{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T23:32:47Z","timestamp":1781739167133,"version":"3.54.5"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100009352","name":"Grand Slam Club","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009352","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1016\/j.rvsc.2017.08.005","type":"journal-article","created":{"date-parts":[[2017,8,10]],"date-time":"2017-08-10T00:47:47Z","timestamp":1502326067000},"page":"1-4","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Short communication: Alteration in blood parameters by enrofloxacin in juvenile lesser spotted dogfish (Scyliorhinus canicula, Linnaeus, 1758) after intramuscular injection"],"prefix":"10.1016","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7985-2972","authenticated-orcid":false,"given":"Annalisa","family":"Zaccaroni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos","family":"Perez-Lopez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"de la Casa Resino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianfranco","family":"Medri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Ceneri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7048-4544","authenticated-orcid":false,"given":"Simone","family":"Bertini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliviero","family":"Mordenti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luana","family":"Cortinovis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8603-8418","authenticated-orcid":false,"given":"Rubina","family":"Sirri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana","family":"Mandrioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rvsc.2017.08.005_bb0005","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1080\/03601239809373177","article-title":"Liver glutathione content and glutathione-dependent enzymes of two species of freshwater fish as bioindicators of chemical pollution","volume":"33","author":"Almar","year":"1998","journal-title":"J. Environ. Sci. Health B"},{"key":"10.1016\/j.rvsc.2017.08.005_bb0010","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.5897\/AJPP11.644","article-title":"Toxicology of baytril (enrofloxacin)","volume":"5","author":"Babaahmady","year":"2011","journal-title":"Afr. J. Pharm. Pharmacol"},{"key":"10.1016\/j.rvsc.2017.08.005_bb0015","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/560235","article-title":"Norfloxacin\u2014toxicity for zebrafish (Danio rerio) focused on oxidative stress parameters","volume":"2014","author":"Bartoskova","year":"2014","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0020","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1093\/clinids\/18.6.946","article-title":"Temafloxacin syndrome: review of 95 cases","volume":"18","author":"Blum","year":"1994","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0025","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0166-445X(85)90038-4","article-title":"The toxicology and metabolism of chlorothalonil in fish. I. Lethal levels for Salmo gairdneri, Galaxias maculatus, G. truttaceus and G. auratus and the fate of 14 C-TCIN in S. gairdneri","volume":"7","author":"Davies","year":"1985","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0030","doi-asserted-by":"crossref","first-page":"188","DOI":"10.2460\/ajvr.1995.56.02.188","article-title":"Cortical bone concentrations of enrofloxacin in dogs","volume":"56","author":"Duval","year":"1995","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0035","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.2460\/ajvr.1996.57.07.1025","article-title":"Pharmacokinetics of enrofloxacin in adult horses and concentration of the drug in serum, body fluids, and endometrial tissues after repeated intragastrically administered doses","volume":"57","author":"Giguere","year":"1996","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0040","first-page":"157","article-title":"Ciprofloxacin inhibits human hematopoietic cell growth: synergism with tumor necrosis factor and interferon","volume":"19","author":"Hahn","year":"1991","journal-title":"Exp. Hematol."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0045","doi-asserted-by":"crossref","first-page":"4976","DOI":"10.1016\/j.scitotenv.2010.07.044","article-title":"Brain acetylcholinesterase, malondialdehyde and reduced glutathione as biomarkers of continuous exposure of tench, Tinca tinca, to carbofuran or deltamethrin","volume":"408","author":"Hern\u00e1ndez-Moreno","year":"2010","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0050","series-title":"Biological Indicators of Stress in Fish, American Fisheries Symposium","first-page":"67","article-title":"Detoxication enzymes as indicators of environmental stress on fish","author":"Jimenez","year":"1990"},{"key":"10.1016\/j.rvsc.2017.08.005_bb0055","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/j.2042-3306.1997.tb03143.x","article-title":"Pharmacokinetics of enrofloxacin in horses after single intravenous and intramuscular administration","volume":"29","author":"Kaartinen","year":"1997","journal-title":"Equine Vet. J."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0060","first-page":"20","article-title":"Effect of enrofloxacin administration on haematological profile in broiler chicken-a safety pharmacology study","volume":"8","author":"Kumar","year":"2012","journal-title":"Indian J. Field Vet."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0065","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1111\/j.1365-2885.1996.tb00057.x","article-title":"Disposition of single-dose oral enrofloxacin in the horse","volume":"19","author":"Langston","year":"1996","journal-title":"J. Vet. Pharmacol. Ther."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0070","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/ajh.2830460420","article-title":"Hemolytic anemia and acute renal failure associated with temafloxacin-dependent antibodies","volume":"46","author":"Maguire","year":"1994","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0075","first-page":"577","article-title":"Clinical pharmacologic features of fluoroquinolone antimicrobial drugs","volume":"193","author":"Neer","year":"1988","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0080","doi-asserted-by":"crossref","first-page":"3298","DOI":"10.3390\/ijerph7083298","article-title":"Toxicity of the herbicide atrazine: effects on lipid peroxidation and activities of antioxidant enzymes in the freshwater fish Channa punctatus (Bloch)","volume":"7","author":"Nwani","year":"2010","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.rvsc.2017.08.005_bb0085","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/S0045-6535(00)00500-2","article-title":"Glutathione-dependent resistance of the European eel Anguilla anguilla to the herbicide molinate","volume":"45","author":"Pena-Llopis","year":"2001","journal-title":"Chemosphere"},{"key":"10.1016\/j.rvsc.2017.08.005_bb0090","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1637\/0005-2086(2002)046[0075:EOAOIV]2.0.CO;2","article-title":"Effect of antibiotics on in vitro and in vivo avian cartilage degradation","volume":"46","author":"Peters","year":"2002","journal-title":"Avian Dis."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0095","first-page":"52","article-title":"Haematobiochemical studies on induced ciprofloxacin toxicity in broilers (Gallus gallus domesticus)","volume":"7","author":"Sonkusale","year":"2011","journal-title":"Indian J. Field Vet."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0100","series-title":"Elasmobranch Husbandry Manual: Captive Care of Sharks, Rays, and Their Relatives","first-page":"447","article-title":"Pharmacology in elasmobranchs","author":"Stamper","year":"2004"},{"key":"10.1016\/j.rvsc.2017.08.005_bb0105","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.etap.2011.12.019","article-title":"Effect of chronic exposure to simazine on oxidative stress and antioxidant response in common carp (Cyprinus carpio L.)","volume":"33","author":"Stara","year":"2012","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0110","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1046\/j.1439-0442.2001.00332.x","article-title":"Investigation of biochemical and haematological side-effects of enrofloxacin in dogs","volume":"48","author":"Tra\u015f","year":"2001","journal-title":"J. Veterinary Med. Ser. A"},{"key":"10.1016\/j.rvsc.2017.08.005_bb0115","doi-asserted-by":"crossref","first-page":"40","DOI":"10.4236\/ojvm.2016.62006","article-title":"A review of enrofloxacin for veterinary use","volume":"6","author":"Trouchon","year":"2016","journal-title":"Open J. Vet. Med."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0120","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.aquaculture.2008.08.032","article-title":"Oxidative stress response of black tiger shrimp (Penaeus monodon) to enrofloxacin and to culture system","volume":"285","author":"Tu","year":"2008","journal-title":"Aquaculture"},{"key":"10.1016\/j.rvsc.2017.08.005_bb0125","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1016\/j.chemosphere.2012.12.006","article-title":"Chlorpyrifos-induced changes in oxidant\/antioxidant status and haematological parameters of Cyprinus carpio carpio: ameliorative effect of lycopene","volume":"90","author":"Ural","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.rvsc.2017.08.005_bb0130","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0166-445X(02)00064-4","article-title":"Inhibition of cytochrome P450 enzymes by enrofloxacin in the sea bass (Dicentrarchus labrax)","volume":"62","author":"Vaccaro","year":"2003","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0135","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1006\/eesa.1999.1778","article-title":"Changes in liver enzyme activity in the teleost Sparus aurata in response to cadmium intoxication","volume":"43","author":"Vaglio","year":"1999","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.rvsc.2017.08.005_bb0140","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1016\/j.chemosphere.2009.09.038","article-title":"Adverse effects of enrofloxacin when associated with environmental stress in Tra catfish (Pangasianodon hypophthalmus)","volume":"77","author":"Wang","year":"2009","journal-title":"Chemosphere"},{"key":"10.1016\/j.rvsc.2017.08.005_bb0145","series-title":"30th Annual International Association for Aquatic Animal Medicine","first-page":"87","article-title":"Pharmacokinetics of oral trovafloxacin administration in the little skate (Raja erinacea)","author":"Willens","year":"1999"}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528817304502?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528817304502?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T04:05:44Z","timestamp":1758513944000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034528817304502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":29,"alternative-id":["S0034528817304502"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2017.08.005","relation":{},"ISSN":["0034-5288"],"issn-type":[{"value":"0034-5288","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Short communication: Alteration in blood parameters by enrofloxacin in juvenile lesser spotted dogfish (Scyliorhinus canicula, Linnaeus, 1758) after intramuscular injection","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2017.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}