{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:10:49Z","timestamp":1786122649933,"version":"build-2736575974"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revue des Maladies Respiratoires"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.rmr.2026.06.003","type":"journal-article","created":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T11:21:57Z","timestamp":1786101717000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Apport du scanner pour le ph\u00e9notypage de l\u2019asthme s\u00e9v\u00e8re"],"prefix":"10.1016","author":[{"given":"M.-P.","family":"Debray","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Taill\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rmr.2026.06.003_bib0120","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1164\/rccm.200711-1754OC","article-title":"Cluster analysis and clinical asthma phenotypes","volume":"178","author":"Haldar","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmr.2026.06.003_bib0125","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1164\/rccm.200906-0896OC","article-title":"National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program","volume":"181","author":"Moore","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmr.2026.06.003_bib0130","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1016\/j.chest.2025.10.047","article-title":"Impact of mepolizumab on airway remodeling and inflammation in severe eosinophilic asthma","volume":"169","author":"Taill\u00e9","year":"2026","journal-title":"Chest"},{"key":"10.1016\/j.rmr.2026.06.003_bib0135","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1080\/02770903.2019.1585872","article-title":"Omalizumab may decrease the thickness of the reticular basement membrane and fibronectin deposit in the bronchial mucosa of severe allergic asthmatics","volume":"57","author":"Zastrze\u017cy\u0144ska","year":"2020","journal-title":"J Asthma"},{"key":"10.1016\/j.rmr.2026.06.003_bib0140","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.acra.2014.12.026","article-title":"Computed tomography assessment of airways throughout bronchial tree demonstrates airway narrowing in severe asthma","volume":"22","author":"Brillet","year":"2015","journal-title":"Acad Radiol"},{"key":"10.1016\/j.rmr.2026.06.003_bib0145","doi-asserted-by":"crossref","first-page":"2446","DOI":"10.1183\/09031936.97.10112446","article-title":"Significance of emphysema observed on computed tomography scan in asthma","volume":"10","author":"Paganin","year":"1997","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmr.2026.06.003_bib0150","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.chest.2017.11.016","article-title":"Further studies of unsuspected emphysema in nonsmoking patients with asthma with persistent expiratory airflow obstruction","volume":"153","author":"Gelb","year":"2018","journal-title":"Chest"},{"key":"10.1016\/j.rmr.2026.06.003_bib0155","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.jaci.2013.09.039","article-title":"Quantitative computed tomography-derived clusters: redefining airway remodeling in asthmatic patients","volume":"133","author":"Gupta","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.rmr.2026.06.003_bib0160","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.jaci.2016.11.053","article-title":"National Heart, Lung and Blood Institute's Severe Asthma Research Program. Quantitative computed tomographic imaging-based clustering differentiates asthmatic subgroups with distinctive clinical phenotypes","volume":"140","author":"Choi","year":"2017","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.rmr.2026.06.003_bib0165","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1148\/radiol.210363","article-title":"NHLBI Severe Asthma Research Program (SARP). Quantitative CT characteristics of cluster phenotypes in the Severe Asthma Research Program Cohorts","volume":"304","author":"Trivedi","year":"2022","journal-title":"Radiology"},{"key":"10.1016\/j.rmr.2026.06.003_bib0170","doi-asserted-by":"crossref","first-page":"00117","DOI":"10.1183\/23120541.00117-2020","article-title":"Focal bronchial dilatations after thermoplasty for severe asthma","volume":"6","author":"Thibaut de M\u00e9nonville","year":"2020","journal-title":"ERJ Open Res"},{"key":"10.1016\/j.rmr.2026.06.003_bib0175","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.jaip.2022.10.004","article-title":"Multifocal bronchial stenosis and extensive lobar atelectasis as a rare radiologic feature of severe eosinophilic asthma","volume":"11","author":"Phillips-Houlbracq","year":"2023","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.rmr.2026.06.003_bib0180","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1136\/jcp.13.1.27","article-title":"The pathology of asthma, with special reference to changes in the bronchial mucosa","volume":"13","author":"Dunnill","year":"1960","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.rmr.2026.06.003_bib0185","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1016\/S0012-3692(15)31431-8","article-title":"High-resolution CT findings in patients with near-fatal asthma: comparison of patients with mild-to-severe asthma and normal control subjects and changes in airway abnormalities following steroid treatment","volume":"126","author":"Lee","year":"2004","journal-title":"Chest"},{"key":"10.1016\/j.rmr.2026.06.003_bib0190","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.alit.2024.03.001","article-title":"Eosinophil-mucus interplay in severe asthma: implications for treatment with biologicals","volume":"73","author":"Venegas Garrido","year":"2024","journal-title":"Allergol Int"},{"key":"10.1016\/j.rmr.2026.06.003_bib0195","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1164\/rccm.202110-2265OC","article-title":"Mucus plugs persist in asthma, and changes in mucus plugs associate with changes in airflow over time","volume":"205","author":"Tang","year":"2022","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmr.2026.06.003_bib0200","doi-asserted-by":"crossref","first-page":"e174124","DOI":"10.1172\/jci.insight.174124","article-title":"Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma","volume":"9","author":"Huang","year":"2024","journal-title":"JCI Insight"},{"key":"10.1016\/j.rmr.2026.06.003_bib0205","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1172\/JCI95693","article-title":"National Heart Lung and Blood Institute (NHLBI) Severe Asthma Research Program (SARP). Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction","volume":"128","author":"Dunican","year":"2018","journal-title":"J Clin Invest"},{"key":"10.1016\/j.rmr.2026.06.003_bib0210","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.anai.2023.07.010","article-title":"An asthma phenotype comprising bronchial wall thickening and mucus plugging confers worse clinical outcomes","volume":"131","author":"Chan","year":"2023","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.rmr.2026.06.003_bib0215","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.chest.2022.03.003","article-title":"Asthma control, airway mucus, and 129Xe MRI ventilation after a single benralizumab dose","volume":"162","author":"McIntosh","year":"2022","journal-title":"Chest"},{"key":"10.1016\/j.rmr.2026.06.003_bib0220","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.chest.2023.02.009","article-title":"CT mucus score and 129Xe MRI ventilation defects after 2.5\u00a0years\u2019 anti-IL-5R\u03b1 in eosinophilic asthma","volume":"164","author":"McIntosh","year":"2023","journal-title":"Chest"},{"key":"10.1016\/j.rmr.2026.06.003_bib0225","doi-asserted-by":"crossref","first-page":"2400061","DOI":"10.1183\/13993003.00061-2024","article-title":"Revised ISHAM-ABPA working group clinical practice guidelines for diagnosing, classifying and treating allergic bronchopulmonary aspergillosis\/mycoses","volume":"63","author":"Agarwal","year":"2024","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmr.2026.06.003_bib0115","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1148\/radiol.2017162350","article-title":"Allergic bronchopulmonary aspergillosis in cystic fibrosis: MR imaging of airway mucus contrasts as a tool for diagnosis","volume":"285","author":"Dournes","year":"2017","journal-title":"Radiology"}],"container-title":["Revue des Maladies Respiratoires"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0761842526000410?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0761842526000410?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T11:22:00Z","timestamp":1786101720000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0761842526000410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":23,"alternative-id":["S0761842526000410"],"URL":"https:\/\/doi.org\/10.1016\/j.rmr.2026.06.003","relation":{},"ISSN":["0761-8425"],"issn-type":[{"value":"0761-8425","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Apport du scanner pour le ph\u00e9notypage de l\u2019asthme s\u00e9v\u00e8re","name":"articletitle","label":"Article Title"},{"value":"Revue des Maladies Respiratoires","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmr.2026.06.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 SPLF. Published by Elsevier Masson SAS. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}