{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T02:36:51Z","timestamp":1785811011802,"version":"3.56.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.rvsc.2018.01.001","type":"journal-article","created":{"date-parts":[[2018,1,9]],"date-time":"2018-01-09T21:49:03Z","timestamp":1515534543000},"page":"19-26","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Pituitary size alteration and adverse effects of radiation therapy performed in 9 dogs with pituitary-dependent hypercortisolism"],"prefix":"10.1016","volume":"118","author":[{"given":"Harumi","family":"Sawada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiho","family":"Sugihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitomi","family":"Oda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshinori","family":"Sako","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rvsc.2018.01.001_bb0005","first-page":"1251","article-title":"Pituitary apoplexy-like disease in 4 dogs","volume":"21","author":"Bertolini","year":"2007","journal-title":"J. Vet. Intern. Med."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0010","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1136\/jnnp.71.4.542","article-title":"Precipitating factors in pituitary apoplexy","volume":"71","author":"Biousse","year":"2001","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.rvsc.2018.01.001_bb0015","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1111\/j.1939-1676.1999.tb01454.x","article-title":"Hypofractionated radiation therapy of brain masses in dogs: a retrospective analysis of survival of 83 cases (1991-1996)","volume":"13","author":"Brearley","year":"1999","journal-title":"J. Vet. Intern. Med."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0020","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1227\/00006123-198403000-00021","article-title":"Pituitary apoplexy: a review","volume":"14","author":"Cardoso","year":"1984","journal-title":"Neurosurgery"},{"key":"10.1016\/j.rvsc.2018.01.001_bb0025","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/j.1740-8261.2000.tb00426.x","article-title":"Magnetic resonance imaging of otitis media in a dog","volume":"41","author":"Dvir","year":"2000","journal-title":"Vet. Radiol. Ultrasound"},{"key":"10.1016\/j.rvsc.2018.01.001_bb0030","series-title":"Canine and Feline Endocrinology and Reproduction","first-page":"252","article-title":"Canine hyperadrenocorticism","author":"Feldman","year":"2004"},{"key":"10.1016\/j.rvsc.2018.01.001_bb0035","first-page":"481","article-title":"Effects of radiotherapy on pituitary corticotroph macrotumors in dogs: a retrospective study of 12 cases","volume":"48","author":"de Fornel","year":"2007","journal-title":"Can. Vet. J."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0040","doi-asserted-by":"crossref","first-page":"374","DOI":"10.2460\/javma.1998.212.03.374","article-title":"Efficacy of cobalt 60 radiotherapy in dogs with pituitary-dependent hyperadrenocorticism","volume":"212","author":"Goossens","year":"1998","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0045","doi-asserted-by":"crossref","first-page":"830","DOI":"10.3171\/JNS-07\/10\/0830","article-title":"Prognostic factors for outcome after transsphenoidal hypophysectomy in dogs with pituitary-dependent hyperadrenocorticism","volume":"107","author":"Hanson","year":"2007","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0050","first-page":"1619","article-title":"Biochemical assessment of Cushing's disease in patients with corticotroph macroadenomas","volume":"83","author":"Katznelson","year":"1998","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0055","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1111\/j.1939-1676.2007.tb03060.x","article-title":"Survival, neurologic response, and prognostic factors in dogs with pituitary masses treated with radiation therapy and untreated dogs","volume":"21","author":"Kent","year":"2007","journal-title":"J. Vet. Intern. Med."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0060","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1677\/joe.0.1520387","article-title":"Correlation between impairment of glucocorticoid feedback and the size of the pituitary gland in dogs with pituitary-dependent hyperadrenocorticism","volume":"152","author":"Kooistra","year":"1997","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0065","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1002\/hed.24267","article-title":"Effects of radiation on the temporal bone in patients with head and neck cancer","volume":"38","author":"Lambert","year":"2016","journal-title":"Head Neck"},{"key":"10.1016\/j.rvsc.2018.01.001_bb0070","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1111\/j.1468-1331.2011.03619.x","article-title":"Predisposing factors of pituitary hemorrhage","volume":"19","author":"Liu","year":"2012","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0075","doi-asserted-by":"crossref","first-page":"179","DOI":"10.3171\/2014.8.GKS141439","article-title":"Clinical and pathological analysis of benign brain tumors resected after gamma knife surgery","volume":"121","author":"Liu","year":"2014","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0080","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1111\/j.1748-5827.2003.tb00110.x","article-title":"Suspected pituitary apoplexy in a German shorthaired pointer","volume":"44","author":"Long","year":"2003","journal-title":"J. Small Anim. Pract."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0085","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1111\/vru.12270","article-title":"Comparison of two coarse fractionated radiation protocols for the Management of Canine Pituitary Macrotumor: an observational study of 24 dogs","volume":"56","author":"Marcinowska","year":"2015","journal-title":"Vet. Radiol. Ultrasound"},{"key":"10.1016\/j.rvsc.2018.01.001_bb0090","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0303-7207(02)00283-6","article-title":"Progress in transsphenoidal hypophysectomy for treatment of pituitary-dependent hyperadrenocorticism in dogs and cats","volume":"197","author":"Meij","year":"2002","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0095","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.2460\/javma.1989.194.11.1612","article-title":"Pituitary macroadenomas and macroadenocarcinomas in dogs treated with mitotane for pituitary-dependent hyperadrenocorticism: 13 cases (1981-1986)","volume":"194","author":"Nelson","year":"1989","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0100","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1556\/004.2016.040","article-title":"Evaluation of the occurrence of canine congenital sensorineural deafness in puppies of predisposed dog breeds using the brainstem auditory evoked response","volume":"64","author":"P\u0142onek","year":"2016","journal-title":"Acta Vet. Hung."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0105","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s11259-016-9668-3","article-title":"A comparison of the brainstem auditory evoked response in healthy ears of unilaterally deaf dogs and bilaterally hearing dogs","volume":"41","author":"P\u0142onek","year":"2017","journal-title":"Vet. Res. Commun."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0110","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1111\/jvim.14367","article-title":"The influence of pituitary size on outcome after transsphenoidal hypophysectomy in a large cohort of dogs with pituitary-dependent hypercortisolism","volume":"30","author":"van Rijn","year":"2016","journal-title":"J. Vet. Intern. Med."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0115","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.1016\/j.jstrokecerebrovasdis.2014.03.005","article-title":"Magnetic resonance imaging versus computed tomography for identification and quantification of intraventricular hemorrhage","volume":"23","author":"Romanova","year":"2014","journal-title":"J. Stroke Cerebrovasc. Dis."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0120","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1136\/vr.162.21.673","article-title":"Evaluation of cortisol precursors for the diagnosis of pituitary-dependent hyperadrenocorticism in dogs","volume":"162","author":"Ruckstuhl","year":"2008","journal-title":"Vet. Rec."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0125","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.domaniend.2005.09.004","article-title":"Cortisol, aldosterone, cortisol precursor, androgen and endogenous ACTH concentrations in dogs with pituitary-dependant hyperadrenocorticism treated with trilostane","volume":"31","author":"Sieber-Ruckstuhl","year":"2006","journal-title":"Domest. Anim. Endocrinol."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0130","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.domaniend.2008.10.002","article-title":"Trilostane-induced inhibition of cortisol secretion results in reduced negative feedback at the hypothalamic-pituitary axis","volume":"36","author":"Teshima","year":"2009","journal-title":"Domest. Anim. Endocrinol."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0135","doi-asserted-by":"crossref","first-page":"225","DOI":"10.2460\/javma.1998.213.02.225","article-title":"Megavoltage irradiation of pituitary macrotumors in dogs with neurologic signs","volume":"213","author":"Th\u00e9on","year":"1998","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.1016\/j.rvsc.2018.01.001_bb0140","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1002\/hed.23551","article-title":"Sensorineural hearing loss in patients with head and neck cancer after chemoradiotherapy and radiotherapy: a systematic review of the literature","volume":"37","author":"Theunissen","year":"2015","journal-title":"Head Neck"},{"key":"10.1016\/j.rvsc.2018.01.001_bb0145","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.2460\/javma.231.7.1081","article-title":"Diagnostic imaging findings and endocrine test results in dogs with pituitary-dependent hyperadrenocorticism that did or did not have neurologic abnormalities: 157 cases (1989-2005)","volume":"231","author":"Wood","year":"2007","journal-title":"J. Am. Vet. Med. Assoc."}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528816306944?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528816306944?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T04:07:21Z","timestamp":1758514041000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034528816306944"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":29,"alternative-id":["S0034528816306944"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2018.01.001","relation":{},"ISSN":["0034-5288"],"issn-type":[{"value":"0034-5288","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pituitary size alteration and adverse effects of radiation therapy performed in 9 dogs with pituitary-dependent hypercortisolism","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2018.01.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}