{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T14:19:00Z","timestamp":1788445140680,"version":"build-2803163510"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24 K01930"],"award-info":[{"award-number":["24 K01930"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP17H04661"],"award-info":[{"award-number":["JP17H04661"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015060","name":"Nagasaki University","doi-asserted-by":"publisher","award":["2023-Kyoten-02"],"award-info":[{"award-number":["2023-Kyoten-02"]}],"id":[{"id":"10.13039\/100015060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015060","name":"Nagasaki University","doi-asserted-by":"publisher","award":["2025-Kyoten-03"],"award-info":[{"award-number":["2025-Kyoten-03"]}],"id":[{"id":"10.13039\/100015060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015060","name":"Nagasaki University","doi-asserted-by":"publisher","award":["2022-Kyoten-03"],"award-info":[{"award-number":["2022-Kyoten-03"]}],"id":[{"id":"10.13039\/100015060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015060","name":"Nagasaki University","doi-asserted-by":"publisher","award":["2024-Kyoten-05"],"award-info":[{"award-number":["2024-Kyoten-05"]}],"id":[{"id":"10.13039\/100015060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007172","name":"National Agriculture and Food Research Organization","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007172","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Veterinary Science"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.rvsc.2026.106299","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T23:28:12Z","timestamp":1781566092000},"page":"106299","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Infectious stability of animal gastrointestinal coronaviruses in fasted-state simulated gastric fluid"],"prefix":"10.1016","volume":"210","author":[{"given":"Weiyin","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Shimoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Hayasaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rvsc.2026.106299_bb0005","series-title":"Encycl. Virol.","first-page":"193","article-title":"Coronaviruses: general features (Coronaviridae)","author":"Britton","year":"2019"},{"key":"10.1016\/j.rvsc.2026.106299_bb0010","doi-asserted-by":"crossref","first-page":"10556","DOI":"10.1128\/JVI.78.19.10556-10565.2004","article-title":"The raft-promoting property of Virion-associated cholesterol, but not the presence of Virion-associated Brij 98 rafts, is a determinant of human immunodeficiency virus type 1 infectivity","volume":"78","author":"Campbell","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.rvsc.2026.106299_bb0015","series-title":"Encycl. Virol.","first-page":"549","article-title":"Coronaviruses: general features","author":"Cavanagh","year":"2008"},{"key":"10.1016\/j.rvsc.2026.106299_bb0020","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1079\/BJN19850113","article-title":"The development of acid and pepsin (EC 3. 4. 23. 1) Secretory capacity in the pig; the effects of age and weaning","volume":"54","author":"Cranwell","year":"1985","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.rvsc.2026.106299_bb0025","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1038\/s42003-025-08514-w","article-title":"Inactivation of SARS-CoV-2 at acidic pH is driven by partial unfolding of spike","volume":"8","author":"Glas","year":"2025","journal-title":"Commun. Biol."},{"key":"10.1016\/j.rvsc.2026.106299_bb0030","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s41182-023-00573-1","article-title":"pH-dependent virucidal effects of weak acids against pathogenic viruses","volume":"52","author":"Hu","year":"2024","journal-title":"Trop. Med. Heal."},{"key":"10.1016\/j.rvsc.2026.106299_bb0035","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2021.637885","article-title":"Acid pH increases SARS-CoV-2 infection and the risk of death by COVID-19","volume":"8","author":"Jimenez","year":"2021","journal-title":"Front. Med."},{"key":"10.1016\/j.rvsc.2026.106299_bb0040","doi-asserted-by":"crossref","first-page":"4734","DOI":"10.3390\/ijms22094734","article-title":"Gut susceptibility to viral invasion: contributing roles of diet, microbiota and enteric nervous system to mucosal barrier preservation","volume":"22","author":"Julio-Pieper","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.rvsc.2026.106299_bb0045","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s44149-021-00003-x","article-title":"Roles of bile acids in enteric virus replication","volume":"1","author":"Kong","year":"2021","journal-title":"Anim. Dis."},{"key":"10.1016\/j.rvsc.2026.106299_bb0050","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2209514119","article-title":"SARS-CoV-2 requires acidic pH to infect cells","volume":"119","author":"Kreutzberger","year":"2022","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.rvsc.2026.106299_bb0055","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0378-1135(90)90144-K","article-title":"Molecular biology of transmissible gastroenteritis virus","volume":"23","author":"Laude","year":"1990","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.rvsc.2026.106299_bb0060","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1016\/S0140-6736(88)92236-2","article-title":"Effect of bile salts and of fusidic acid on HIV-1 infection of cultured cells","volume":"331","author":"Lloyd","year":"1988","journal-title":"Lancet"},{"key":"10.1016\/j.rvsc.2026.106299_bb0065","doi-asserted-by":"crossref","first-page":"5140","DOI":"10.1016\/j.csbj.2021.08.049","article-title":"Predicted pH-dependent stability of SARS-CoV-2 spike protein trimer from interfacial acidic groups","volume":"19","author":"Lobo","year":"2021","journal-title":"Comput. Struct. Biotechnol. J."},{"key":"10.1016\/j.rvsc.2026.106299_bb0070","doi-asserted-by":"crossref","first-page":"6031","DOI":"10.3390\/ijms20236031","article-title":"The phylogeny and biological function of gastric juice\u2014microbiological consequences of removing gastric acid","volume":"20","author":"Martinsen","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.rvsc.2026.106299_bb0075","doi-asserted-by":"crossref","first-page":"102906","DOI":"10.1016\/j.jevs.2019.102906","article-title":"Equine coronavirus-associated colitis in horses: a retrospective study","volume":"87","author":"Mattei","year":"2020","journal-title":"J. Equine Vet. Sci."},{"key":"10.1016\/j.rvsc.2026.106299_bb0080","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1128\/JVI.02146-06","article-title":"The cytoplasmic tail of the severe acute respiratory syndrome coronavirus spike protein contains a novel endoplasmic reticulum retrieval signal that binds COPI and promotes interaction with membrane protein","volume":"81","author":"McBride","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.rvsc.2026.106299_bb0085","series-title":"Ref. Modul. Life Sci.","article-title":"Viruses associated with foodborne infections","author":"O\u2019Shea","year":"2019"},{"key":"10.1016\/j.rvsc.2026.106299_bb0090","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1007\/s12560-022-09518-z","article-title":"Occurrence of norovirus, rotavirus, hepatitis A virus, and enterovirus in berries in Argentina","volume":"14","author":"Oteiza","year":"2022","journal-title":"Food Environ. Virol."},{"key":"10.1016\/j.rvsc.2026.106299_bb0095","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.str.2023.02.006","article-title":"Molecular architecture and dynamics of SARS-CoV-2 envelope by integrative modeling","volume":"31","author":"Pezeshkian","year":"2023","journal-title":"Structure"},{"key":"10.1016\/j.rvsc.2026.106299_bb0100","first-page":"360","article-title":"Development of digestive functions in the newborn ruminant","volume":"14","author":"Ruckebusch","year":"1983","journal-title":"Ann. Rech. Veterinaires Ann. Vet. Res."},{"key":"10.1016\/j.rvsc.2026.106299_bb0105","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.ejpb.2016.09.009","article-title":"Resolving the physiological conditions in bioavailability and bioequivalence studies: comparison of fasted and fed state","volume":"108","author":"Schneider","year":"2016","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.rvsc.2026.106299_bb0110","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.02284-20","article-title":"Insight into vaccine development for Alphacoronaviruses based on structural and immunological analyses of spike proteins","volume":"95","author":"Shi","year":"2021","journal-title":"J. Virol."},{"key":"10.1016\/j.rvsc.2026.106299_bb0115","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1292\/jvms.66.717","article-title":"Sequence comparison of the ORF 7 region of transmissible gastroenteritis viruses isolated in Japan","volume":"66","author":"Taniguchi","year":"2004","journal-title":"J. Vet. Med. Sci."},{"key":"10.1016\/j.rvsc.2026.106299_bb0120","doi-asserted-by":"crossref","first-page":"656","DOI":"10.12935\/jvma1951.51.656","article-title":"Serological survey of porcine epidemic diarrhea virus infection in Tochigi prefecture","volume":"51","author":"Usami","year":"2011","journal-title":"J. Jpn. Vet. Med. Assoc."},{"key":"10.1016\/j.rvsc.2026.106299_bb0125","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1002\/bdrb.20040","article-title":"Postnatal development of the gastrointestinal system: a species comparison","volume":"74","author":"Walthall","year":"2005","journal-title":"Birth Defects Res. Part B Develop. Reprod. Toxicol."},{"key":"10.1016\/j.rvsc.2026.106299_bb0130","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2022.834011","article-title":"The physical basis for pH sensitivity in biomolecular structure and function, with application to the spike protein of SARS-CoV-2","volume":"9","author":"Warwicker","year":"2022","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.rvsc.2026.106299_bb0135","doi-asserted-by":"crossref","first-page":"3995","DOI":"10.1128\/JVI.06540-11","volume":"86","author":"Woo","year":"2012","journal-title":"J. Virol."}],"container-title":["Research in Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528826002535?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034528826002535?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T14:00:12Z","timestamp":1788444012000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034528826002535"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":27,"alternative-id":["S0034528826002535"],"URL":"https:\/\/doi.org\/10.1016\/j.rvsc.2026.106299","relation":{},"ISSN":["0034-5288"],"issn-type":[{"value":"0034-5288","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Infectious stability of animal gastrointestinal coronaviruses in fasted-state simulated gastric fluid","name":"articletitle","label":"Article Title"},{"value":"Research in Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rvsc.2026.106299","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"106299"}}