{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T19:21:06Z","timestamp":1761938466358,"version":"build-2065373602"},"reference-count":22,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1016\/j.rvsc.2005.03.001","type":"journal-article","created":{"date-parts":[[2005,7,30]],"date-time":"2005-07-30T08:39:43Z","timestamp":1122712783000},"page":"197-201","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Effect of antineoplastic drugs on the expression of Bcl-2 and Bcl-xL genes in the feline T-cell leukemia cell line"],"prefix":"10.1016","volume":"79","author":[{"given":"Junichi","family":"Sano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunpei","family":"Nagafuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junpei","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Oguma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Kano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsuhiko","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rvsc.2005.03.001_bib1","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1002\/ijc.2910600622","article-title":"Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis","volume":"60","author":"Bargou","year":"1995","journal-title":"International Journal of Cancer"},{"key":"10.1016\/j.rvsc.2005.03.001_bib2","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1016\/0006-2952(90)90733-2","article-title":"Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia","volume":"40","author":"Barry","year":"1990","journal-title":"Biochemical Pharmacology"},{"key":"10.1016\/j.rvsc.2005.03.001_bib3","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0092-8674(86)90362-4","article-title":"Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2\/immunoglobulin transcript resulting from the t(14;18) translocation","volume":"47","author":"Cleary","year":"1986","journal-title":"Cell."},{"key":"10.1016\/j.rvsc.2005.03.001_bib4","first-page":"2576","article-title":"Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis","volume":"55","author":"Dole","year":"1995","journal-title":"Cancer Research"},{"key":"10.1016\/j.rvsc.2005.03.001_bib5","first-page":"275","article-title":"Activation of programmed cell death by anticancer agents: cisplatin as a model system","volume":"2","author":"Eastman","year":"1990","journal-title":"Cancer Cells"},{"key":"10.1016\/j.rvsc.2005.03.001_bib6","doi-asserted-by":"crossref","first-page":"6627","DOI":"10.1038\/sj.onc.1204087","article-title":"Bcl-2 family proteins as targets for anticancer drug design","volume":"19","author":"Huang","year":"2000","journal-title":"Oncogene"},{"key":"10.1016\/j.rvsc.2005.03.001_bib7","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1002\/1097-0142(19940415)73:8<2013::AID-CNCR2820730802>3.0.CO;2-J","article-title":"Apoptosis. Its significance in cancer and cancer therapy","volume":"73","author":"Kerr","year":"1994","journal-title":"Cancer"},{"key":"10.1016\/j.rvsc.2005.03.001_bib8","first-page":"2422","article-title":"Elevated expression of Bcl-X and reduced Bak in primary colorectal adenocarcinomas","volume":"56","author":"Krajewska","year":"1996","journal-title":"Cancer Research"},{"key":"10.1016\/j.rvsc.2005.03.001_bib9","first-page":"647","article-title":"Regulation of Bcl-2, Bcl-xL and bax in the control of apoptosis by hematopoietic cytokines and dexamethasone","volume":"6","author":"Lotem","year":"1995","journal-title":"Cell Growth and Differentiation"},{"key":"10.1016\/j.rvsc.2005.03.001_bib10","first-page":"658","article-title":"Apoptosis: its role in the progression of and chemotherapy for carcinoma","volume":"18","author":"Meterissian","year":"1997","journal-title":"Journal of the American College of Surgeons"},{"key":"10.1016\/j.rvsc.2005.03.001_bib11","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1182\/blood.V86.5.1903.bloodjournal8651903","article-title":"Expression of bcl-xL can confer a multidrug resistance phenotype","volume":"86","author":"Minn","year":"1995","journal-title":"Blood"},{"key":"10.1016\/j.rvsc.2005.03.001_bib12","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/0042-6822(89)90172-4","article-title":"Molecular cloning of a feline leukemia provirus integrated adjacent to the c-myc gene in a feline T-cell leukemia cell line and the unique structure of its long terminal repeat","volume":"169","author":"Miura","year":"1989","journal-title":"Virology"},{"key":"10.1016\/j.rvsc.2005.03.001_bib13","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/ijc.2910400422","article-title":"Structural abnormality and over-expression of the myc gene in feline leukemias","volume":"40","author":"Miura","year":"1987","journal-title":"International Journal of Cancer"},{"key":"10.1016\/j.rvsc.2005.03.001_bib14","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1182\/blood.V81.1.151.151","article-title":"Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line","volume":"81","author":"Miyashita","year":"1993","journal-title":"Blood"},{"key":"10.1016\/j.rvsc.2005.03.001_bib15","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1200\/JCO.1988.6.3.517","article-title":"Pharmacokinetics and metabolism of epidoxorubicin and doxorubicin in humans","volume":"6","author":"Mross","year":"1988","journal-title":"Journal of Clinical Oncology"},{"key":"10.1016\/j.rvsc.2005.03.001_bib16","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/mpo.2950100202","article-title":"The comparative clinical pharmacology and pharmacokinetics of vindesine, vincristine, and vinblastine in human patients with cancer","volume":"10","author":"Nelson","year":"1982","journal-title":"Medical and Pediatric Oncology"},{"key":"10.1016\/j.rvsc.2005.03.001_bib17","series-title":"Small animal internal medicine","first-page":"1123","article-title":"Lymphoma in the cat and dog","author":"Nelson","year":"1998"},{"key":"10.1016\/j.rvsc.2005.03.001_bib18","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0165-2427(00)00196-3","article-title":"In vitro study of neutrophil apoptosis in dogs","volume":"76","author":"Oguma","year":"2000","journal-title":"Veterinary Immunology and Immunopathology"},{"key":"10.1016\/j.rvsc.2005.03.001_bib19","first-page":"654","article-title":"Studies on clinical effects of steroid. 2. Absorption of prednisolone after retrobulbar injection in to the circulation","volume":"12","author":"Seo","year":"1961","journal-title":"Nippon Ganka Kiyo"},{"key":"10.1016\/j.rvsc.2005.03.001_bib20","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/(SICI)1096-8652(199604)51:4<261::AID-AJH2>3.0.CO;2-U","article-title":"In vitro culture with prednisolone increases Bcl-2 protein expression in adult acute lymphoblastic leukemia cells","volume":"51","author":"Tosi","year":"1996","journal-title":"American Journal of Hematology"},{"key":"10.1016\/j.rvsc.2005.03.001_bib21","doi-asserted-by":"crossref","first-page":"5214","DOI":"10.1073\/pnas.83.14.5214","article-title":"Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma","volume":"83","author":"Tsujimoto","year":"1986","journal-title":"Proceedings of National Academic Sciences USA"},{"key":"10.1016\/j.rvsc.2005.03.001_bib22","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1182\/blood.V88.5.1805.1805","article-title":"Upregulated expression of BCL-2 in multiple myeloma cells induced by exposure to doxorubicin, etoposide, and hydrogen peroxide","volume":"88","author":"Tu","year":"1996","journal-title":"Blood"}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528805000457?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528805000457?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T03:32:42Z","timestamp":1758511962000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034528805000457"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["S0034528805000457"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2005.03.001","relation":{},"ISSN":["0034-5288"],"issn-type":[{"type":"print","value":"0034-5288"}],"subject":[],"published":{"date-parts":[[2005,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of antineoplastic drugs on the expression of Bcl-2 and Bcl-xL genes in the feline T-cell leukemia cell line","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2005.03.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}