{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T09:48:03Z","timestamp":1762076883201,"version":"build-2065373602"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.rvsc.2022.11.007","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T02:24:59Z","timestamp":1668738299000},"page":"37-43","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Cellular immune response after vaccination with Salmonella Gallinarum 9R in laying hens and addition of aflatoxin and absorbent in the feed"],"prefix":"10.1016","volume":"154","author":[{"given":"Abrah\u00e3o","family":"Carvalho Martins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Contreras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thales","family":"Quedi Furian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Apellanis Borges","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Pinheiro do Nascimento","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rvsc.2022.11.007_bb0005","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s12192-021-01204-6","article-title":"Stress and immunity in poultry: light management and nanotechnology as effective immune enhancers to fight stress","volume":"26","author":"Abo-Al-Ela","year":"2021","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0010","doi-asserted-by":"crossref","first-page":"3308","DOI":"10.1016\/j.sjbs.2022.02.007","article-title":"Isolation and partial characterization of Salmonella Gallinarum bacteriophage","volume":"29","author":"Al-Razem","year":"2022","journal-title":"Saudi J. Biol. Sci."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/03079450601113167","article-title":"Salmonella infections: immune and non-immune protection with vaccines","volume":"36","author":"Barrow","year":"2007","journal-title":"Avian Pathol."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/03079457.2010.542575","article-title":"Pullorum disease and fowl typhoid-new thoughts on old diseases: a review","volume":"40","author":"Barrow","year":"2011","journal-title":"Avian Pathol."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0030","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1128\/CMR.16.3.497-516.2003","article-title":"Mycotoxins","volume":"16","author":"Bennett","year":"2003","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0040","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.vetimm.2008.10.295","article-title":"The immunobiology of avian systemic salmonellosis","volume":"128","author":"Chappell","year":"2009","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101651","article-title":"Effects of lactobacillus salivarius supplementation on the growth performance, liver function, meat quality, immune responses and Salmonella Pullorum infection resistance of broilers challenged with aflatoxin B1","volume":"101","author":"Chen","year":"2022","journal-title":"Poult. Sci."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0050","doi-asserted-by":"crossref","first-page":"727","DOI":"10.3382\/ps.2007-00403","article-title":"Aflatoxicosis in chickens (Gallus gallus): an example of hormesis?","volume":"87","author":"Diaz","year":"2008","journal-title":"Poult. Sci."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0055","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1590\/S0103-84782000000100022","article-title":"Classifica\u00e7\u00e3o macrosc\u00f3pica, identifica\u00e7\u00e3o da microbiota f\u00fangica e produ\u00e7\u00e3o de aflatoxinas em h\u00edbridos de milho","volume":"30","author":"Dilkin","year":"2000","journal-title":"Ci\u00eanc. Rural"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0060","series-title":"Mycotoxins - Impact and Management Strategies","article-title":"Aflatoxins: Their toxic effect on poultry and recent advances in their treatment","author":"Ditta","year":"2018"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0065","series-title":"Ressurg\u00eancia do tifo avi\u00e1rio na avicultura industrial brasileira: novos estudos epidemiol\u00f3gicos de uma enfermidade antiga","first-page":"82","author":"Estupinan","year":"2016"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0070","unstructured":"European Council (EC). Directive 2002\/32\/EC - On undesirable substances in animal feed. Accessed Mar. 2022. https:\/\/eur-lex.europa.eu\/LexUriServ\/LexUriServ.do?uri=CONSLEG:2002L0032:20061020:EN:PDF."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0075","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.vetimm.2008.05.012","article-title":"Immunophenotyping of chicken peripheral blood lymphocyte subpopulations: individual variability and repeatability","volume":"125","author":"Fair","year":"2008","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0080","doi-asserted-by":"crossref","first-page":"176","DOI":"10.3390\/toxins11030176","article-title":"Harmful effects and control strategies of aflatoxin B\u2081 produced by aspergillus flavus and aspergillus parasiticus strains on poultry: review","volume":"11","author":"Fouad","year":"2019","journal-title":"Toxins"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0085","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1637\/0005-2086(2002)046[0137:SDOESE]2.0.CO;2","article-title":"Serologic detection of experimental Salmonella Enteritidis infections in laying hens by fluorescence polarization and enzyme immunoassay","volume":"46","author":"Gast","year":"2002","journal-title":"Avian Dis."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0090","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1590\/S0103-84782006000100036","article-title":"Desempenho e plumagem de frangos de corte intoxicados por aflatoxinas","volume":"36","author":"Giacomini","year":"2006","journal-title":"Ci\u00eanc. Rural"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0095","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3390\/vetsci8050071","article-title":"Salmonella Gallinarum in small-scale commercial layer flocks: occurrence, molecular diversity and antibiogram","volume":"8","author":"Haque","year":"2021","journal-title":"Vet. Sci."},{"author":"Hendrix Genetics","key":"10.1016\/j.rvsc.2022.11.007_bb0100"},{"author":"Hendrix Genetics","key":"10.1016\/j.rvsc.2022.11.007_bb0105"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0110","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s13567-018-0560-8","article-title":"Vaccines as alternatives to antibiotics for food producing animals. Part 1: challenges and needs","volume":"49","author":"Hoelzer","year":"2018","journal-title":"Vet. Res."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0115","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1637\/8909-043009-Review.1","article-title":"Clinical aspects of immunosuppression in poultry","volume":"54","author":"Hoerr","year":"2010","journal-title":"Avian Dis."},{"key":"10.1016\/j.rvsc.2022.11.007_bib231","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.vetimm.2009.08.001","article-title":"Flow cytometric characterization of Peyer\u2019s patch and cecal tonsil T lymphocytes in laying hens following challenge with Salmonella enterica serovar Enteritidis","volume":"133","author":"Holt","year":"2010","journal-title":"Vet. Immunol. Immunopathol."},{"year":"2017","series-title":"ISO 6579-1:2017 - Microbiology of the food chain \u2014 Horizontal method for the detection, enumeration and serotyping of Salmonella \u2014 Part 1: Detection of Salmonella spp. 50p","author":"International Organization for Standardization (ISO)","key":"10.1016\/j.rvsc.2022.11.007_bb0120"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0125","doi-asserted-by":"crossref","first-page":"6945","DOI":"10.3390\/ijms16046945","article-title":"Effects of aflatoxin B1 on T-cell subsets and mRNA expression of cytokines in the intestine of broilers","volume":"16","author":"Jiang","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0130","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1128\/CVI.00310-14","article-title":"Evaluation of protective efficacy of live attenuated Salmonella enterica serovar Gallinarum vaccine strains against fowl typhoid in chickens","volume":"21","author":"Laniewski","year":"2014","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0135","doi-asserted-by":"crossref","first-page":"60","DOI":"10.3389\/fcimb.2018.00060","article-title":"Mycotoxin: its impact on gut health and microbiota","volume":"8","author":"Liew","year":"2018","journal-title":"Front. Cell. Infect. Microbiol."},{"year":"1988","series-title":"Portaria MA\/SNAD\/SFA No. 07, de 09\/11\/88 \u2013 publicada no Di\u00e1rio Oficial da Uni\u00e3o de 09 de novembro de 1988 - Se\u00e7\u00e3o 1, p\u00e1gina 21.968","author":"Minist\u00e9rio da Agricultura, Pecu\u00e1ria e Abastecimento (MAPA)","key":"10.1016\/j.rvsc.2022.11.007_bb0140"},{"year":"2011","series-title":"Resolu\u00e7\u00e3o No. 07, de 18\/02\/11 \u2013 publicada no Di\u00e1rio Oficial da Uni\u00e3o de 09 de novembro de 2011 - Se\u00e7\u00e3o 1, p\u00e1gina 72","author":"Minist\u00e9rio da Sa\u00fade (MS)","key":"10.1016\/j.rvsc.2022.11.007_bb0145"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0150","doi-asserted-by":"crossref","first-page":"742","DOI":"10.3390\/agriculture5030742","article-title":"Aflatoxicosis: lessons from toxicity and responses to aflatoxin B1 in poultry","volume":"5","author":"Monson","year":"2015","journal-title":"Agriculture"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0155","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40550-020-00079-2","article-title":"Awareness of mycotoxins and occurrence of aflatoxins in poultry feeds and feed ingredients in selected regions of Uganda","volume":"7","author":"Nakavuma","year":"2020","journal-title":"Food Contaminat."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0160","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1080\/02652030050034037","article-title":"Aflatoxin B1 residues in eggs of laying hens fed a diet containing different levels of the mycotoxin","volume":"17","author":"Oliveira","year":"2000","journal-title":"Food Addit. Contam. Part A"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0165","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1590\/S1516-635X2009000100010","article-title":"Efficacy of several Salmonella vaccination programs against experimental challenge with Salmonella Gallinarum in commercial brown layer and broiler breeder hens","volume":"11","author":"Paiva","year":"2009","journal-title":"Braz. J. Poult. Sci."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0170","doi-asserted-by":"crossref","first-page":"7637","DOI":"10.1016\/j.vaccine.2012.10.020","article-title":"Humoral and cellular immune response generated by different vaccine programs before and after Salmonella Enteritidis challenge in chickens","volume":"30","author":"Penha Filho","year":"2012","journal-title":"Vaccine."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0175","doi-asserted-by":"crossref","first-page":"279","DOI":"10.3382\/japr\/pfx066","article-title":"Vaccines and vaccination against fowl typhoid and pullorum disease: an overview and approaches in developing countries","volume":"27","author":"Revolledo","year":"2018","journal-title":"J. Appl. Poult. Res."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0180","series-title":"XXIV World\u2019s Poultry Congress 5\u20139 August \u2013 2012","article-title":"Current perspectives in avian salmonellosis: Vaccines and immune mechanisms of protection","author":"Revolledo","year":"2012"},{"author":"Sandu","key":"10.1016\/j.rvsc.2022.11.007_bb0185"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0190","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1080\/1745039X.2010.492140","article-title":"Comparative aspects of in vitro proliferation of human and porcine lymphocytes exposed to mycotoxins","volume":"64","author":"Taranu","year":"2010","journal-title":"Arch. Anim. Nutr."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0195","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1080\/00071660600756071","article-title":"Effects of aflatoxin B1 and fumonisin B1 on body weight, antibody titres and histology of broiler chicks","volume":"47","author":"Tessari","year":"2006","journal-title":"Br. Poult. Sci."},{"author":"U.S. Food and Drug Administration","key":"10.1016\/j.rvsc.2022.11.007_bb0200"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0205","doi-asserted-by":"crossref","first-page":"774","DOI":"10.4315\/0362-028X-73.4.774","article-title":"Salmonella in chicken: current and developing strategies to reduce contamination at farm level","volume":"73","author":"Vandeplas","year":"2010","journal-title":"J. Food Prot."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0210","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.3389\/fmicb.2018.01718","article-title":"Identification and discrimination of Salmonella enterica serovar Gallinarum biovars Pullorum and Gallinarum based on a one-step multiplex PCR assay","volume":"9","author":"Xiong","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0215","doi-asserted-by":"crossref","first-page":"566","DOI":"10.3390\/toxins3060566","article-title":"Aflatoxin B(1) in affecting broiler's performance, immunity, and gastrointestinal tract: a review of history and contemporary issues","volume":"3","author":"Yunus","year":"2011","journal-title":"Toxins"},{"key":"10.1016\/j.rvsc.2022.11.007_bb0220","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1590\/s0100-736x2017001100005","article-title":"In vivo amelioration of aflatoxin B1 in broiler chicks by magnetic carbon nanocomposite","volume":"37","author":"Zafar","year":"2017","journal-title":"Pesqui. Vet. Bras."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0225","article-title":"Evaluation of safety and protective efficacy of a waaJ and spiC double deletion Korean epidemic strain of Salmonella enterica serovar Gallinarum","volume":"16","author":"Zhang","year":"2021","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.rvsc.2022.11.007_bb0230","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1590\/1516-635x1603307-312","article-title":"In-vitro cytotoxicity of aflatoxin B1 to broiler lymphocytes of broiler chickens","volume":"16","author":"Zimmermann","year":"2014","journal-title":"Braz. J. Poult. Sci."}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528822003770?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528822003770?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T04:28:31Z","timestamp":1758515311000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034528822003770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":45,"alternative-id":["S0034528822003770"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2022.11.007","relation":{},"ISSN":["0034-5288"],"issn-type":[{"type":"print","value":"0034-5288"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cellular immune response after vaccination with Salmonella Gallinarum 9R in laying hens and addition of aflatoxin and absorbent in the feed","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2022.11.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}