{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:33:08Z","timestamp":1761489188152},"reference-count":116,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revue des Maladies Respiratoires"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.rmr.2013.06.003","type":"journal-article","created":{"date-parts":[[2013,8,2]],"date-time":"2013-08-02T00:16:04Z","timestamp":1375402564000},"page":"644-656","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Quels r\u00f4les les anomalies de la voie des nucl\u00e9otides cycliques et des prot\u00e9ines G jouent-elles dans le d\u00e9sordre biochimique des lymphocytes T dans la sarco\u00efdose\u00a0?"],"prefix":"10.1016","volume":"30","author":[{"given":"Y.","family":"Pacheco","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Calender","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Valeyre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Lebecque","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rmr.2013.06.003_bib0005","series-title":"Trait\u00e9 des maladies et syndromes syst\u00e9miques","first-page":"1264","article-title":"Sarco\u00efdose","author":"Valeyre","year":"2008"},{"key":"10.1016\/j.rmr.2013.06.003_bib0010","first-page":"L240","article-title":"Regulation of alveolar macrophage T cell interactions during Th1-type sarcoid inflammatory process","volume":"277","author":"Agostini","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0015","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1513\/pats.200606-130MS","article-title":"Role of CD4+ T cells in sarcoidosis","volume":"4","author":"Grunewald","year":"2007","journal-title":"Proc Am Thorac Soc"},{"key":"10.1016\/j.rmr.2013.06.003_bib0020","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1164\/ajrccm.163.1.9906071","article-title":"Analysis of intracellular cytokines in CD4+ and CD8+ lung and blood T cells in sarcoidosis","volume":"163","author":"Wahlstrom","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmr.2013.06.003_bib0025","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1136\/thorax.56.6.487","article-title":"Intracellular cytokine repertoire in different T cell subsets from patients with sarcoidosis","volume":"56","author":"Mollers","year":"2001","journal-title":"Thorax"},{"key":"10.1016\/j.rmr.2013.06.003_bib0030","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1164\/ajrccm.160.4.9807120","article-title":"Increased expression of IL-12\u00a0receptor mRNA in active pulmonary tuberculosis and sarcoidosis","volume":"160","author":"Taha","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmr.2013.06.003_bib0035","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/0002-9343(82)90930-5","article-title":"Flow cytometry analysis of T lymphocytes in sarcoidosis","volume":"73","author":"Pacheco","year":"1982","journal-title":"Am J Med"},{"key":"10.1016\/j.rmr.2013.06.003_bib0040","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1136\/thorax.57.10.897","article-title":"Apoptosis resistant bronchoalveolar lavage (BAL) fluid lymphocytes in sarcoidosis","volume":"57","author":"Stridh","year":"2002","journal-title":"Thorax"},{"key":"10.1016\/j.rmr.2013.06.003_bib0045","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1046\/j.1365-2249.2000.01365.x","article-title":"Th1\u00a0cytokine pattern in sarcoidosis is expressed by bronchoalveolar CD4+ and CD8T cells","volume":"122","author":"Prasse","year":"2000","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0050","doi-asserted-by":"crossref","first-page":"746","DOI":"10.4049\/jimmunol.181.1.746","article-title":"The anergic state in sarcoidosis is associated with diminished dendritic cell function","volume":"181","author":"Mathew","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0055","first-page":"89","article-title":"Cellular immunity in sarcoidosis. Evidence for an intrinsic defect of effector cell function","volume":"118","author":"Faguet","year":"1978","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.rmr.2013.06.003_bib0060","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1084\/jem.20050648","article-title":"The immune paradox of sarcoidosis and regulatory cells","volume":"203","author":"Miyara","year":"2006","journal-title":"J Exp Med"},{"key":"10.1016\/j.rmr.2013.06.003_bib0065","doi-asserted-by":"crossref","first-page":"497","DOI":"10.2353\/ajpath.2009.080580","article-title":"FoxP3+ regulatory T cells suppress early stages of granuloma formation but have little impact on sarcoidosis lesions","volume":"174","author":"Taflin","year":"2009","journal-title":"Am J Pathol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0070","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1111\/j.1751-2980.2010.00428.x","article-title":"TH17\u00a0cells: the emerging reciprocal partner of regulatory T cells in the liver","volume":"11","author":"Zhao","year":"2010","journal-title":"J Dig Dis"},{"key":"10.1016\/j.rmr.2013.06.003_bib0075","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1136\/thx.2010.140319","article-title":"Sarcoidosis is a TH1\/TH17\u00a0multisystem disorder","volume":"66","author":"Facco","year":"2011","journal-title":"Thorax"},{"key":"10.1016\/j.rmr.2013.06.003_bib0080","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1365-2249.2008.03609.x","article-title":"Analysis of regulatory T cell associated forkhead box P3\u00a0expression in the lungs of patients with sarcoidosis","volume":"152","author":"Idali","year":"2008","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0085","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1183\/09031936.00055210","article-title":"Impaired function of regulatory T cells in hypersensitivity pneumonitis","volume":"37","author":"Girard","year":"2011","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmr.2013.06.003_bib0090","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1164\/rccm.201001-0025OC","article-title":"Deficient and dysfunctional regulatory T cells in the lungs of chronic beryllium disease subjects","volume":"181","author":"Mack","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmr.2013.06.003_bib0095","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1365-2362.1993.tb00713.x","article-title":"Impaired G proteins and cyclic nucleotide. Phosphodiesterase activity in T lymphocytes from patients with sarcoidosis","volume":"23","author":"Nemoz","year":"1993","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.rmr.2013.06.003_bib0100","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.clim.2009.04.010","article-title":"Hypothesis: sarcoidosis is a STAT1-mediated disease","volume":"132","author":"Rosenbaum","year":"2009","journal-title":"Clin Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0105","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1164\/rccm.201005-0792OC","article-title":"Dysregulation of p38\u00a0and MKP1\u00a0in response to NOD1\/TLR4\u00a0stimulation in sarcoid bronchoalveolar cells","volume":"183","author":"Rastogi","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmr.2013.06.003_bib0110","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1128\/CVI.00469-10","article-title":"Low levels of NF-\u03baB\/p65\u00a0mark anergic CD4+ T cells and correlate with disease severity in sarcoidosis","volume":"18","author":"Lee","year":"2011","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0115","first-page":"9","article-title":"Expression of IL-2\u00a0receptor in peripheral blood lymphocytes and bronchoalveolar lavage fluid (BAL) in patients with sarcoidosis","volume":"99","author":"Koktysz","year":"1998","journal-title":"Pol Arch Med Wewn"},{"key":"10.1016\/j.rmr.2013.06.003_bib0120","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/j.1365-2249.2009.04076.x","article-title":"T cell activation profiles in different granulomatous interstitial lung diseases: a role for CD8+ CD28 (null) cells","volume":"160","author":"Heron","year":"2010","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0125","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.it.2012.01.010","article-title":"Metabolic pathways in T cell fate and function","volume":"33","author":"Gerriets","year":"2012","journal-title":"Trends Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.it.2011.09.002","article-title":"Intracellular metabolic pathways control immune tolerance","volume":"33","author":"Procaccini","year":"2012","journal-title":"Trends Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0135","doi-asserted-by":"crossref","first-page":"5406","DOI":"10.1128\/MCB.00217-10","article-title":"Cyclic AMP controls mTOR through regulation of the dynamic interaction between Rheb and phosphodiesterase 4D","volume":"30","author":"Kim","year":"2010","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0140","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1189\/jlb.69.6.1053","article-title":"Suppression of T cell responsiveness by inducible cAMP early repressor","volume":"69","author":"Bodor","year":"2001","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0145","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1042\/BST0340476","article-title":"The molecular machinery for cAMP-dependent immunomodulation in T cells","volume":"34","author":"Tasken","year":"2006","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.rmr.2013.06.003_bib0150","doi-asserted-by":"crossref","first-page":"3177","DOI":"10.4049\/jimmunol.1100206","article-title":"Gai2\u00a0and ZAP-70\u00a0mediate RasGRP1\u00a0membrane localization and activation of SDF-1-induced T cell functions","volume":"187","author":"Kremer","year":"2011","journal-title":"J Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0155","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1038\/nri1248","article-title":"CD28-mediated co-stimulation: a quantitative support for TCR signalling","volume":"3","author":"Acuto","year":"2003","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0160","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1152\/physrev.00021.2003","article-title":"Locolized effects of cAMP mediated by distinct routes of protein kinase A","volume":"84","author":"Tasken","year":"2004","journal-title":"Physiol Rev"},{"key":"10.1016\/j.rmr.2013.06.003_bib0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0079-6603(08)60718-7","article-title":"The molecular biology of cyclic nucleotide phosphodiesterases","volume":"63","author":"Conti","year":"1999","journal-title":"Prog Nucleic Acid Res Mol Biol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0170","doi-asserted-by":"crossref","first-page":"4820","DOI":"10.4049\/jimmunol.178.8.4820","article-title":"Diffential expression and function of phosphodiesterase 4 (PDE4) subtypes in human primary CD4+ T cells: predominant role of PDE4D","volume":"178","author":"Peter","year":"2007","journal-title":"J Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0175","doi-asserted-by":"crossref","first-page":"4847","DOI":"10.4049\/jimmunol.173.8.4847","article-title":"TCR and CD28-mediated recruitment of phosphodiesterases 4\u00a0to lipid rafts potentiates TCR signalling","volume":"173","author":"Abrahamsen","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.imlet.2010.01.007","article-title":"Novel mechanism of signaling by CD28","volume":"129","author":"Bjorgo","year":"2010","journal-title":"Immunol Lett"},{"key":"10.1016\/j.rmr.2013.06.003_bib0185","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1084\/jem.20062129","article-title":"Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression","volume":"204","author":"Bopp","year":"2007","journal-title":"J Exp Med"},{"key":"10.1016\/j.rmr.2013.06.003_bib0190","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1126\/science.1079490","article-title":"Control of regulatory T cell development by the transcription factor FOXP3","volume":"299","author":"Hori","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.rmr.2013.06.003_bib0195","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1183\/09031936.00120410","article-title":"Transforming growth factor (beta) gene polymorphisms in different phenotypes of sarcoidosis","volume":"38","author":"Pabst","year":"2011","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmr.2013.06.003_bib0200","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1513\/pats.200701-020AW","article-title":"Regulatory T cells, transforming growth factor-beta, and immune suppression","volume":"4","author":"Wan","year":"2007","journal-title":"Proc Am Thorac Soc"},{"key":"10.1016\/j.rmr.2013.06.003_bib0205","doi-asserted-by":"crossref","first-page":"13445","DOI":"10.1073\/pnas.0901944106","article-title":"GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells","volume":"106","author":"Tran","year":"2009","journal-title":"Proc Nat Acad Sci U S A"},{"key":"10.1016\/j.rmr.2013.06.003_bib0210","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1006\/jmcc.2002.2073","article-title":"TGF-beta regulates the expression of G alpha (i2) via an effect on the localization of RAS","volume":"34","author":"Ward","year":"2002","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0215","doi-asserted-by":"crossref","first-page":"4301","DOI":"10.4049\/jimmunol.142.12.4301","article-title":"Signal transduction pathway for Il1. Involvement of a pertussis toxin sensitive GTP binding protein in the activation of adenylate cyclase","volume":"142","author":"Chedid","year":"1989","journal-title":"J Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0220","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1126\/science.271.5253.1276","article-title":"Blocked Ras activation in anergic CD4+ T cells","volume":"271","author":"Fields","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.rmr.2013.06.003_bib0225","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1126\/science.278.5335.124","article-title":"Maintenance of human T cell anergy: blocking of IL-2\u00a0gene transcription by activated Rap1","volume":"278","author":"Boussiotis","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.rmr.2013.06.003_bib0230","doi-asserted-by":"crossref","first-page":"13375","DOI":"10.1074\/jbc.M312660200","article-title":"AGS3\u00a0and signal integration by Galpha(s)- and Galpha(i)-coupled receptors: AGS3\u00a0blocks the sensitization of adenylyl cyclase following prolonged stimulation of a Galpha(i)-coupled receptor by influencing processing of Galpha(i)","volume":"279","author":"Sato","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.rmr.2013.06.003_bib0235","doi-asserted-by":"crossref","first-page":"27567","DOI":"10.1074\/jbc.M312786200","article-title":"Identification and characterization of AGS4; a protein containing three G protein regulatory motifs that regulate the activation state of Gialpha","volume":"279","author":"Cao","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.rmr.2013.06.003_bib0240","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.4049\/jimmunol.171.3.1542","article-title":"Role of regulator of G protein signaling 16\u00a0in inflammation induced T lymphocyte migration and activation","volume":"171","author":"Lippert","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0245","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.4049\/jimmunol.162.5.2677","article-title":"Regulators of G protein signaling exhibit distinct patterns of gene expression and target G protein specificity in human lymphocytes","volume":"162","author":"Beadling","year":"1999","journal-title":"J Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0250","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.intimp.2010.11.008","article-title":"FOXP3\u00a0and RORgt: transcriptional regulation of Treg and Th17","volume":"11","author":"Chen","year":"2011","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0255","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1038\/ni1261","article-title":"A distinct lineage of CD4\u00a0T cells regulates tissue inflammation by producing interleukin 17","volume":"6","author":"Park","year":"2005","journal-title":"Nat Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0260","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.molimm.2008.12.019","article-title":"Properties and origin of human TH17\u00a0cells","volume":"47","author":"Romagnani","year":"2009","journal-title":"Mol Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0265","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.cytogfr.2011.02.003","article-title":"IL-6\u00a0signaling in auto-immunity, chronic inflammation and inflammation-associated cancer","volume":"22","author":"Neurath","year":"2011","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/j.rmr.2013.06.003_bib0270","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1084\/jem.20070109","article-title":"CREB\/ATF-dependent T cell receptor-induced Foxp3\u00a0gene expression: a role for DNA methylation","volume":"204","author":"Kim","year":"2007","journal-title":"J Exp Med"},{"key":"10.1016\/j.rmr.2013.06.003_bib0275","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1126\/science.1172702","article-title":"CD4+ regulatory T cells control TH17\u00a0responses in a STAT3\u00a0dependent manner","volume":"326","author":"Chaudhry","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.rmr.2013.06.003_bib0280","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1038\/ni.1663","article-title":"Interactions among the transcription factors Runx1, ROR gamma t and FOXP3\u00a0regulate the differentiation of interleukin17\u00a0producing T cells","volume":"9","author":"Zhang","year":"2008","journal-title":"Nat Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0285","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/eji.200425524","article-title":"Adenosine and cAMP are potent inhibitors of the NF-kappa B pathway downstream of immunoreceptors","volume":"35","author":"Minguet","year":"2005","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0290","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1074\/jbc.M110.203406","article-title":"Multiple scaffolding functions of (beta)-arrestins in the degradation of G protein-coupled receptor kinase 2","volume":"262","author":"Nogues","year":"2011","journal-title":"J Biol Chem"},{"key":"10.1016\/j.rmr.2013.06.003_bib0295","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1038\/ni1489","article-title":"Critical regulation of CD4+ T cell survival and auto-immunity by beta-arrestin 1","volume":"8","author":"Shi","year":"2007","journal-title":"Nat Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0300","doi-asserted-by":"crossref","first-page":"74ra23","DOI":"10.1126\/scitranslmed.3001564","article-title":"(beta)-Arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix","volume":"3","author":"Lovgren","year":"2011","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.rmr.2013.06.003_bib0305","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.revmed.2010.09.011","article-title":"\u00c9thiopathog\u00e9nie de la sarco\u00efdose","volume":"32","author":"Pacheco","year":"2011","journal-title":"Rev Med Interne"},{"key":"10.1016\/j.rmr.2013.06.003_bib0310","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1172\/JCI113715","article-title":"Bias toward use of a specific T cell receptor beta-chain variable region in a subgroup of individuals with sarcoidosis","volume":"82","author":"Moller","year":"1988","journal-title":"J Clin Invest"},{"key":"10.1016\/j.rmr.2013.06.003_bib0315","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1172\/JCI117494","article-title":"Selective activation and accumulation of oligoclonal V beta-specific T cells in active pulmonary sarcoidosis","volume":"94","author":"Forman","year":"1994","journal-title":"J Clin Invest"},{"key":"10.1016\/j.rmr.2013.06.003_bib0320","doi-asserted-by":"crossref","first-page":"3576","DOI":"10.1172\/JCI32401","article-title":"Identification of HLA-DR-bound peptides presented by human bronchoalveolar lavage cells in sarcoidosis","volume":"117","author":"Wahlstr\u00f6m","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1016\/j.rmr.2013.06.003_bib0325","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1513\/pats.200608-155MS","article-title":"Potential etiologic agents in sarcoidosis","volume":"4","author":"Moller","year":"2007","journal-title":"Proc Am Thorac Soc"},{"key":"10.1016\/j.rmr.2013.06.003_bib0330","doi-asserted-by":"crossref","first-page":"8784","DOI":"10.4049\/jimmunol.181.12.8784","article-title":"T cell responses to mycobacterial catalase-peroxidase profile a pathogenic antigen in systemic sarcoidosis","volume":"181","author":"Chen","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0335","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1111\/j.1365-2249.2007.03510.x","article-title":"Multiple mycobacterium antigens induce interferon-gamma production from sarcoidosis peripheral blood mononuclear cells","volume":"150","author":"Carlisle","year":"2007","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0340","doi-asserted-by":"crossref","first-page":"3686","DOI":"10.1242\/jcs.03091","article-title":"cAMP synthesis and degradation by phagosomes regulate actin assembly and fusion events: consequences for mycobacteria","volume":"119","author":"Kalamidas","year":"2006","journal-title":"J Cell Sci"},{"key":"10.1016\/j.rmr.2013.06.003_bib0345","first-page":"24","article-title":"Human genes in TB infection: their role in immune response","volume":"69","author":"Lykouras","year":"2008","journal-title":"Monaldi Arch Chest Dis"},{"key":"10.1016\/j.rmr.2013.06.003_bib0350","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1086\/596742","article-title":"IFN, gamma IFN production during active tuberculosis is regulated by mechanisms that involve IL-17, SLAM and CREB","volume":"199","author":"Pasquinelli","year":"2009","journal-title":"J Infect Dis"},{"key":"10.1016\/j.rmr.2013.06.003_bib0355","doi-asserted-by":"crossref","first-page":"46278","DOI":"10.1074\/jbc.M304721200","article-title":"Oncogenic Ki-ras inhibits the expression of interferon-responsive genes through inhibition of STAT1\u00a0and STAT2\u00a0expression","volume":"278","author":"Klampfer","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.rmr.2013.06.003_bib0360","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.4161\/cc.8.13.8891","article-title":"Stat1\u00a0is an inhibitor of Ras-MAPK signalling and Rho small GTPase expression with implications in the transcriptional signature of Ras transformed cells","volume":"8","author":"Wang","year":"2009","journal-title":"Cell Cycle"},{"key":"10.1016\/j.rmr.2013.06.003_bib0365","first-page":"1503","article-title":"Retroviral infection as a putative pathogen for sarcoidosis","volume":"52","author":"Tamura","year":"1994","journal-title":"Nippon Rinsho"},{"key":"10.1016\/j.rmr.2013.06.003_bib0370","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1165\/ajrcmb.16.4.9115754","article-title":"Alveolar macrophage produce the Env protein of a human endogemous retrovirus, HERV-E4-1, in a subgroup of interstitial lung diseases","volume":"16","author":"Tamura","year":"1997","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0375","doi-asserted-by":"crossref","first-page":"3788","DOI":"10.1182\/blood-2008-04-154286","article-title":"Human T cell leukaemia virus type-1\u00a0antisense-encoded gene, HBZ, promotes T lymphocyte proliferation","volume":"112","author":"Arnold","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.rmr.2013.06.003_bib0380","doi-asserted-by":"crossref","first-page":"8732","DOI":"10.1128\/JVI.00487-10","article-title":"Elevated cyclic AMP levels in T lymphocytes transformed by human T cell lymphotropic virus type-1","volume":"84","author":"Kress","year":"2010","journal-title":"J Virol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0385","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s00109-006-0104-y","article-title":"Proliferation and cell-cell fusion of endometrial carcinoma are induced by the human endogenous retroviral Syncitin-1\u00a0and regulated by TGF-beta","volume":"85","author":"Stick","year":"2007","journal-title":"J Mol Med"},{"key":"10.1016\/j.rmr.2013.06.003_bib0390","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1183\/09031936.01.00106201","article-title":"Major histocompatibility locus genetic markers of beryllium sensitization and disease","volume":"18","author":"Saltini","year":"2001","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmr.2013.06.003_bib0395","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1189\/jlb.71.3.487","article-title":"Beryllium fluoride-induced cell proliferation: a process requiring P21 (ras)-dependent activated signal transduction and NF-kappaB-dependent gene regulation","volume":"71","author":"Misra","year":"2002","journal-title":"J Leuk Biol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0400","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1513\/pats.200607-138MS","article-title":"Lesson learned form ACCESS (a case controlled etiologic study of sarcoidosis)","volume":"4","author":"Rossman","year":"2007","journal-title":"Proc Am Thorac Soc"},{"key":"10.1016\/j.rmr.2013.06.003_bib0405","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.taap.2010.07.017","article-title":"Organophosphorous pesticide metabolite (DEDTP) induces changes in the activation status of human lymphocytes by modulating the interleukin 2\u00a0receptor signal transduction pathway","volume":"248","author":"Esquivel-Senties","year":"2010","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0410","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.toxlet.2007.09.004","article-title":"Fenvalerate inhibitis progesterone production through cAMP-dependent signal pathway","volume":"176","author":"Qu","year":"2008","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.rmr.2013.06.003_bib0415","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1016\/j.rmed.2006.03.004","article-title":"Sarcoidosis after treatment with interferon alpha and review of the literature","volume":"100","author":"Goldberg","year":"2006","journal-title":"Respir Med"},{"key":"10.1016\/j.rmr.2013.06.003_bib0420","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.4049\/jimmunol.181.3.2056","article-title":"CREB, ATF and AP1\u00a0transcription factors regulate IFN gamma secretion by human T cells in response to mycobacterial antigen","volume":"181","author":"Samten","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0425","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1159\/000161122","article-title":"Anti-CTLA4\u00a0monoclonal antibody induced sarcoidosis in a metastatic melanoma patient","volume":"218","author":"Eckert","year":"2009","journal-title":"Dermatology"},{"key":"10.1016\/j.rmr.2013.06.003_bib0430","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.1128\/MCB.01282-09","article-title":"Vasoactive intestinal peptide induces cell cycle arrest and regulatory functions in human T cells at multiple levels","volume":"30","author":"Anderson","year":"2010","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0435","first-page":"817","article-title":"Sarcoid-like granulomatous disease following etanercept treatment for RA","volume":"55","author":"Kudrin","year":"2006","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.rmr.2013.06.003_bib0440","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/BF00403881","article-title":"Chromosome analysis in patients with sarcoidosis","volume":"268","author":"Veien","year":"1980","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.rmr.2013.06.003_bib0445","first-page":"199","article-title":"\u00c9tude caryotypique des lymphocytes sanguins dans la sarco\u00efdose","volume":"45","author":"Pacheco","year":"1989","journal-title":"Rev Pneumol Clin"},{"key":"10.1016\/j.rmr.2013.06.003_bib0450","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1164\/ajrccm.164.5.2007056","article-title":"Results from a genome-wide search for predisposing genes in sarcoidosis","volume":"164","author":"Schurmann","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmr.2013.06.003_bib0455","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1086\/444435","article-title":"The BTNL2\u00a0gene and sarcoidosis susceptibility in African Americans and whites","volume":"77","author":"Rybicki","year":"2005","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.rmr.2013.06.003_bib0460","first-page":"712","article-title":"Impact of rheumatoid arthritis associated HLA-DRbeta1\u00a0subtypes on protein kinase A signaling","volume":"116","author":"Li","year":"2003","journal-title":"Chin Med J"},{"key":"10.1016\/j.rmr.2013.06.003_bib0465","first-page":"187","article-title":"Antagonists of cyclic nucleotide phosphodiesterase (PDE) isozymes PDE3\u00a0and PDE4\u00a0suppress lymphoblastic response to HLA class II alloantigens: a potential novel approach to preventing allograft rejection?","volume":"47","author":"Dousa","year":"1997","journal-title":"Clin Nephrol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0470","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1002\/eji.200838992","article-title":"MHC class II molecules activate NFAT and the ERK group of MAPK through distinct signalling pathway in B cells","volume":"39","author":"Haylett","year":"2009","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0475","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.imbio.2008.10.008","article-title":"The pivotal role of p38\u00a0and NF-kappa B signal pathway in the maturation of monocyte derived dendritic cells stimulated by streptococcal agent OK-432","volume":"214","author":"Pan","year":"2009","journal-title":"Immunobiology"},{"key":"10.1016\/j.rmr.2013.06.003_bib0480","first-page":"10","article-title":"Functional genomics and prognosis in sarcoidosis: the critical role of antigen presentation","volume":"21","author":"Rutherford","year":"2004","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"10.1016\/j.rmr.2013.06.003_bib0485","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1086\/378097","article-title":"HLA-DRB1*1101: a significant risk factor for sarcoidosis in blacks and whites","volume":"73","author":"Rossman","year":"2003","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.rmr.2013.06.003_bib0490","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/ng1519","article-title":"Sarcoidosis is associated with a truncating splice site mutation in BTNL2","volume":"37","author":"Valentonyte","year":"2005","journal-title":"Nat Genet"},{"key":"10.1016\/j.rmr.2013.06.003_bib0495","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1378\/chest.127.1.251","article-title":"Production of soluble tumor necrosis factor receptors and tumor necrosis factor-alpha by alveolar macrophages in sarcoidosis and extrinsic allergic alveolitis","volume":"127","author":"Dai","year":"2005","journal-title":"Chest"},{"key":"10.1016\/j.rmr.2013.06.003_bib0500","doi-asserted-by":"crossref","first-page":"2796","DOI":"10.4049\/jimmunol.180.5.2796","article-title":"Notch1\u00a0signaling and regulatory T cell function","volume":"180","author":"Asano","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0505","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.it.2007.02.005","article-title":"The unconventional role of Lt alpha beta in T cell differentiation","volume":"28","author":"Elewaut","year":"2007","journal-title":"Trends Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0510","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1006\/cyto.1997.0224","article-title":"Tumor necrosis factor-alpha promoter gene polymorphism in sarcoidosis","volume":"9","author":"Seitzer","year":"1997","journal-title":"Cytokine"},{"key":"10.1016\/j.rmr.2013.06.003_bib0515","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1399-0039.2005.00370.x","article-title":"Association of tumor necrosis factor-alpha, lymphotoxin-alpha and HLA-DRB1\u00a0gene polymorphisms with Lofgren's syndrome in Czech patients with sarcoidosis","volume":"65","author":"Mrazch","year":"2005","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.rmr.2013.06.003_bib0520","doi-asserted-by":"crossref","first-page":"ra28","DOI":"10.1126\/scisignal.2000202","article-title":"Suppresion of LPS induced TNF-alpha production macrophages by cAMP is mediated by PKA-AKAP95-p105","volume":"2","author":"Wall","year":"2009","journal-title":"Sci Signal"},{"key":"10.1016\/j.rmr.2013.06.003_bib0525","first-page":"1313","article-title":"Differential regulation of human monocyte TNF-alpha and IL1\u00a0beta by typeIV cAMP phosphodiesterase inhibitors","volume":"272","author":"Verghese","year":"1995","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.rmr.2013.06.003_bib0530","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1159\/000327254","article-title":"Qualitative evaluation of adjuvant activities and its appication to TH2\/17\u00a0diseases","volume":"155","author":"Matsushita","year":"2011","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0535","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1182\/blood-2004-07-2972","article-title":"Early-onset sarcoidosis and CARD15\u00a0mutations with constitutive nuclear factor-kB activation: common genetic etiology with Blau syndrome","volume":"105","author":"Kanazawa","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.rmr.2013.06.003_bib0540","doi-asserted-by":"crossref","first-page":"29318","DOI":"10.1074\/jbc.M002725200","article-title":"Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation","volume":"275","author":"Yi","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.rmr.2013.06.003_bib0545","first-page":"522","article-title":"Update on glucocorticoid action and resistance","volume":"117","author":"Ito","year":"2006","journal-title":"JACI"},{"key":"10.1016\/j.rmr.2013.06.003_bib0550","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1128\/MCB.18.4.1783","article-title":"Characterization of STAT5a and STAT5b homodimers and heterodimers and their association with the glucocorticoid receptor in mammary cells","volume":"18","author":"Cella","year":"1998","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.rmr.2013.06.003_bib0555","first-page":"3","article-title":"Update on glucocorticoid action and resistance","volume":"11","author":"Leung","year":"2003","journal-title":"JACI"},{"key":"10.1016\/j.rmr.2013.06.003_bib0560","first-page":"649","article-title":"P38\u00a0MAPkinase induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid insensitive asthma","volume":"109","author":"Irusen","year":"2002","journal-title":"JACI"},{"key":"10.1016\/j.rmr.2013.06.003_bib0565","first-page":"1425","article-title":"Glucocorticoid upregulate FOXP3\u00a0expression and regulatory T cells in asthma","volume":"114","author":"Karagiannidis","year":"2004","journal-title":"JACI"},{"key":"10.1016\/j.rmr.2013.06.003_bib0570","first-page":"107","article-title":"Azathioprine treatment of chronic pulmonary sarcoidosis","volume":"2","author":"Pacheco","year":"1985","journal-title":"Sarcoidosis"},{"key":"10.1016\/j.rmr.2013.06.003_bib0575","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1172\/JCI16432","article-title":"CD28\u00a0dependent Rac1\u00a0activation is the molecular target of azathioprine in primary human CD4\u00a0T lymphocytes","volume":"11","author":"Tiede","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1016\/j.rmr.2013.06.003_bib0580","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.tox.2008.11.016","article-title":"Inflammation in methotrexate induced pulmonary toxicity occurs via the p38\u00a0MAPK pathway","volume":"256","author":"Kim","year":"2009","journal-title":"Toxicology"}],"container-title":["Revue des Maladies Respiratoires"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0761842513002106?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0761842513002106?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T16:35:26Z","timestamp":1688402126000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0761842513002106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":116,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["S0761842513002106"],"URL":"https:\/\/doi.org\/10.1016\/j.rmr.2013.06.003","relation":{},"ISSN":["0761-8425"],"issn-type":[{"value":"0761-8425","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quels r\u00f4les les anomalies de la voie des nucl\u00e9otides cycliques et des prot\u00e9ines G jouent-elles dans le d\u00e9sordre biochimique des lymphocytes T dans la sarco\u00efdose\u00a0?","name":"articletitle","label":"Article Title"},{"value":"Revue des Maladies Respiratoires","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmr.2013.06.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 SPLF. Published by Elsevier Masson SAS All rights reserved.","name":"copyright","label":"Copyright"}]}}