{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T06:54:20Z","timestamp":1782456860580,"version":"3.54.5"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.saa.2020.118853","type":"journal-article","created":{"date-parts":[[2020,8,19]],"date-time":"2020-08-19T12:56:32Z","timestamp":1597841792000},"page":"118853","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"special_numbering":"C","title":["Smart UV spectrophotometric methods based on simple mathematical filtration for the simultaneous determination of celecoxib and ramipril in their pharmaceutical mixtures with amlodipine: A comparative statistical study"],"prefix":"10.1016","volume":"244","author":[{"given":"Khaled","family":"Attala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Elsonbaty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2020.118853_bb0005","first-page":"648","article-title":"Spectrophotometric absorbance correction method for the estimation of tazobactam and cefepime in combined tablet dosage forms","volume":"7","author":"Kant","year":"2015","journal-title":"J. Chem. Pharm. Res."},{"key":"10.1016\/j.saa.2020.118853_bb0010","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1089\/rej.2017.1917","article-title":"Knee osteoarthritis and risk of hypertension: a longitudinal cohort study","volume":"21","author":"Veronese","year":"2018","journal-title":"Rejuvenation Res."},{"key":"10.1016\/j.saa.2020.118853_bb0015","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/eci.12413","article-title":"Cardiovascular disease and osteoarthritis: common pathways and patient outcomes","volume":"45","author":"Fernandes","year":"2015","journal-title":"Eur. J. Clin. Investig."},{"key":"10.1016\/j.saa.2020.118853_bb0020","doi-asserted-by":"crossref","first-page":"228","DOI":"10.5114\/reum.2018.77974","article-title":"Comorbidities in rheumatic arthritis","volume":"56","author":"K\u0142odzi\u0144ski","year":"2018","journal-title":"Reumatologia."},{"key":"10.1016\/j.saa.2020.118853_bb0025","first-page":"866","article-title":"Hypertoniebedingte endorgansch\u00e4den","volume":"107","author":"Schmieder","year":"2010","journal-title":"Dtsch. Arztebl."},{"key":"10.1016\/j.saa.2020.118853_bb0030","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.rehab.2016.01.006","article-title":"Risk factors and burden of osteoarthritis","volume":"59","author":"Palazzo","year":"2016","journal-title":"Ann. Phys. Rehabil. Med."},{"key":"10.1016\/j.saa.2020.118853_bb0035","article-title":"Association between hypertension and risk of knee osteoarthritis: a meta-analysis of observational studies","volume":"96","author":"Zhang","year":"2017","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.saa.2020.118853_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.clinthera.2008.09.008","article-title":"An 18-week, prospective, randomized, double-blind, multicenter study of amlodipine\/ramipril combination versus amlodipine monotherapy in the treatment of hypertension: the assessment of combination therapy of amlodipine\/ramipril (ATAR) study","author":"Miranda","year":"2008","journal-title":"Clin. Ther."},{"key":"10.1016\/j.saa.2020.118853_bb0045","doi-asserted-by":"crossref","DOI":"10.1556\/OH.2014.30037","article-title":"Persistence on treatment with the fixed combination of ramipril and amlodipine","author":"Simonyi","year":"2014","journal-title":"Orv. Hetil."},{"key":"10.1016\/j.saa.2020.118853_bb0050","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.4103\/0366-6999.181959","article-title":"Benefits of fixed dose combination of ramipril\/amlodipine in hypertensive diabetic patients: a subgroup analysis of RAMONA trial","volume":"129","author":"Simonyi","year":"2016","journal-title":"Chin. Med. J."},{"key":"10.1016\/j.saa.2020.118853_bb0055","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.amjmed.2018.08.027","article-title":"Fixed-dose combination amlodipine\/celecoxib (Consensi) for hypertension and osteoarthritis","volume":"132","author":"Smith","year":"2019","journal-title":"Am. J. Med."},{"key":"10.1016\/j.saa.2020.118853_bb0060","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1080\/17512433.2018.1540299","article-title":"Amlodipine and celecoxib for treatment of hypertension and osteoarthritis pain","volume":"11","author":"Angeli","year":"2018","journal-title":"Expert. Rev. Clin. Pharmacol."},{"key":"10.1016\/j.saa.2020.118853_bb0065","doi-asserted-by":"crossref","first-page":"D1102","DOI":"10.1093\/nar\/gky1033","article-title":"PubChem 2019 update: improved access to chemical data","volume":"47","author":"Kim","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.saa.2020.118853_bb0070","doi-asserted-by":"crossref","DOI":"10.1097\/00004872-200201000-00014","article-title":"Dual mechanism of action of amlodipine in human vascular smooth muscle cells","volume":"20","author":"Stepien","year":"2002","journal-title":"J. Hypertens"},{"key":"10.1016\/j.saa.2020.118853_bb0075","series-title":"Pharmacogenet Genomics., Celecoxib Pathways Pharmacokinet. Pharmacodyn","first-page":"310","volume":"22","author":"Li Gonga","year":"2013"},{"issue":"Suppl. 5","key":"10.1016\/j.saa.2020.118853_bb0080","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S1520-765X(03)90063-0","article-title":"Mechanisms of cardiovascular risk reduction with ramipril: Insights from HOPE and HOPE substudies","author":"Lonn","year":"2003","journal-title":"Eur. Hear. Journal"},{"key":"10.1016\/j.saa.2020.118853_bb0085","first-page":"48","volume":"2","author":"Pathak","year":"2017","journal-title":"UV spectroscopic method for simultaneous estimation of celecoxib and amlodipine"},{"key":"10.1016\/j.saa.2020.118853_bb0090","first-page":"1","article-title":"Development of UV spectrophotometry methods for concurrent quantification of amlodipine and celecoxib by manipulation of ratio spectra in pure and pharmaceutical formulation","volume":"14","author":"Attimarad","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.saa.2020.118853_bb0095","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/8202160","article-title":"Development of UV spectrophotometric procedures for determination of amlodipine and celecoxib in formulation: use of scaling factor to improve the sensitivity","volume":"2019","author":"Attimarad","year":"2019","journal-title":"J. Spectrosc."},{"key":"10.1016\/j.saa.2020.118853_bb0100","series-title":"Novel UV Spectrophotometer Methods for Quantitative Estimation of","first-page":"651","volume":"9","author":"Kushwaha","year":"2019"},{"key":"10.1016\/j.saa.2020.118853_bb0105","doi-asserted-by":"crossref","first-page":"104365","DOI":"10.1016\/j.microc.2019.104365","article-title":"Validation of rapid RP-HPLC method for concurrent quantification of amlodipine and celecoxib in pure and formulation using an experimental design","volume":"152","author":"Attimarad","year":"2020","journal-title":"Microchem. J."},{"key":"10.1016\/j.saa.2020.118853_bb0110","doi-asserted-by":"crossref","first-page":"118533","DOI":"10.1016\/j.saa.2020.118533","article-title":"An enhanced first derivative synchronous spectrofluorimetric method for determination of the newly co-formulated drugs, amlodipine and celecoxib in pharmaceutical preparation and human plasma","volume":"240","author":"Attala","year":"2020","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2020.118853_bb0115","first-page":"667","article-title":"Simultaneous estimation of amlodipine besylate and ramipril in tablets dosage form by UV spectrophotometric method","volume":"11","author":"Kumar","year":"2019","journal-title":"J. Pharm. Sci. Res."},{"key":"10.1016\/j.saa.2020.118853_bb0120","doi-asserted-by":"crossref","first-page":"467","DOI":"10.33945\/SAMI\/CHEMM.2020.4.8","article-title":"Simultaneous determination of ramipril and amlodipine besylate in tablet dosage form by first order derivative spectrophotometric method","volume":"4","author":"Patel","year":"2020","journal-title":"Chem. Methodol."},{"key":"10.1016\/j.saa.2020.118853_bb0125","first-page":"160","article-title":"Simultaneous estimation of ramipril and amlodipine in bulk and tablet dosage form by RP-HPLC method","volume":"2","author":"Rajput","year":"2012","journal-title":"J. Appl. Pharm. Sci."},{"key":"10.1016\/j.saa.2020.118853_bb0130","first-page":"725","article-title":"RP-HPLC method development and validation for the simultaneous estimation of ramipril and amlodipine besylate in capsule dosage form","volume":"6","author":"Patel","year":"2014","journal-title":"J. Chem. Pharm. Res."},{"key":"10.1016\/j.saa.2020.118853_bb0135","first-page":"4177","article-title":"Simultaneous determination of amlodipine and ramipril by high performance thin layer chromatography","volume":"19","author":"Gupta","year":"2007","journal-title":"Asian J. Chem."},{"key":"10.1016\/j.saa.2020.118853_bb0140","doi-asserted-by":"crossref","first-page":"4006","DOI":"10.1039\/C9AY01232J","article-title":"Fast and sensitive simultaneous determination of antihypertensive drugs amlodipine besylate and ramipril using an electrochemical method: application to pharmaceuticals and blood serum samples","volume":"11","author":"Moraes","year":"2019","journal-title":"Anal. Methods"},{"key":"10.1016\/j.saa.2020.118853_bb0145","doi-asserted-by":"crossref","first-page":"27511","DOI":"10.1149\/1945-7111\/ab68cd","article-title":"Highly sensitive and selective electrochemical sensor based on Polyglycine modified glassy carbon electrode for simultaneous determination of amlodipine and Ramipril from biological samples","volume":"167","author":"Doulache","year":"2020","journal-title":"J. Electrochem. Soc."},{"key":"10.1016\/j.saa.2020.118853_bb0150","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1039\/C7NJ03124F","article-title":"Construction of a sensitive non-enzymatic fructose carbon paste electrode-CuO nanoflower: designing the experiments by response surface methodology","volume":"42","author":"Amani-Beni","year":"2018","journal-title":"New J. Chem."},{"key":"10.1016\/j.saa.2020.118853_bb0155","doi-asserted-by":"crossref","first-page":"14247","DOI":"10.1039\/C6RA28603H","article-title":"A zeolite modified carbon paste electrode based on copper exchanged clinoptilolite nanoparticles for voltammetric determination of metronidazole","volume":"7","author":"Shahnazari-Shahrezaie","year":"2017","journal-title":"RSC Adv."},{"key":"10.1016\/j.saa.2020.118853_bb0160","doi-asserted-by":"crossref","first-page":"8334","DOI":"10.1016\/j.electacta.2011.07.013","article-title":"Surfactant modified zeolite carbon paste electrode (SMZ-CPE) as a nitrate selective electrode","volume":"56","author":"Nezamzadeh-Ejhieh","year":"2011","journal-title":"Electrochim. Acta"},{"key":"10.1016\/j.saa.2020.118853_bb0165","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.talanta.2011.10.032","article-title":"Voltammetric determination of cysteine using carbon paste electrode modified with Co(II)-Y zeolite","volume":"88","author":"Nezamzadeh-Ejhieh","year":"2012","journal-title":"Talanta."},{"key":"10.1016\/j.saa.2020.118853_bb0170","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1016\/j.jiec.2013.03.018","article-title":"Modification of clinoptilolite nano-particles with hexadecylpyridynium bromide surfactant as an active component of Cr(VI) selective electrode","volume":"19","author":"Nezamzadeh-Ejhieh","year":"2013","journal-title":"J. Ind. Eng. Chem."},{"key":"10.1016\/j.saa.2020.118853_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijhydene.2020.05.019","article-title":"Photodegradation of sulfasalazine over Cu2O-BiVO4-WO3 nano-composite: characterization and experimental design","author":"Omrani","year":"2020","journal-title":"Int. J. Hydrog. Energy"},{"key":"10.1016\/j.saa.2020.118853_bb0180","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.saa.2016.02.028","article-title":"Different spectrophotometric methods applied for the analysis of binary mixture of flucloxacillin and amoxicillin: a comparative study","volume":"161","author":"Attia","year":"2016","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2020.118853_bb0185","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.saa.2015.03.038","article-title":"Different approaches in manipulating ratio spectra applied for the analysis of Cefprozil in presence of its alkaline-induced degradation product: a comparative study","volume":"145","author":"Attia","year":"2015","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2020.118853_bb0190","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.saa.2015.10.040","article-title":"Zero order and signal processing spectrophotometric techniques applied for resolving interference of metronidazole with ciprofloxacin in their pharmaceutical dosage form","volume":"154","author":"Attia","year":"2016","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2020.118853_bb0195","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.saa.2016.01.026","article-title":"Stability indicating methods for the analysis of cefprozil in the presence of its alkaline induced degradation product","volume":"159","author":"Attia","year":"2016","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2020.118853_bb0200","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.saa.2016.01.056","article-title":"Stability-indicating methods for the analysis of ciprofloxacin in the presence of its acid induced degradation product: a comparative study","volume":"159","author":"Attia","year":"2016","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2020.118853_bb0205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.saa.2017.08.066","article-title":"Different spectrophotometric methods applied for the analysis of simeprevir in the presence of its oxidative degradation product: a comparative study","volume":"190","author":"Attia","year":"2018","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2020.118853_bb0210","doi-asserted-by":"crossref","first-page":"118415","DOI":"10.1016\/j.saa.2020.118415","article-title":"Analysis of quinary therapy targeting multiple cardiovascular diseases using UV spectrophotometry and chemometric tools","volume":"238","author":"Elsonbaty","year":"2020","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2020.118853_bb0215","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.saa.2016.07.016","article-title":"Firefly algorithm versus genetic algorithm as powerful variable selection tools and their effect on different multivariate calibration models in spectroscopy: a comparative study","volume":"170","author":"Attia","year":"2017","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2020.118853_bb0220","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.saa.2015.11.024","article-title":"Effect of genetic algorithm as a variable selection method on different chemometric models applied for the analysis of binary mixture of amoxicillin and flucloxacillin: a comparative study","volume":"156","author":"Attia","year":"2016","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2020.118853_bb0225","doi-asserted-by":"crossref","first-page":"335","DOI":"10.4155\/bio-2019-0293","article-title":"Separation-free spectrophotometric platforms for rapid assessment of combined antiplatelet therapy in complex matrices","volume":"12","author":"Elsonbaty","year":"2020","journal-title":"Bioanalysis."},{"key":"10.1016\/j.saa.2020.118853_bb0230","doi-asserted-by":"crossref","first-page":"106","DOI":"10.4103\/2229-4708.103891","article-title":"Absorbance correction method for estimation of telmisartan and metoprolol succinate in combined tablet dosage forms","volume":"3","author":"Patel","year":"2012","journal-title":"Pharm. Methods."},{"key":"10.1016\/j.saa.2020.118853_bb0235","doi-asserted-by":"crossref","first-page":"40","DOI":"10.22159\/ijpps.2016v8i10.13537","article-title":"Recent development in ultraviolet spectrophotometry through the last decade (2006\u20132016): a review","volume":"8","author":"Lotfy","year":"2016","journal-title":"Int J Pharm Pharm Sci"},{"key":"10.1016\/j.saa.2020.118853_bb0240","first-page":"348","article-title":"A review on UV spectrophotometric methods for simultaneous multicomponent analysis","volume":"3","author":"E.-M","year":"2016","journal-title":"Eur. J. Pharm. Med. Res."},{"key":"10.1016\/j.saa.2020.118853_bb0245","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1021\/ac00232a034","article-title":"Fourier transforms in the computation of self-deconvoluted and first-order derivative spectra of overlapped band contours","volume":"53","author":"Kaupplnen","year":"1981","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2020.118853_bb0250","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1366\/0003702814732634","article-title":"Fourier self-deconvolution: a method for resolving intrinsically overlapped bands","volume":"35","author":"Kauppinen","year":"1981","journal-title":"Appl. Spectrosc."},{"key":"10.1016\/j.saa.2020.118853_bb0255","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/9781118971147.ch5","article-title":"Q2(R1) validation of analytical procedures","volume":"2","author":"Borman","year":"2017","journal-title":"ICH Qual. Guidel."}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142520308325?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142520308325?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T01:31:51Z","timestamp":1761355911000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386142520308325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":51,"alternative-id":["S1386142520308325"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2020.118853","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Smart UV spectrophotometric methods based on simple mathematical filtration for the simultaneous determination of celecoxib and ramipril in their pharmaceutical mixtures with amlodipine: A comparative statistical study","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2020.118853","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"118853"}}