issue":"8","key":"10.1016\/j.rmed.2026.109043_bib5","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1002\/clc.22694","article-title":"Echocardiographic evaluation of the right ventricle: clinical implications","volume":"40","author":"Dutta","year":"2017","journal-title":"Clin. Cardiol."},{"issue":"134","key":"10.1016\/j.rmed.2026.109043_bib6","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1183\/09059180.00007414","article-title":"The right ventricle in pulmonary arterial hypertension","volume":"23","author":"Naeije","year":"2014","journal-title":"Eur. Respir. Rev."},{"key":"10.1016\/j.rmed.2026.109043_bib7","article-title":"TAPSE\/sPAP ratio to improve risk assessment in pulmonary arterial hypertension","author":"Badagliacca","year":"2025","journal-title":"Circulation: Heart Fail."},{"issue":"2","key":"10.1016\/j.rmed.2026.109043_bib8","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.jhep.2009.11.018","article-title":"Liver stiffness is directly influenced by central venous pressure","volume":"52","author":"Millonig","year":"2010","journal-title":"J. Hepatol."},{"key":"10.1016\/j.rmed.2026.109043_bib9","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1136\/gut.2006.111302","article-title":"Reproducibility of transient elastography in the evaluation of liver fibrosis in patients with chronic liver disease","volume":"56","author":"Fraquelli","year":"2007","journal-title":"Gut"},{"issue":"11","key":"10.1016\/j.rmed.2026.109043_bib10","doi-asserted-by":"crossref","first-page":"3102","DOI":"10.1016\/j.ejrad.2012.05.030","article-title":"Reproducibility of real-time shear wave elastography in the evaluation of liver elasticity","volume":"81","author":"Ferraioli","year":"2012","journal-title":"Eur. J. Radiol."},{"key":"10.1016\/j.rmed.2026.109043_bib11","doi-asserted-by":"crossref","unstructured":"Castera L, Yuen Chan HL, Arrese M, Afdhal N, Bedossa P, Friedrich-Rust M, et al. EASL-ALEH clinical practice guidelines: non-invasive tests for evaluation of liver disease severity and prognosis. J. Hepatol. [Internet]. 1o de julho de 2015 [citado 27 de junho de 2024];63(1):237\u2013264.","DOI":"10.1016\/j.jhep.2015.04.006"},{"key":"10.1016\/j.rmed.2026.109043_bib12","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ahj.2022.05.006","article-title":"Prognostic value of brain natriuretic peptides in patients with pulmonary arterial hypertension: a systematic review and meta-analysis","volume":"250","author":"Hendriks","year":"2024","journal-title":"Am. Heart J."},{"issue":"5","key":"10.1016\/j.rmed.2026.109043_bib13","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.ultrasmedbio.2015.03.008","article-title":"WFUMB guidelines and recommendations for clinical use of ultrasound elastography: part 2: breast","volume":"41","author":"Barr","year":"2015","journal-title":"Ultrasound Med Biol. 1 o de maio de"},{"issue":"6","key":"10.1016\/j.rmed.2026.109043_bib14","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.jcmg.2017.10.022","article-title":"Liver stiffness reflecting right-sided filling pressure can predict adverse outcomes in patients with heart failure","volume":"12","author":"Taniguchi","year":"2019","journal-title":"JACC, Cardiovasc. Imaging"},{"issue":"4","key":"10.1016\/j.rmed.2026.109043_bib15","doi-asserted-by":"crossref","DOI":"10.1177\/20458940211054304","article-title":"Liver abnormalities in pulmonary arterial hypertension","volume":"11","author":"Nickel","year":"2021","journal-title":"Pulm. Circ."},{"issue":"1","key":"10.1016\/j.rmed.2026.109043_bib16","article-title":"Pathophysiology of the right ventricle and of the pulmonary circulation in pulmonary hypertension: an update","volume":"53","author":"Vonk","year":"2019","journal-title":"Eur. Respir. J."},{"issue":"3","key":"10.1016\/j.rmed.2026.109043_bib17","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.amjcard.2013.10.018","article-title":"Usefulness of transient elastography for noninvasive and reliable estimation of right-sided filling pressure in heart failure","volume":"113","author":"Taniguchi","year":"2014","journal-title":"Am. J. Cardiol."},{"issue":"7","key":"10.1016\/j.rmed.2026.109043_bib18","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/j.healun.2024.02.013","article-title":"Liver stiffness is associated with right heart dysfunction, cardiohepatic syndrome, and prognosis in pulmonary hypertension","volume":"43","author":"Rako","year":"2024","journal-title":"J. Heart Lung Transplant."},{"issue":"10","key":"10.1016\/j.rmed.2026.109043_bib19","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1093\/eurheartj\/ehs332","article-title":"Liver function abnormalities, clinical profile, and outcome in acute decompensated heart failure","volume":"34","author":"Nikolaou","year":"2013","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.rmed.2026.109043_bib20","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ejim.2017.10.016","article-title":"Liver disease and heart failure: back and forth","volume":"48","author":"Correale","year":"2018","journal-title":"Eur. J. Intern. Med."}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611126004117?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611126004117?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T15:43:33Z","timestamp":1793375013000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611126004117"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":20,"alternative-id":["S0954611126004117"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2026.109043","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hepatic elastography as a noninvasive marker of right ventricular dysfunction and prognosis in precapillary pulmonary hypertension: A pilot study","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2026.109043","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"109043"}}