{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T05:42:59Z","timestamp":1787982179074,"version":"build-2784847793"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"publisher","award":["409090\/2018-2"],"award-info":[{"award-number":["409090\/2018-2"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004586","name":"FAPERJ","doi-asserted-by":"publisher","award":["E-26\/202.912\/2017"],"award-info":[{"award-number":["E-26\/202.912\/2017"]}],"id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.saa.2019.117139","type":"journal-article","created":{"date-parts":[[2019,5,20]],"date-time":"2019-05-20T21:26:20Z","timestamp":1558387580000},"page":"117139","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Quantification of neomycin in rubella vaccine by off\/on metal ion mediated photoluminescence from functionalized graphene quantum dots"],"prefix":"10.1016","volume":"220","author":[{"given":"Igor Ara\u00fajo","family":"Pinto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos A.T.","family":"Toloza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseany M.S.","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea R.","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dunieskys G.","family":"Larrude","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo Q.","family":"Auc\u00e9lio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2019.117139_bb0005","doi-asserted-by":"crossref","first-page":"4015","DOI":"10.1039\/c3nr33849e","article-title":"Focusing on luminescent graphene quantum dots: current status and future perspectives","volume":"5","author":"Li","year":"2013","journal-title":"Nanoscale"},{"key":"10.1016\/j.saa.2019.117139_bb0010","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1039\/C0CC04812G","article-title":"Facile preparation and upconversion luminescence of graphene quantum dots","volume":"47","author":"Shen","year":"2011","journal-title":"Chem. Commun."},{"key":"10.1016\/j.saa.2019.117139_bb0015","doi-asserted-by":"crossref","first-page":"15221","DOI":"10.1021\/ja204953k","article-title":"Bottom-up fabrication o photoluminescent graphene quantum dots with uniform morphology","volume":"133","author":"Liu","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.saa.2019.117139_bb0020","doi-asserted-by":"crossref","first-page":"8211","DOI":"10.1002\/adfm.201603803","article-title":"Modulating the photocatalytic activity of graphene quantum dots via atomic tailoring for highly enhanced photocatalysis under visible light","volume":"26","author":"Jeon","year":"2016","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.saa.2019.117139_bb0025","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1002\/adma.200902871","article-title":"Aqueous-processable noncovalent chemically converted graphene quantum dot composites for flexible and transparent optoelectronic films","volume":"22","author":"Geng","year":"2010","journal-title":"Adv. Mater."},{"key":"10.1016\/j.saa.2019.117139_bb0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1088\/0957-4484\/24\/19\/195401","article-title":"Graphene quantum dots\u2013carbon nanotube hybrid arrays for supercapacitors","volume":"24","author":"Hu","year":"2013","journal-title":"Nanotechnology"},{"key":"10.1016\/j.saa.2019.117139_bb0035","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1021\/am302938a","article-title":"Nearly monodisperse graphene quantum dots fabricated by amine-assisted cutting and ultrafiltration","volume":"5","author":"Chen","year":"2013","journal-title":"ACS APPI. Mater. Interfaces"},{"key":"10.1016\/j.saa.2019.117139_bb0040","doi-asserted-by":"crossref","first-page":"3760","DOI":"10.1021\/ja4132246","article-title":"Efficiency enhancement of perovskite solar cells through fast electron extraction: the role of graphene quantum dots","volume":"136","author":"Zhu","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.saa.2019.117139_bb0045","doi-asserted-by":"crossref","unstructured":"L. L. Li, G. H. Wu, T. Hong, Z. Y. Yin, D. Sun, E. S. Abdel-Halim, J. J. Zhu, Graphene quantum dots as fluorescence probes for turn-off sensing of melamine in the presence of hg2+, ACS APPI. Mater. Interfaces 6 (2013) 2858\u20132864. doi:https:\/\/doi.org\/10.1021\/am405305r.","DOI":"10.1021\/am405305r"},{"key":"10.1016\/j.saa.2019.117139_bb0050","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.snb.2013.09.009","article-title":"Graphene quantum dots as a fluorescent sensing platform for highly efficient detection of copper (II) ions","volume":"190","author":"Wang","year":"2014","journal-title":"Sensors Actuators B Chem."},{"key":"10.1016\/j.saa.2019.117139_bb0055","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.bios.2014.02.061","article-title":"Synthesis of highly fluorescent nitrogen-doped graphene quantum dots for sensitive, label-free detection of Fe (III) in aqueous media","volume":"58","author":"Ju","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.saa.2019.117139_bb0060","doi-asserted-by":"crossref","first-page":"8246","DOI":"10.1021\/am4023863","article-title":"Surface coating of graphene quantum dots using mussel-inspired polydopamine for biomedical optical imaging","volume":"5","author":"Nurunnabi","year":"2013","journal-title":"ACS APPI. Mater. Interfaces"},{"key":"10.1016\/j.saa.2019.117139_bb0065","doi-asserted-by":"crossref","first-page":"2436","DOI":"10.1021\/nl400368v","article-title":"Strong two-photon-induced fluorescence from photostable, biocompatible nitrogen-doped graphene quantum dots for cellular and deep-tissue imaging","volume":"13","author":"Liu","year":"2013","journal-title":"Nano Lett."},{"key":"10.1016\/j.saa.2019.117139_bb0070","first-page":"1810\u22121815","article-title":"Glutathione-functionalized graphene quantum dots as selective fluorescent probes for phosphate-containing metabolites","volume":"5","author":"Liu","year":"2013","journal-title":"Nanoscale"},{"key":"10.1016\/j.saa.2019.117139_bb0075","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1039\/C1NJ20658C","article-title":"One-pot hydrothermal synthesis of graphene quantum dots surface-passivated by polyethylene glycol and their photoelectric conversion under near-infrared light","volume":"36","author":"Shen","year":"2012","journal-title":"New J. Chem."},{"key":"10.1016\/j.saa.2019.117139_bb0080","doi-asserted-by":"crossref","first-page":"6156","DOI":"10.1021\/cr3000412","article-title":"Functionalization of graphene: covalent and non-covalent approaches, derivatives and applications","volume":"112","author":"Georgakilas","year":"2012","journal-title":"Chem. Rev."},{"key":"10.1016\/j.saa.2019.117139_bb0085","doi-asserted-by":"crossref","unstructured":"M. Kanemoto, H. Sekiguchi, K. Yamane, H. Okada, A.Wakahara, Eu3+ luminescence properties of Eu- and Mg-codoped AlGaN, J. Lumin. 166 (2015) 60\u201366. doi:https:\/\/doi.org\/10.1016\/j.jlumin.2015.04.036.","DOI":"10.1016\/j.jlumin.2015.04.036"},{"key":"10.1016\/j.saa.2019.117139_bb0090","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.jlumin.2014.09.036","article-title":"Enhanced excitation efficiency of Eu ions in Eu-doped GaN\/AlGaN multiple quantum well structures grown by organometallic vapor phase epitaxy","volume":"158","author":"Arai","year":"2015","journal-title":"J. Lumin."},{"key":"10.1016\/j.saa.2019.117139_bb0095","doi-asserted-by":"crossref","first-page":"3822","DOI":"10.1002\/chem.201204295","article-title":"Graphene quantum dots combined with europium ions as photoluminescent probes for phosphate sensing","volume":"19","author":"Bai","year":"2013","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.saa.2019.117139_bb0100","doi-asserted-by":"crossref","unstructured":"L. Lin, X. Song, Y. Chen, M. Rong, Y. Wang, L. Zhao, T. Zhao, X. Chen, Europium-decorated graphene quantum dots as a fluorescent probe for label-free, rapid and sensitive detection of Cu2+ and L-cysteine, Anal. Chim. Acta 891 (2015) 261\u2013268. doi:https:\/\/doi.org\/10.1016\/j.aca.2015.08.011.","DOI":"10.1016\/j.aca.2015.08.011"},{"key":"10.1016\/j.saa.2019.117139_bb0105","doi-asserted-by":"crossref","unstructured":"C. A. T. Toloza, S. Khan, R. L. D. Silva, E. C. Romani, D. G. Larrude, S. R. W. Louro, F. L. Freire J\u00fanior, R. Q. Auc\u00e9lio, Photoluminescence suppression effect caused by histamine on amino-functionalized graphene quantum dots with the mediation of Fe3+, Cu2+, Eu3+: application in the analysis of spoiled tuna fish, Microchem. J. 133 (2017) 448\u2013459. doi:https:\/\/doi.org\/10.1016\/j.microc.2017.04.013.","DOI":"10.1016\/j.microc.2017.04.013"},{"key":"10.1016\/j.saa.2019.117139_bb0110","doi-asserted-by":"crossref","first-page":"6593","DOI":"10.1039\/C7TB00506G","article-title":"S co-doped graphene quantum dots and their application for parallel detection of multiple metal ions","volume":"5","author":"Shen","year":"2017","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.saa.2019.117139_bb0115","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.saa.2018.07.097","article-title":"Nitrogen and sulfur co-doped graphene quantum dots for the highly sensitive and selective detection of mercury ion in living cells","volume":"206","author":"Qu","year":"2019","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2019.117139_bb0120","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1126\/science.109.2830.305","article-title":"Neomycin, a new antibiotic active against streptomycin-resistant bacteria, including tuberculosis organisms","volume":"109","author":"Waksman","year":"1949","journal-title":"Science"},{"key":"10.1016\/j.saa.2019.117139_bb0125","first-page":"594","article-title":"Toxicity of aminoglycoside antibiotics","volume":"58","author":"Clark","year":"1977","journal-title":"Mod. Vet. Pract."},{"key":"10.1016\/j.saa.2019.117139_bb0130","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1007\/s00604-015-1480-1","article-title":"Colorimetric determination of neomycin using melamine modified gold nanoparticles","volume":"182","author":"Xiao","year":"2015","journal-title":"Microchim. Acta"},{"key":"10.1016\/j.saa.2019.117139_bb0135","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1080\/09540105.2011.569882","article-title":"Development and application of one-step ELISA for the detection of neomycin in milk","volume":"22","author":"Xu","year":"2011","journal-title":"Food Agric. Immunol."},{"key":"10.1016\/j.saa.2019.117139_bb0140","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1016\/j.bios.2009.01.011","article-title":"SPR sensing of small molecules with modified RNA aptamers: detection of neomycin B","volume":"24","author":"De-Los-Santos-Alvarez","year":"2009","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.saa.2019.117139_bb0145","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1002\/marc.201200837","article-title":"Colorimetric and fluorometric detection of neomycin based on conjugated polydiacetylene supramolecules","volume":"34","author":"Zhou","year":"2013","journal-title":"Macromol. Rapid Commun."},{"key":"10.1016\/j.saa.2019.117139_bb0150","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.saa.2014.07.020","article-title":"Validated spectrofluorimetric method for determination of selected aminoglycosides","volume":"135","author":"Omar","year":"2015","journal-title":"Spectrochim. Acta A"},{"key":"10.1016\/j.saa.2019.117139_bb0155","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1080\/00032719.2016.1261876","article-title":"Electrochemical determination of neomycin and norfloxacin at a novel polymer nanocomposite electrode in aqueous solution","volume":"50","author":"Hamnca","year":"2017","journal-title":"Anal. Lett."},{"key":"10.1016\/j.saa.2019.117139_bb0160","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0021-9673(04)01570-5","article-title":"Hydrophilic interaction chromatography combined with tandem-mass spectrometry to determine six aminoglycosides in serum","volume":"1058","author":"Oertel","year":"2004","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.saa.2019.117139_bb0165","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jchromb.2006.01.034","article-title":"Analysis of neomycin using an improved liquid chromatographic method combined with pulsed electrochemical detection","volume":"833","author":"Zawilla","year":"2006","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.saa.2019.117139_bb0170","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.cclet.2006.12.022","article-title":"Determination of neomycin in water samples by high performance anion chromatography with pulsed amperometric detection","volume":"18","author":"Guan","year":"2007","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.saa.2019.117139_bb0175","doi-asserted-by":"crossref","first-page":"2496","DOI":"10.1080\/00032711003725599","article-title":"Sample preparation for determination of neomycin in swine tissues by liquid chromatography-fluorescence detection","volume":"43","author":"Chen","year":"2010","journal-title":"Anal. Lett."},{"key":"10.1016\/j.saa.2019.117139_bb0180","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.snb.2017.02.117","article-title":"Thioglycolic acid-CdTe quantum dots sensing and molecularly imprinted polymer based solid phase extraction for the determination of kanamycin in milk, vaccine and stream water samples","volume":"246","author":"Khan","year":"2017","journal-title":"Sensors Actuators B Chem."},{"key":"10.1016\/j.saa.2019.117139_bb0185","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jpba.2018.02.028","article-title":"Rapid determination of neomycin in biological samples using fluorescent sensor based on quantum dots with doubly selective binding sites","volume":"154","author":"Wan","year":"2018","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.saa.2019.117139_bb0190","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1002\/smll.201301770","article-title":"Size-controlled soft-template synthesis of carbon nanodots toward versatile photoactive materials","volume":"10","author":"Kwon","year":"2014","journal-title":"Small"},{"key":"10.1016\/j.saa.2019.117139_bb0195","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.jpba.2018.05.050","article-title":"Gold nanoparticles coupled with graphene quantum dots in organized medium to quantify aminoglycoside anti-biotics in yellow fever vaccine after solid phase extraction using a selective imprinted polymer","volume":"158","author":"Toloza","year":"2018","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.saa.2019.117139_bb0200","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.microc.2018.10.041","article-title":"Determination of gentamicin sulfate by batch-injection amperometry after solid-phase extraction using a kanamycin-template imprinted polymer","volume":"145","author":"Almeida","year":"2019","journal-title":"Microchem. J."}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142519305293?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142519305293?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T01:08:28Z","timestamp":1761354508000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386142519305293"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":40,"alternative-id":["S1386142519305293"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2019.117139","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quantification of neomycin in rubella vaccine by off\/on metal ion mediated photoluminescence from functionalized graphene quantum dots","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2019.117139","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"117139"}}