{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T12:33:21Z","timestamp":1761395601068,"version":"build-2065373602"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100011089","name":"PLGrid infrastructure","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011089","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.saa.2019.117757","type":"journal-article","created":{"date-parts":[[2019,11,5]],"date-time":"2019-11-05T12:30:03Z","timestamp":1572957003000},"page":"117757","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["2\u2032-(1H-phenanthro[9,10-d]imidazol-2-yl)-phenyl-4-carboxylic acid N-hydroxysuccinimide ester: A new phenanthroimidazole derivative as a fluorescent probe for medical imaging applications"],"prefix":"10.1016","volume":"228","author":[{"given":"Przemys\u0142aw","family":"Krawczyk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Wybranowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0141ukasz","family":"Ka\u017amierski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iga","family":"Ho\u0142y\u0144ska-Iwan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdalena","family":"Bratkowska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Cysewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beata","family":"J\u0119drzejewska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2019.117757_bb0005","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s00259-005-1973-y","article-title":"Primer on molecular imaging technology","volume":"32","author":"Levin","year":"2005","journal-title":"Eur. J. Nucl. Med. Mol. I."},{"issue":"2","key":"10.1016\/j.saa.2019.117757_bb0010","first-page":"335","volume":"34","author":"Bil","year":"2007","journal-title":"Post\u0119py biologii kom\u00f3rki"},{"key":"10.1016\/j.saa.2019.117757_bb0015","first-page":"365","article-title":"Targets and strategies for imaging dynamics of molecular-cell interactions in autoimmune disorders","volume":"6","author":"So\u0142tysi\u0144ski","year":"2007","journal-title":"Mol. Imaging"},{"key":"10.1016\/j.saa.2019.117757_bb0020","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1002\/jemt.20912","article-title":"Bimodal magnetic-fluorescent probes for bioimaging","volume":"74","author":"Janczewski","year":"2011","journal-title":"Microsc. Res. Tech."},{"issue":"18","key":"10.1016\/j.saa.2019.117757_bb0025","doi-asserted-by":"crossref","first-page":"3030","DOI":"10.1039\/c3ob27445d","article-title":"FRET-based imaging of transbilayer movement of pepducin in living cells by novel intracellular bioreductively activatable fluorescent probes","volume":"11","author":"Tsuji","year":"2013","journal-title":"Org. Biomol. Chem."},{"issue":"1","key":"10.1016\/j.saa.2019.117757_bb0030","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1021\/cr020357g","article-title":"Upconversion and anti-stokes processes with f and d ions in solids","volume":"104","author":"Auzel","year":"2004","journal-title":"Chem. Rev."},{"key":"10.1016\/j.saa.2019.117757_bb0035","doi-asserted-by":"crossref","first-page":"3788","DOI":"10.1039\/C8OB00729B","article-title":"Reactive group effects on the photophysical and biological properties of 2-phenyl-1H-phenanthro[9,10-d]imidazole derivatives as fluorescent markers","volume":"16","author":"Krawczyk","year":"2018","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.saa.2019.117757_bb0040","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1002\/bio.2580","article-title":"Study on the synthesis and structure effect relationship of multi-aryl imidazoles with their fluorescence properties","volume":"29","author":"Tian","year":"2014","journal-title":"Luminescence"},{"key":"10.1016\/j.saa.2019.117757_bb0045","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1042\/bj0510155","article-title":"Polarization of the fluorescence of macromolecules. 2. Fluorescent conjugates of ovalbumin and bovine serum albumin","volume":"51","author":"Weber","year":"1952","journal-title":"Biochem. J."},{"key":"10.1016\/j.saa.2019.117757_bb0050","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1042\/bj0510145","article-title":"Polarization of the fluorescence of macromolecules. 1. Theory and experimental method","volume":"51","author":"Weber","year":"1952","journal-title":"Biochem. J."},{"year":"1999","series-title":"Principles of Fluorescence Spectroscopy","author":"Lakowic","key":"10.1016\/j.saa.2019.117757_bb0055"},{"key":"10.1016\/j.saa.2019.117757_bb0060","doi-asserted-by":"crossref","first-page":"2685","DOI":"10.1021\/cr900267p","volume":"110","author":"Jameson","year":"2010","journal-title":"Chem. Rev."},{"key":"10.1016\/j.saa.2019.117757_bb0065","doi-asserted-by":"crossref","first-page":"647","DOI":"10.4149\/gpb_2018017","article-title":"The impact of oxidative stress on binding of drugs with plasma proteins studied by fluorescence anisotropy methods","volume":"37","author":"Wybranowski","year":"2018","journal-title":"Gen. Physiol. Biophys."},{"key":"10.1016\/j.saa.2019.117757_bb0070","doi-asserted-by":"crossref","first-page":"87","DOI":"10.2142\/biophysico.13.0_87","article-title":"Mass spectrometric analysis of protein\u2013ligand interactions","volume":"13","author":"Ishii","year":"2016","journal-title":"Biophys Physicobiol."},{"key":"10.1016\/j.saa.2019.117757_bb0075","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/nprot.2007.73","article-title":"Determining the stoichiometry and interactions of macromolecular assemblies from mass spectrometry","volume":"2","author":"Hernandez","year":"2007","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.saa.2019.117757_bb0080","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1586\/epr.10.109","article-title":"Differential hydrogen\/deuterium exchange mass spectrometry analysis of protein\u2013ligand interactions","volume":"8","author":"Chalmers","year":"2011","journal-title":"Expert Rev Proteomics"},{"key":"10.1016\/j.saa.2019.117757_bb0085","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/978-1-59745-398-1_15","article-title":"Mass spectrometry to study noncovalent protein\/protein and protein\/ligand complexes: technical aspects and application to the determination of binding stoichiometries","volume":"484","author":"Sanglier","year":"2008","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.saa.2019.117757_bb0090","doi-asserted-by":"crossref","first-page":"4629","DOI":"10.1016\/j.bmcl.2011.05.090","article-title":"Synthesis of d-labeled and unlabeled benzoyloxysuccinimides and application to quantitative analysis of peptides and a protein by isotope differential mass spectrometry","volume":"21","author":"Zabet-Moghaddam","year":"2011","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.saa.2019.117757_bb0095","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1351\/PAC-REP-10-09-31","article-title":"Standards for photoluminescence quantum yield measurements in solution (IUPAC Technical Report)","volume":"83","author":"Brouwer A.","year":"2011","journal-title":"Pure Appl. Chem."},{"key":"10.1016\/j.saa.2019.117757_bb0100","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1021\/j100483a006","article-title":"Calorimetric determinations of absolute fluorescence quantum yields","volume":"83","author":"Olmsted","year":"1979","journal-title":"J. Phys. Chem."},{"key":"10.1016\/j.saa.2019.117757_bb0105","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1111\/exd.12750","article-title":"Modulation of transepithelial electric resistance (TEER) in reconstructed human epidermis by excipients known to permeate intestinal tight junctions","volume":"24","author":"Abdayem","year":"2015","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.saa.2019.117757_bb0110","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.pestbp.2018.04.011","article-title":"The immediate influence of deltamethrin on ion transport through rabbit skin. An in vitro study","volume":"148","author":"Ho\u0142y\u0144ska-Iwan","year":"2018","journal-title":"Pest. Biochem. Physiol."},{"key":"10.1016\/j.saa.2019.117757_bb0115","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.biosystems.2008.05.034","article-title":"The HSA affinity of warfarin and flurbiprofen determined by fluorescence anisotropy measurements of camptothecin","volume":"94","author":"Wybranowski","year":"2008","journal-title":"Biosystems"},{"year":"2009","series-title":"Gaussian 09, Revision A.1","author":"Frisch","key":"10.1016\/j.saa.2019.117757_bb0120"},{"key":"10.1016\/j.saa.2019.117757_bb0125","doi-asserted-by":"crossref","first-page":"2889","DOI":"10.1063\/1.479571","article-title":"Accurate excitation energies from time-dependent density functional theory: assessing the PBE0 model","volume":"111","author":"Adamo","year":"1999","journal-title":"J. Chem. Phys."},{"author":"Guido","key":"10.1016\/j.saa.2019.117757_bb0130"},{"key":"10.1016\/j.saa.2019.117757_bb0135","doi-asserted-by":"crossref","first-page":"3032","DOI":"10.1063\/1.474659","article-title":"A new integral equation formalism for the polarizable continuum model: theoretical background and applications to isotropic and anisotropic dielectrics","volume":"107","author":"Canc\u00e9s","year":"1997","journal-title":"J. Chem. Phys."},{"key":"10.1016\/j.saa.2019.117757_bb0140","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.saa.2012.11.033","article-title":"PCM\/TD-DFT analysis of 1-bromo-2,3-dichlorobenzene \u2013 a combined study of experimental (FT-IR and FT-Raman) and theoretical calculations","volume":"105","author":"Arivazhagan","year":"2013","journal-title":"Spectrochim. Acta Part A"},{"key":"10.1016\/j.saa.2019.117757_bb0145","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1002\/jcc.21256","article-title":"AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility","volume":"30","author":"Morris","year":"2009","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.saa.2019.117757_bb0150","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1517\/17460441.2010.484460","article-title":"Virtual screening with AutoDock: theory and practice","volume":"5","author":"Cosconati","year":"2010","journal-title":"Expert Opin. Drug Discovery"},{"key":"10.1016\/j.saa.2019.117757_bb0155","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1021\/jm2005145","article-title":"A force field with discrete displaceable waters and desolvation entropy for hydrated ligand docking","volume":"55","author":"Forli","year":"2012","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.saa.2019.117757_bb0160","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/jcc.21334","article-title":"AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading","volume":"31","author":"Trott","year":"2010","journal-title":"J. Comp. Chem."},{"key":"10.1016\/j.saa.2019.117757_bb0165","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1107\/S0907444905021475","article-title":"On the routine use of soft X-rays in macromolecular crystallography, part III- the optimal data collection wavelength","volume":"61","author":"Panjikar","year":"2005","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.saa.2019.117757_bb0170","series-title":"Protein Data Bank","article-title":"Crystal structure of human serum albumin","author":"Sugio","year":"1998"},{"issue":"6\u20137","key":"10.1016\/j.saa.2019.117757_bb0175","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/s10822-008-9203-x","article-title":"A new paradigm for pattern recognition of drugs","volume":"22","author":"Potemkin","year":"2008","journal-title":"J. Comput. Aided Mol. Des."},{"issue":"6","key":"10.1016\/j.saa.2019.117757_bb0180","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1021\/ci800405n","article-title":"Technique for energy decomposition in the study of \u201creceptor-ligand\u201d complexes","volume":"49","author":"Potemkin","year":"2009","journal-title":"J. Chem. Inf. Model."},{"key":"10.1016\/j.saa.2019.117757_bb0185","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jphotobiol.2016.07.044","article-title":"Synthesis, spectroscopic, physicochemical properties and binding site analysis of 4-(1H-phenanthro[9,10-d]-imidazol 2 yl) benzaldehyde fluorescent probe for imaging in cell biology: experimental and theoretical study","volume":"164","author":"Krawczyk","year":"2016","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.saa.2019.117757_bb0190","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jphotobiol.2016.11.008","article-title":"Synthesis, photophysical properties and systematic evaluations of new phenanthroimidazole fluorescent probe for bioimaging: experimental and theoretical study","volume":"166","author":"Krawczyk","year":"2017","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.saa.2019.117757_bb0195","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.dyepig.2014.01.025","article-title":"Synthesis and evaluation of spectroscopic properties of newly synthesized push\u2013pull 6-amino-8-styryl purines","volume":"105","author":"Vabre","year":"2014","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.saa.2019.117757_bb0200","doi-asserted-by":"crossref","first-page":"4542","DOI":"10.1021\/jp9115589","article-title":"Aromatic fumaronitrile core-based donor\u2212linker\u2212acceptor\u2212linker\u2212donor (D-\u03c0-A-\u03c0-D) compounds: synthesis and photophysical properties","volume":"114","author":"Panthi","year":"2010","journal-title":"J. Phys. Chem. A"},{"key":"10.1016\/j.saa.2019.117757_bb0205","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1021\/bc00013a001","article-title":"A brief survey of methods for preparing protein conjugates with dyes, haptens and crosslinking reagents","volume":"3","author":"Brinkley","year":"1992","journal-title":"Bioconjug. Chem."},{"issue":"2","key":"10.1016\/j.saa.2019.117757_bb0210","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1039\/b612870j","article-title":"Effect of the labelling ratio on the photophysics of fluorescein isothiocyanate (FITC) conjugated to bovine serum albumin","volume":"6","author":"Hungerford","year":"2007","journal-title":"Photochem. Photobiol. Sci."},{"key":"10.1016\/j.saa.2019.117757_bb0215","doi-asserted-by":"crossref","unstructured":"Ch. Lipinski, F. Lombardo,B.W Dominy, P.J. Feeney, Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1, Adv. Drug Deliv. Rev. 23 (1997) 3\u201337. doi:https:\/\/doi.org\/10.1016\/s0169-409x(00)00129-0.","DOI":"10.1016\/S0169-409X(96)00423-1"}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142519311473?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142519311473?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T01:18:37Z","timestamp":1761355117000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386142519311473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":43,"alternative-id":["S1386142519311473"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2019.117757","relation":{},"ISSN":["1386-1425"],"issn-type":[{"type":"print","value":"1386-1425"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"2\u2032-(1H-phenanthro[9,10-d]imidazol-2-yl)-phenyl-4-carboxylic acid N-hydroxysuccinimide ester: A new phenanthroimidazole derivative as a fluorescent probe for medical imaging applications","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2019.117757","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"117757"}}