{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:44:23Z","timestamp":1761489863517,"version":"3.44.0"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.1016\/j.rvsc.2016.01.007","type":"journal-article","created":{"date-parts":[[2016,1,14]],"date-time":"2016-01-14T10:05:55Z","timestamp":1452765955000},"page":"36-40","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Comparison of the isoflurane concentration of using dexketoprofen or methadone at premedication during orthopedic surgery in dogs"],"prefix":"10.1016","volume":"105","author":[{"given":"Roc\u00edo","family":"Navarrete-Calvo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1lvaro J.","family":"Guti\u00e9rrez-Bautista","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda M.","family":"Granados","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan M.","family":"Dom\u00ednguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Andr\u00e9s","family":"Fern\u00e1ndez-Sarmiento","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Setefilla","family":"Quir\u00f3s-Carmona","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Morgaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.rvsc.2016.01.007_bb0005","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1111\/j.1467-2995.2010.00563.x","article-title":"Comparison of analgesia provided by lidocaine, lidocaine-morphine or lidocaine-tramadol delivered epidurally in dogs following orchiectomy","volume":"37","author":"Almeida","year":"2010","journal-title":"Vet. Anaesth. Analg."},{"issue":"1","key":"10.1016\/j.rvsc.2016.01.007_bb0010","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1467-2995.2010.00576.x","article-title":"Two doses of dexmedetomidine in combination with buprenorphine for premedication in dogs; a comparison with acepromazine and buprenorphine","volume":"38","author":"Bell","year":"2011","journal-title":"Vet. Anaesth. Analg."},{"issue":"6","key":"10.1016\/j.rvsc.2016.01.007_bb0015","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1111\/j.1467-2995.2012.00744.x","article-title":"Comparison of analgesic efficacy of epidural methadone or ropivacaine\/methadone with or without pre-operative oral tepoxalin in dogs undergoing tuberositas tibiae advancement surgery","volume":"39","author":"Bosmans","year":"2012","journal-title":"Vet. Anaesth. Analg."},{"issue":"3","key":"10.1016\/j.rvsc.2016.01.007_bb0020","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1024\/0036-7281\/a000308","article-title":"Preemptive carprofen for peri-operative analgesia in dogs undergoing tibial plateau leveling osteotomy (TPLO): a prospective, randomized, blinded, placebo controlled clinical trial","volume":"154","author":"Bufalari","year":"2012","journal-title":"Schweiz. Arch. Tierheilkd."},{"key":"10.1016\/j.rvsc.2016.01.007_bb0025","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1111\/vaa.12172","article-title":"Cardiorespiratory, sedative and antinociceptive effects of dexmedetomidine alone or in combination with methadone, morphine or tramadol in dogs","volume":"41","author":"Cardoso","year":"2014","journal-title":"Vet. Anaesth. Analg."},{"issue":"11","key":"10.1016\/j.rvsc.2016.01.007_bb0030","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1111\/j.1751-0813.1999.tb12907.x","article-title":"Advantages and disadvantages or using alpha-2 agonists in veterinary practice","volume":"77","author":"Dart","year":"1999","journal-title":"Aust. Vet. J."},{"issue":"9","key":"10.1016\/j.rvsc.2016.01.007_bb0035","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1748-5827.1998.tb03748.x","article-title":"Endoscopy of the gastroduodenal mucosa after carprofen, meloxicam and ketoprofen administration in dogs","volume":"39","author":"Forsyth","year":"1998","journal-title":"J. Small Anim. Pract."},{"issue":"3","key":"10.1016\/j.rvsc.2016.01.007_bb0040","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1365-2885.2006.00732.x","article-title":"Dexmedetomidine or medetomidine premedication before propofol-desflurane anaesthesia in dogs","volume":"29","author":"G\u00f3mez-Villamandos","year":"2006","journal-title":"J. Vet. Pharmacol. Ther."},{"key":"10.1016\/j.rvsc.2016.01.007_bb0045","series-title":"Lumb & Jones'Veterinary Anesthesia and Analgesia","first-page":"31","article-title":"Pain and Its Management","author":"Hellyer","year":"2007"},{"issue":"1","key":"10.1016\/j.rvsc.2016.01.007_bb0050","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1467-2995.2009.00476.x","article-title":"Clinical pharmacology of methadone in dogs","volume":"37","author":"Ingvast-Larsson","year":"2010","journal-title":"Vet. Anaesth. Analg."},{"key":"10.1016\/j.rvsc.2016.01.007_bb0055","series-title":"BSAVA Manual of Canine and Feline Anaesthesia and Analgesia","first-page":"89","article-title":"Pain Management, Systemic Analgesics","author":"Kerr","year":"2007"},{"issue":"7","key":"10.1016\/j.rvsc.2016.01.007_bb0060","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.2460\/javma.2000.217.1025","article-title":"Effects of butorphanol and carprofen on the minimal alveolar concentration of isoflurane in dogs","volume":"217","author":"Ko","year":"2000","journal-title":"J. Am. Vet. Med. Assoc."},{"issue":"1","key":"10.1016\/j.rvsc.2016.01.007_bb0065","doi-asserted-by":"crossref","first-page":"19","DOI":"10.5326\/0450019","article-title":"Effects of carprofen and morphine on the minimum alveolar concentration of isoflurane in dogs","volume":"45","author":"Ko","year":"2009","journal-title":"J. Am. Anim. Hosp. Assoc."},{"key":"10.1016\/j.rvsc.2016.01.007_bb0070","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/j.1467-2995.2007.00369.x","article-title":"The disposition and behavioral effects of methadone in greyhounds","volume":"35","author":"Kukanich","year":"2008","journal-title":"Vet. Anaesth. Analg."},{"key":"10.1016\/j.rvsc.2016.01.007_bb0075","doi-asserted-by":"crossref","first-page":"664","DOI":"10.2460\/ajvr.69.5.664","article-title":"Effects of ketoconazole on the pharmacokinetics and pharmacodynamics of morphine in healthy greyhounds","volume":"69","author":"Kukanich","year":"2008","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.rvsc.2016.01.007_bb0080","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/j.1365-2885.2005.00681.x","article-title":"The effects of inhibiting cytochrome P450 3A, p-glycoprotein, and gastric acid secretion on the oral bioavailability of methadone in dogs","volume":"28","author":"Kukanich","year":"2005","journal-title":"J. Vet. Pharmacol. Ther."},{"key":"10.1016\/j.rvsc.2016.01.007_bb0085","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1111\/j.1365-2885.2005.00661.x","article-title":"Pharmacokinetics of morphine and plasma concentrations of morphine-6-glucuronide following morphine administration to dogs","volume":"28","author":"Kukanich","year":"2005","journal-title":"J. Vet. Pharmacol. Ther."},{"key":"10.1016\/j.rvsc.2016.01.007_bb0090","article-title":"Use of a von Frey device for evaluation of pharmacokinetics and pharmacodynamics of morphine after intravenous administration as an infusion or multiple doses in dogs","volume":"1968-1974","author":"Kukanich","year":"2005","journal-title":"Am. J. Vet. Res."},{"issue":"1","key":"10.1016\/j.rvsc.2016.01.007_bb0095","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1046\/j.1365-2885.2000.00245.x","article-title":"Clinical effects and pharmacokinetics of medetomidine and its enantiomers in dogs","volume":"23","author":"Kuusela","year":"2000","journal-title":"J. Vet. Pharmacol. Ther."},{"key":"10.1016\/j.rvsc.2016.01.007_bb0100","series-title":"Lumb & Jones'Veterinary Anesthesia and Analgesia","first-page":"241","article-title":"Opioids, Nonsteroidal Ani-inflammatories, and Analgesia Adjuvants","author":"Lamont","year":"2007"},{"issue":"2","key":"10.1016\/j.rvsc.2016.01.007_bb0105","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/j.1467-2995.2005.00239.x","article-title":"A comparison of extradural and intravenous methadone on intraoperative isoflurane and postoperative analgesia requirements in dogs","volume":"33","author":"Leibetseder","year":"2006","journal-title":"Vet. Anaesth. Analg."},{"key":"10.1016\/j.rvsc.2016.01.007_bb0110","series-title":"BSAVA Manual of Canine and Feline Anaesthesia and Analgesia","first-page":"150","article-title":"Inhalant Anaesthetics","author":"Matthews","year":"2007"},{"issue":"Suppl. 5","key":"10.1016\/j.rvsc.2016.01.007_bb0115","doi-asserted-by":"crossref","first-page":"24","DOI":"10.2165\/00003495-199600525-00005","article-title":"Preclinical and clinical development of dexketoprofen","volume":"52","author":"Maule\u00f3n","year":"1996","journal-title":"Drugs"},{"issue":"1","key":"10.1016\/j.rvsc.2016.01.007_bb0120","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/vaa.12086","article-title":"Electrocardiographic evaluation of the degree of sedation with three doses of methadone in healthy dogs","volume":"41","author":"Menegheti","year":"2014","journal-title":"Vet. Anaesth. Analg."},{"issue":"1","key":"10.1016\/j.rvsc.2016.01.007_bb0125","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.rvsc.2013.03.003","article-title":"Postoperative analgesic effects of dexketoprofen, buprenorphine and tramadol in dogs undergoing ovariohysterectomy","volume":"95","author":"Morgaz","year":"2013","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.rvsc.2016.01.007_bb0130","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.rvsc.2010.08.017","article-title":"Species comparison of enantioselective oral bioavailability and pharmacokinetics of ketoprofen","volume":"91","author":"Neirinckx","year":"2011","journal-title":"Res. Vet. Sci."},{"issue":"1","key":"10.1016\/j.rvsc.2016.01.007_bb0135","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/j.1467-2995.2010.00577.x","article-title":"Clinical efficacy and cardiorespiratory effects of alfaxalone, or diazepam\/fentanyl for induction of anaesthesia in dogs that are a poor anaesthetic risk","volume":"38","author":"Psatha","year":"2011","journal-title":"Vet. Anaesth. Analg."},{"issue":"6","key":"10.1016\/j.rvsc.2016.01.007_bb0140","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1111\/j.1532-950X.1998.tb00539.x","article-title":"Hemodynamic effects or medetomidina in the dog: a dose titration study","volume":"27","author":"Pypendop","year":"1998","journal-title":"Vet. Surg."},{"issue":"2","key":"10.1016\/j.rvsc.2016.01.007_bb0145","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1213\/01.ANE.0000097849.18820.C4","article-title":"Meloxicam, a specific COX-2 inhibitor, does not enhance the isoflurane minimum alveolar concentration reduction produced by morphine in the rat","volume":"98","author":"Santos","year":"2004","journal-title":"Anesth. Analg."},{"issue":"6","key":"10.1016\/j.rvsc.2016.01.007_bb0150","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1002\/chir.530060608","article-title":"Stereoselective pharmacokinetics of methadone in beagle dogs","volume":"6","author":"Schmidt","year":"1994","journal-title":"Chirality"},{"issue":"3","key":"10.1016\/j.rvsc.2016.01.007_bb0155","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.rvsc.2014.03.021","article-title":"Pharmacokinetics of the individual enantiomer S-(+)-ketoprofen after intravenous and oral administration in dogs at two dose levels","volume":"96","author":"Serrano-Rodr\u00edguez","year":"2014","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.rvsc.2016.01.007_bb0160","first-page":"21","article-title":"Physiological role of alpha 2-adrenoreceptors in the regulation of vigilance and pain: effect of medetomidine","volume":"85","author":"Stenberg","year":"1989","journal-title":"Acta Vet. Scand. Suppl."},{"key":"10.1016\/j.rvsc.2016.01.007_bb0165","doi-asserted-by":"crossref","first-page":"91","DOI":"10.2460\/AJVR.2002.63.91","article-title":"Cyclooxygenase selectivity of nonsteroidal anti-inflammatory drugs in canine blood","volume":"63","author":"Streppa","year":"2002","journal-title":"Am. J. Vet. Res."},{"issue":"1","key":"10.1016\/j.rvsc.2016.01.007_bb0170","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1292\/jvms.13-0042","article-title":"Sparing effect of robenacoxib on the minimum alveolar concentration for blunting adrenergic response (MAC\u2013BAR) of sevoflurane in dogs","volume":"76","author":"Tamura","year":"2014","journal-title":"J. Vet. Med. Sci."},{"issue":"5","key":"10.1016\/j.rvsc.2016.01.007_bb0175","doi-asserted-by":"crossref","first-page":"770","DOI":"10.2460\/ajvr.67.5.770","article-title":"Effect of meloxicam and butorphanol on minimum alveolar concentration if isoflurane in rabbits","volume":"67","author":"Turner","year":"2006","journal-title":"Am. J. Vet. Res."},{"issue":"1","key":"10.1016\/j.rvsc.2016.01.007_bb0180","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1292\/jvms.70.29","article-title":"Effects of carprofen and meloxicam with or without butorphanol on the minimum alveolar concentration of sevoflurane in dogs","volume":"70","author":"Yamashita","year":"2008","journal-title":"J. Vet. Med. Sci."}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528816300091?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528816300091?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T04:03:24Z","timestamp":1758513804000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034528816300091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":36,"alternative-id":["S0034528816300091"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2016.01.007","relation":{},"ISSN":["0034-5288"],"issn-type":[{"type":"print","value":"0034-5288"}],"subject":[],"published":{"date-parts":[[2016,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of the isoflurane concentration of using dexketoprofen or methadone at premedication during orthopedic surgery in dogs","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2016.01.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}