{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T01:29:11Z","timestamp":1772846951127,"version":"3.50.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["rpthjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research and Practice in Thrombosis and Haemostasis"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.rpth.2024.102638","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T17:17:01Z","timestamp":1732900621000},"page":"102638","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Type of D-dimer assay determines the diagnostic yield of computed tomography in patients suspected for pulmonary embolism"],"prefix":"10.1016","volume":"9","author":[{"given":"Jorn L.J.C.","family":"Assmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriaan J.","family":"van Gammeren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinier A.","family":"Sprenger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saskia","family":"de Wit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huib","family":"Ceelie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank W.G.","family":"Leebeek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0983-7532","authenticated-orcid":false,"given":"Mark W.M.","family":"Schellings","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rpth.2024.102638_bib1","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.jacc.2015.11.061","article-title":"Management of pulmonary embolism: an update","volume":"67","author":"Konstantinides","year":"2016","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.rpth.2024.102638_bib2","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1160\/TH07-05-0321","article-title":"Further validation and simplification of the Wells clinical decision rule in pulmonary embolism","volume":"99","author":"Gibson","year":"2008","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.rpth.2024.102638_bib3","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0140-6736(17)30885-1","article-title":"Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study","volume":"390","author":"van der Hulle","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.rpth.2024.102638_bib4","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1002\/ajh.25482","article-title":"The D-dimer assay","volume":"94","author":"Johnson","year":"2019","journal-title":"Am J Hematol"},{"key":"10.1016\/j.rpth.2024.102638_bib5","doi-asserted-by":"crossref","first-page":"102335","DOI":"10.1016\/j.rpth.2024.102335","article-title":"D-dimer diagnostics: can I use any D-dimer assay? Bridging the knowledge-to-action gap","volume":"8","author":"Selby","year":"2024","journal-title":"Res Pract Thromb Haemost"},{"key":"10.1016\/j.rpth.2024.102638_bib6","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1056\/NEJMoa1813865","article-title":"Pregnancy-adapted YEARS algorithm for diagnosis of suspected pulmonary embolism","volume":"380","author":"Van Der Pol","year":"2019","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.rpth.2024.102638_bib7","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1001\/jama.2014.2135","article-title":"Age-adjusted D-dimer cutoff levels to rule out\u00a0pulmonary embolism: the ADJUST-PE study","volume":"311","author":"Righini","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.rpth.2024.102638_bib8","doi-asserted-by":"crossref","first-page":"e016784","DOI":"10.1161\/JAHA.120.016784","article-title":"Time trends in pulmonary embolism mortality rates in the United States, 1999 to 2018","volume":"9","author":"Martin","year":"2020","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.rpth.2024.102638_bib9","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1055\/s-2000-13218","article-title":"Performance of semiquantitative and quantitative D-dimer assays in the ECAT external quality assessment program","volume":"26","author":"de Maat","year":"2000","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.rpth.2024.102638_bib10","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.thromres.2021.02.003","article-title":"Diagnostic accuracy of four different D-dimer assays: a post-hoc analysis of the YEARS study","volume":"201","author":"Hamer","year":"2021","journal-title":"Thromb Res"},{"key":"10.1016\/j.rpth.2024.102638_bib11","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s13244-014-0325-5","article-title":"Diagnostic yield of CT thorax angiography in patients suspected of pulmonary embolism: independent predictors and protocol adherence","volume":"5","author":"Walen","year":"2014","journal-title":"Insights Imaging"},{"key":"10.1016\/j.rpth.2024.102638_bib12","doi-asserted-by":"crossref","first-page":"V225","DOI":"10.1016\/S0049-3848(01)00326-7","article-title":"Diagnosis of pulmonary embolism","volume":"103","author":"Rodger","year":"2001","journal-title":"Thromb Res"},{"key":"10.1016\/j.rpth.2024.102638_bib13","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1056\/NEJMoa1909159","article-title":"Diagnosis of pulmonary embolism with D-dimer adjusted to clinical probability","volume":"381","author":"Kearon","year":"2019","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.rpth.2024.102638_bib14","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1111\/jth.13972","article-title":"The YEARS algorithm for suspected pulmonary embolism: shorter visit time and reduced costs at the emergency department","volume":"16","author":"van der Pol","year":"2018","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.rpth.2024.102638_bib15","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1160\/TH08-07-0444","article-title":"Validity and clinical utility of the simplified Wells rule for assessing clinical probability for the exclusion of pulmonary embolism","volume":"101","author":"Douma","year":"2009","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.rpth.2024.102638_bib16","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1056\/NEJMra072149","article-title":"Computed tomograph--an increasing source of radiation exposure","volume":"357","author":"Brenner","year":"2007","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.rpth.2024.102638_bib17","first-page":"5","article-title":"Trends in use and yield of chest computed tomography with angiography for diagnosis of pulmonary embolism in a Connecticut hospital emergency department","volume":"74","author":"Weir","year":"2010","journal-title":"Conn Med"},{"key":"10.1016\/j.rpth.2024.102638_bib18","doi-asserted-by":"crossref","first-page":"471","DOI":"10.2214\/AJR.07.2552","article-title":"CT angiography in the evaluation of acute pulmonary embolus","volume":"191","author":"Costantino","year":"2008","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.rpth.2024.102638_bib19","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.annemergmed.2010.09.018","article-title":"Effectiveness and acceptability of a computerized decision support system using modified Wells criteria for evaluation of suspected pulmonary embolism","volume":"57","author":"Drescher","year":"2011","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.rpth.2024.102638_bib20","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.annemergmed.2015.11.005","article-title":"The impact of clinical decision rules on computed tomography use and yield for pulmonary embolism: a systematic review and meta-analysis","volume":"67","author":"Wang","year":"2016","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.rpth.2024.102638_bib21","doi-asserted-by":"crossref","first-page":"e002119","DOI":"10.1136\/bmjoq-2022-002119","article-title":"Implementation of the YEARS algorithm to optimise pulmonary embolism diagnostic workup in the emergency department","volume":"12","author":"Duffy","year":"2023","journal-title":"BMJ Open Qual"},{"key":"10.1016\/j.rpth.2024.102638_bib22","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1055\/s-0042-1757634","article-title":"COVID-19-associated pulmonary embolism: review of the pathophysiology, epidemiology, prevention, diagnosis, and treatment","volume":"49","author":"Ortega-Paz","year":"2023","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.rpth.2024.102638_bib23","article-title":"Comparative evaluation of different D-dimer assays for exclusion of venous thromboembolism in a clinical routine setting","volume":"32","author":"Roggenbuck","year":"2008","journal-title":"LaboratoriumsMedizin"},{"key":"10.1016\/j.rpth.2024.102638_bib24","doi-asserted-by":"crossref","first-page":"100147","DOI":"10.1016\/j.tru.2023.100147","article-title":"Evaluation of the diagnostic performance of three D-dimer assays in patients with suspected deep vein thrombosis: STA-Liatest D-Di plus, Tina-quant D-dimer Gen. 2, and INNOVANCE D-dimer","volume":"13","author":"Tonne","year":"2023","journal-title":"Thromb Update"},{"key":"10.1016\/j.rpth.2024.102638_bib25","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1002\/ajh.21455","article-title":"An age-adapted approach for the use of D-dimers in the exclusion of deep venous thrombosis","volume":"84","author":"Haas","year":"2009","journal-title":"Am J Hematol"},{"key":"10.1016\/j.rpth.2024.102638_bib26","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1111\/jth.13994","article-title":"Age-adjusted D-dimer cut-off leads to more efficient diagnosis of venous thromboembolism in the emergency department: a comparison of four assays","volume":"16","author":"Farm","year":"2018","journal-title":"J\u00a0Thromb Haemost"}],"container-title":["Research and Practice in Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2475037924003339?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2475037924003339?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T23:49:42Z","timestamp":1751932182000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2475037924003339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S2475037924003339"],"URL":"https:\/\/doi.org\/10.1016\/j.rpth.2024.102638","relation":{},"ISSN":["2475-0379"],"issn-type":[{"value":"2475-0379","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Type of D-dimer assay determines the diagnostic yield of computed tomography in patients suspected for pulmonary embolism","name":"articletitle","label":"Article Title"},{"value":"Research and Practice in Thrombosis and Haemostasis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rpth.2024.102638","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc. on behalf of International Society on Thrombosis and Haemostasis.","name":"copyright","label":"Copyright"}],"article-number":"102638"}}