{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T05:49:49Z","timestamp":1781761789560,"version":"3.54.5"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007128","name":"Natural Science Foundation of Shaanxi Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007128","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.saa.2019.117341","type":"journal-article","created":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T11:34:53Z","timestamp":1562585693000},"page":"117341","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Fabrication of paper-based microfluidic device by recycling foamed plastic and the application for multiplexed measurement of biomarkers"],"prefix":"10.1016","volume":"223","author":[{"given":"Xiaoyan","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiru","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2019.117341_bb0005","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1002\/anie.200603817","article-title":"Patterned paper as a platform for inexpensive, low-volume, portable bioassays","volume":"46","author":"Martinez","year":"2007","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.saa.2019.117341_bb0010","doi-asserted-by":"crossref","first-page":"8447","DOI":"10.1021\/acs.chemrev.7b00024","article-title":"Turning the page: advancing paper-based microfluidics for broad diagnostic application","volume":"117","author":"Gong","year":"2017","journal-title":"Chem. Rev."},{"key":"10.1016\/j.saa.2019.117341_bb0015","doi-asserted-by":"crossref","first-page":"23884","DOI":"10.1021\/acsami.7b08826","article-title":"Self-diffusion driven ultrafast detection of ppm-level nitroaromatic pollutants in aqueous media using a hydrophilic fluorescent paper sensor","volume":"9","author":"Lu","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.saa.2019.117341_bb0020","doi-asserted-by":"crossref","first-page":"11343","DOI":"10.1021\/acsami.8b01133","article-title":"Inkjet printing enabled controllable paper superhydrophobization and its applications","volume":"10","author":"Zhang","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.saa.2019.117341_bb0025","doi-asserted-by":"crossref","first-page":"3699","DOI":"10.1021\/ac800112r","article-title":"Simple telemedicine for developing regions: camera phones and paper-based microfluidic devices for real-time, off-site diagnosis","volume":"80","author":"Martinez","year":"2008","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0030","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.trac.2017.06.005","article-title":"Paper-based microfluidic analytical devices for colorimetric detection of toxic ions: a review","volume":"93","author":"Sriram","year":"2017","journal-title":"TrAC Trends Anal. Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0035","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1039\/b811135a","article-title":"FLASH: a rapid method for prototyping paper-based microfluidic devices","volume":"8","author":"Martinez","year":"2008","journal-title":"Lab Chip"},{"key":"10.1016\/j.saa.2019.117341_bb0040","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1021\/ac9013989","article-title":"Diagnostics for the developing world: microfluidic paper-based analytical devices","volume":"82","author":"Martinez","year":"2010","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0045","doi-asserted-by":"crossref","first-page":"6928","DOI":"10.1021\/ac800604v","article-title":"Inkjet-printed microfluidic multianalyte chemical sensing paper","volume":"80","author":"Abe","year":"2008","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0050","doi-asserted-by":"crossref","first-page":"6331","DOI":"10.1021\/ac203496c","article-title":"Low-cost fabrication of paper-based microfluidic devices by one-step plotting","volume":"84","author":"Nie","year":"2012","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0055","doi-asserted-by":"crossref","first-page":"1601660","DOI":"10.1126\/sciadv.1601660","article-title":"Ultrathin high-resolution flexographic printing using nanoporous stamps","volume":"2","author":"Kim","year":"2016","journal-title":"Sci. Adv."},{"key":"10.1016\/j.saa.2019.117341_bb0060","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.talanta.2016.06.040","article-title":"Rapid and alternative fabrication method for microfluidic paper based analytical devices","volume":"159","author":"Malekghasemi","year":"2016","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2019.117341_bb0065","doi-asserted-by":"crossref","first-page":"7896","DOI":"10.1038\/s41598-019-44455-1","article-title":"Fabrication of laser printed microfuidic paper-based analytical devices (LP-\u03bcPADs) for point-of care applications","volume":"9","author":"Ghosh","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.saa.2019.117341_bb0070","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.saa.2014.09.059","article-title":"A paper-based chemiluminescence device for the determination of ofloxacin","volume":"137","author":"Liu","year":"2015","journal-title":"Spectrochim. Acta A"},{"key":"10.1016\/j.saa.2019.117341_bb0075","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1002\/elps.200800563","article-title":"Rapid prototyping of paper-based microfluidics with wax for low-cost, portable bioassay","volume":"30","author":"Lu","year":"2009","journal-title":"Electrophoresis"},{"key":"10.1016\/j.saa.2019.117341_bb0080","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.snb.2017.04.126","article-title":"Paper-based chemiluminescence immunodevice with temporal controls of reagent transport technique","volume":"250","author":"Chu","year":"2017","journal-title":"Sens. Actuators B: Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0085","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.snb.2018.12.004","article-title":"Rapid fabrication of microfluidic paper-based analytical devices by microembossing","volume":"283","author":"Juang","year":"2019","journal-title":"Sens. Actuators B: Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0090","doi-asserted-by":"crossref","first-page":"4605","DOI":"10.1021\/la204492q","article-title":"Simple method for preparing superhydrophobic paper: spray-deposited hydrophobic silica nanoparticle coatings exhibit high water-repellency and transparency","volume":"28","author":"Ogihara","year":"2012","journal-title":"Langmuir"},{"key":"10.1016\/j.saa.2019.117341_bb0095","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1021\/ac503968p","article-title":"Recent developments in paper-based microfluidic devices","volume":"87","author":"Cate","year":"2015","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0100","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.1016\/j.talanta.2011.08.024","article-title":"Novel, simple and low-cost alternative method for fabrication of paper-based microfluidics by wax dipping","volume":"85","author":"Songjaroen","year":"2011","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2019.117341_bb0105","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1039\/C5LC00044K","article-title":"Microfluidic paper-based analytical devices fabricated by low-cost photolithography and embossing of Parafilm\u00ae","volume":"15","author":"Yu","year":"2015","journal-title":"Lab Chip"},{"key":"10.1016\/j.saa.2019.117341_bb0110","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.aca.2018.12.001","article-title":"Low-cost fabrication of a paper-based microfluidic using a folded pattern paper","volume":"1053","author":"Xie","year":"2019","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.saa.2019.117341_bb0115","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.ab.2017.03.001","article-title":"Development of a paper-based microfluidic analytical device by a more facile hydrophobic substrate generation strategy","volume":"525","author":"Xue","year":"2017","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.saa.2019.117341_bb0120","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1038\/s41598-018-38308-6","article-title":"Fabricating paper based devices using correction pens","volume":"9","author":"Mani","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.saa.2019.117341_bb0125","doi-asserted-by":"crossref","first-page":"37637","DOI":"10.1039\/C4RA07112C","article-title":"A handheld stamping process to fabricate microfluidic paper-based analytical devices with chemically modified surface for clinical assays","volume":"4","author":"Garcia","year":"2014","journal-title":"RSC Adv."},{"key":"10.1016\/j.saa.2019.117341_bb0130","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.snb.2014.05.087","article-title":"Paper-based electrochemiluminescence immunodevice for carcinoembryonic antigen using nanoporous gold-chitosan hybrids and graphene quantum dots functionalized au@Pt","volume":"202","author":"Li","year":"2014","journal-title":"Sens. Actuators B: Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0135","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.bios.2011.10.019","article-title":"Paper-based chemiluminescence ELISA: lab-on-paper based on chitosan modified paper device and wax-screen-printing","volume":"31","author":"Wang","year":"2012","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.saa.2019.117341_bb0140","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1007\/s10570-010-9401-2","article-title":"Progress in patterned paper sizing for fabrication of paper-based microfluidic sensors","volume":"17","author":"Li","year":"2010","journal-title":"Cellulose"},{"key":"10.1016\/j.saa.2019.117341_bb0145","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1021\/ac303138x","article-title":"Method for fabrication of paper-based microfluidic devices by alkylsilane self-assembling and UV\/O3-patterning","volume":"85","author":"He","year":"2013","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0150","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1039\/C3LC51313K","article-title":"Hydrophobic sol\u2013gel channel patterning strategies for paper-based microfluidics","volume":"14","author":"Wang","year":"2014","journal-title":"Lab Chip"},{"key":"10.1016\/j.saa.2019.117341_bb0155","doi-asserted-by":"crossref","first-page":"4593","DOI":"10.1039\/C4AN00988F","article-title":"Fabrication of a microfluidic paper-based analytical device by silanization of filter cellulose using a paper mask for glucose assay","volume":"139","author":"Cai","year":"2014","journal-title":"Analyst"},{"key":"10.1016\/j.saa.2019.117341_bb0160","doi-asserted-by":"crossref","first-page":"42366","DOI":"10.1021\/acsami.7b14122","article-title":"Low-cost chemical-responsive adhesive sensing chips","volume":"9","author":"Tan","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.saa.2019.117341_bb0165","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1039\/C0AN00406E","article-title":"A low-cost, simple, and rapid fabrication method for paper-based microfluidics using wax screen-printing","volume":"136","author":"Dungchai","year":"2011","journal-title":"Analyst"},{"key":"10.1016\/j.saa.2019.117341_bb0175","doi-asserted-by":"crossref","first-page":"104001","DOI":"10.1088\/1361-6439\/aa82ce","article-title":"Direct spraying method for fabrication of paper-based microfluidic devices","volume":"27","author":"Liu","year":"2017","journal-title":"J. Micromech. Microeng."},{"key":"10.1016\/j.saa.2019.117341_bb0180","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.bios.2018.02.012","article-title":"Electrochemical integrated paper-based immunosensor modified with multiwalled carbon nanotubes nanocomposites for point-of-care testing of 17 \u03b2-estradiol","volume":"107","author":"Wang","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.saa.2019.117341_bb0185","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.snb.2017.12.197","article-title":"Distance-based carcinoembryonic antigen assay on microfluidic paper immunodevice","volume":"260","author":"Chen","year":"2018","journal-title":"Sens. Actuators B: Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0190","doi-asserted-by":"crossref","first-page":"8661","DOI":"10.1021\/ac401445a","article-title":"Paper-based microfluidic electrochemical immunodevice integrated with nanobioprobes onto graphene film for ultrasensitive multiplexed detection of cancer biomarkers","volume":"85","author":"Wu","year":"2013","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0195","doi-asserted-by":"crossref","first-page":"7951","DOI":"10.1021\/acs.analchem.5b01814","article-title":"Ring-oven washing technique integrated paper-based immunodevice for sensitive detection of cancer biomarker","volume":"87","author":"Liu","year":"2015","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0200","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.bios.2015.12.099","article-title":"Plasma treatment of paper for protein immobilization on paper-based chemiluminescence immunodevice","volume":"79","author":"Zhao","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.saa.2019.117341_bb0205","doi-asserted-by":"crossref","first-page":"10270","DOI":"10.1021\/ac402055n","article-title":"Laminated paper-based analytical devices (LPAD) with origami-enabled chemiluminescence immunoassay for cotinine detection in mouse serum","volume":"85","author":"Liu","year":"2013","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2019.117341_bb0210","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1021\/bp00020a003","article-title":"Catalytic peptide synthesis by trypsin modified with polystyrene in chloroform","volume":"9","author":"Ito","year":"1993","journal-title":"Biotechnol. Prog."},{"key":"10.1016\/j.saa.2019.117341_bb0215","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.snb.2014.11.088","article-title":"Chemiluminescence excited photoelectrochemical competitive immunosensing lab-on-paper device using an integrated paper supercapacitor for signal amplication","volume":"208","author":"Wang","year":"2015","journal-title":"Sens. Actuators B: Chem."}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142519307310?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142519307310?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T01:10:51Z","timestamp":1761354651000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386142519307310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":42,"alternative-id":["S1386142519307310"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2019.117341","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fabrication of paper-based microfluidic device by recycling foamed plastic and the application for multiplexed measurement of biomarkers","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2019.117341","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"117341"}}