{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T06:09:37Z","timestamp":1778652577486,"version":"3.51.4"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.saa.2020.118685","type":"journal-article","created":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T01:49:13Z","timestamp":1594000153000},"page":"118685","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Selective bioimaging of cancer cells and detection of HSA with indomethacin-based fluorescent probes"],"prefix":"10.1016","volume":"241","author":[{"given":"Cong","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhua","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weisi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liping","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weibing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junhong","family":"Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2020.118685_bb0005","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3322\/caac.21551","article-title":"Cancer statistics","volume":"69","author":"Siegel","year":"2019","journal-title":"CA-Cancer J. Clin."},{"key":"10.1016\/j.saa.2020.118685_bb0010","doi-asserted-by":"crossref","first-page":"363","DOI":"10.3322\/caac.21565","article-title":"Cancer treatment and survivorship statistics","volume":"69","author":"Miller","year":"2019","journal-title":"CA-Cancer J. Clin."},{"key":"10.1016\/j.saa.2020.118685_bb0015","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1038\/nrc882","article-title":"Molecular imaging of cancer with positron emission tomography","volume":"2","author":"Gambhir","year":"2002","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.saa.2020.118685_bb0020","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1593\/tlo.10139","article-title":"Detection of cancer metastases with a dual-labeled near-infrared\/position emission tomography imaging agent","volume":"3","author":"Sampath","year":"2010","journal-title":"Transl. Oncol."},{"key":"10.1016\/j.saa.2020.118685_bb0025","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1016\/S0959-8049(02)00387-8","article-title":"Magnetic resonance imaging in cancer research","volume":"38","author":"Ross","year":"2002","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.saa.2020.118685_bb0030","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1093\/rpd\/ncq012","article-title":"Development of high-resolution molecular phase-contrast stereoscopic X-ray imaging for accurate cancer diagnostics","volume":"139","author":"Zhou","year":"2010","journal-title":"Radiat. Prot. Dosim."},{"key":"10.1016\/j.saa.2020.118685_bb0035","article-title":"Role of glutathione in cancer progression and chemoresistance","volume":"972913","author":"Traverso","year":"2013","journal-title":"Oxidative Med. Cell. Longev."},{"key":"10.1016\/j.saa.2020.118685_bb0040","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.semcdb.2017.12.011","article-title":"Secretory microRNAs as biomarkers of cancer","volume":"78","author":"Kai","year":"2017","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.saa.2020.118685_bb0045","doi-asserted-by":"crossref","first-page":"6657","DOI":"10.1158\/0008-5472.CAN-05-3624","article-title":"Overexpression of cox-2 in human osteosarcoma cells decreases proliferation and increases apoptosis","volume":"66","author":"Xu","year":"2006","journal-title":"Cancer Res."},{"key":"10.1016\/j.saa.2020.118685_bb0050","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1126\/science.1165395","article-title":"Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer","volume":"322","author":"Varambally","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.saa.2020.118685_bb0055","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.snb.2019.03.119","article-title":"A red-emitting fluorescence turn-on probe for the discrimination of cysteine from biothiols and its bioimaging applications in living cells","volume":"290","author":"Jiao","year":"2019","journal-title":"Sensors Actuators B Chem."},{"key":"10.1016\/j.saa.2020.118685_bb0060","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1002\/anie.201710727","article-title":"Near-infrared fluorescent molecular probe for sensitive imaging of keloid","volume":"57","author":"Miao","year":"2018","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.saa.2020.118685_bb0065","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.talanta.2018.07.018","article-title":"A mitochondria-targeted near infrared ratiometric fluorescent probe for the detection of sulfite in aqueous and in living cells","volume":"189","author":"Yao","year":"2018","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2020.118685_bb0070","doi-asserted-by":"crossref","first-page":"11203","DOI":"10.1021\/acs.analchem.7b03724","article-title":"Mitochondrion-targeting, environment-sensitive red fluorescent probe for highly sensitive detection and imaging of vicinal dithiol-containing proteins","volume":"89","author":"Liu","year":"2017","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2020.118685_bb0075","doi-asserted-by":"crossref","first-page":"6432","DOI":"10.1039\/C7CC03587J","article-title":"A fluorescence turn-on probe for human (bovine) serum albumin based on the hydrolysis of a dioxaborine group promoted by proteins","volume":"53","author":"Sun","year":"2017","journal-title":"Chem. Commun."},{"key":"10.1016\/j.saa.2020.118685_bb0080","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1002\/asia.201600012","article-title":"A lysosome-targeting fluorescence off-on probe for imaging of nitroreductase and hypoxia in live cells","volume":"11","author":"Zhou","year":"2016","journal-title":"Chem. Asian J."},{"key":"10.1016\/j.saa.2020.118685_bb0085","doi-asserted-by":"crossref","first-page":"11213","DOI":"10.1039\/C7CC05043G","article-title":"A BODIPY-based two-photon fluorescent probe validates tyrosinase activity in live cells","volume":"53","author":"Naidu Bobba","year":"2017","journal-title":"Chem. Commun."},{"key":"10.1016\/j.saa.2020.118685_bb0090","doi-asserted-by":"crossref","first-page":"11403","DOI":"10.1021\/acs.analchem.9b02759","article-title":"Efficient DNA-catalyzed porphyrin metalation for fluorescent ratiometric Pb2+ detection","volume":"91","author":"Peng","year":"2019","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2020.118685_bb0095","doi-asserted-by":"crossref","first-page":"4331","DOI":"10.1021\/acs.analchem.8b03924","article-title":"Copper ion fluorescent probe based on Zr-MOFs composite material","volume":"91","author":"Chen","year":"2019","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2020.118685_bb0100","doi-asserted-by":"crossref","first-page":"3171","DOI":"10.1021\/jacs.8b12820","article-title":"Rational design of near-infrared aggregation-induced-emission-active probes: in situ mapping of amyloid-\u03b2 plaques with ultrasensitivity and high-fidelity","volume":"141","author":"Fu","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.saa.2020.118685_bb0105","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.snb.2019.02.029","article-title":"Thiol-activated fluorescent probe for sensitive detection and imaging of proteins","volume":"287","author":"Du","year":"2019","journal-title":"Sensors Actuators B Chem."},{"key":"10.1016\/j.saa.2020.118685_bb0110","doi-asserted-by":"crossref","first-page":"7874","DOI":"10.1039\/C9NJ01473J","article-title":"An AIE-based self-assembled fluorescent probe for COX-2 imaging","volume":"43","author":"Cao","year":"2019","journal-title":"New J. Chem."},{"key":"10.1016\/j.saa.2020.118685_bb0115","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1021\/bc300693w","article-title":"Design, synthesis, and structure\u2013activity relationship studies of fluorescent inhibitors of cycloxygenase-2 as targeted optical imaging agents","volume":"24","author":"Uddin","year":"2013","journal-title":"Bioconjug. Chem."},{"key":"10.1016\/j.saa.2020.118685_bb0120","doi-asserted-by":"crossref","first-page":"3618","DOI":"10.1158\/0008-5472.CAN-09-2664","article-title":"Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents","volume":"70","author":"Uddin","year":"2010","journal-title":"Cancer Res."},{"key":"10.1016\/j.saa.2020.118685_bb0125","doi-asserted-by":"crossref","first-page":"5187","DOI":"10.1021\/acs.analchem.7b05337","article-title":"Celecoxib conjugated fluorescent probe for identification and discrimination of cyclooxygenase-2 enzyme in cancer cells","volume":"90","author":"Gurram","year":"2018","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2020.118685_bb0130","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1039\/C4CC08915D","article-title":"A Nile blue based infrared fluorescent probe: imaging tumors that over-express cyclooxygenase-2","volume":"51","author":"Wang","year":"2015","journal-title":"Chem. Commun."},{"key":"10.1016\/j.saa.2020.118685_bb0135","doi-asserted-by":"crossref","first-page":"17469","DOI":"10.1021\/ja4085308","article-title":"Fluorescence discrimination of cancer from inflammation by molecular response to COX-2 enzymes","volume":"135","author":"Zhang","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.saa.2020.118685_bb0140","doi-asserted-by":"crossref","first-page":"11663","DOI":"10.1021\/ja4056905","article-title":"An off\u2013on COX-2-specific fluorescent probe: targeting the Golgi apparatus of cancer cells","volume":"135","author":"Zhang","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.saa.2020.118685_bb0145","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.dyepig.2017.11.053","article-title":"COX-2 targeting indomethacin conjugated fluorescent probe","volume":"150","author":"Kim","year":"2018","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.saa.2020.118685_bb0150","doi-asserted-by":"crossref","first-page":"9965","DOI":"10.1039\/C6CC04255D","article-title":"Indomethacin-guided cancer selective prodrug conjugate activated by histone deacetylase and tumour-associated protease","volume":"52","author":"Jang","year":"2016","journal-title":"Chem. Commun."},{"key":"10.1016\/j.saa.2020.118685_bb0155","doi-asserted-by":"crossref","first-page":"5971","DOI":"10.1021\/acs.analchem.6b00993","article-title":"Assessment of binding affinity between drugs and human serum albumin using nanoporous anodic alumina photonic crystals","volume":"88","author":"Nemati","year":"2016","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2020.118685_bb0160","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1007\/s10953-012-9809-4","article-title":"Interaction of human serum albumin with indomethacin: spectroscopic and molecular modeling studies","volume":"41","author":"Zhang","year":"2012","journal-title":"J. Solut. Chem."},{"key":"10.1016\/j.saa.2020.118685_bb0165","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1039\/C5CC08217J","article-title":"A TICT based NIR-fluorescent probe for human serum albumin: a pre-clinical diagnosis in blood serum","volume":"52","author":"Reja","year":"2016","journal-title":"Chem. Commun."},{"key":"10.1016\/j.saa.2020.118685_bb0170","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.dyepig.2018.01.033","article-title":"An environment-sensitive fluorescent probe for quantification of human serum albumin: design, sensing mechanism, and its application in clinical diagnosis of hypoalbuminemia","volume":"152","author":"Luo","year":"2018","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.saa.2020.118685_bb0175","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.cardfail.2011.02.010","article-title":"Human serum albumin in the clinical syndrome of heart failure","volume":"17","author":"Arques","year":"2011","journal-title":"J. Card. Fail."},{"key":"10.1016\/j.saa.2020.118685_bb0180","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ejim.2018.04.014","article-title":"Human serum albumin in cardiovascular diseases","volume":"52","author":"Arques","year":"2018","journal-title":"Eur. J. Int. Med."},{"key":"10.1016\/j.saa.2020.118685_bb0185","doi-asserted-by":"crossref","first-page":"4648","DOI":"10.1039\/C5AN00585J","article-title":"Discrimination between streptavidin and avidin with fluorescent affinity-based probes","volume":"140","author":"Sun","year":"2015","journal-title":"Analyst"},{"key":"10.1016\/j.saa.2020.118685_bb0190","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1021\/mp500051f","article-title":"Binding and molecular dynamics studies of 7-hydroxycoumarin derivatives with human serum albumin and its pharmacological importance","volume":"11","author":"Yeggoni","year":"2014","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.saa.2020.118685_bb0195","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.snb.2017.03.051","article-title":"Recognition and quantification of HSA: a fluorescence probe across \u03b1-helices of site I and site II","volume":"247","author":"Shen","year":"2017","journal-title":"Sensors Actuators B Chem."},{"key":"10.1016\/j.saa.2020.118685_bb0200","doi-asserted-by":"crossref","first-page":"10793","DOI":"10.1021\/ja8031289","article-title":"Characterization of subdomain IIA binding site of human serum albumin in its native, unfolded, and refolded states using small molecular probes","volume":"130","author":"Abou-Zied","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.saa.2020.118685_bb0205","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1016\/S0026-895X(25)10855-9","article-title":"Further characterization of specific drug binding sites on human serum albumin","volume":"12","author":"Sudlow","year":"1976","journal-title":"Mol. Pharmacol."}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142520306648?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142520306648?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T01:26:57Z","timestamp":1761355617000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386142520306648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":41,"alternative-id":["S1386142520306648"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2020.118685","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Selective bioimaging of cancer cells and detection of HSA with indomethacin-based fluorescent probes","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2020.118685","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"118685"}}