{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T03:10:06Z","timestamp":1773889806524,"version":"3.50.1"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002301","name":"Estonian Research Council","doi-asserted-by":"publisher","award":["IUT8-1"],"award-info":[{"award-number":["IUT8-1"]}],"id":[{"id":"10.13039\/501100002301","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.rvsc.2018.10.013","type":"journal-article","created":{"date-parts":[[2018,10,29]],"date-time":"2018-10-29T12:56:01Z","timestamp":1540817761000},"page":"117-123","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Acute phase response in organic lambs associated with colostrum serum amyloid A, weight gain, and Cryptosporidium and Giardia infections"],"prefix":"10.1016","volume":"121","author":[{"given":"Tarmo","family":"Niine","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristel","family":"Peetsalu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6478-7047","authenticated-orcid":false,"given":"Lea","family":"Tummeleht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ants","family":"Kuks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toomas","family":"Orro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rvsc.2018.10.013_bb0005","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/01652176.1994.9694410","article-title":"Concentrations of serum amyloid-A (SAA) and haptoglobin (HP) as parameters of inflammatory diseases in cattle","volume":"16","author":"Alsemgeest","year":"1994","journal-title":"Vet. Q."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0010","first-page":"3706","article-title":"Colostrum composition of Santa In\u00eas sheep and passive transfer of immunity to lambs","volume":"98","author":"Alves","year":"2015","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0015","doi-asserted-by":"crossref","first-page":"951","DOI":"10.2460\/javma.2005.226.951","article-title":"Evaluation of serum enzyme activities as predictors of passive transfer status in lambs","volume":"226","author":"Britti","year":"2005","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0020","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1017\/S0950268897007590","article-title":"Cryptosporidium parvum: oocyst excretion and viability patterns in experimentally infected lambs","volume":"119","author":"Bukhari","year":"1997","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0025","doi-asserted-by":"crossref","first-page":"4207","DOI":"10.1016\/j.jprot.2012.04.004","article-title":"Acute phase proteins in ruminants","volume":"75","author":"Ceciliani","year":"2012","journal-title":"J. Proteome"},{"key":"10.1016\/j.rvsc.2018.10.013_bb0030","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.prevetmed.2010.06.017","article-title":"Control of cryptosporidiosis in neonatal calves: use of halofuginone lactate in two different calf rearing systems","volume":"96","author":"De Waele","year":"2010","journal-title":"Prev. Vet. Med."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0035","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.vetpar.2017.09.023","article-title":"Haptoglobin and serum amyloid-a concentrations and their relationship with oocyst count in neonatal lambs experimentally infected with Cryptosporidium parvum","volume":"247","author":"Dinler","year":"2017","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0040","doi-asserted-by":"crossref","DOI":"10.1186\/1746-6148-4-1","article-title":"Maternal undernutrition and the ovine acute phase response to vaccination","volume":"4","author":"Eckersall","year":"2008","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0045","doi-asserted-by":"crossref","DOI":"10.1186\/1746-6148-10-85","article-title":"The effect of colostrum intake on blood plasma proteome profile in newborn lambs: low abundance proteins","volume":"10","author":"Hern\u00e1ndez-Castellano","year":"2014","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0050","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3168\/jds.2014-8143","article-title":"Colostrum protein uptake in neonatal lambs examined by descriptive and quantitative liquid chromatography-tandem mass spectrometry","volume":"98","author":"Hern\u00e1ndez-Castellano","year":"2015","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0055","doi-asserted-by":"crossref","first-page":"107","DOI":"10.5194\/aab-59-107-2016","article-title":"The effect of ewe body condition at lambing on growth of lambs and colostral specific gravity","volume":"59","author":"Karaku\u015f","year":"2016","journal-title":"Arch. Anim. Breed."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0060","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1017\/S0021859609990062","article-title":"The effect of offering concentrate supplement to twin- and triplet-bearing ewes grazing a 60 mm herbage sward height on lamb birth weight, heat production and post-natal growth","volume":"147","author":"Kerslake","year":"2009","journal-title":"J. Agric. Sci."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0065","first-page":"77","article-title":"Isolation of Eimeria oocysts from soil samples: a simple method described in detail","author":"Lassen","year":"2014","journal-title":"Agraart. J. Agric. Sci. XXV"},{"key":"10.1016\/j.rvsc.2018.10.013_bb0070","first-page":"7","article-title":"Gastrointestinal parasites of sheep on Estonian islands","author":"Lassen","year":"2013","journal-title":"Agraarteadus XXIV"},{"key":"10.1016\/j.rvsc.2018.10.013_bb0075","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1046\/j.1439-0450.2003.00629.x","article-title":"Blood and colostrum\/milk serum gamma-glutamyltransferase activity as a predictor of passive transfer status in lambs","volume":"50","author":"Maden","year":"2003","journal-title":"J. Vet. Med. B Infect. Dis Vet. Public Health"},{"key":"10.1016\/j.rvsc.2018.10.013_bb0080","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1292\/jvms1939.44.15","article-title":"Quantitative determination of bovine serum haptoglobin and its elevation in some inflammatory diseases","volume":"44","author":"Makimura","year":"1982","journal-title":"Nihon Juigaku Zasshi."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0085","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.vetpar.2004.11.033","article-title":"Immunization protocols against Cryptosporidium parvum in ovines: protection in suckling lambs","volume":"129","author":"Mart\u00edn-G\u00f3mez","year":"2005","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0090","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s00436-005-0031-9","article-title":"Obtaining hyperimmune anti-Cryptosporidium parvum ovine colostrum. A study of the humoral immune response in immunized sheep","volume":"98","author":"Mart\u00edn-G\u00f3mez","year":"2006","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0095","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0165-2427(01)00380-4","article-title":"Elevated extrahepatic expression and secretion of mammary-associated serum amyloid a 3 (M-SAA3) into colostrum","volume":"83","author":"McDonald","year":"2001","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0100","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1017\/S0022029913000484","article-title":"Use of milk amyloid a in the diagnosis of subclinical mastitis in dairy ewes","volume":"80","author":"Miglio","year":"2013","journal-title":"J. Dairy Res."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0105","doi-asserted-by":"crossref","first-page":"937","DOI":"10.3168\/jds.S0022-0302(01)74551-1","article-title":"Factors associated with colostral specific gravity in dairy cows","volume":"84","author":"Morin","year":"2001","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0110","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1017\/S0950268800001321","article-title":"Role of enteric pathogens in the aetiology of neonatal diarrhoea in lambs and goat kids in Spain","volume":"117","author":"Mu\u00f1oz","year":"1996","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0115","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.cvfa.2006.07.002","article-title":"Giardiasis and cryptosporidiosis in ruminants","volume":"22","author":"O'Handley","year":"2006","journal-title":"Vet. Clin. North Am. Food Anim. Pract."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0120","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.2460\/ajvr.1995.56.11.1470","article-title":"Effects of giardiasis on production in a domestic ruminant (lamb) model","volume":"56","author":"Olson","year":"1995","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0125","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.tvjl.2007.02.010","article-title":"Temporal changes in serum concentrations of acute phase proteins in newborn dairy calves","volume":"176","author":"Orro","year":"2008","journal-title":"Vet. J."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0130","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0304-4017(93)90006-9","article-title":"Serum antibody response in lambs naturally and experimentally infected with Cryptosporidium parvum","volume":"50","author":"Ortega-Mora","year":"1993","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0135","series-title":"10th International Veterinary Immunology Symposium. Milan, Italy","first-page":"36","article-title":"Temporal changes of serum amyloid A (SAA) concentrations in newborn lambs: effect of colostrum SAA concentrations and associations to the weight gain","author":"Peetsalu","year":"2013"},{"key":"10.1016\/j.rvsc.2018.10.013_bb0140","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0304-4017(01)00608-2","article-title":"Serum antibody response and Cryptosporidium parvum oocyst antigens recognized by sera from naturally infected sheep","volume":"104","author":"Qu\u00edlez","year":"2002","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0145","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s00248-003-0003-5","article-title":"Effects of the Norwegian winter environment on Giardia cysts and Cryptosporidium oocysts","volume":"47","author":"Robertson","year":"2004","journal-title":"Microb. Ecol."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0150","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0117433","article-title":"Proteomics-driven analysis of ovine whey colostrum","volume":"10","author":"Scumaci","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.rvsc.2018.10.013_bb0155","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1939-165X.2001.tb00248.x","article-title":"International standardization of acute phase proteins","volume":"30","author":"Skinner","year":"2001","journal-title":"Vet. Clin. Pathol."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0160","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.vetpar.2011.05.050","article-title":"Cryptosporidium and Giardia associated with reduced lamb carcase productivity","volume":"182","author":"Sweeny","year":"2011","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0165","first-page":"551","article-title":"Experimental infection of calves and sheep with bovine Giardia isolates","volume":"131","author":"Taminelli","year":"1989","journal-title":"Schweizer Arch. f\u00fcr Tierheilkd."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0170","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1136\/vr.133.6.131","article-title":"Giardiasis in lambs at pasture","volume":"133","author":"Taylor","year":"1993","journal-title":"Vet. Rec."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0175","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0304-4017(93)90172-J","article-title":"Diagnosis of Cryptosporidium on a sheep farm with neonatal diarrhea by immunofluorescence assays","volume":"47","author":"Xiao","year":"1993","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0180","doi-asserted-by":"crossref","first-page":"55","DOI":"10.2307\/3283345","article-title":"Periparturient rise in the excretion of Giardia sp. cysts and Cryptosporidium parvum oocysts as a source of infection for lambs","volume":"80","author":"Xiao","year":"1994","journal-title":"J. Parasitol."},{"key":"10.1016\/j.rvsc.2018.10.013_bb0185","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0304-4017(97)00187-8","article-title":"Serum immune response to Giardia duodenalis in experimentally infected lambs","volume":"75","author":"Yanke","year":"1998","journal-title":"Vet. Parasitol."}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528818304703?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528818304703?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T04:09:10Z","timestamp":1758514150000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034528818304703"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":37,"alternative-id":["S0034528818304703"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2018.10.013","relation":{},"ISSN":["0034-5288"],"issn-type":[{"value":"0034-5288","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acute phase response in organic lambs associated with colostrum serum amyloid A, weight gain, and Cryptosporidium and Giardia infections","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2018.10.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}