{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T02:07:24Z","timestamp":1761358044794,"version":"build-2065373602"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.saa.2022.120937","type":"journal-article","created":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T03:28:05Z","timestamp":1642994885000},"page":"120937","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Ratiometric fluorescence resonance energy transfer for reliable and sensitive detection of intracellular telomerase RNA via strand displacement reaction amplification"],"prefix":"10.1016","volume":"271","author":[{"given":"Bei","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baoxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2022.120937_b0005","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1126\/science.7544492","article-title":"Functional characterization and developmental regulation of mouse telomerase RNA","volume":"269","author":"Blasco","year":"1995","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.saa.2022.120937_b0010","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.bbcan.2016.10.005","article-title":"Means to the ends: the role of telomeres and telomere processing machinery in metastasis","volume":"1866","author":"Robinson","year":"2016","journal-title":"Biochim Biophys Acta-Rev Cancer"},{"issue":"5228","key":"10.1016\/j.saa.2022.120937_b0015","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1126\/science.7544491","article-title":"The RNA component of human telomerase","volume":"269","author":"Feng","year":"1995","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.saa.2022.120937_b0020","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1136\/jcp.50.2.110","article-title":"Telomerase activity and in situ telomerase RNA expression in malignant and non-malignant lymph nodes","volume":"50","author":"Yashima","year":"1997","journal-title":"Clin Pathol"},{"key":"10.1016\/j.saa.2022.120937_b0025","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1002\/(SICI)1097-0142(19980401)82:7<1319::AID-CNCR15>3.0.CO;2-9","article-title":"Telomerase activity and expression of its RNA component in cervical lesions","volume":"82","author":"Yashima","year":"1998","journal-title":"Cancer"},{"issue":"2","key":"10.1016\/j.saa.2022.120937_b0030","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/path.1191","article-title":"Telomerase as a prognostic marker in breast cancer: high-throughput tissue microarray analysis of hTERT and hTR","volume":"198","author":"Poremba","year":"2002","journal-title":"J Pathol"},{"key":"10.1016\/j.saa.2022.120937_b0035","first-page":"200","article-title":"Hanahan Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis","volume":"12","author":"Blasco","year":"1996","journal-title":"Genet"},{"key":"10.1016\/j.saa.2022.120937_b0040","first-page":"645","article-title":"Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues","volume":"56","author":"Avilion","year":"1996","journal-title":"Cancer Res"},{"key":"10.1016\/j.saa.2022.120937_b0045","unstructured":"K. Yashima, L.A. Litzky, L. Kaiser, T. Rogers, S. Lam, Wistuba II et al., Telomerase expression in respiratory epithelium during the multistage pathogenesis of lung carcinomas, Cancer Res 57 (1997) 2373-2377. http:\/\/citeseerx.ist.psu.edu\/viewdoc\/download;jsessionid=73EC42907D588B010E27946236C825A1?doi=10.1.1.319.5301&rep=rep1&type=pdf"},{"issue":"2","key":"10.1016\/j.saa.2022.120937_b0050","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/(SICI)1096-9896(199906)188:2<139::AID-PATH344>3.0.CO;2-6","article-title":"Hodgkin and Reed-Sternberg cells of classical Hodgkin's disease overexpress the telomerase RNA template (hTR)","volume":"188","author":"Heine","year":"1999","journal-title":"J. pathol."},{"issue":"9","key":"10.1016\/j.saa.2022.120937_b0055","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/j.febslet.2015.02.035","article-title":"Quantitative assessment of telomerase components in cancer cell lines","volume":"589","author":"Ak\u0131nc\u0131lar","year":"2015","journal-title":"FEBS let."},{"key":"10.1016\/j.saa.2022.120937_b0060","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1039\/c3an36689h","article-title":"Luminescent silver nanoclusters anchored by oligonucleotides detect human telomerase ribonucleic acid template","volume":"138","author":"Wei","year":"2013","journal-title":"Analyst"},{"issue":"10","key":"10.1016\/j.saa.2022.120937_b0065","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1039\/C7AN00150A","article-title":"A dual-colored ratiometric-fluorescent oligonucleotide probe for the detection of human telomerase RNA in cell extracts","volume":"142","author":"Ning","year":"2017","journal-title":"Analyst"},{"issue":"5","key":"10.1016\/j.saa.2022.120937_b0070","doi-asserted-by":"crossref","first-page":"3619","DOI":"10.1021\/acs.analchem.8b05610","article-title":"Concatenated catalytic hairpin assembly\/hyperbranched hybridization chain reaction based enzyme-free signal amplification for the sensitive photoelectrochemical detection of human telomerase RNA","volume":"91","author":"Chu","year":"2019","journal-title":"Anal Chem."},{"key":"10.1016\/j.saa.2022.120937_b0075","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.aca.2020.03.049","article-title":"A pH-responsive colorimetric detection of human telomerase RNA based on a three-dimensional DNA amplifier","volume":"1111","author":"Wang","year":"2020","journal-title":"Anal. Chim. acta"},{"issue":"9","key":"10.1016\/j.saa.2022.120937_b0080","doi-asserted-by":"crossref","first-page":"2727","DOI":"10.1039\/C6AN00233A","article-title":"Sensitive detection of intracellular RNA of human telomerase by using graphene oxide as a carrier to deliver the assembly element of hybridization chain reaction","volume":"141","author":"Shi","year":"2016","journal-title":"Analyst"},{"issue":"19","key":"10.1016\/j.saa.2022.120937_b0085","doi-asserted-by":"crossref","first-page":"9386","DOI":"10.1039\/C8NR01260A","article-title":"Sticky-flares for in situ monitoring of human telomerase RNA in living cells","volume":"10","author":"Wu","year":"2018","journal-title":"Nanoscale"},{"issue":"6","key":"10.1016\/j.saa.2022.120937_b0090","doi-asserted-by":"crossref","first-page":"3829","DOI":"10.1039\/C6SC00377J","article-title":"Fluorescence resonance energy transfer-based hybridization chain reaction for in situ visualization of tumor-related mRNA","volume":"7","author":"Huang","year":"2016","journal-title":"Chem Sci"},{"issue":"1","key":"10.1016\/j.saa.2022.120937_b0095","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jphotochem.2011.12.002","article-title":"Binding interaction between plasma protein bovine serum albumin and flexible charge transfer fluorophore: A spectroscopic study in combination with molecular docking and molecular dynamics simulation","volume":"231","author":"Jana","year":"2012","journal-title":"J. Photoch. Photobio. A"},{"key":"10.1016\/j.saa.2022.120937_b0100","doi-asserted-by":"crossref","unstructured":"R.B. Best, K.A. Merchant, I.V. Gopich, B. Schuler, A. Bax, W.A. Eaton, Effect of flexibility and cis residues in single-molecule FRET studies of polyproline, Proc. Natl. Acad. Sci. USA 104 (2007) 18964. doi: 10.1073pnas.0709567104","DOI":"10.1073\/pnas.0709567104"},{"issue":"10","key":"10.1016\/j.saa.2022.120937_b0105","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1002\/bip.22057","article-title":"Potential charge transfer probe induced conformational changes of model plasma protein human serum albumin: Spectroscopic, molecular docking, and molecular dynamics simulation study","volume":"97","author":"Jana","year":"2012","journal-title":"Biopolymers"},{"issue":"32","key":"10.1016\/j.saa.2022.120937_b0110","doi-asserted-by":"crossref","first-page":"11220","DOI":"10.1021\/ja5029364","article-title":"Activatable fluorescence\/MRI bimodal platform for tumor cell imaging via MnO2 nanosheet-aptamer nanoprobe","volume":"136","author":"Zhao","year":"2014","journal-title":"J Am Chem Soc"},{"issue":"18","key":"10.1016\/j.saa.2022.120937_b0115","doi-asserted-by":"crossref","first-page":"10380","DOI":"10.1039\/D0NR02096F","article-title":"An intelligent nanodevice based on the synergistic effect of telomerase-triggered photodynamic therapy and gene-silencing for precise cancer cell therapy","volume":"12","author":"Yi","year":"2020","journal-title":"Nanoscale"},{"issue":"1","key":"10.1016\/j.saa.2022.120937_b0120","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1039\/C6SC03162E","article-title":"MnO2 nanosheet mediated \u201cDD\u2013A\u201d FRET binary probes for sensitive detection of intracellular mRNA","volume":"8","author":"Ou","year":"2017","journal-title":"Chem Sci"},{"issue":"33","key":"10.1016\/j.saa.2022.120937_b0125","doi-asserted-by":"crossref","first-page":"27681","DOI":"10.1021\/acsami.8b08872","article-title":"Bimodal phosphorescence-magnetic resonance imaging nanoprobes for glutathione based on MnO2 Nanosheet-Ru(II) complex nanoarchitecture","volume":"10","author":"Shi","year":"2018","journal-title":"ACS Appl Mater Inter"},{"issue":"50","key":"10.1016\/j.saa.2022.120937_b0130","doi-asserted-by":"crossref","first-page":"43405","DOI":"10.1021\/acsami.8b15330","article-title":"Novel fluorescence switch for microrna imaging in living cells based on DNAzyme amplification strategy","volume":"10","author":"Li","year":"2018","journal-title":"ACS Appl Mater Inter"},{"issue":"7","key":"10.1016\/j.saa.2022.120937_b0135","doi-asserted-by":"crossref","first-page":"5717","DOI":"10.1021\/acsami.6b13073","article-title":"Biodegradable MnO2 nanosheet-mediated signal amplification in living cells enables sensitive detection of down-regulated intracellular MicroRNA","volume":"9","author":"Li","year":"2017","journal-title":"ACS Appl Mater Inter"},{"issue":"6","key":"10.1016\/j.saa.2022.120937_b0140","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/nmeth.1208","article-title":"A practical guide to single-molecule FRET","volume":"5","author":"Roy","year":"2008","journal-title":"Nat Methods"},{"issue":"1","key":"10.1016\/j.saa.2022.120937_b0145","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/bio.3384","article-title":"Rapid and sensitive colorimetric detection of ascorbic acid in food based on the intrinsic oxidase-like activity of MnO2 nanosheets","volume":"33","author":"He","year":"2018","journal-title":"Luminescence"},{"issue":"16","key":"10.1016\/j.saa.2022.120937_b0150","doi-asserted-by":"crossref","first-page":"5998","DOI":"10.1021\/ja4019572","article-title":"Single-layer MoS2-based nanoprobes for homogeneous detection of biomolecules","volume":"135","author":"Zhu","year":"2013","journal-title":"J Am Chem Soc"},{"issue":"15","key":"10.1016\/j.saa.2022.120937_b0155","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1002\/anie.200804643","article-title":"The chemical biology of aptamers","volume":"48","author":"Mayer","year":"2009","journal-title":"Angew Chem Int Ed"},{"issue":"5","key":"10.1016\/j.saa.2022.120937_b0160","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S1074-5521(96)90113-1","article-title":"Exploiting the potential of antisense: beyond phosphorothioate oligodeoxynucleotides","volume":"3","author":"Stein","year":"1996","journal-title":"Chem Biol"}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142522000853?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142522000853?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T02:02:35Z","timestamp":1761357755000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386142522000853"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":32,"alternative-id":["S1386142522000853"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2022.120937","relation":{},"ISSN":["1386-1425"],"issn-type":[{"type":"print","value":"1386-1425"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ratiometric fluorescence resonance energy transfer for reliable and sensitive detection of intracellular telomerase RNA via strand displacement reaction amplification","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2022.120937","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"120937"}}