{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T09:12:42Z","timestamp":1785143562698,"version":"3.55.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100008959","name":"Hunan Agricultural University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008959","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFD1301200"],"award-info":[{"award-number":["2023YFD1301200"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.rvsc.2026.106191","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T23:13:48Z","timestamp":1776467628000},"page":"106191","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Dietary supplementation of Radix Isatidis polysaccharides improves meat quality in broilers by regulating lipid metabolism, antioxidant defense, and the gut-muscle axis"],"prefix":"10.1016","volume":"206","author":[{"given":"Wei","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbin","family":"Ouyang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibo","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panpan","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pingping","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianguo","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meirong","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sundus","family":"Javed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rvsc.2026.106191_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.104295","article-title":"Sustainable poultry farming practices: a critical review of current strategies and future prospects","volume":"103","author":"Bist","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.rvsc.2026.106191_bb0010","doi-asserted-by":"crossref","first-page":"503","DOI":"10.3390\/ani13030503","article-title":"Effects of dietary supplementation of chinese yam polysaccharide on carcass composition, meat quality, and antioxidant capacity in broilers","volume":"13","author":"Chang","year":"2023","journal-title":"Animals"},{"key":"10.1016\/j.rvsc.2026.106191_bb0015","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1177\/1534735410387420","article-title":"Isatis indigotica induces hepatocellular cancer cell death via caspase-independent apoptosis-inducing factor translocation apoptotic pathway in vitro and in vivo","volume":"10","author":"Chung","year":"2011","journal-title":"Integr. Cancer Ther."},{"key":"10.1016\/j.rvsc.2026.106191_bb0020","series-title":"Chinese Pharmacopoeia (2020 Edition)","volume":"Vol. I","author":"Commission","year":"2020"},{"key":"10.1016\/j.rvsc.2026.106191_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.139988","article-title":"Alleviation of lipid metabolic dysfunction through regulation of intestinal bacteriophages and bacteria by green tea polyphenols in Ob\/Ob mice","volume":"456","author":"Dong","year":"2024","journal-title":"Food Chem."},{"key":"10.1016\/j.rvsc.2026.106191_bb0030","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.3390\/foods12071479","article-title":"Effects of chinese yam polysaccharide on intramuscular fat and fatty acid composition in breast and thigh muscles of broilers","volume":"12","author":"Guo","year":"2023","journal-title":"Foods"},{"key":"10.1016\/j.rvsc.2026.106191_bb0035","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1078\/09447110260571661","article-title":"Studies on the antinociceptive, anti-inflammatory and antipyretic effects of Isatis indigotica root","volume":"9","author":"Ho","year":"2002","journal-title":"Phytomedicine"},{"key":"10.1016\/j.rvsc.2026.106191_bb0040","doi-asserted-by":"crossref","DOI":"10.1093\/jas\/skad267","article-title":"Omega-3 meat enrichment and L-FABP, PPARA, and LPL genes expression are modified by the level and period of tuna oil supplementation in slow-growing chickens","volume":"101","author":"Khosinklang","year":"2023","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.rvsc.2026.106191_bb0045","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.5713\/ajas.18.0522","article-title":"The impact of dietary linseed oil and pomegranate peel extract on broiler growth, carcass traits, serum lipid profile, and meat fatty acid, phenol, and flavonoid contents","volume":"32","author":"Kishawy","year":"2019","journal-title":"Asian Australas. J. Anim. Sci."},{"key":"10.1016\/j.rvsc.2026.106191_bb0050","article-title":"Effects of herbal dregs supplementation of Salvia miltiorrhiza and isatidis radix residues improved production performance and gut microbiota abundance in late-phase laying hens","volume":"11","author":"Li","year":"2024","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.rvsc.2026.106191_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.169919","article-title":"Di-2-ethylhexyl phthalate disrupts hepatic lipid metabolism in obese mice by activating the LXR\/SREBP-1c and PPAR-\u03b1 signaling pathways","volume":"914","author":"Liang","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.rvsc.2026.106191_bb0060","article-title":"Seabuckthorn polysaccharide combined with astragalus polysaccharide ameliorate alcoholic fatty liver by regulating intestinal flora","volume":"13","author":"Liu","year":"2022","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.rvsc.2026.106191_bb0065","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.ijbiomac.2019.09.168","article-title":"The antioxidant activities of balsam pear polysaccharide","volume":"142","author":"Mei","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.rvsc.2026.106191_bb0070","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1038\/s41569-021-00569-6","article-title":"PPAR control of metabolism and cardiovascular functions","volume":"18","author":"Montaigne","year":"2021","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.rvsc.2026.106191_bb0075","doi-asserted-by":"crossref","DOI":"10.1155\/2023\/3220344","article-title":"Omega-6: its pharmacology, effect on the broiler production, and health","volume":"2023","author":"Nur Mahendra","year":"2023","journal-title":"Vet. Med. Int."},{"key":"10.1016\/j.rvsc.2026.106191_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.rvsc.2023.105080","article-title":"Effects of dietary supplementation with Radix Isatidis polysaccharide on egg quality, immune function, and intestinal health in hens","volume":"166","author":"Shi","year":"2024","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.rvsc.2026.106191_bb0085","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s10753-009-9164-9","article-title":"The anti-inflammatory effects of a methanolic extract from Radix Isatidis in murine macrophages and mice","volume":"33","author":"Shin","year":"2010","journal-title":"Inflammation"},{"key":"10.1016\/j.rvsc.2026.106191_bb0090","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1111\/are.13472","article-title":"Effects of isatis root polysaccharide on non-specific immune responses and nutritive indices in obscure pufferfish, Takifugu obscurus","volume":"49","author":"Song","year":"2018","journal-title":"Aquac. Res."},{"key":"10.1016\/j.rvsc.2026.106191_bb0095","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.ijbiomac.2016.12.010","article-title":"Characterization, antioxidant activity and immunomodulatory activity of polysaccharides from the swollen culms of Zizania latifolia","volume":"95","author":"Wang","year":"2017","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.rvsc.2026.106191_bb0100","doi-asserted-by":"crossref","first-page":"3489","DOI":"10.3382\/ps\/pey220","article-title":"Effect of dietary astragalus membranaceus polysaccharide on the growth performance and immunity of juvenile broilers","volume":"97","author":"Wu","year":"2018","journal-title":"Poult. Sci."},{"key":"10.1016\/j.rvsc.2026.106191_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.102534","article-title":"Radix Isatidis polysaccharide (RIP) resists the infection of QX-type infectious bronchitis virus via the MDA5\/TLR3\/IRF7 signaling pathway","volume":"102","author":"Xiang","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.rvsc.2026.106191_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112566","article-title":"Artemisia ordosica polysaccharide alleviated lipopolysaccharide-induced oxidative stress of broilers via Nrf2\/Keap1 and TLR4\/NF-\u03baB pathway","volume":"223","author":"Xing","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.rvsc.2026.106191_bb0115","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.ijbiomac.2015.05.054","article-title":"Protective effects of Ginkgo biloba leaf polysaccharide on nonalcoholic fatty liver disease and its mechanisms","volume":"80","author":"Yan","year":"2015","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.rvsc.2026.106191_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.103150","article-title":"Effects of dietary incorporation of Radix rehmanniae praeparata polysaccharide on growth performance, digestive physiology, blood metabolites, meat quality, and tibia characteristics in broiler chickens","volume":"102","author":"Yang","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.rvsc.2026.106191_bb0125","article-title":"The impact of dietary supplementation of polysaccharide derived from polygonatum sibiricum on growth, antioxidant capacity, meat quality, digestive physiology, and gut microbiota in broiler chickens","volume":"103","author":"Yang","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.rvsc.2026.106191_bb0130","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/s40104-024-01060-1","article-title":"Astragalus polysaccharides-induced gut microbiota play a predominant role in enhancing of intestinal barrier function of broiler chickens","volume":"15","author":"Yang","year":"2024","journal-title":"J. anim. sci. biotechnol."},{"key":"10.1016\/j.rvsc.2026.106191_bb0135","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2023.1129904","article-title":"Bifidobacterium-derived short-chain fatty acids and indole compounds attenuate nonalcoholic fatty liver disease by modulating gut-liver axis","volume":"14","author":"Yoon","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.rvsc.2026.106191_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2019.06.010","article-title":"Immunoenhancement effects of pentadecapeptide derived from Cyclina sinensis on immune-deficient mice induced by Cyclophosphamide","volume":"60","author":"Yu","year":"2019","journal-title":"J. Funct. Foods"},{"key":"10.1016\/j.rvsc.2026.106191_bb0145","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1093\/jpp\/rgac027","article-title":"Protective effects of radix isatidis polysaccharide ameliorates obesity via promotion AMPK pathway in high-fat-diet-induced obese rats and 3T3-L1 adipocyte cells","volume":"74","author":"Yuan","year":"2022","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.rvsc.2026.106191_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.102068","article-title":"Effect of Gan Cao (Glycyrrhiza uralensis fisch) polysaccharide on growth performance, immune function, and gut microflora of broiler chickens","volume":"101","author":"Zhang","year":"2022","journal-title":"Poult. Sci."},{"key":"10.1016\/j.rvsc.2026.106191_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.fochx.2024.101406","article-title":"Dietary salidroside supplementation improves meat quality and antioxidant capacity and regulates lipid metabolism in broilers","volume":"22","author":"Zhang","year":"2024","journal-title":"Food Chem. X"}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003452882600144X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003452882600144X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T08:44:40Z","timestamp":1785141880000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S003452882600144X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":31,"alternative-id":["S003452882600144X"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2026.106191","relation":{},"ISSN":["0034-5288"],"issn-type":[{"value":"0034-5288","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dietary supplementation of Radix Isatidis polysaccharides improves meat quality in broilers by regulating lipid metabolism, antioxidant defense, and the gut-muscle axis","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2026.106191","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106191"}}