{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T02:10:00Z","timestamp":1758593400330,"version":"3.44.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.rvsc.2023.03.017","type":"journal-article","created":{"date-parts":[[2023,3,25]],"date-time":"2023-03-25T02:54:06Z","timestamp":1679712846000},"page":"124-133","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Characterization of humoral and cellular immune responses elicited by reduced doses of Brucella abortus S19 (calfhood) vaccine in cattle calves of India"],"prefix":"10.1016","volume":"158","author":[{"given":"Rajeswari","family":"Shome","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sreenivasulu","family":"Kilari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amol","family":"Sahare","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Triveni","family":"Kalleshamurthy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bibek Ranjan","family":"Shome","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somy","family":"Skariah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jagadish","family":"Hiremath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyoti","family":"Misri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Habibar","family":"Rahman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rvsc.2023.03.017_bb0005","doi-asserted-by":"crossref","first-page":"867","DOI":"10.20506\/rst.19.3.1258","article-title":"Immune response of buffaloes to vaccination with Brucella abortus strain 19","volume":"19","author":"Afzal","year":"2000","journal-title":"Rev. Sci. Tech. Off Int. \u00c9pizoot."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0010","first-page":"58","article-title":"Reduced dose whole herd vaccination against brucellosis","volume":"18","author":"Ahmad","year":"1998","journal-title":"Pak. Vet. J."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0015","doi-asserted-by":"crossref","first-page":"30","DOI":"10.3389\/fcimb.2016.00030","article-title":"Establishment of chronic infection: Brucella\u2019s stealth strategy","volume":"6","author":"Ahmed","year":"2016","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0020","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1751-0813.1980.tb09561.x","article-title":"Vaccination of pregnant cows with low doses of Brucella abortus strain 19 vaccine","volume":"56","author":"Alton","year":"1980","journal-title":"Aust. Vet. J."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0025","series-title":"Techniques for the Brucellosis Laboratory","first-page":"13","volume":"147","author":"Alton","year":"1988"},{"key":"10.1016\/j.rvsc.2023.03.017_bb0030","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3329\/bvet.v33i1.33311","article-title":"Immune response of cattle to vaccination with Brucella abortus strain 19 in India","volume":"33","author":"Baksi","year":"2016","journal-title":"Bangladesh Vet."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0035","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/0007-1935(87)90025-X","article-title":"Persistent serological titres following reduced dose Brucella abortus strain 19 vaccination","volume":"143","author":"Beckett","year":"1987","journal-title":"Br. Vet. J."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0040","first-page":"589494","article-title":"Host susceptibility to Brucella abortus infection is more pronounced in IFN-\u03b3 knockout than IL-12\/\u03b22-microglobulin double-deficient mice","author":"Brand\u00e3o","year":"2012","journal-title":"Clin. Dev. Immunol."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0045","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1002\/jlb.56.2.174","article-title":"Differentiated U937 cells exhibit increased bactericidal activity upon LPS activation and discriminate between virulent and avirulent listeria and Brucella species","volume":"56","author":"Caron","year":"1994","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0050","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/0378-1135(85)90065-3","article-title":"Effects of challenge dose on the clinical and immune responses of cattle vaccinated with reduced doses of Brucella abortus strain 19","volume":"10","author":"Confer","year":"1985","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0055","doi-asserted-by":"crossref","DOI":"10.7589\/0090-3558-38.1.18","article-title":"Brucella abortus strain RB51 vaccination in elk efficacy of reduced dosage","volume":"38","author":"Cook","year":"2002","journal-title":"J. Wildl. Dis."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0060","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0092-1157(80)80033-3","article-title":"Brucella abortus (Strain 19) vaccine: (a) Determination of the minimum protective dose in cattle; (b) The effect of vaccinating calves previously inoculated with anti-Brucella abortus serum","volume":"8","author":"Davies","year":"1980","journal-title":"J. Biol. Stand."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0065","doi-asserted-by":"crossref","first-page":"258","DOI":"10.7589\/0090-3558-27.2.258","article-title":"Brucella abortus in bison. II. Evaluation of strain 19 vaccination of pregnant cows","volume":"27","author":"Davies","year":"1991","journal-title":"J. Wildl. Dis."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0070","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.vetimm.2005.02.023","article-title":"Evaluation of cell mediated immune response and bacterial clearance in 6-10 months old water buffaloes (Bubalus bubalis) experimentally vaccinated with four dosages of commercial Brucella abortus St. RB-51 vaccine","volume":"106","author":"Diptee","year":"2005","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0075","doi-asserted-by":"crossref","first-page":"0136696","DOI":"10.1371\/journal.pone.0136696","article-title":"Immune response of calves vaccinated with Brucella abortus S19 or RB51 and revaccinated with RB51","volume":"10","author":"Dorneles","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.rvsc.2023.03.017_bb0080","doi-asserted-by":"crossref","first-page":"893","DOI":"10.20506\/rst.22.3.1444","article-title":"The immune response of Guinea pigs and buffalo calves to the locally prepared Brucella abortus strain 19 vaccine","volume":"22","author":"Jamal","year":"2003","journal-title":"Rev. Sci. Tech. Off. Int. \u00c9pizoot."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0085","first-page":"136","article-title":"Safety and efficacy of reduced dose Brucella abortus strain-19 vaccine in non-pregnant zebu cattle (Bos indicus) heifers","volume":"86","author":"Kumar","year":"2016","journal-title":"Ind. J. Anim. Sci."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0090","first-page":"147","article-title":"Production of interferon gamma in whole blood cultures in response to Brucella abortus antigens in RB51-vaccinated cattle","volume":"45","author":"Leal","year":"2007","journal-title":"Tec. Pecu. Mex."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0095","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.vetimm.2015.04.008","article-title":"Immune responses and protection induced by Brucella suis S2 bacterial ghosts in mice","volume":"166","author":"Liua","year":"2015","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0100","doi-asserted-by":"crossref","first-page":"16","DOI":"10.2460\/ajvr.1998.59.08.1016","article-title":"Field study of vaccination of cattle with Brucella abortus strains RB51 and 19 under high and low disease prevalence","volume":"59","author":"Lord","year":"1998","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1051\/vetres:2003037","article-title":"Rough vaccines in animal brucellosis: structural and genetic basis and present status","volume":"35","author":"Moriyon","year":"2004","journal-title":"Vet. Res."},{"year":"2009","series-title":"Immune Response of Buffaloes against Brucella abortus Vaccines. Doctoral Thesis Submitted to the Department of Biochemistry, Faculty of Sciences","author":"Munir","key":"10.1016\/j.rvsc.2023.03.017_bb0110"},{"key":"10.1016\/j.rvsc.2023.03.017_bb0115","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1574-695X.2001.tb00536.x","article-title":"Immune control of Brucella abortus 2308 infections in BALB\/c mice","volume":"32","author":"Murphy","year":"2001","journal-title":"FEMS Immunol. Med. Microbiol."},{"author":"National Dairy Development Board (NDDB)","key":"10.1016\/j.rvsc.2023.03.017_bb0120"},{"key":"10.1016\/j.rvsc.2023.03.017_bb0125","first-page":"147","article-title":"Vaccination against Brucella","volume":"13","author":"Nicoletti","year":"1990","journal-title":"Adv. Biotechnol. Process."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0130","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1292\/jvms.70.197","article-title":"Cytokine responses in camels (Camelus bactrianus) vaccinated with Brucella abortus strain 19 vaccine","volume":"70","author":"Odbileg","year":"2008","journal-title":"J. Vet. Med. Sci."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0135","first-page":"115","article-title":"Resolutions adopted by the world assembly of delegates of the OIE during its 84th general session 22\u201327 May 2016","volume":"26","author":"Office International des Epizooties (OIE)","year":"2016","journal-title":"Resolution"},{"year":"2018","series-title":"Terrestrial Manual. Chapter 3.1.4. Brucellosis (Brucella abortus, B. melitensis and B. suis)","author":"Office International des Epizooties (OIE)","key":"10.1016\/j.rvsc.2023.03.017_bb0140"},{"key":"10.1016\/j.rvsc.2023.03.017_bb0145","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1586\/14760584.4.6.915","article-title":"Essential role of vaccines in brucellosis control and eradication programs for livestock","volume":"4","author":"Olsen","year":"2005","journal-title":"Expert. Rev. Vaccines"},{"key":"10.1016\/j.rvsc.2023.03.017_bb0150","doi-asserted-by":"crossref","first-page":"8576","DOI":"10.4049\/jimmunol.181.12.8576","article-title":"IL-12 produced by dendritic cells augments CD8+ T cell activation through the production of the chemokines CCL1 and CCL17","volume":"181","author":"Henry","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0155","series-title":"Veterinary Medicine, Textbook of the Diseases of Cattle, Sheep, Pigs, Goats and Horses","first-page":"963","author":"Radostits","year":"2007"},{"key":"10.1016\/j.rvsc.2023.03.017_bb0160","first-page":"7","article-title":"Safety of Brucella abortus strain 19 reduced dose (s\/c) vaccine in pregnant cattle","volume":"9","author":"Raghunandan","year":"2018","journal-title":"Ann. Biol. Res."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2022.e08937","article-title":"Studies on intra-ocular vaccination of adult cattle with reduced dose Brucella abortus strain-19 vaccine","volume":"8","author":"Saidu","year":"2022","journal-title":"Heliyon"},{"key":"10.1016\/j.rvsc.2023.03.017_bb0170","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1016\/S0264-410X(98)00063-2","article-title":"The defect in the metabolism of erythritol of the Brucella abortus B19 vaccine strain is unrelated with its attenuated virulence in mice","volume":"16","author":"Sangari","year":"1998","journal-title":"Vaccine"},{"key":"10.1016\/j.rvsc.2023.03.017_bb0175","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S0378-1135(02)00255-9","article-title":"Brucellosis vaccines: past, present and future","volume":"90","author":"Schurig","year":"2002","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0180","doi-asserted-by":"crossref","first-page":"7070","DOI":"10.1016\/j.vaccine.2020.09.010","article-title":"Evaluation of the immune responses against reduced doses of Brucella abortus S19 (calfhood) vaccine in water buffaloes (Bubalus bubalis), India","volume":"38","author":"Shome","year":"2020","journal-title":"Vaccine"},{"key":"10.1016\/j.rvsc.2023.03.017_bb0185","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.4102\/jsava.v89i0.1527","article-title":"Immunological response to Brucella abortus strain 19 vaccination of cattle in a communal area in South Africa","volume":"89","author":"Simpson","year":"2018","journal-title":"J. S. Afr. Vet. Assoc."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0190","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.prevetmed.2015.03.013","article-title":"Economic losses occurring due to brucellosis in Indian livestock populations","volume":"119","author":"Singh","year":"2015","journal-title":"Prev. Vet. Med."},{"year":"1998","series-title":"Brucellosis eradication: uniform methods and rules","author":"USDA-APHIS","key":"10.1016\/j.rvsc.2023.03.017_bb0195"},{"key":"10.1016\/j.rvsc.2023.03.017_bb0200","first-page":"89","article-title":"Occupational cases of Brucella infection after inoculation of B 19 vaccine","volume":"43","author":"Vincent","year":"1970","journal-title":"Bull. Acad. Vet. Fr."},{"key":"10.1016\/j.rvsc.2023.03.017_bb0205","first-page":"656","article-title":"Application of a serum test to differentiate diagnosis of typhoid and Malta fever","volume":"1","author":"Wright","year":"1897","journal-title":"Lancet"},{"key":"10.1016\/j.rvsc.2023.03.017_bb0210","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.5713\/ajas.2008.70746","article-title":"Genetic variation and divergence among swamp buffalo, river buffalo and cattle: a microsatellite survey on five populations in China","volume":"21","author":"Zhang","year":"2008","journal-title":"Asian-Aust. J. Anim. Sci."}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528823000899?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528823000899?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T04:30:05Z","timestamp":1758515405000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034528823000899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":42,"alternative-id":["S0034528823000899"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2023.03.017","relation":{},"ISSN":["0034-5288"],"issn-type":[{"type":"print","value":"0034-5288"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of humoral and cellular immune responses elicited by reduced doses of Brucella abortus S19 (calfhood) vaccine in cattle calves of India","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2023.03.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}