{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T01:40:15Z","timestamp":1761961215544,"version":"build-2065373602"},"reference-count":48,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003381","name":"Minist\u00e9rio da Educa\u00e7\u00e3o e Ci\u00eancia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003381","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007273","name":"Comisi\u00f3n Interministerial de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["AGL2007-65,521-C02-01\/GAN","AGL2007-65,521-C02-02\/GAN","BES-2008-009883"],"award-info":[{"award-number":["AGL2007-65,521-C02-01\/GAN","AGL2007-65,521-C02-02\/GAN","BES-2008-009883"]}],"id":[{"id":"10.13039\/501100007273","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.rvsc.2010.07.019","type":"journal-article","created":{"date-parts":[[2010,8,31]],"date-time":"2010-08-31T06:58:16Z","timestamp":1283237896000},"page":"457-462","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Peripheral white blood cell counts throughout pregnancy in non-aborting Neospora caninum-seronegative and seropositive high-producing dairy cows in a Holstein Friesian herd"],"prefix":"10.1016","volume":"90","author":[{"given":"B.","family":"Serrano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Almer\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Garc\u00eda-Ispierto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.L.","family":"Y\u00e1niz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Abdelfattah-Hassan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"L\u00f3pez-Gatius","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rvsc.2010.07.019_b0005","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1046\/j.1365-3024.2003.00645.x","article-title":"Cytokine gene expression in dams and foetuses after experimental Neospora caninum infection of heifers at 110 days of gestation","volume":"25","author":"Almer\u00eda","year":"2003","journal-title":"Parasite Immunology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0010","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0378-4320(00)00117-2","article-title":"Neosporosis in cattle","volume":"60\u201361","author":"Anderson","year":"2000","journal-title":"Animal Reproduction Science"},{"key":"10.1016\/j.rvsc.2010.07.019_b0015","doi-asserted-by":"crossref","first-page":"6052","DOI":"10.4049\/jimmunol.171.11.6052","article-title":"Cross-talk in the innate immune system: neutrophils instruct recruitment and activation of dendritic cells during microbial infection","volume":"171","author":"Bennouna","year":"2003","journal-title":"Journal of Immunology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0020","doi-asserted-by":"crossref","first-page":"4898","DOI":"10.1128\/IAI.69.8.4898-4905.2001","article-title":"Neutrophil depletion during Toxoplasma gondii infection leads to impaired immunity and lethal systemic pathology","volume":"69","author":"Bliss","year":"2001","journal-title":"Infection and Immunity"},{"key":"10.1016\/j.rvsc.2010.07.019_b0025","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1095\/biolreprod.103.017590","article-title":"Effects of prostaglandin F2alpha and progesterone on the ability of bovine luteal cells to stimulate T lymphocyte proliferation","volume":"69","author":"Cannon","year":"2003","journal-title":"Biology of Reproduction"},{"key":"10.1016\/j.rvsc.2010.07.019_b0030","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0165-2427(94)05302-9","article-title":"Study of immunological dysfunction in periparturient Holstein cattle selected for high and average milk production","volume":"44","author":"Detilleux","year":"1995","journal-title":"Veterinary Immunology and Immunopathology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0035","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0093-691X(93)90278-D","article-title":"Assessment of fetal number, and fetal and placental viability throughout pregnancy in cattle","volume":"40","author":"Dobson","year":"1993","journal-title":"Theriogenology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0040","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1128\/CMR.00031-06","article-title":"Epidemiology and control of neosporosis and Neospora caninum","volume":"20","author":"Dubey","year":"2007","journal-title":"Clinical Microbiology Reviews"},{"key":"10.1016\/j.rvsc.2010.07.019_b0045","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/0093-691X(90)90644-9","article-title":"Partial characterization of the immunosupressive properties of pregnancy-specific protein B (PSPB)","volume":"33","author":"Dunbar","year":"1990","journal-title":"Theriogenology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0050","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.2527\/jas.2005-714","article-title":"Increased vascular endothelial growth factor and pregnancy-associated glycoproteins, but not insulin-like growth factor-I, in maternal blood of cows gestating twin fetuses","volume":"84","author":"Echternkamp","year":"2006","journal-title":"Journal of Animal Science"},{"key":"10.1016\/j.rvsc.2010.07.019_b0055","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1600-0897.2006.00446.x","article-title":"Trophoblast-macrophage interactions: a regulatory network for the protection of pregnancy","volume":"57","author":"Fest","year":"2007","journal-title":"American Journal of Reproductive Immunology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0060","doi-asserted-by":"crossref","first-page":"274","DOI":"10.3168\/jds.S0022-0302(07)72628-0","article-title":"Regulation of interferon-stimulated genes in peripheral blood leukocytes in pregnant and bred, nonpregnant dairy cows","volume":"90","author":"Gifford","year":"2007","journal-title":"Journal of Dairy Science"},{"key":"10.1016\/j.rvsc.2010.07.019_b0065","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.vetimm.2009.05.002","article-title":"Natural killer cell number and phenotype in bovine peripheral blood is influenced by age","volume":"132","author":"Graham","year":"2009","journal-title":"Veterinary Immunology and Immunopathology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0070","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0007-1935(17)46202-6","article-title":"Observations on the haematology of calves and various breeds of adult dairy cattle","volume":"113","author":"Greatorex","year":"1957","journal-title":"British Veterinary Journal"},{"key":"10.1016\/j.rvsc.2010.07.019_b0075","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0007-1935(17)45756-3","article-title":"Observations on the haematology of calves and various breeds of adult dairy cattle","volume":"113","author":"Greatorex","year":"1957","journal-title":"British Veterinary Journal"},{"key":"10.1016\/j.rvsc.2010.07.019_b0080","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0165-2427(99)00031-8","article-title":"In vitro effects of ketone bodies, glucocorticosteroids and bovine pregnancy-associated glycoprotein on cultures of bone marrow progenitor cells of cows and calves","volume":"68","author":"Hoeben","year":"1999","journal-title":"Veterinary Immunology and Immunopathology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0085","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/0093-691X(90)90025-O","article-title":"Blood constituents during the estrous cycle and early pregnancy in dairy cows","volume":"34","author":"Johnson","year":"1990","journal-title":"Theriogenology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0090","doi-asserted-by":"crossref","first-page":"207","DOI":"10.2460\/ajvr.1989.50.02.207","article-title":"Alterations in bovine neutrophil function during the periparturient period","volume":"50","author":"Kehrli","year":"1989","journal-title":"American Journal of Veterinary Research"},{"key":"10.1016\/j.rvsc.2010.07.019_b0095","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1051\/vetres:2003034","article-title":"The effect of milk production level on host resistance of dairy cows, as assessed by the severity of experimental Escherichia coli mastitis","volume":"34","author":"Kornalijnslijper","year":"2003","journal-title":"Veterinary Research"},{"key":"10.1016\/j.rvsc.2010.07.019_b0100","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1016\/0093-691X(96)00079-9","article-title":"Influence of management factors on pregnancy attrition in dairy cattle","volume":"45","author":"Labernia","year":"1996","journal-title":"Theriogenology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0105","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s00484-005-0273-3","article-title":"Lymphocyte functions in dairy cows in hot environment","volume":"50","author":"Lacetera","year":"2005","journal-title":"International Journal of Biometeorology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0110","doi-asserted-by":"crossref","first-page":"4606","DOI":"10.3168\/jds.S0022-0302(06)72510-3","article-title":"Heat stress elicits different responses in peripheral blood mononuclear cells from Brown Swiss and Holstein cows","volume":"89","author":"Lacetera","year":"2006","journal-title":"Journal of Dairy Science"},{"key":"10.1016\/j.rvsc.2010.07.019_b0115","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3168\/jds.S0022-0302(76)84163-X","article-title":"Effect of temperature-season on bovine adrenal cortical function, blood cell profile, and milk production","volume":"59","author":"Lee","year":"1976","journal-title":"Journal of Dairy Science"},{"key":"10.1016\/j.rvsc.2010.07.019_b0120","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0093-691X(02)01359-6","article-title":"Is fertility declining in dairy cattle? A retrospective study in northeastern Spain","volume":"60","author":"L\u00f3pez-Gatius","year":"2003","journal-title":"Theriogenology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0125","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.theriogenology.2003.11.002","article-title":"Neospora caninum infection does not affect early pregnancy in dairy cattle","volume":"62","author":"L\u00f3pez-Gatius","year":"2004","journal-title":"Theriogenology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0130","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1111\/j.1439-0450.2004.00779.x","article-title":"Neospora-associated abortion episode over a 1-year period in a dairy herd in north-east Spain","volume":"51","author":"L\u00f3pez-Gatius","year":"2004","journal-title":"Journal of Veterinary Medicine. B, Infectious diseases and Veterinary Public Health"},{"key":"10.1016\/j.rvsc.2010.07.019_b0135","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.theriogenology.2006.08.014","article-title":"Plasma pregnancy-associated glycoprotein-1 (PAG-1) concentrations during gestation in Neospora-infected dairy cows","volume":"67","author":"L\u00f3pez-Gatius","year":"2007","journal-title":"Theriogenology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0140","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.domaniend.2005.12.007","article-title":"Milk production correlates negatively with plasma levels of pregnancy-associated glycoprotein (PAG) during the early fetal period in high producing dairy cows with live fetuses","volume":"32","author":"L\u00f3pez-Gatius","year":"2007","journal-title":"Domestic Animal Endocrinology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0145","doi-asserted-by":"crossref","first-page":"3268","DOI":"10.3168\/jds.S0022-0302(02)74415-9","article-title":"Blood and milk neutrophil chemiluminescence and viability in primiparous and pluriparous dairy cows during late pregnancy, around parturition and early lactation","volume":"85","author":"Mehrzad","year":"2002","journal-title":"Journal of Dairy Science"},{"key":"10.1016\/j.rvsc.2010.07.019_b0150","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1017\/S0022029908003439","article-title":"T lymphocyte proliferative capacity and CD4+\/CD8+ ratio in primiparous and pluriparous lactating cows","volume":"75","author":"Mehrzad","year":"2008","journal-title":"Journal of Dairy Research"},{"key":"10.1016\/j.rvsc.2010.07.019_b0155","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.vetmic.2008.09.001","article-title":"Phagocytic and bactericidal activity of blood and milk-resident neutrophils against Staphylococcus aureus in primiparous and multiparous cows during early lactation","volume":"134","author":"Mehrzad","year":"2009","journal-title":"Veterinary Microbiology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0160","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0093-691X(98)00077-6","article-title":"Increased risk of abortion following Neospora caninum abortion outbreaks: a retrospective and prospective cohort study in four dairy herds","volume":"49","author":"Moen","year":"1998","journal-title":"Theriogenology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0165","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.rvsc.2006.10.017","article-title":"Hematology and serum biochemistry of Holstein dairy calves: age related changes and comparison with blood composition in adults","volume":"83","author":"Mohri","year":"2007","journal-title":"Research in Veterinary Science"},{"key":"10.1016\/j.rvsc.2010.07.019_b0170","unstructured":"National Research Council. Nutrient Requirements of dairy cattle, 2001 seventh rev. ed., Washington, DC: National Academic Science."},{"key":"10.1016\/j.rvsc.2010.07.019_b0175","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s00580-008-0730-6","article-title":"Hematological changes of dairy cows in postpartum period and early pregnancy","volume":"17","author":"Nazifi","year":"2008","journal-title":"Comparative Clinical Pathology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0180","first-page":"111","article-title":"Phagocytic activity of bovine leukocytes during pregnancy","volume":"40","author":"Newbould","year":"1976","journal-title":"Canadian Journal of Comparative Medicine"},{"key":"10.1016\/j.rvsc.2010.07.019_b0185","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.vetpar.2007.06.032","article-title":"Dynamics of anti-Neospora caninum antibodies during gestation in chronically infected dairy cows","volume":"148","author":"Nogareda","year":"2007","journal-title":"Veterinary Parasitology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0190","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1530\/REP-08-0218","article-title":"Deviations in populations of peripheral blood mononuclear cells and endometrial macrophages in the cow during pregnancy","volume":"136","author":"Oliveira","year":"2008","journal-title":"Reproduction"},{"key":"10.1016\/j.rvsc.2010.07.019_b0195","unstructured":"Schalm, O.W., Jain, N.C., Carrol, E.J., 1975. Veterinary hematology third ed. Philadelphia, Lee and Fibiger, 807 p."},{"key":"10.1016\/j.rvsc.2010.07.019_b0200","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0304-4017(98)00195-2","article-title":"The efficiency of vertical transmission of Neospora caninum in dairy cattle analysed by serological techniques","volume":"80","author":"Schares","year":"1998","journal-title":"Veterinary Parasitology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0205","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/j.1439-0531.2007.01025.x","article-title":"Factors affecting plasma pregnancy-associated glycoprotein-1 concentrations throughout gestation in high producing dairy cows","volume":"44","author":"Serrano","year":"2009","journal-title":"Reproduction in Domestic Animals"},{"key":"10.1016\/j.rvsc.2010.07.019_b0210","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1071\/RD9900129","article-title":"Production and regulation of progesterone in bovine corpus luteum and placenta in mid and late gestation: a personal review","volume":"2","author":"Shemesh","year":"1990","journal-title":"Reproduction, Fertility and Development"},{"year":"2001","series-title":"Large Animal Internal Medicine","author":"Smith","key":"10.1016\/j.rvsc.2010.07.019_b0215"},{"key":"10.1016\/j.rvsc.2010.07.019_b0220","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.vetimm.2006.03.017","article-title":"Toxoplasma gondii and Neospora caninum infections of bovine endothelial cells induce endothelial adhesion molecule gene transcription and subsequent PMN adhesion","volume":"112","author":"Taubert","year":"2006","journal-title":"Veterinary Immunology and Immunopathology"},{"key":"10.1016\/j.rvsc.2010.07.019_b0225","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.2460\/ajvr.1997.58.12.1381","article-title":"Effect of congenitally acquired Neospora caninum infection on risk of abortion and subsequent abortions in dairy cattle","volume":"58","author":"Thurmond","year":"1997","journal-title":"American Journal of Veterinary Research"},{"key":"10.1016\/j.rvsc.2010.07.019_b0230","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0031-6997(24)01456-X","article-title":"Neutrophil migration mechanisms, with an emphasis on the pulmonary vasculature","volume":"52","author":"Wagner","year":"2000","journal-title":"Pharmacological Reviews"},{"key":"10.1016\/j.rvsc.2010.07.019_b0235","doi-asserted-by":"crossref","first-page":"949","DOI":"10.3168\/jds.S0022-0302(76)84303-2","article-title":"Effect of stress on blood leucocyte and milk somatic cell counts in dairy cows","volume":"59","author":"Wegner","year":"1976","journal-title":"Journal of Dairy Science"},{"key":"10.1016\/j.rvsc.2010.07.019_b0240","first-page":"699","article-title":"Some factors affecting the abortion rate in dairy herds with high incidence of Neospora-associated abortions are different in cows and heifers","volume":"45","author":"Y\u00e1niz","year":"2010","journal-title":"Reproduction in Domestic Animals"}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528810002559?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528810002559?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T03:50:09Z","timestamp":1758513009000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034528810002559"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":48,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0034528810002559"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2010.07.019","relation":{},"ISSN":["0034-5288"],"issn-type":[{"type":"print","value":"0034-5288"}],"subject":[],"published":{"date-parts":[[2011,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Peripheral white blood cell counts throughout pregnancy in non-aborting Neospora caninum-seronegative and seropositive high-producing dairy cows in a Holstein Friesian herd","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2010.07.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}