{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:18:58Z","timestamp":1761488338901,"version":"3.44.0"},"reference-count":54,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2010,4]]},"DOI":"10.1016\/j.rvsc.2009.10.001","type":"journal-article","created":{"date-parts":[[2009,11,3]],"date-time":"2009-11-03T05:17:05Z","timestamp":1257225425000},"page":"273-278","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Growth hormones therapy in immune response against Trypanosoma cruzi"],"prefix":"10.1016","volume":"88","author":[{"given":"Eduardo Os\u00f3rio","family":"Frare","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabricia Helena","family":"Santello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leony Cristina","family":"Caetano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerri C.","family":"Caldeira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00edriam Paula Alonso","family":"Toldo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Jos\u00e9 Cl\u00f3vis do","family":"Prado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rvsc.2009.10.001_bib1","doi-asserted-by":"crossref","first-page":"3955","DOI":"10.4049\/jimmunol.155.8.3955","article-title":"Cytokine and nitric oxide regulation of the immunosuppression in Trypanosoma cruzi infection","volume":"155","author":"Abrahamsohn","year":"1995","journal-title":"J. Immunol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib2","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1006\/expr.1996.0109","article-title":"Trypanosoma cruzi: IL-10, TNF, IFN-\u03b3 and IL-12 regulate innate and acquired immunity to infection","volume":"84","author":"Abrahamsohn","year":"1996","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib3","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1016\/S0002-9440(10)64094-1","article-title":"Modulation of chemokine production and inflammatory responses in interferon-gamma- and tumor necrosis factor-R1-deficient mice during Trypanosoma cruzi infection","volume":"158","author":"Aliberti","year":"2001","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib4","first-page":"984","article-title":"Differential expression of surface membrane growth hormone receptor on human peripheral blood lymphocytes detected by dual fluorochrome flow cytometry","volume":"79","author":"Badolato","year":"1994","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.rvsc.2009.10.001_bib5","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1210\/endo-128-3-1459","article-title":"Growth hormone (GH) receptors in clonal osteoblast-like cells mediate a mitogenic response to GH","volume":"128","author":"Barnard","year":"1991","journal-title":"Endocrinology"},{"key":"10.1016\/j.rvsc.2009.10.001_bib6","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1210\/edrv-17-1-64","article-title":"Immune\u2013neuro\u2013endocrine interactions: facts and hypotheses","volume":"17","author":"Besedovsky","year":"1996","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.rvsc.2009.10.001_bib7","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/0167-5699(94)90205-4","article-title":"The syntax of immune\u2013neuroendocrine communication","volume":"15","author":"Blalock","year":"1994","journal-title":"Immunol. Today"},{"key":"10.1016\/j.rvsc.2009.10.001_bib8","first-page":"389","article-title":"Therapeutic activity and criterion of cure in mice experimentally infected with Trypanosoma cruzi","volume":"4","author":"Brener","year":"1962","journal-title":"Rev. Inst. Med. Trop. S\u00e3o Paulo"},{"key":"10.1016\/j.rvsc.2009.10.001_bib9","series-title":"Modern Parasite Biology \u2013 Cellular, Immunological and Molecular Aspects.","first-page":"247","article-title":"Immunology of Chagas\u2019 disease","author":"Brener","year":"1982"},{"key":"10.1016\/j.rvsc.2009.10.001_bib10","doi-asserted-by":"crossref","first-page":"3203","DOI":"10.1210\/endo.140.7.6854","article-title":"Growth hormone (GH) and prolactin receptors in human peripheral blood mononuclear cells: relation with age and GH-binding protein","volume":"140","author":"Bresson","year":"1999","journal-title":"Endocrinology"},{"year":"2000","series-title":"Immune Response to Trypanosoma cruzi: Control of Infection and Pathogenesis of Chagas\u2019 Disease","author":"Buckner","key":"10.1016\/j.rvsc.2009.10.001_bib11"},{"key":"10.1016\/j.rvsc.2009.10.001_bib12","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1007\/s10620-006-9186-1","article-title":"Influence of Trypanosoma cruzi chronic infection in the depletion of esophageal neurons in Calomys callosus","volume":"51","author":"Caetano","year":"2006","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.rvsc.2009.10.001_bib13","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1128\/iai.64.1.128-134.1996","article-title":"Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells","volume":"64","author":"Cardillo","year":"1996","journal-title":"Infect. Immun."},{"key":"10.1016\/j.rvsc.2009.10.001_bib14","doi-asserted-by":"crossref","first-page":"2960","DOI":"10.1128\/IAI.66.6.2960-2968.1998","article-title":"Trypanosoma cruzi infection in tumor necrosis factor receptor p55-deficient mice","volume":"66","author":"Casta\u00f1os-Velez","year":"1998","journal-title":"Infect. Immun."},{"key":"10.1016\/j.rvsc.2009.10.001_bib15","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1590\/S0037-86821985000400003","article-title":"Estudo parasitol\u00f3gico e an\u00e1tomo-patol\u00f3gico da fase aguda da doen\u00e7a de Chagas em c\u00e3es inoculados com duas diferentes cepas do Trypanosoma cruzi","volume":"18","author":"Castro","year":"1985","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"10.1016\/j.rvsc.2009.10.001_bib16","first-page":"1919","article-title":"Bone loss is correlated to the severity of growth hormone deficiency in adult patients with hypopituitarism","volume":"84","author":"Colao","year":"1999","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.rvsc.2009.10.001_bib17","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1080\/08916930500485002","article-title":"Induction of cardiac autoimmunity in Chagas heart disease: a case for molecular mimicry","volume":"39","author":"Cunha-Neto","year":"2006","journal-title":"Autoimmunity"},{"key":"10.1016\/j.rvsc.2009.10.001_bib18","first-page":"349","article-title":"Trypanosoma cruzi: maintenance of parasite-specific T cell responses in lymph nodes during the acute phase of infection","volume":"70","author":"Curotto-De-Lafaille","year":"1990","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib19","doi-asserted-by":"crossref","first-page":"3837","DOI":"10.1210\/endo.139.9.6199","article-title":"Growth hormone and its receptor are expressed in human thymic cells","volume":"139","author":"de Mello-Coelho","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.rvsc.2009.10.001_bib20","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S1286-4579(01)01461-7","article-title":"Prevalence of CD8(+)alpha beta T cells in Trypanosoma cruzi-elicited myocarditis is associated with acquisition of CD62L(Low)LFA-1(High)VLA-4(High) activation phenotype and expression of IFN-gamma-inducible adhesion and chemoattractant molecules","volume":"3","author":"dos Santos","year":"2001","journal-title":"Microbes Infect."},{"key":"10.1016\/j.rvsc.2009.10.001_bib21","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1002\/eji.1830221006","article-title":"The microbicidal activity of interferon-gamma treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-\u03b1","volume":"22","author":"Gazzinelli","year":"1992","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib22","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1210\/jcem-71-2-464","article-title":"Growth hormone mediates the growth of T-lymphoblast cell lines via locally generated insulin-like growth factor-I","volume":"71","author":"Geffner","year":"1990","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.rvsc.2009.10.001_bib23","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/0014-4894(91)90085-B","article-title":"Trypanosoma cruzi: cytokine effects on macrophage trypanocidal activity","volume":"72","author":"Golden","year":"1991","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib24","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0003-2697(82)90118-X","article-title":"Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids","volume":"126","author":"Green","year":"1982","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.rvsc.2009.10.001_bib25","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/0006-291X(90)92334-V","article-title":"Immunoreactive growth hormone (GH) secretion by human lymphocytes: augmented release by exogenous GH","volume":"168","author":"Hattori","year":"1990","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.rvsc.2009.10.001_bib26","first-page":"669","article-title":"Reduced bone mineral density in patients with adult onset growth hormone deficiency","volume":"78","author":"Holmes","year":"1994","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.rvsc.2009.10.001_bib27","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1128\/IAI.66.3.1208-1215.1998","article-title":"Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in alpha interferon receptor or inducible nitric oxide synthase","volume":"66","author":"Holscher","year":"1998","journal-title":"Infect. Immunol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib28","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1007\/BF00711549","article-title":"Immunoreactive growth hormone production by human lymphocyte cell lines","volume":"12","author":"Kao","year":"1992","journal-title":"Cell Mol. Neurobiol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib29","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1007\/BF00298723","article-title":"Growth hormone stimulates proliferation and differentiation of normal human osteoblast-like cells in vitro","volume":"52","author":"Kassem","year":"1993","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.rvsc.2009.10.001_bib30","first-page":"118","article-title":"Bone mineral status in growth hormone deficient males with isolated and multiple pituitary deficiencies of childhood onset","volume":"74","author":"Kaufman","year":"1992","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.rvsc.2009.10.001_bib31","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1749-6632.1990.tb40471.x","article-title":"The role of growth hormone in modulation of the immune response","volume":"594","author":"Kelley","year":"1990","journal-title":"Ann. NY Acad. Sci."},{"key":"10.1016\/j.rvsc.2009.10.001_bib32","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.pt.2005.08.013","article-title":"Where do we stand on the autoimmunity hypothesis of Chagas disease?","volume":"21","author":"Kierszenbaum","year":"2005","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib33","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1530\/eje.0.1380482","article-title":"Hormonal control of programmed cell death\/apoptosis","volume":"138","author":"Kiess","year":"1998","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib34","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1677\/joe.0.1490351","article-title":"IGF-I potentiates interleukin-2 production in human peripheral T cells","volume":"149","author":"Kooijman","year":"1996","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib35","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1210\/endo.132.2.7678796","article-title":"Growth hormone expression in human Burkitt lymphoma serum-free Ramos cell line","volume":"132","author":"Lytras","year":"1993","journal-title":"Endocrinology"},{"key":"10.1016\/j.rvsc.2009.10.001_bib36","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/0092-8674(82)90440-8","article-title":"Growth hormone and the adipose conversion of 3T3 cells","volume":"29","author":"Morikawa","year":"1982","journal-title":"Cell"},{"key":"10.1016\/j.rvsc.2009.10.001_bib37","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/eji.1830220203","article-title":"Synergism between tumor necrosis factor a and interferon g on macrophage activation against intracellular Trypanosoma cruzi through a nitric oxide-dependent mechanism","volume":"22","author":"Mu\u00f1oz Fernandez","year":"1992","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib38","doi-asserted-by":"crossref","first-page":"3429","DOI":"10.1073\/pnas.81.11.3429","article-title":"Growth hormone promotes the differentiation of myoblasts and preadipocytes generated by azacytidine treatment of 10T1\/2 cells","volume":"81","author":"Nixon","year":"1984","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.rvsc.2009.10.001_bib39","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1210\/endo.138.5.5108","article-title":"Growth hormone stimulates the proliferation of activated mouse T lymphocytes","volume":"138","author":"Postel-Vinay","year":"1997","journal-title":"Endocrinology"},{"key":"10.1016\/j.rvsc.2009.10.001_bib40","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1007\/s004360050639","article-title":"Influence of male gonodal hormones on the parasitemia and humoral response of male Calomys callosus infected with the Y strain of Trypanosoma cruzi","volume":"85","author":"Prado","year":"1999","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.rvsc.2009.10.001_bib41","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/0014-4894(78)90059-0","article-title":"Trypanosoma cruzi: immunosuppressed response to different antigens induced in the infected mouse","volume":"45","author":"Ramos","year":"1978","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib42","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.cellimm.2007.12.003","article-title":"Neuroendocrine hormones such as growth hormone and prolactin are integral members of the immunological cytokine network","volume":"252","author":"Redelman","year":"2008","journal-title":"Cell Immunol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib43","doi-asserted-by":"crossref","first-page":"4342","DOI":"10.4049\/jimmunol.140.12.4342","article-title":"In vivo administration of recombinant IFN-g induces macrophage activation, and prevents acute disease, immune suppression, and death in experimental Trypanosoma cruzi infections","volume":"140","author":"Reed","year":"1988","journal-title":"J. Immunol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib44","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/j.1348-0421.1995.tb02201.x","article-title":"Experimental Trypanosoma cruzi infection in the rat. Response to systemic treatment with recombinant rat interferon gamma","volume":"39","author":"Revelli","year":"1995","journal-title":"Microbiol. Immunol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib45","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.1600-079X.2007.00427.x","article-title":"Melatonin treatment reduces the severity of experimental Trypanosoma cruzi infection","volume":"42","author":"Santello","year":"2007","journal-title":"J. Pineal. Res."},{"key":"10.1016\/j.rvsc.2009.10.001_bib46","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.exppara.2005.03.009","article-title":"Trypanosoma cruzi: effects of repetitive stress during the development of experimental infection","volume":"110","author":"Santos","year":"2005","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib47","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.vetpar.2006.08.038","article-title":"Haematological and histopathological findings after ovariectomy in Trypanosoma cruzi infected mice","volume":"143","author":"Santos","year":"2007","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib48","first-page":"191","article-title":"Sobre uma cepa de Trypanosoma cruzi altamente virulenta para o camundongo branco","volume":"20","author":"Silva","year":"1953","journal-title":"Folia Clin. Biol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib49","doi-asserted-by":"crossref","first-page":"4862","DOI":"10.1128\/iai.63.12.4862-4867.1995","article-title":"Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages","volume":"63","author":"Silva","year":"1995","journal-title":"Infect. Immun."},{"key":"10.1016\/j.rvsc.2009.10.001_bib50","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S1286-4579(00)00388-9","article-title":"Kinetics of cytokine gene expression in experimental chagasic cardiomyopathy: tissue parasitism and endogenous IFN-gamma as important determinants of chemokine mRNA expression during infection with Trypanosoma cruzi","volume":"2","author":"Talvani","year":"2000","journal-title":"Microbes Infect."},{"key":"10.1016\/j.rvsc.2009.10.001_bib51","doi-asserted-by":"crossref","first-page":"3626","DOI":"10.4049\/jimmunol.146.10.3626","article-title":"Endogenous IFN-gamma is required for resistance to acute Trypanosoma cruzi infection in mice","volume":"146","author":"Torrico","year":"1991","journal-title":"J. Immunol."},{"key":"10.1016\/j.rvsc.2009.10.001_bib52","doi-asserted-by":"crossref","first-page":"5177","DOI":"10.1128\/iai.62.11.5177-5182.1994","article-title":"Nitric oxide is involved in the control of Trypanosoma cruzi induced parasitemia and directly kills parasite in vitro","volume":"62","author":"Vespa","year":"1994","journal-title":"Infect. Immun."},{"key":"10.1016\/j.rvsc.2009.10.001_bib53","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1038\/284512a0","article-title":"Growth hormone: deletions in the protein and introns in the gene","volume":"284","author":"Wallis","year":"1980","journal-title":"Nature"},{"key":"10.1016\/j.rvsc.2009.10.001_bib54","unstructured":"WHO \u2013 World Health Organization, 2002. Control of Chagas\u2019 Disease, WHO Technical Report Series 811, Geneva."}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528809002227?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528809002227?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T03:47:33Z","timestamp":1758512853000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034528809002227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4]]},"references-count":54,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["S0034528809002227"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2009.10.001","relation":{},"ISSN":["0034-5288"],"issn-type":[{"type":"print","value":"0034-5288"}],"subject":[],"published":{"date-parts":[[2010,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Growth hormones therapy in immune response against Trypanosoma cruzi","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2009.10.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}