{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T20:37:08Z","timestamp":1793911028597,"version":"4.8.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordination for the improvement of Higher Education Personnel","doi-asserted-by":"publisher","award":["88881.218460\/2025-01"],"award-info":[{"award-number":["88881.218460\/2025-01"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.rmed.2026.109199","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:09:12Z","timestamp":1791389352000},"page":"109199","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["The effects of exercise on pulmonary function and respiratory muscle strength in patients with chronic kidney disease: a systematic review and meta-analysis"],"prefix":"10.1016","volume":"263","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0406-2212","authenticated-orcid":false,"given":"Beatriz Luiza Marinho","family":"Cunha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9393-3376","authenticated-orcid":false,"given":"Helo\u00edse","family":"Benvenutti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4046-6820","authenticated-orcid":false,"given":"Diogo V.","family":"Leal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9147-7781","authenticated-orcid":false,"given":"Jo\u00e3o L.","family":"Viana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3093-7481","authenticated-orcid":false,"given":"Patr\u00edcia \u00c9rika de Melo","family":"Marinho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7673-4241","authenticated-orcid":false,"given":"Francini Porcher","family":"Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.rmed.2026.109199_bib1","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1136\/thx.46.6.424","article-title":"Pulmonary function in chronic renal failure: effects of dialysis and transplantation","volume":"46","author":"Bush","year":"1991","journal-title":"Thorax"},{"issue":"5","key":"10.1016\/j.rmed.2026.109199_bib2","doi-asserted-by":"crossref","first-page":"L625","DOI":"10.1152\/ajplung.00152.2021","article-title":"Lung-kidney interactions and their role in chronic kidney disease-associated pulmonary diseases","volume":"322","author":"Bollenbecker","year":"2022","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"issue":"4","key":"10.1016\/j.rmed.2026.109199_bib3","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0195585","article-title":"Restrictive lung disorder is common in patients with kidney failure and associates with protein-energy wasting, inflammation and cardiovascular disease","volume":"13","author":"Mukai","year":"2018","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.rmed.2026.109199_bib4","doi-asserted-by":"crossref","first-page":"286","DOI":"10.3390\/jpm13020286","article-title":"Lung dysfunction and chronic kidney disease: a complex network of multiple interactions","volume":"13","author":"Gembillo","year":"2023","journal-title":"J Pers Med"},{"key":"10.1016\/j.rmed.2026.109199_bib5","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.12659\/MSM.897480","article-title":"Pulmonary function in patients with end-stage renal disease: effects of hemodialysis and fluid overload","volume":"22","author":"Y\u0131lmaz","year":"2016","journal-title":"Med. Sci. Monit."},{"issue":"1\u20133","key":"10.1016\/j.rmed.2026.109199_bib6","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1159\/000441271","article-title":"Intradialytic hypoxemia in chronic hemodialysis patients","volume":"41","author":"Campos","year":"2016","journal-title":"Blood Purif."},{"issue":"11","key":"10.1016\/j.rmed.2026.109199_bib7","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.2215\/CJN.02390221","article-title":"Skeletal muscle phenotype in patients undergoing long-term hemodialysis awaiting kidney transplantation","volume":"16","author":"Souweine","year":"2021","journal-title":"Clin. J. Am. Soc. Nephrol."},{"issue":"6","key":"10.1016\/j.rmed.2026.109199_bib8","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1053\/j.ajkd.2017.01.051","article-title":"Exercise and CKD: skeletal muscle dysfunction and practical application of exercise to prevent and treat physical impairments in CKD","volume":"69","author":"Roshanravan","year":"2017","journal-title":"Am. J. Kidney Dis."},{"issue":"6","key":"10.1016\/j.rmed.2026.109199_bib9","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1164\/ajrccm\/146.6.1383","article-title":"Effect of chronic renal failure on skeletal and diaphragmatic muscle contraction","volume":"146","author":"Tarasuik","year":"1992","journal-title":"Am. Rev. Respir. Dis."},{"issue":"9","key":"10.1016\/j.rmed.2026.109199_bib10","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1136\/thx.2003.009894","article-title":"Respiratory muscle fibres: specialisation and plasticity","volume":"59","author":"Polla","year":"2004","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2026.109199_bib11","first-page":"1","article-title":"Physical activity and exercise in chronic kidney disease: consensus statements from the Physical Exercise Working Group of the Italian Society of Nephrology","author":"Battaglia","year":"2024","journal-title":"J. Nephrol."},{"issue":"2","key":"10.1016\/j.rmed.2026.109199_bib12","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/sdi.13020","article-title":"Intradialytic periodized exercise improves cardiopulmonary fitness and respiratory function: a randomized controlled trial","volume":"35","author":"Andrade","year":"2021","journal-title":"Semin. Dial."},{"key":"10.1016\/j.rmed.2026.109199_bib13","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2020.572355","article-title":"Cardiovascular functional changes in chronic kidney disease: integrative physiology, pathophysiology and applications of cardiopulmonary exercise testing","volume":"11","author":"Lim","year":"2020","journal-title":"Front. Physiol."},{"issue":"3","key":"10.1016\/j.rmed.2026.109199_bib14","doi-asserted-by":"crossref","first-page":"405","DOI":"10.3390\/healthcare14030405","article-title":"Early detection of chronic kidney disease in men using lifestyle and demographic indicators: a machine learning approach for primary healthcare settings","volume":"14","author":"Valencia","year":"2026","journal-title":"Healthcare"},{"key":"10.1016\/j.rmed.2026.109199_bib15","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.rmed.2026.109199_bib16","series-title":"Acsm's Guidelines for Exercise Testing and Prescription","year":"2025"},{"key":"10.1016\/j.rmed.2026.109199_bib17","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"28","author":"Sterne","year":"2019","journal-title":"BMJ"},{"issue":"7650","key":"10.1016\/j.rmed.2026.109199_bib18","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"key":"10.1016\/j.rmed.2026.109199_bib19","first-page":"Chapter 1","author":"Higgins","year":"2024","journal-title":"Cochrane Handbook for Systematic Reviews of Interventions Version 6.1"},{"issue":"6","key":"10.1016\/j.rmed.2026.109199_bib20","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1177\/0962280216669183","article-title":"Optimally estimating the sample mean from the sample size, median, mid-range, and\/or mid-quartile range","volume":"27","author":"Luo","year":"2018","journal-title":"Stat. Methods Med. Res."},{"issue":"5","key":"10.1016\/j.rmed.2026.109199_bib21","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1002\/jrsm.1429","article-title":"Optimally estimating the sample standard deviation from the five\u2010number summary","volume":"11","author":"Shi","year":"2020","journal-title":"Res. Synth. Methods"},{"issue":"4","key":"10.1016\/j.rmed.2026.109199_bib22","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1007\/s11332-023-01053-z","article-title":"A multicomponent exercise program improves functional capacity and respiratory muscle strength in hemodialysis patients: a randomized clinical trial","volume":"19","author":"Barbosa","year":"2023","journal-title":"Sport Sci. Health"},{"issue":"3","key":"10.1016\/j.rmed.2026.109199_bib23","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.bjpt.2019.04.003","article-title":"Short period of high-intensity inspiratory muscle training improves inspiratory muscle strength in patients with chronic kidney disease on hemodialysis: a randomized controlled trial","volume":"24","author":"Dipp","year":"2020","journal-title":"Braz. J. Phys. Ther."},{"issue":"3","key":"10.1016\/j.rmed.2026.109199_bib24","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/hdi.12918","article-title":"Effectiveness of a resistance exercise program for lower limbs in chronic renal patients on hemodialysis: a randomized controlled trial","volume":"25","author":"Exel","year":"2021","journal-title":"Hemodial. Int."},{"key":"10.1016\/j.rmed.2026.109199_bib25","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/7857824","article-title":"Functional and respiratory capacity of patients with chronic kidney disease undergoing cycle ergometer training during hemodialysis sessions: a randomized clinical trial","volume":"2019","author":"Fernandes","year":"2019","journal-title":"Int J Nephrol"},{"issue":"1","key":"10.1016\/j.rmed.2026.109199_bib26","doi-asserted-by":"crossref","DOI":"10.1002\/pri.70143","article-title":"Addition of neuromuscular electrical stimulation, based on the level of excitability, to an intradialytic twice-weekly cycling protocol: a randomized trial","volume":"31","author":"Ferreira","year":"2025","journal-title":"Physiother. Res. Int."},{"issue":"8","key":"10.1016\/j.rmed.2026.109199_bib27","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1177\/0269215511431088","article-title":"Respiratory biofeedback accuracy in chronic renal failure patients: a method comparison","volume":"26","author":"Figueiredo","year":"2012","journal-title":"Clin. Rehabil."},{"issue":"5","key":"10.1016\/j.rmed.2026.109199_bib28","doi-asserted-by":"crossref","first-page":"697","DOI":"10.3109\/0886022X.2013.780977","article-title":"Effect of exercise performed during hemodialysis: strength versus aerobic","volume":"35","author":"De Lima","year":"2013","journal-title":"Ren. Fail."},{"issue":"26","key":"10.1016\/j.rmed.2026.109199_bib29","doi-asserted-by":"crossref","first-page":"3173","DOI":"10.1080\/09638288.2018.1485181","article-title":"Effects of daily inspiratory muscle training on respiratory muscle strength and chest wall regional volumes in haemodialysis patients: a randomised clinical trial","volume":"41","author":"Medeiros","year":"2018","journal-title":"Disabil. Rehabil."},{"issue":"2","key":"10.1016\/j.rmed.2026.109199_bib30","doi-asserted-by":"crossref","first-page":"189","DOI":"10.3109\/0886022X.2012.745727","article-title":"Effect of peripheral and respiratory muscle training on the functional capacity of hemodialysis patients","volume":"35","author":"Pellizzaro","year":"2013","journal-title":"Ren. Fail."},{"issue":"6","key":"10.1016\/j.rmed.2026.109199_bib31","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1007\/s40620-016-0325-2","article-title":"Respiratory muscle impairment in dialysis patients: can minimal dose of exercise limit the damage? A preliminary study in a sample of patients enrolled in the EXCITE trial","volume":"29","author":"Pomidori","year":"2016","journal-title":"J. Nephrol."},{"issue":"3","key":"10.1016\/j.rmed.2026.109199_bib32","doi-asserted-by":"crossref","first-page":"344","DOI":"10.5935\/0101-2800.20160052","article-title":"Impact of neuromuscular electrical stimulation on functional capacity of patients with chronic kidney disease on hemodialysis","volume":"38","author":"Roxo","year":"2016","journal-title":"J Bras Nefrol"},{"key":"10.1016\/j.rmed.2026.109199_bib33","article-title":"Short-term effect of respiratory muscle and diaphragmatic mobilization on pulmonary function, respiratory muscle strength, and functional capacity in hemodialysis patients with chronic kidney disease: a randomized controlled trial","author":"Vishwakarma","year":"2025","journal-title":"J. Man. Manip. Ther."},{"issue":"1","key":"10.1016\/j.rmed.2026.109199_bib34","doi-asserted-by":"crossref","DOI":"10.1002\/pri.1879","article-title":"Effectiveness of inspiratory muscle training on respiratory fitness and breathlessness in chronic renal failure: a randomized control trial","volume":"26","author":"Yuenyongchaiwat","year":"2021","journal-title":"Physiother. Res. Int."},{"key":"10.1016\/j.rmed.2026.109199_bib35","article-title":"Effects of inspiratory muscle training and deep breathing training in chronic renal failure patients: a comparison randomized control trial","author":"Yuenyongchaiwat","year":"2020","journal-title":"J Med Assoc Thai"},{"key":"10.1016\/j.rmed.2026.109199_bib36","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.10333","article-title":"Duration of hemodialysis associated with cardio-respiratory dysfunction and breathlessness: a multicenter study","volume":"8","author":"Yuenyongchaiwat","year":"2020","journal-title":"PeerJ"},{"issue":"7","key":"10.1016\/j.rmed.2026.109199_bib37","doi-asserted-by":"crossref","first-page":"926","DOI":"10.2215\/CJN.10320819","article-title":"Skeletal muscle mitochondrial dysfunction is present in patients with CKD before initiation of maintenance hemodialysis","volume":"15","author":"Gamboa","year":"2020","journal-title":"Clin. J. Am. Soc. Nephrol."},{"issue":"2","key":"10.1016\/j.rmed.2026.109199_bib38","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1152\/advan.00067.2023","article-title":"The pulmonary physiology of exercise","volume":"48","author":"Dominelli","year":"2024","journal-title":"Adv. Physiol. Educ."},{"issue":"2","key":"10.1016\/j.rmed.2026.109199_bib39","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.jphys.2017.02.016","article-title":"Inspiratory muscle training improves respiratory muscle strength, functional capacity and quality of life in patients with chronic kidney disease: a systematic review","volume":"63","author":"de Medeiros","year":"2017","journal-title":"J. Physiother."},{"issue":"1","key":"10.1016\/j.rmed.2026.109199_bib40","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1186\/s12882-020-01977-5","article-title":"Changes in pulmonary restrictive parameters by intensive home hemodialysis: a case report","volume":"21","author":"Srithongkul","year":"2020","journal-title":"BMC Nephrol."},{"issue":"3","key":"10.1016\/j.rmed.2026.109199_bib41","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1177\/02692155221135729","article-title":"Effect of respiratory muscle training in patients with chronic kidney disease: a systematic review and meta-analysis of randomized controlled trials","volume":"37","author":"Zhang","year":"2023","journal-title":"Clin. Rehabil."},{"issue":"3","key":"10.1016\/j.rmed.2026.109199_bib42","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1080\/08989621.2023.2269083","article-title":"Spin in randomized controlled trials of pharmacology in COVID-19: a systematic review","volume":"32","author":"Oh","year":"2025","journal-title":"Account. Res."}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611126005688?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611126005688?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T20:15:54Z","timestamp":1793909754000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611126005688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":42,"alternative-id":["S0954611126005688"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2026.109199","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effects of exercise on pulmonary function and respiratory muscle strength in patients with chronic kidney disease: a systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2026.109199","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"109199"}}