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Ranjbar, Y. Shokoohinia, S. Ghobadi, N. Bijari, S. Gholamzadeh, N. Moradi, M.R. Ashrafi-Kooshk, A. Aghaei, R. Khodarahmi, Studies of the interaction between isoimperatorin and human serum albumin by multispectroscopic method: identification of possible binding site of the compound using esterase activity of the protein, ScientificWorldJournal 2013 (2013) 305081.","DOI":"10.1155\/2013\/305081"},{"key":"10.1016\/j.saa.2019.117330_bb0400","doi-asserted-by":"crossref","first-page":"2876","DOI":"10.1038\/nprot.2006.202","article-title":"Using circular dichroism spectra to estimate protein secondary structure","volume":"1","author":"Greenfield","year":"2006","journal-title":"Nat. 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