{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T21:53:44Z","timestamp":1788386024952,"version":"build-2803163510"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003627","name":"Rural Development Administration","doi-asserted-by":"publisher","award":["PJ01094401"],"award-info":[{"award-number":["PJ01094401"]}],"id":[{"id":"10.13039\/501100003627","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014579","name":"National Institute of Animal Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014579","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.rvsc.2019.01.025","type":"journal-article","created":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T05:28:30Z","timestamp":1548307710000},"page":"293-297","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["The 3D8 single chain variable fragment protein suppress infectious bronchitis virus transmission in the transgenic chickens"],"prefix":"10.1016","volume":"123","author":[{"given":"Gunsup","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoonsung","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanmugam","family":"Sureshkumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun Keun","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeom Sun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keon Bong","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung-Woon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeon","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Hoon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung June","family":"Byun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rvsc.2019.01.025_bb0005","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1017\/S0043933914000385","article-title":"An overview of infectious bronchitis virus in chickens","volume":"70","author":"Awad","year":"2014","journal-title":"Worlds. Poult. Sci. J."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0010","doi-asserted-by":"crossref","first-page":"5938","DOI":"10.1038\/s41598-017-05270-8","article-title":"Transgenic chickens expressing the 3D8 single chain variable fragment protein suppress avian influenza transmission","volume":"7","author":"Byun","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0015","series-title":"Diseases of Poultry","first-page":"511","article-title":"Infectious bursal disease","author":"Cavanagh","year":"1997"},{"key":"10.1016\/j.rvsc.2019.01.025_bb0020","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1746-6148-10-24","article-title":"Sambucus nigra extracts inhibit infectious bronchitis virus at an early point during replication","volume":"10","author":"Chen","year":"2014","journal-title":"BMC. Vet. Rec."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0025","doi-asserted-by":"crossref","first-page":"6838","DOI":"10.1128\/JVI.72.8.6838-6850.1998","article-title":"Coronavirus particle assembly: primary structure requirements of the membrane protein","volume":"72","author":"De Haan","year":"1998","journal-title":"J. Virol."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0030","doi-asserted-by":"crossref","first-page":"2272","DOI":"10.1016\/j.neurobiolaging.2014.04.031","article-title":"PERK mediates eIF2\u03b1 phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease","volume":"35","author":"Devi","year":"2014","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.rvsc.2019.01.025_bb0035","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1080\/03079450601156083","article-title":"Lithium chloride inhibits the coronavirus infectious bronchitis virus in cell culture","volume":"36","author":"Harrison","year":"2007","journal-title":"Avian Pathol."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0040","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0378-1119(91)90434-D","article-title":"Efficient selection for high-expression transfectants with a novel eukaryotic vector","volume":"108","author":"Hitoshi","year":"1991","journal-title":"Gene"},{"key":"10.1016\/j.rvsc.2019.01.025_bb0045","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1637\/7389-052905R.1","article-title":"Data from 11 years of molecular typing infectious bronchitis virus field isolates","volume":"49","author":"Jackwood","year":"2005","journal-title":"Avian Dis."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0050","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.virusres.2010.01.006","article-title":"Avian coronavirus infectious bronchitis virus susceptibility to botanical oleoresins and essential oils in vitro and in vivo","volume":"149","author":"Jackwood","year":"2010","journal-title":"Virus Res."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0055","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1007\/s00018-009-9179-2","article-title":"A nucleic acid-hydrolyzing antibody penetrates into cells via caveolae-mediated endocytosis, localizes in the cytosol and exhibits cytotoxicity","volume":"66","author":"Jang","year":"2009","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0060","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.bbrc.2010.04.032","article-title":"An RNA-hydrolyzing recombinant antibody exhibits an antiviral activity against classical swine fever virus","volume":"395","author":"Jun","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0065","doi-asserted-by":"crossref","first-page":"15287","DOI":"10.1074\/jbc.M600937200","article-title":"Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double-and single-stranded DNAs without sequence specificity","volume":"281","author":"Kim","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0070","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1081\/IMM-120016241","article-title":"Production and characterization of an anti-idiotypic single chain Fv that recognizes an anti-DNA antibody","volume":"3","author":"Kwon","year":"2002","journal-title":"Immunol. Investig."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-3527(08)60286-9","article-title":"The molecular biology of coronaviruses","volume":"48","author":"Lai","year":"1997","journal-title":"Adv. Virus Res."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0080","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004208","article-title":"A nucleic-acid hydrolyzing single chain antibody confers resistance to DNA virus infection in hela cells and C57BL\/6 mice","volume":"10","author":"Lee","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0085","doi-asserted-by":"crossref","first-page":"773","DOI":"10.14348\/molcells.2015.0073","article-title":"Therapeutic strategy for the prevention of pseudorabies virus infection in C57BL\/6 mice by 3D8 scFv with intrinsic nuclease activity","volume":"38","author":"Lee","year":"2015","journal-title":"Mol. Cell"},{"key":"10.1016\/j.rvsc.2019.01.025_bb0090","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1002\/ptr.3260","article-title":"Forsythoside a inhibits the avian infectious bronchitis virus in cell culture","volume":"25","author":"Li","year":"2011","journal-title":"Phytother. Res."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0095","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.meegid.2011.01.007","article-title":"An emerging recombinant cluster of nephropathogenic strains of avian infectious bronchitis virus in Korea","volume":"11","author":"Lim","year":"2011","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0100","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1080\/03079450600920984","article-title":"Infectious bronchitis virus: S1 gene characteristics of vaccines used in China and efficacy of vaccination against heterologous strains from China","volume":"35","author":"Liu","year":"2006","journal-title":"Avian Pathol."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0105","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1637\/8204-010708-Reg.1","article-title":"Transmissibility of infectious bronchitis virus H120 vaccine strain among broilers under experimental conditions","volume":"52","author":"Matthijs","year":"2008","journal-title":"Avian Dis."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0110","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1080\/03079459708419246","article-title":"Infectious bronchitis virus: immunopathogenesis of infection in the chicken","volume":"26","author":"Raj","year":"1997","journal-title":"Avian Pathol."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0115","first-page":"458","article-title":"The effect of Allium sativum (Garlic) extract on infectious bronchitis virus in specific pathogen free embryonic egg","volume":"6","author":"Shojai","year":"2016","journal-title":"Avicenna J. Phytomed."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0120","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1637\/0005-2086-47.s3.1079","article-title":"Development of real-time RT-PCR for the detection of avian influenza virus","volume":"47","author":"Spackman","year":"2003","journal-title":"Avian Dis."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0125","doi-asserted-by":"crossref","first-page":"5993","DOI":"10.1016\/j.febslet.2006.09.052","article-title":"Characterisation of the RNA binding properties of the coronavirus infectious bronchitis virus nucleocapsid protein amino-terminal region","volume":"580","author":"Spencer","year":"2006","journal-title":"FEBS Lett."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0130","doi-asserted-by":"crossref","first-page":"464","DOI":"10.3382\/ps.2009-00461","article-title":"Swine intestine antimicrobial peptides inhibit infectious bronchitis virus infectivity in chick embryos","volume":"89","author":"Sun","year":"2010","journal-title":"Poult. Sci."},{"key":"10.1016\/j.rvsc.2019.01.025_bb0135","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jviromet.2016.01.008","article-title":"Comparison between dot-immunoblotting assay and clinical sign determination method for quantifying avian infectious bronchitis virus vaccine by titration in embryonated eggs","volume":"230","author":"Yuk","year":"2016","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.rvsc.2019.01.025_bb0140","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.virol.2017.06.028","article-title":"Chicken mannose binding lectin has antiviral activity towards infectious bronchitis virus","volume":"509","author":"Zhang","year":"2017","journal-title":"Virology"}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528818316473?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528818316473?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T04:15:11Z","timestamp":1758514511000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034528818316473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":28,"alternative-id":["S0034528818316473"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2019.01.025","relation":{},"ISSN":["0034-5288"],"issn-type":[{"value":"0034-5288","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The 3D8 single chain variable fragment protein suppress infectious bronchitis virus transmission in the transgenic chickens","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2019.01.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}