{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T08:35:32Z","timestamp":1794558932433,"version":"4.9.1"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003074","name":"Agencia Nacional De Promoci\u00f3n Cient\u00edfica Y Tecnol\u00f3gica","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003074","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006682","name":"Consejo de Investigaci\u00f3n, Universidad Nacional de Salta","doi-asserted-by":"publisher","award":["PIUNT-\/D645-1"],"award-info":[{"award-number":["PIUNT-\/D645-1"]}],"id":[{"id":"10.13039\/501100006682","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007482","name":"Universidad Nacional de Tucum\u00e1n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007482","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.rvsc.2021.11.007","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T16:40:59Z","timestamp":1637340059000},"page":"15-23","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"special_numbering":"C","title":["Bacterial communities from vagina of dairy healthy heifers and cows with impaired reproductive performance"],"prefix":"10.1016","volume":"142","author":[{"given":"Candelaria Gonzalez","family":"Moreno","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Torres","family":"Luque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klibs N.","family":"Galv\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda C.","family":"Otero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rvsc.2021.11.007_bb0005","unstructured":"AHVLA Disease Surveillance Report-April, 2014. Helcococcus ovis: Potential Novel Cause of Bovine Abortion. https:\/\/ www.gov.uk\/government\/uploads\/system\/uploads\/."},{"issue":"10","key":"10.1016\/j.rvsc.2021.11.007_bb0010","doi-asserted-by":"crossref","first-page":"4298","DOI":"10.1093\/jas\/skz210","article-title":"Uterine and vaginal bacterial community diversity prior to artificial insemination between pregnant and non-pregnant postpartum cows. Amer Soc of","volume":"97","author":"Ault","year":"2019","journal-title":"Anim. Sci."},{"issue":"10","key":"10.1016\/j.rvsc.2021.11.007_bb0015","doi-asserted-by":"crossref","first-page":"4305","DOI":"10.1093\/jas\/skz212","article-title":"Bacterial taxonomic composition of the postpartum cow uterus and vagina prior to artificial insemination","volume":"97","author":"Ault","year":"2019","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0020","first-page":"177","article-title":"White side test: a simple and rapid test for evaluation of nonspecific bacterial genital infections of repeat breeding cattle","volume":"5","author":"Bhat","year":"2014","journal-title":"Vet. Res. Forum."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0025","doi-asserted-by":"crossref","first-page":"3850","DOI":"10.3168\/jds.2016-12058","article-title":"Genetic and functional analysis of the bovine uterine microbiota. Part I: Metritis versus healthy cows","volume":"100","author":"Bicalho","year":"2017","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3168\/jds.2016-11623","article-title":"Dynamics of the microbiota found in the vaginas of dairy cows during the transition period: associations with uterine diseases and reproductive outcome","volume":"100","author":"Bicalho","year":"2017","journal-title":"J. Dairy Sci."},{"issue":"2","key":"10.1016\/j.rvsc.2021.11.007_bb0035","first-page":"57","article-title":"Quality-filtering vastly improves diversity estimates from Illumina amplicon sequencing","volume":"10","author":"Bokulich","year":"2013","journal-title":"HHS Public Access"},{"issue":"2","key":"10.1016\/j.rvsc.2021.11.007_bib251","first-page":"147","article-title":"Effect of reproductive disorders and parity on repeat breeder status and culling of dairy cows in Quebec","volume":"75","author":"Bonneville-H\u00e9bert","year":"2011","journal-title":"Can. J. Vet. Res."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0045","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1038\/ismej.2012.8","article-title":"Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms","volume":"6","author":"Caporaso","year":"2012","journal-title":"ISME J."},{"issue":"3","key":"10.1016\/j.rvsc.2021.11.007_bb0050","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1038\/s41596-019-0264-1","article-title":"Using MicrobiomeAnalyst for comprehensive statistical, functional, and meta-analysis of microbiome data","volume":"15","author":"Chong","year":"2020","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0055","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.3389\/fmicb.2017.01047","article-title":"Vaginal and uterine bacterial communities in postpartum lactating cows","volume":"8","author":"Clemmons","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0060","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1080\/00480169.2019.1623733","article-title":"Association of Ureaplasma diversum with reproductive disease in cattle","volume":"67","author":"Diaz","year":"2019","journal-title":"N. Z. Vet. J."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0065","doi-asserted-by":"crossref","first-page":"11060","DOI":"10.1073\/pnas.1502875112","article-title":"Temporal and spatial variation of the human microbiota during pregnancy","volume":"112","author":"Digiulio","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0070","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1093\/bioinformatics\/btq461","article-title":"Search and clustering orders of magnitude faster than BLAST","volume":"26","author":"Edgar","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.rvsc.2021.11.007_bb0075","first-page":"459","article-title":"A body condition scoring chart of Holstein dairy cows","volume":"90","author":"Edmonson","year":"1989","journal-title":"Anim. Physiol. Anim. Nutr."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0080","doi-asserted-by":"crossref","first-page":"505","DOI":"10.3201\/eid1003.020592","article-title":"Bovine necrotic vulvovaginitis associated with Porphyromonas levii","volume":"10","author":"Elad","year":"2004","journal-title":"Emerg. Infect. Dis."},{"issue":"4","key":"10.1016\/j.rvsc.2021.11.007_bb0085","doi-asserted-by":"crossref","first-page":"3439","DOI":"10.3168\/jds.2018-15783","article-title":"Effect of pegbovigrastim administration on the microbiome found in the vagina of cows postpartum","volume":"102","author":"Galv\u00e3o","year":"2019","journal-title":"J. Dairy Sci."},{"issue":"18","key":"10.1016\/j.rvsc.2021.11.007_bb0090","doi-asserted-by":"crossref","DOI":"10.1128\/AEM.01066-20","article-title":"Effect of chitosan microparticles on the uterine microbiome of dairy cows with Metritis","volume":"86","author":"Galv\u00e3o","year":"2020","journal-title":"Appl. Environ. Microbiol."},{"issue":"4","key":"10.1016\/j.rvsc.2021.11.007_bb0095","first-page":"1115","article-title":"A common vaginal microbiota composition among breeds of Bos taurus indicus (Gyr and Nellore). Braz","volume":"50","author":"Giannattasio-Ferraz","year":"2019","journal-title":"J. Microbiol."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0100","doi-asserted-by":"crossref","first-page":"243","DOI":"10.4056\/sigs.1433550","article-title":"Meeting report: the terabase metagenomics workshop and the vision of an earth microbiome project","volume":"3","author":"Gilbert","year":"2010","journal-title":"Stand. Genomic Sci."},{"issue":"6","key":"10.1016\/j.rvsc.2021.11.007_bb0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0228294","article-title":"Characterization of native Escherichia coli populations from bovine vagina of healthy heifers and cows with postpartum uterine disease","volume":"15","author":"Gonzalez Moreno","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.rvsc.2021.11.007_bb0110","first-page":"1","article-title":"Past: paleontological statistics software package for education and data analysis","volume":"4","author":"Hammer","year":"2001","journal-title":"Palaeontol. Electron."},{"issue":"4","key":"10.1016\/j.rvsc.2021.11.007_bb0115","article-title":"An advanced understanding of uterine microbial ecology associated with Metritis in dairy cows. Genomics","volume":"16","author":"Jeon","year":"2018","journal-title":"Inform."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0120","doi-asserted-by":"crossref","first-page":"6324","DOI":"10.1128\/AEM.01753-15","article-title":"Uterine microbiota progression from calving until establishment of Metritis in dairy cows","volume":"81","author":"Jeon","year":"2015","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0125","first-page":"5(1)109","article-title":"Blood as a route of transmission of uterine pathogens from the gut to the uterus in cows","volume":"25","author":"Jeon","year":"2017","journal-title":"Microbiome."},{"issue":"3","key":"10.1016\/j.rvsc.2021.11.007_bb0130","doi-asserted-by":"crossref","first-page":"41","DOI":"10.3314\/mmj.18-00004","article-title":"Next-generation sequencing analysis of bacterial flora in bovine Prototheca Mastitic Milk","volume":"59","author":"Kano","year":"2018","journal-title":"Med Mycol J."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0135","first-page":"807","article-title":"Fertility status of Hariana cows","volume":"86","author":"Kumar","year":"2009","journal-title":"Indian Vet. J."},{"issue":"11","key":"10.1016\/j.rvsc.2021.11.007_bb0140","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0143294","article-title":"Vaginal microbiome characterization of Nellore cattle using metagenomic analysis","volume":"10","author":"Laguardia-Nascimento","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.rvsc.2021.11.007_bb0145","doi-asserted-by":"crossref","first-page":"8228","DOI":"10.1128\/AEM.71.12.8228-8235.2005","article-title":"UniFrac: a new phylogenetic method for comparing microbial communities","volume":"71","author":"Lozupone","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"issue":"3\u20134","key":"10.1016\/j.rvsc.2021.11.007_bb0150","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.vetmic.2012.04.033","article-title":"Investigation of postpartum dairy cows\u2019 uterine microbial diversity using metagenomic pyrosequencing of the 16S rRNA gene","volume":"159","author":"Machado","year":"2012","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0155","doi-asserted-by":"crossref","first-page":"6048","DOI":"10.3168\/jds.2014-8862","article-title":"Consequences and economics of metritis in Iranian Holstein dairy farms","volume":"98","author":"Mahnani","year":"2015","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0160","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1038\/ismej.2011.139","article-title":"An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea","volume":"6","author":"McDonald","year":"2012","journal-title":"ISME J."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0165","first-page":"629","article-title":"Vaginal innate immunity alteration during pregnancy and its impact on pregnancy outcomes. Exp rev","volume":"6","author":"Mendez-Figueroa","year":"2011","journal-title":"Obstet. Gynecol."},{"issue":"6","key":"10.1016\/j.rvsc.2021.11.007_bb0170","doi-asserted-by":"crossref","first-page":"skaa178","DOI":"10.1093\/jas\/skaa178","article-title":"Vaginal bacterial community composition and concentrations of estradiol at the time of artificial insemination in Brangus heifers","volume":"98","author":"Messman","year":"2020","journal-title":"J. Anim. Sci."},{"issue":"1","key":"10.1016\/j.rvsc.2021.11.007_bb0175","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0200974","article-title":"Delayed differentiation of vaginal and uterine microbiomes in dairy cows developing postpartum endometritis","volume":"14","author":"Miranda-CasoLuengo","year":"2019","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.rvsc.2021.11.007_bb0180","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/2193-1801-3-91","article-title":"Comparative studies on genital infections and antimicrobial susceptibility patterns of isolates from camels (Camelus dromedarius) and cows (Bos indicus) in Maiduguri, North-Eastern Nigeria","volume":"15","author":"Mshelia","year":"2014","journal-title":"Springer Plus"},{"key":"10.1016\/j.rvsc.2021.11.007_bb0185","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.3389\/fmicb.2018.02379","article-title":"Insights into the bovine milk microbiota in dairy farms with different incidence rates of subclinical mastitis","volume":"9","author":"Pang","year":"2018","journal-title":"Front. Microbiol."},{"issue":"5","key":"10.1016\/j.rvsc.2021.11.007_bb0190","doi-asserted-by":"crossref","first-page":"3120","DOI":"10.3168\/jds.2014-8944","article-title":"Effect of intrauterine infusion of an organic-certified product on uterine health, survival, and fertility of dairy cows with toxic puerperal metritis","volume":"98","author":"Pinedo","year":"2015","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0195","series-title":"QIAamp DNA Mini and Blood Mini Handbook 06\/2012, Valencia, CA, USA","first-page":"26","article-title":"DNA purification from blood or body fluids","author":"Qiagen\u00ae","year":"2012"},{"key":"10.1016\/j.rvsc.2021.11.007_bb0200","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.rvsc.2020.03.027","article-title":"Study of vaginal microbiota of Holstein cows submitted to an estrus synchronization protocol with the use of intravaginal progesterone device","volume":"131","author":"Quadros","year":"2020","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0205","doi-asserted-by":"crossref","first-page":"371","DOI":"10.3389\/fvets.2020.00371","article-title":"Vaginal microbiota changes during estrous cycle in dairy heifers","volume":"7","author":"Quereda","year":"2020","journal-title":"Front Vet. Sci."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0210","doi-asserted-by":"crossref","first-page":"12340","DOI":"10.1038\/s41598-019-48852-4","article-title":"The subgingival microbial community of feline periodontitis and gingivostomatitis: characterization and comparison between diseased and healthy cats","volume":"9","author":"Rodrigues","year":"2019","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.rvsc.2021.11.007_bb0215","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/2049-2618-2-4","article-title":"The composition and stability of the vaginal microbiota of normal pregnant women is different from that of non-pregnant women","volume":"2","author":"Romero","year":"2014","journal-title":"Microbiome."},{"issue":"6","key":"10.1016\/j.rvsc.2021.11.007_bb0220","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1086\/313815","article-title":"Methylobacterium mesophilicum infection: case report and literature review of an unusual opportunistic pathogen","volume":"30","author":"Sanders","year":"2000","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0225","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1530\/rep.0.1230837","article-title":"Influence of uterine bacterial contamination after parturition on ovarian dominant follicle selection and follicle growth and function in cattle","volume":"123","author":"Sheldon","year":"2002","journal-title":"Reproduction."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0230","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1016\/j.theriogenology.2005.08.021","article-title":"Defining postpartum uterine disease in cattle","volume":"65","author":"Sheldon","year":"2006","journal-title":"Theriogenology."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0235","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1095\/biolreprod.109.077370","article-title":"Defining postpartum uterine Disease and the mechanisms of infection and immunity in the female reproductive tract in cattle","volume":"81","author":"Sheldon","year":"2009","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0240","first-page":"31","article-title":"Identification of species of Mycoplasma and Ureaplasma diversum from Argentinian dairy herds","volume":"50","author":"Sosa","year":"2018","journal-title":"Rev. Argent. Microbiol."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0245","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1099\/ijs.0.057307-0","article-title":"Falsiporphyromonas endometrii gen. Nov., sp. nov., isolated from the postpartum bovine uterus, and emended description of the genus Porphyromonas Shah and Collins 1988","volume":"64","author":"Wagener","year":"2014","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"10.1016\/j.rvsc.2021.11.007_bb0250","doi-asserted-by":"crossref","first-page":"11","DOI":"10.4303\/mg\/235571","article-title":"The bacterial community composition of the bovine rumen detected using pyrosequencing of 16S rRNA genes","volume":"1","author":"Wu","year":"2012","journal-title":"Metagenomics."}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528821003271?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528821003271?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T04:23:36Z","timestamp":1758515016000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034528821003271"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":50,"alternative-id":["S0034528821003271"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2021.11.007","relation":{},"ISSN":["0034-5288"],"issn-type":[{"value":"0034-5288","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bacterial communities from vagina of dairy healthy heifers and cows with impaired reproductive performance","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2021.11.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}