{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T08:59:56Z","timestamp":1768294796652,"version":"3.49.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,3,3]],"date-time":"2023-03-03T00:00:00Z","timestamp":1677801600000},"content-version":"vor","delay-in-days":30,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012665","name":"Institute for Clinical Evaluative Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000152","name":"Canadian Hemophilia Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000152","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001350","name":"Ministry of Health -Singapore","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001350","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rpthjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research and Practice in Thrombosis and Haemostasis"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.rpth.2023.100104","type":"journal-article","created":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T02:24:14Z","timestamp":1678415054000},"page":"100104","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Identifying the effect of inherited bleeding disorders on the development of postpartum hemorrhage: a population-based, retrospective cohort study"],"prefix":"10.1016","volume":"7","author":[{"given":"Julia C.","family":"Hews-Girard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"Galica","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Goldie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"James","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joan E.","family":"Tranmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rpth.2023.100104_bib1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S1701-2163(15)30680-0","article-title":"Temporal trends in postpartum hemorrhage and severe postpartum hemorrhage in Canada from 2003 to 2010","volume":"36","author":"Mehrabadi","year":"2014","journal-title":"J\u00a0Obstet Gynaecol Can"},{"key":"10.1016\/j.rpth.2023.100104_bib2","doi-asserted-by":"crossref","first-page":"449.e1-7","DOI":"10.1016\/j.ajog.2013.07.007","article-title":"Incidence, risk factors, and temporal trends in severe postpartum hemorrhage","volume":"209","author":"Kramer","year":"2013","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.rpth.2023.100104_bib3","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1111\/j.1471-0528.2008.01859.x","article-title":"Prevalence and risk factors of severe obstetric haemorrhage","volume":"115","author":"Al-Zirqi","year":"2008","journal-title":"BJOG"},{"key":"10.1016\/j.rpth.2023.100104_bib4","first-page":"247","article-title":"A\u00a0national update on rates of postpartum haemorrhage and related interventions","volume":"18","author":"Ahmadzia","year":"2020","journal-title":"Blood Transfus"},{"key":"10.1016\/j.rpth.2023.100104_bib5","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s12884-016-1217-0","article-title":"Risk factors for severe postpartum hemorrhage: a case-control study","volume":"17","author":"Nyfl\u00f8t","year":"2017","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.rpth.2023.100104_bib6","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1186\/s12884-021-03818-1","article-title":"Prevalence and risk factors of severe postpartum hemorrhage: a retrospective cohort study","volume":"21","author":"Liu","year":"2021","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.rpth.2023.100104_bib7","doi-asserted-by":"crossref","first-page":"391","DOI":"10.5694\/j.1326-5377.2007.tb01308.x","article-title":"Postpartum haemorrhage occurrence and recurrence: a population-based study","volume":"187","author":"Ford","year":"2007","journal-title":"Med J Aust"},{"key":"10.1016\/j.rpth.2023.100104_bib8","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/hae.12635","article-title":"Primary postpartum haemorrhage in women with von Willebrand disease or carriership of haemophilia despite specialised care: a retrospective survey","volume":"21","author":"Stoof","year":"2015","journal-title":"Haemophilia"},{"key":"10.1016\/j.rpth.2023.100104_bib9","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.tmrv.2018.06.003","article-title":"Inherited bleeding disorders in the obstetric patient","volume":"32","author":"Bannow","year":"2018","journal-title":"Transfus Med Rev"},{"key":"10.1016\/j.rpth.2023.100104_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0164683","article-title":"Postpartum hemorrhage in women with von Willebrand disease \u2013 a retrospective observational study","volume":"11","author":"Govorov","year":"2016","journal-title":"PLOS ONE"},{"key":"10.1016\/j.rpth.2023.100104_bib11","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1111\/hae.13067","article-title":"Obstetric bleeding among women with inherited bleeding disorders: a retrospective study","volume":"22","author":"Hawke","year":"2016","journal-title":"Haemophilia"},{"key":"10.1016\/j.rpth.2023.100104_bib12","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1365-2516.2005.01108.x","article-title":"More than menorrhagia: a review of the obstetric and gynaecological manifestations of bleeding disorders","volume":"11","author":"James","year":"2005","journal-title":"Haemophilia"},{"key":"10.1016\/j.rpth.2023.100104_bib13","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1046\/j.1365-2516.2000.00447.x","article-title":"Gynaecological and obstetrical morbidity in women with type I von Willebrand disease: results of a patient survey","volume":"6","author":"Kouides","year":"2000","journal-title":"Haemophilia"},{"key":"10.1016\/j.rpth.2023.100104_bib14","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/j.1538-7836.2011.04372.x","article-title":"Gynecological and obstetrical manifestations of inherited bleeding disorders in women","volume":"9","author":"Peyvandi","year":"2011","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.rpth.2023.100104_bib15","doi-asserted-by":"crossref","first-page":"4666","DOI":"10.1182\/bloodadvances.2021004352","article-title":"Suboptimal iron deficiency screening in pregnancy and the impact of socioeconomic status in a high-resource setting","volume":"5","author":"Teichman","year":"2021","journal-title":"Blood Adv"},{"key":"10.1016\/j.rpth.2023.100104_bib16","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1111\/j.1538-7836.2007.02563.x","article-title":"Bleeding events and other complications during pregnancy and childbirth in women with von Willebrand disease","volume":"5","author":"James","year":"2007","journal-title":"J\u00a0Thrombosis Haemost"},{"key":"10.1016\/j.rpth.2023.100104_bib17","doi-asserted-by":"crossref","first-page":"e442","DOI":"10.1111\/hae.12739","article-title":"Postpartum haemorrhage in women with von Willebrand disease: an observational study of the Pennsylvania Health Care Cost Containment Council (PHC4) database","volume":"21","author":"Malec","year":"2015","journal-title":"Haemophilia"},{"key":"10.1016\/j.rpth.2023.100104_bib18","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1182\/blood-2021-149673","article-title":"Impact of inherited bleeding disorders on maternal bleeding and other pregnancy outcomes: a population-based cohort study","volume":"138","author":"Alam","year":"2021","journal-title":"Blood"},{"key":"10.1016\/j.rpth.2023.100104_bib19","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1111\/hae.14594","article-title":"Determining the incidence of postpartum haemorrhage among Ontario women with and without inherited bleeding disorders: a population-based cohort study","volume":"28","author":"Hews-Girard","year":"2022","journal-title":"Haemophilia"},{"key":"10.1016\/j.rpth.2023.100104_bib20","unstructured":"Data ICES. Data Dictionary 2021, https:\/\/datadictionary.ices.on.ca\/Applications\/DataDictionary\/Default.aspx."},{"key":"10.1016\/j.rpth.2023.100104_bib21","series-title":"Primary Care in Ontario ICES Atlas Toronto: Institute for Clinical Evaluative Sciences","first-page":"15","article-title":"Care of women during pregnancy and childbirth","author":"Maaten","year":"2006"},{"key":"10.1016\/j.rpth.2023.100104_bib22","first-page":"927","article-title":"Secondary postpartum haemorrhage: incidence, morbidity and current management","volume":"108","author":"Hoveyda","year":"2001","journal-title":"BJOG"},{"key":"10.1016\/j.rpth.2023.100104_bib24","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1111\/j.1475-6773.2007.00822.x","article-title":"Assessing validity of ICD-9-CM and ICD-10 administrative data in recording clinical conditions in a unique dually coded database","volume":"43","author":"Quan","year":"2008","journal-title":"Health Serv Res"},{"key":"10.1016\/j.rpth.2023.100104_bib25","doi-asserted-by":"crossref","first-page":"96","DOI":"10.24095\/hpcdp.29.3.01","article-title":"Validation of perinatal data in the Discharge Abstract Database of the Canadian Institute for Health Information","volume":"29","author":"Joseph","year":"2009","journal-title":"Chronic Dis Can"},{"key":"10.1016\/j.rpth.2023.100104_bib26","series-title":"Ontario marginalization index","author":"Matheson","year":"2016"},{"key":"10.1016\/j.rpth.2023.100104_bib28","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1111\/bjh.16221","article-title":"UK guidelines on the management of iron deficiency in pregnancy","volume":"188","author":"Pavord","year":"2020","journal-title":"Br J Haematol"},{"key":"10.1016\/j.rpth.2023.100104_bib29","doi-asserted-by":"crossref","first-page":"3083","DOI":"10.1002\/sim.3697","article-title":"Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples","volume":"28","author":"Austin","year":"2009","journal-title":"Stat Med"},{"key":"10.1016\/j.rpth.2023.100104_bib30","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1093\/aje\/kwh090","article-title":"A\u00a0modified Poisson regression approach to prospective studies with binary data","volume":"159","author":"Zou","year":"2004","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.rpth.2023.100104_bib31","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1213\/ANE.0b013e3181d74898","article-title":"The epidemiology of postpartum hemorrhage in a large, nationwide sample of deliveries","volume":"110","author":"Bateman","year":"2010","journal-title":"Anesth Analg"},{"key":"10.1016\/j.rpth.2023.100104_bib32","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s12874-016-0135-1","article-title":"On the use of propensity scores in case of rare exposure","volume":"16","author":"Hajage","year":"2016","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.rpth.2023.100104_bib33","series-title":"The SAGE encyclopedia of communication research methods","author":"Allen","year":"2017"},{"key":"10.1016\/j.rpth.2023.100104_bib34","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1037\/0022-3514.51.6.1173","article-title":"The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations","volume":"51","author":"Baron","year":"1986","journal-title":"J\u00a0Pers Soc Psychol"},{"key":"10.1016\/j.rpth.2023.100104_bib35","doi-asserted-by":"crossref","first-page":"879","DOI":"10.3758\/BRM.40.3.879","article-title":"Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models","volume":"40","author":"Preacher","year":"2008","journal-title":"Behav Res Methods"},{"key":"10.1016\/j.rpth.2023.100104_bib36","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1093\/aje\/kwq332","article-title":"Odds ratios for mediation analysis for a dichotomous outcome","volume":"172","author":"Vanderweele","year":"2010","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.rpth.2023.100104_bib37","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1093\/aje\/kwr525","article-title":"A\u00a0simple unified approach for estimating natural direct and indirect effects","volume":"176","author":"Lange","year":"2012","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.rpth.2023.100104_bib38","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/hae.12568","article-title":"Postpartum von Willebrand factor levels in women with and without von Willebrand disease and implications for prophylaxis","volume":"21","author":"James","year":"2015","journal-title":"Haemophilia"},{"key":"10.1016\/j.rpth.2023.100104_bib39","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1111\/j.1471-0528.1997.tb12024.x","article-title":"The obstetric experience of carriers of haemophilia","volume":"104","author":"Kadir","year":"1997","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.rpth.2023.100104_bib40","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1111\/j.1365-2516.2012.02750.x","article-title":"Assessment of von Willebrand disease as a risk factor for primary postpartum haemorrhage","volume":"18","author":"Chee","year":"2012","journal-title":"Haemophilia"},{"key":"10.1016\/j.rpth.2023.100104_bib41","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/rth2.12468","article-title":"Sexism in the management of bleeding disorders","volume":"5","author":"Weyand","year":"2021","journal-title":"Res Pract Thromb Haemost"},{"key":"10.1016\/j.rpth.2023.100104_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2021.100726","article-title":"Major differences in clinical presentation, diagnosis and management of men and women with autosomal inherited bleeding disorders","volume":"32","author":"Atiq","year":"2021","journal-title":"EClinicalMedicine"},{"key":"10.1016\/j.rpth.2023.100104_bib43","doi-asserted-by":"crossref","first-page":"229.e1-8","DOI":"10.1016\/j.ajog.2013.10.872","article-title":"Patterns of recurrence of postpartum hemorrhage in a large population-based cohort","volume":"210","author":"Oberg","year":"2014","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.rpth.2023.100104_bib44","first-page":"e193","article-title":"Management of inherited bleeding disorders in pregnancy. Green-top Guideline No. 71","volume":"124","author":"Pavord","year":"2017","journal-title":"BJOG"},{"key":"10.1016\/j.rpth.2023.100104_bib45","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1182\/blood-2019-127602","article-title":"Prevalence of iron deficiency and iron deficiency anemia during pregnancy: a single centre Canadian study","volume":"134","author":"Tang","year":"2019","journal-title":"Blood"},{"key":"10.1016\/j.rpth.2023.100104_bib46","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/ejcn.2013.241","article-title":"Relationship between socioeconomic status and anemia prevalence in adolescent girls based on the fourth and fifth Korea National Health and Nutrition Examination Surveys","volume":"68","author":"Kim","year":"2014","journal-title":"Eur J Clin Nutr"}],"container-title":["Research and Practice in Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2475037923000730?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2475037923000730?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:26:33Z","timestamp":1762863993000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2475037923000730"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":44,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["S2475037923000730"],"URL":"https:\/\/doi.org\/10.1016\/j.rpth.2023.100104","relation":{},"ISSN":["2475-0379"],"issn-type":[{"value":"2475-0379","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identifying the effect of inherited bleeding disorders on the development of postpartum hemorrhage: a population-based, retrospective cohort study","name":"articletitle","label":"Article Title"},{"value":"Research and Practice in Thrombosis and Haemostasis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rpth.2023.100104","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Inc. on behalf of International Society on Thrombosis and Haemostasis.","name":"copyright","label":"Copyright"}],"article-number":"100104"}}