{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T22:58:17Z","timestamp":1776466697565,"version":"3.51.2"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.rvsc.2015.05.013","type":"journal-article","created":{"date-parts":[[2015,5,27]],"date-time":"2015-05-27T04:12:30Z","timestamp":1432699950000},"page":"6-10","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Expression of inflammation-associated genes in circulating leukocytes and activity of indoleamine-2,3-dioxygenase in dairy cattle with acute puerperal metritis and bacteremia"],"prefix":"10.1016","volume":"101","author":[{"given":"Brent C.","family":"Credille","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amelia R.","family":"Woolums","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael W.","family":"Overton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Hurley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steeve","family":"Gigu\u00e8re","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"Suppl. 1","key":"10.1016\/j.rvsc.2015.05.013_bb0005","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/SHK.0b013e3181e7e61b","article-title":"Neutrophil paralysis in sepsis","volume":"34","author":"Alves-Filho","year":"2010","journal-title":"Shock"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0010","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/S0092-8674(04)00451-9","article-title":"Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells","volume":"117","author":"Amsen","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0015","doi-asserted-by":"crossref","DOI":"10.1111\/jvim.12418","article-title":"Prevalence of bacteremia in dairy cattle with acute puerperal metritis","author":"Credille","year":"2014","journal-title":"Journal of Veterinary Internal Medicine"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0020","first-page":"26","article-title":"The regulation of CD4 T cell differentiation","volume":"9","author":"Flavell","year":"1998","journal-title":"European Cytokine Network"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0025","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.theriogenology.2011.08.008","article-title":"Evaluation of cytokine expression by blood monocytes of lactating Holstein cows with or without postpartum uterine disease","volume":"77","author":"Galvao","year":"2012","journal-title":"Theriogenology"},{"issue":"4","key":"10.1016\/j.rvsc.2015.05.013_bb0030","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1097\/CCM.0000000000000100","article-title":"Immunological characterization of compensatory anti-inflammatory response syndrome in patients with severe sepsis: a longitudinal study","volume":"42","author":"Gomez","year":"2014","journal-title":"Critical Care Medicine"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0035","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1071\/RD10230","article-title":"Immunological mechanisms to establish embryo tolerance in early bovine pregnancy","volume":"23","author":"Groebner","year":"2011","journal-title":"Reproduction, Fertility and Development"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0040","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1097\/SHK.0b013e3181ad3195","article-title":"High activity of indoleamine 2,3 dioxygenase enzyme predicts disease severity and case fatality in bacteremic patients","volume":"33","author":"Huttunen","year":"2010","journal-title":"Shock"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0045","doi-asserted-by":"crossref","first-page":"3146","DOI":"10.4049\/jimmunol.0803104","article-title":"Blockade of indoleamine 2,3-dioxygenase protects mice against lipopolysaccharide-induced endotoxin shock","volume":"182","author":"Jung","year":"2009","journal-title":"Journal of Immunology"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0050","doi-asserted-by":"crossref","first-page":"215","DOI":"10.2460\/ajvr.1989.50.02.215","article-title":"Alterations in bovine lymphocyte function during the periparturient period","volume":"50","author":"Kehrli","year":"1989","journal-title":"American Journal of Veterinary Research"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0055","doi-asserted-by":"crossref","first-page":"207","DOI":"10.2460\/ajvr.1989.50.02.207","article-title":"Alterations in bovine neutrophil function during the periparturient period","volume":"50","author":"Kehrli","year":"1989","journal-title":"American Journal of Veterinary Research"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0060","doi-asserted-by":"crossref","first-page":"315","DOI":"10.3168\/jds.S0022-0302(99)75238-0","article-title":"Phenotype analysis of peripheral blood mononuclear cells in periparturient dairy cows","volume":"82","author":"Kimura","year":"1999","journal-title":"Journal of Dairy Science"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0065","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1093\/clinchem\/48.3.579","article-title":"More rapid method for simultaneous measurement of tryptophan and kynurenine by HPLC","volume":"48","author":"Laich","year":"2002","journal-title":"Clinical Chemistry"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0070","series-title":"Fundamental Immunology","article-title":"Type I cytokines and interferons, and their receptors","author":"Leonard","year":"2013"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0075","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.1939-1676.2012.00905.x","article-title":"The immunopathology of sepsis: pathogen recognition, systemic inflammation, the compensatory anti-inflammatory response, and regulatory T cells","volume":"26","author":"Lewis","year":"2012","journal-title":"Journal of Veterinary Internal Medicine"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0080","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.it.2012.10.001","article-title":"Indoleamine 2,3 dioxygenase and metabolic control of immune responses","volume":"34","author":"Munn","year":"2013","journal-title":"Trends in Immunology"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0085","series-title":"Janeway's Immunobiology","author":"Murphy","year":"2012"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0090","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/cc9371","article-title":"Platelets, endothelium and shear join forces to mislead neutrophils in sepsis","volume":"15","author":"Neto","year":"2011","journal-title":"Critical Care"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0095","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1530\/REP-08-0218","article-title":"Deviations in populations of peripheral blood mononuclear cells and endometrial macrophages in the cow during pregnancy","volume":"136","author":"Oliveira","year":"2008","journal-title":"Reproduction"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0100","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/29.9.e45","article-title":"A new mathematical model for relative quantification in real-time RT-PCR","volume":"29","author":"Pfaffl","year":"2001","journal-title":"Nucleic Acids Research"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0105","doi-asserted-by":"crossref","first-page":"3821","DOI":"10.1128\/IAI.05204-11","article-title":"Indoleamine 2,3-dioxygenase, tryptophan catabolism, and Mycobacterium avium subsp. paratuberculosis: a model for chronic mycobacterial infections","volume":"79","author":"Plain","year":"2011","journal-title":"Infection and Immunity"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0110","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1097\/00024382-200209000-00001","article-title":"Cellular apoptosis and organ injury in sepsis: a review","volume":"18","author":"Power","year":"2002","journal-title":"Shock"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0115","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1084\/jem.185.3.461","article-title":"Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells","volume":"185","author":"Rincon","year":"1997","journal-title":"Journal of Experimental Medicine"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0125","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1016\/j.theriogenology.2005.08.021","article-title":"Defining postpartum uterine disease in cattle","volume":"65","author":"Sheldon","year":"2006","journal-title":"Theriogenology"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0120","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1095\/biolreprod.109.077370","article-title":"Defining postpartum uterine disease and the mechanisms of infection and immunity in the female reproductive tract in cattle","volume":"81","author":"Sheldon","year":"2009","journal-title":"Biology of Reproduction"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0130","doi-asserted-by":"crossref","first-page":"4496","DOI":"10.1128\/IAI.00310-09","article-title":"Indoleamine 2,3-dioxygenase is involved in defense against Neospora caninum in human and bovine cells","volume":"77","author":"Spekker","year":"2009","journal-title":"Infection and Immunity"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0135","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.vetimm.2012.09.004","article-title":"Down-regulation of NOD1 in neutrophils of periparturient dairy cows","volume":"150","author":"Tan","year":"2012","journal-title":"Veterinary Immunology and Immunopathology"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0140","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1097\/00003246-200205000-00010","volume":"30","author":"Tschaikowsky","year":"2002","journal-title":"Critical Care Medicine"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0145","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.ccm.2008.06.010","article-title":"The compensatory anti-inflammatory response syndrome (CARS) in critically ill patients","volume":"29","author":"Ward","year":"2008","journal-title":"Clinics in Chest Medicine"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0150","doi-asserted-by":"crossref","first-page":"976","DOI":"10.2460\/javma.2001.219.976","article-title":"Bacteremia associated with naturally occurring acute coliform mastitis in dairy cows","volume":"219","author":"Wenz","year":"2001","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0155","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.theriogenology.2007.04.056","article-title":"The relationship between uterine pathogen growth density and ovarian function in the postpartum dairy cow","volume":"68","author":"Williams","year":"2007","journal-title":"Theriogenology"},{"key":"10.1016\/j.rvsc.2015.05.013_bb0160","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1182\/blood.V96.1.218","article-title":"Impaired antigen presentation by human monocytes during endotoxin tolerance","volume":"96","author":"Wolk","year":"2000","journal-title":"Blood"}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528815001587?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528815001587?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T04:00:46Z","timestamp":1758513646000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034528815001587"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":32,"alternative-id":["S0034528815001587"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2015.05.013","relation":{},"ISSN":["0034-5288"],"issn-type":[{"value":"0034-5288","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Expression of inflammation-associated genes in circulating leukocytes and activity of indoleamine-2,3-dioxygenase in dairy cattle with acute puerperal metritis and bacteremia","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2015.05.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}