{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T20:38:24Z","timestamp":1793911104580,"version":"4.8.0"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.rmed.2026.109137","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T23:06:31Z","timestamp":1788390391000},"page":"109137","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Pulmonary response to glucagon-like peptide-1 receptor agonist therapy in adults with cystic fibrosis-related diabetes: factors associated with improvement in FEV1"],"prefix":"10.1016","volume":"263","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4251-5737","authenticated-orcid":false,"given":"Sasan","family":"Mirfakhraee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marconi","family":"Abreu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3156-6205","authenticated-orcid":false,"given":"Akruti","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory A.","family":"Ratti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5833-3532","authenticated-orcid":false,"given":"James D.","family":"Finklea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raksha","family":"Jain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0391-7207","authenticated-orcid":false,"given":"Jessica","family":"Abramowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.rmed.2026.109137_bib1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.ccm.2015.11.009","article-title":"Nutritional issues in cystic fibrosis","volume":"37","author":"Solomon","year":"2016","journal-title":"Clin. Chest Med."},{"issue":"6","key":"10.1016\/j.rmed.2026.109137_bib2","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1177\/0884533613507086","article-title":"Malnutrition in cystic fibrosis: a review","volume":"28","author":"Culhane","year":"2013","journal-title":"Nutr. Clin. Pract."},{"issue":"2","key":"10.1016\/j.rmed.2026.109137_bib3","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1136\/thx.51.2.126","article-title":"Resting energy expenditure and oxygen cost of breathing in patients with cystic fibrosis","volume":"51","author":"Bell","year":"1996","journal-title":"Thorax"},{"issue":"18","key":"10.1016\/j.rmed.2026.109137_bib4","doi-asserted-by":"crossref","DOI":"10.3390\/nu16183103","article-title":"Is obesity a problem in new cystic fibrosis treatments?","volume":"16","author":"Solis-Garcia","year":"2024","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.rmed.2026.109137_bib5","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jcf.2024.09.022","article-title":"Development of metabolic syndrome in people with cystic fibrosis one year after exposure to elexacaftor-tezacaftor-ivacaftor","volume":"24","author":"Ratti","year":"2025","journal-title":"J. Cyst. Fibros."},{"issue":"6","key":"10.1016\/j.rmed.2026.109137_bib6","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1002\/bcp.70460","article-title":"Long-term impact of elexacaftor\/tezacaftor\/ivacaftor on pulmonary, nutritional and metabolic outcomes in homozygous F508del cystic fibrosis patients: a real-world cohort study","volume":"92","author":"Perrotta","year":"2026","journal-title":"Br. J. Clin. Pharmacol."},{"issue":"159","key":"10.1016\/j.rmed.2026.109137_bib7","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0293-2020","article-title":"Cystic fibrosis-related diabetes and lung disease: an update","volume":"30","author":"Prentice","year":"2021","journal-title":"Eur. Respir. Rev."},{"issue":"10","key":"10.1016\/j.rmed.2026.109137_bib8","doi-asserted-by":"crossref","first-page":"4744","DOI":"10.1111\/dom.15844","article-title":"Cystic fibrosis-related diabetes develops from a combination of insulin secretion defects and insulin resistance","volume":"26","author":"Bolduc","year":"2024","journal-title":"Diabetes Obes. Metabol."},{"issue":"10","key":"10.1016\/j.rmed.2026.109137_bib9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0331847","article-title":"Dysglycemia and the airway microbiome in cystic fibrosis","volume":"20","author":"Brenner","year":"2025","journal-title":"PLoS One"},{"key":"10.1016\/j.rmed.2026.109137_bib10","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/3094642","article-title":"Anti-Inflammatory effects of GLP-1-Based therapies beyond glucose control","volume":"2016","author":"Lee","year":"2016","journal-title":"Mediat. Inflamm."},{"issue":"1","key":"10.1016\/j.rmed.2026.109137_bib11","doi-asserted-by":"crossref","DOI":"10.1186\/s12931-026-03569-7","article-title":"GLP-1RAs: antidiabetic drug crossover-new hope for chronic inflammatory airway diseases","volume":"27","author":"Chen","year":"2026","journal-title":"Respir. Res."},{"issue":"12","key":"10.1016\/j.rmed.2026.109137_bib12","article-title":"Potential use of GLP-1 and GIP\/GLP-1 receptor agonists for respiratory disorders: where are we at?","volume":"60","author":"Janic","year":"2024","journal-title":"Medicina (Kaunas)"},{"issue":"1","key":"10.1016\/j.rmed.2026.109137_bib13","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jcf.2024.08.005","article-title":"Glucagon-like-peptide-1 agonist therapy in adults with cystic fibrosis","volume":"24","author":"Park","year":"2025","journal-title":"J. Cyst. Fibros."},{"key":"10.1016\/j.rmed.2026.109137_bib14","article-title":"Impact of glucagon-like-peptide-1 receptor agonist therapy on pulmonary function in people with cystic fibrosis who achieve normal body mass index","author":"Horvit","year":"2025","journal-title":"J. Cyst. Fibros."},{"key":"10.1016\/j.rmed.2026.109137_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcf.2026.05.009","article-title":"Changes in metabolic and pulmonary outcomes after discontinuation of glucagon-like-peptide-1 receptor agonist therapy in people with cystic fibrosis","author":"Singh","year":"2026","journal-title":"J. Cyst. Fibros."},{"key":"10.1016\/j.rmed.2026.109137_bib16","article-title":"Glucagon-like peptide1 receptor agonist treatment of cystic fibrosis-related diabetes complicated by obesity: a cases series and literature review","volume":"38","author":"Ahmed","year":"2024","journal-title":"J. Clin. Transl. Endocrinol."},{"issue":"4","key":"10.1016\/j.rmed.2026.109137_bib17","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1164\/ajrccm.163.4.9912132","article-title":"Glucagon-like peptide-1(7-36) amide stimulates surfactant secretion in human type II pneumocytes","volume":"163","author":"Vara","year":"2001","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"12","key":"10.1016\/j.rmed.2026.109137_bib18","doi-asserted-by":"crossref","first-page":"4503","DOI":"10.1210\/en.2013-1666","article-title":"Glucagon-like peptide-1 (GLP-1) reduces mortality and improves lung function in a model of experimental obstructive lung disease in female mice","volume":"154","author":"Viby","year":"2013","journal-title":"Endocrinology"},{"issue":"11","key":"10.1016\/j.rmed.2026.109137_bib19","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1136\/thorax-2023-221040","article-title":"Glucagon-like peptide-1 receptor agonists may benefit cardiopulmonary outcomes in patients with COPD","volume":"79","author":"Yen","year":"2024","journal-title":"Thorax"}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611126005068?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611126005068?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T20:13:49Z","timestamp":1793909629000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611126005068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":19,"alternative-id":["S0954611126005068"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2026.109137","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pulmonary response to glucagon-like peptide-1 receptor agonist therapy in adults with cystic fibrosis-related diabetes: factors associated with improvement in FEV1","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2026.109137","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"109137"}}