{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T11:14:02Z","timestamp":1772882042975,"version":"3.50.1"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.saa.2021.119607","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T20:22:33Z","timestamp":1614025353000},"page":"119607","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Single-cell Raman micro-spectroscopy for tracking of carotenoids in cyanobacteria exposed to Mn and Zn doped ferrite nanoparticles"],"prefix":"10.1016","volume":"254","author":[{"given":"Fran","family":"Nekvapil","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Bunge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucian","family":"Barbu Tudoran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Cint\u0103 Pinzaru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2021.119607_b0005","first-page":"99","article-title":"Cyanobacteria detection and Raman spectroscopy characterization with a highly sensitive, high resolution fiber optic portable Raman system","volume":"61","author":"Cint\u0103 Pinzaru","year":"2016","journal-title":"Studia UBB Phys."},{"key":"10.1016\/j.saa.2021.119607_b0010","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1002\/jrs.4713","article-title":"New SERS feature of \u03b2-carotene: consequence for quantitative SERS analysis","volume":"46","author":"Cint\u0103 Pinzaru","year":"2015","journal-title":"J. Raman Spectrosc."},{"key":"10.1016\/j.saa.2021.119607_b0015","doi-asserted-by":"crossref","first-page":"42899","DOI":"10.1039\/C6RA04255D","article-title":"Live diatoms facing Ag nanoparticles: surface enhanced Raman scattering of bulk cylindrotheca closterium pennate diatoms and of the single cells","volume":"6","author":"Cint\u0103 Pinzaru","year":"2016","journal-title":"RSC Adv."},{"key":"10.1016\/j.saa.2021.119607_b0020","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1039\/C8AY02580K","article-title":"Biogeochemical specificity of adjacent natural carbonated spring waters from Swiss Alps promptly revealed by SERS and Raman technology","volume":"11","author":"Cint\u0103 Pinzaru","year":"2019","journal-title":"Anal. Meth."},{"key":"10.1016\/j.saa.2021.119607_b0025","series-title":"Air and water components of the environment","doi-asserted-by":"crossref","first-page":"27","DOI":"10.24193\/AWC2018_04","article-title":"Comparative Raman spectroscopy study of the coelomic fluid of grazing sea urchins and their native seawater: prospect for a potential indicator of environmental aggression","author":"Nekvapil","year":"2018"},{"key":"10.1016\/j.saa.2021.119607_b0030","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.talanta.2014.06.059","article-title":"Amnesic shellfish poisoning biotoxin detection in seawater using pure or amino-functionalized Ag nanoparticles and SERS","volume":"130","author":"M\u00fcller","year":"2014","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2021.119607_b0035","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.talanta.2018.05.006","article-title":"Lipophilic marine biotoxins SERS sensing in solutions and in mussel tissue","volume":"187","author":"Cint\u0103 Pinzaru","year":"2018","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2021.119607_b0040","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1366\/000370208784909580","article-title":"Characterization of the Ag Mediated Surface-Enhanced Raman Spectroscopy of Saxitoxin","volume":"62","author":"Pearman","year":"2008","journal-title":"Appl. Spectrosc."},{"key":"10.1016\/j.saa.2021.119607_b0045","first-page":"29","article-title":"Zinc ferrite nanoparticles as perspective functional materials for applications in casting technologies","volume":"56","author":"Kmita","year":"2017","journal-title":"Metalurgija"},{"key":"10.1016\/j.saa.2021.119607_b0050","first-page":"69","article-title":"Application of magnetic chitosan composites for the removal of toxic metals and dyes from aqueous solutions","volume":"201\u2013202","author":"Reddy","year":"2013","journal-title":"J. Appl. Colloid Interface Sci."},{"key":"10.1016\/j.saa.2021.119607_b0055","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1515\/amm-2016-0289","article-title":"Use of specific properties of zinc ferrite in innovative technologies","volume":"61","author":"Kmita","year":"2016","journal-title":"Arch. Metall. Mater."},{"key":"10.1016\/j.saa.2021.119607_b0060","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1002\/jrs.5852","article-title":"Raman spectra tell us so much more: Raman features and saturation magnetization for efficient analysis of manganese zinc ferrite nanoparticles","volume":"51","author":"Nekvapil","year":"2020","journal-title":"J. Raman Spectrosc."},{"key":"10.1016\/j.saa.2021.119607_b0065","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1264\/jsme2.ME11126","article-title":"Oxidative Stress Induced in Microorganisms by Zero-valent Iron Nanoparticles","volume":"26","author":"\u0160evc\u016f","year":"2011","journal-title":"Microbes Environ."},{"key":"10.1016\/j.saa.2021.119607_b0070","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jcis.2013.05.061","article-title":"Exopolysaccharides protect Synechocystis against the deleterious effects of Titanium dioxide nanoparticles in natural and artificial waters","volume":"405","author":"Planchon","year":"2013","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.saa.2021.119607_b0075","doi-asserted-by":"crossref","first-page":"8522","DOI":"10.1021\/acs.jafc.8b01522","article-title":"Phycobiliproteins production enhancement and lipidomic alteration by titanium dioxide nanoparticles in Synechocystis sp. PCC 6803 culture","volume":"66","author":"Zahra","year":"2018","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.saa.2021.119607_b0080","doi-asserted-by":"crossref","first-page":"871","DOI":"10.3390\/ijms16010871","article-title":"Responses to Oxidative and Heavy Metal Stresses in Cyanobacteria: Recent Advances","volume":"16","author":"Cassier-Chauvat","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.saa.2021.119607_b0085","doi-asserted-by":"crossref","first-page":"2970","DOI":"10.1021\/jf970010s","article-title":"Importance of Carotenoid Structure in Radical-Scavenging Reactions","volume":"45","author":"Mortensen","year":"1997","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.saa.2021.119607_b0090","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3390\/ijms17010103","article-title":"Free radical scavenging and cellular antioxidant properties of astaxanthin","volume":"17","author":"Dose","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.saa.2021.119607_b0095","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0168-9452(01)00364-8","article-title":"Iron-dependent oxidative stress in Chlorella vulgaris","volume":"161","author":"Estevez","year":"2001","journal-title":"Plant Sci."},{"key":"10.1016\/j.saa.2021.119607_b0100","article-title":"Subcellular Localization of Carotenoid Biosynthesis in Synechocystis sp. PCC 6803","volume":"10","author":"Zhang","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.saa.2021.119607_b0105","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.abb.2004.03.018","article-title":"Water soluble carotenoid proteins of cyanobacteria","volume":"430","author":"Kerfeld","year":"2004","journal-title":"Archiv. Biochem. Biophys."},{"key":"10.1016\/j.saa.2021.119607_b0110","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.bbabio.2015.05.010","article-title":"Echinenone vibrational properties: From solvents to the orange carotenoid protein","volume":"1847","author":"Kish","year":"2015","journal-title":"Biochim. Biophys. Acta - Bioenergetics"},{"key":"10.1016\/j.saa.2021.119607_b0115","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1128\/aem.59.3.867-873.1993","article-title":"Enhanced Carotenoid Biosynthesis by Oxidative Stress in Acetate-Induced Cyst Cells of a Green Unicellular Alga, Haematococcus pluvialis","volume":"59","author":"Kobayashi","year":"1993","journal-title":"Appl. Environ. Microbiol."},{"issue":"F4","key":"10.1016\/j.saa.2021.119607_b0120","first-page":"F4.3.1.","article-title":"Chlorophylls and Carotenoids: Measurement and Characterization by UV-VIS Spectroscopy","volume":"1","author":"Lichtenthaler","year":"2001","journal-title":"Curr. Protoc. Food Anal. Chem."},{"issue":"9","key":"10.1016\/j.saa.2021.119607_b0125","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0137645","article-title":"Spectrophotometric Analysis of Pigments: A Critical Assessment of a High-Throughput Method for Analysis of Algal Pigment Mixtures by Spectral Deconvolution","volume":"10","author":"Thrane","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.saa.2021.119607_b0130","doi-asserted-by":"crossref","unstructured":"Flores-Hidalgo, M., Torres-Rivas, F., Monzon-Bensojo, J., Escobedo-Bretado, M., Glossman-Mitnik, D., Barraza-Jimenez, D. Electronic Structure of Carotenoids in Natural and Artificial Photosynthesis. In: Cvetkovic, D.J., Nikolic, G.S. (eds.) Carotenoids. IntechOpen, 2017 pages Chapter doi: 10.5772\/67636.","DOI":"10.5772\/67636"},{"key":"10.1016\/j.saa.2021.119607_b0135","first-page":"372","article-title":"Potential and limits of Raman spectroscopy for carotenoid detection in microorganisms: implications for astrobiology","volume":"4","author":"Jehlicka","year":"2014","journal-title":"Phil. Trans. R. Soc. A"},{"key":"10.1016\/j.saa.2021.119607_b0140","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.3390\/md9061101","article-title":"Carotenoids in Algae: Distribution, Biosyntheses and Functions","volume":"9","author":"Takaichi","year":"2011","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.saa.2021.119607_bib186","doi-asserted-by":"crossref","first-page":"3292","DOI":"10.1128\/JB.00050-09","article-title":"The biosynthetic pathway for myxol-2\u2019 fucoside (myxoxanthophyll) in the cyanobacterium Synechococcus sp. strain PCC 7002","volume":"191","author":"Graham","year":"2009","journal-title":"Journal of Bacteriology"},{"key":"10.1016\/j.saa.2021.119607_b0150","doi-asserted-by":"crossref","unstructured":"K. Gundermann, C. B\u00fcchel, Structure and functional heterogeneity of fucoxanthin-chlorophyll proteins. In diatoms. In The Structural Basis of Biological Energy Generation; Hohmann-Marriott, M. F., Ed.; Springer Science+Business Media: Dordrecht, Netherlands, 2014, pp. 21-37.","DOI":"10.1007\/978-94-017-8742-0_2"},{"key":"10.1016\/j.saa.2021.119607_b0155","doi-asserted-by":"crossref","unstructured":"F. Nekvapil, I. Breze\u015ftean, S. Tom\u0161i\u0107, C.S. M\u00fcller, V. Chi\u015f, S. Cint\u0103 Pinzaru, Microsphere packages of carotenoids: intact sea urchin eggs tracked by Paman spectroscopy tools, Photochem. Photobiol. Sci. 2019, 18: 1933-1944. doi: 10.1039\/c9pp00181f.","DOI":"10.1039\/c9pp00181f"},{"key":"10.1016\/j.saa.2021.119607_b0160","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.foodchem.2017.09.105","article-title":"Citrus Fruiits Freshness Assessment Using Raman Spectroscopy","volume":"242","author":"Nekvapil","year":"2018","journal-title":"Food Chem."},{"key":"10.1016\/j.saa.2021.119607_b0165","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1002\/jrs.2517","article-title":"Characterization of sodium alginate and its block fractions by surface-enhanced Raman spectroscopy","volume":"41","author":"Campos-Vallette","year":"2010","journal-title":"J. Raman Spectrosc."},{"key":"10.1016\/j.saa.2021.119607_b0170","first-page":"125","article-title":"Effects of chromophore orientation and molecule conformation on surface-enhanced Raman scattering studied with alkanoic acids and colloidal silver nanoparticles","author":"Seballos","year":"2006","journal-title":"J. Chem. Phys."},{"key":"10.1016\/j.saa.2021.119607_b0175","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/jmr.2177","article-title":"Atomic force microscopy characterization of silver nanoparticles interactions with marine diatom cells and extracellular polymeric substance","volume":"25","author":"Pletikapi\u0107","year":"2012","journal-title":"J. Mol. Recognit."},{"key":"10.1016\/j.saa.2021.119607_b0180","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1515\/aiht-2017-68-3054","article-title":"How protein coronas determine the fate of engineered nanoparticles in biological environment","volume":"68","author":"Capjak","year":"2017","journal-title":"Arh. Hig. Rada Toksikol."},{"key":"10.1016\/j.saa.2021.119607_b0185","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s11120-013-9942-y","article-title":"Probing the carotenoid content of intact Cyclotella cells by resonance Raman spectroscopy","volume":"119","author":"Alexandre","year":"2014","journal-title":"Photosynth. Res."}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142521001839?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142521001839?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T01:46:20Z","timestamp":1761356780000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386142521001839"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":37,"alternative-id":["S1386142521001839"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2021.119607","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Single-cell Raman micro-spectroscopy for tracking of carotenoids in cyanobacteria exposed to Mn and Zn doped ferrite nanoparticles","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2021.119607","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"119607"}}