{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T07:34:08Z","timestamp":1785569648799,"version":"3.56.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.saa.2022.121024","type":"journal-article","created":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T11:54:55Z","timestamp":1644494095000},"page":"121024","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["A feasible fluorimetric approach anchored in diaryl pyrrolone derivative for the facile analysis of milnacipran in tablets; evaluation of the method greenness"],"prefix":"10.1016","volume":"273","author":[{"given":"Sayed M","family":"Derayea","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoda","family":"Madian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebtihal","family":"Samir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed A","family":"Hamad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled M.","family":"Badr El-Din","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2022.121024_b0005","first-page":"1975","article-title":"Efficacy of milnacipran in patients with fibromyalgia","volume":"32","author":"Gendreau","year":"2005","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.saa.2022.121024_b0010","article-title":"A stability indicating U-HPLC method for milnacipran in bulk drugs and pharmaceutical dosage forms","author":"Naresh","year":"2012","journal-title":"Am. J. Anal. Chem."},{"key":"10.1016\/j.saa.2022.121024_b0015","series-title":"Depression: Causes and Treatment","author":"Beck","year":"2009"},{"key":"10.1016\/j.saa.2022.121024_b0020","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1097\/00004850-199609004-00006","article-title":"Milnacipran and selective serotonin reuptake inhibitors in major depression","volume":"11","author":"Lopez-Ibor","year":"1996","journal-title":"Int. Clin. Psychopharmacol."},{"key":"10.1016\/j.saa.2022.121024_b0025","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/00004850-199609004-00002","article-title":"Preclinical pharmacology of milnacipran","volume":"11","author":"Briley","year":"1996","journal-title":"Int. Clin. Psychopharmacol."},{"key":"10.1016\/j.saa.2022.121024_b0030","first-page":"497","article-title":"Development and validation of UV Spectrophotometric method for quick estimation of milnacipran HCl in dissolution media","volume":"5","author":"Ratnakar","year":"2012","journal-title":"Asian J. Res. Chem."},{"key":"10.1016\/j.saa.2022.121024_b0035","first-page":"429","article-title":"Development and validation of UV Spectrophotometric method for estimation of milnacipran HCl in bulk and tablet dosage form","volume":"5","author":"Ratnakar","year":"2012","journal-title":"Res. J. Pharm. Technol."},{"key":"10.1016\/j.saa.2022.121024_b0040","first-page":"1250","article-title":"Spectrophotometric estimation of milnacipran in pharmaceutical formulation","volume":"4","author":"Kumar","year":"2011","journal-title":"Res. J. Pharm. Technol."},{"issue":"1","key":"10.1016\/j.saa.2022.121024_b0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.12691\/ces-1-1-1","article-title":"Quantitative determination of milnacipran by simple colorimetric methods","volume":"1","author":"Mubarakunnisa","year":"2013","journal-title":"Chem. Eng. Sci."},{"issue":"5","key":"10.1016\/j.saa.2022.121024_b0050","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1007\/s11094-016-1449-3","article-title":"Simple and sensitive colorimetric method for the determination of Milnacipran in bulk and swellable matrix tablets","volume":"50","author":"Hussain","year":"2016","journal-title":"Pharm. Chem. J."},{"issue":"39","key":"10.1016\/j.saa.2022.121024_b0055","doi-asserted-by":"crossref","first-page":"22154","DOI":"10.1039\/C8RA03614D","article-title":"Utility of the chromogenic and fluorogenic properties of benzofurazan for the assay of milnacipran in human urine and plasma","volume":"8","author":"Mostafa","year":"2018","journal-title":"RSC Adv."},{"key":"10.1016\/j.saa.2022.121024_b0060","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.saa.2018.07.040","article-title":"An experimental ninhydrin design approach for the sensitive spectrofluorimetric assay of milnacipran in human urine and plasma","volume":"205","author":"Mostafa","year":"2018","journal-title":"Spectrochim. Acta Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2022.121024_b0065","doi-asserted-by":"crossref","first-page":"38884","DOI":"10.1039\/D0RA05162D","article-title":"A new approach based on isoindole formation reaction for sensitive fluorimetric assay of milnacipran in tablets and biological fluids (plasma\/urine)","volume":"10","author":"Abu-hassan","year":"2020","journal-title":"RSC Adv."},{"key":"10.1016\/j.saa.2022.121024_b0070","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.saa.2019.02.071","article-title":"A new sensitive approach for spectrofluorimetric assay of Milnacipran and Amisulpride in real plasma and pharmaceutical preparations via complexation with Eosin Y dye","volume":"214","author":"Atia","year":"2019","journal-title":"Spectrochim. Acta Part A Mol. Biomol. Spectrosc."},{"issue":"2","key":"10.1016\/j.saa.2022.121024_b0075","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.jchromb.2004.03.063","article-title":"Determination of milnacipran, a serotonin and noradrenaline reuptake inhibitor, in human plasma using liquid chromatography with spectrofluorimetric detection","volume":"806","author":"Puozzo","year":"2004","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.saa.2022.121024_b0080","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2174\/1573412911309020010","article-title":"Development and validation of a stability indicating liquid chromatographic method for the determination of milnacipran in bulk and its formulations","volume":"9","author":"Singhvi","year":"2013","journal-title":"Curr. Pharm. Anal."},{"issue":"1","key":"10.1016\/j.saa.2022.121024_b0085","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1080\/10826076.2012.734002","article-title":"Quantitative determination of milnacipran HCl in rabbit plasma by HPLC and its application to pharmacokinetics study","volume":"37","author":"Parejiya","year":"2014","journal-title":"J. Liq. Chromatogr. Relat. Technol."},{"issue":"5-6","key":"10.1016\/j.saa.2022.121024_b0090","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/S0731-7085(01)00382-X","article-title":"Spectrophotometric and HPTLC-densitometric determination of lisinopril and hydrochlorothiazide in binary mixtures","volume":"25","author":"El-Gindy","year":"2001","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"5","key":"10.1016\/j.saa.2022.121024_b0095","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1556\/JPC.24.2011.5.9","article-title":"Stability-indicating HPTLC method for determination of milnacipran hydrochloride in pharmaceutical formulations","volume":"24","author":"Khatri","year":"2011","journal-title":"JPC-J. Planar Chromatogr.-Modern TLC"},{"issue":"1-2","key":"10.1016\/j.saa.2022.121024_b0100","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1365\/s10337-010-1607-9","article-title":"Determination of milnacipran in human plasma using GC\u2013MS","volume":"72","author":"U\u00e7akt\u00fcrk","year":"2010","journal-title":"Chromatographia"},{"key":"10.1016\/j.saa.2022.121024_b0105","doi-asserted-by":"crossref","first-page":"11746","DOI":"10.1109\/JSEN.2019.2940196","article-title":"All-solid-state disposable polymeric ion selective electrode for determination of milnacipran in pharmaceutical dosage form","volume":"19","author":"Saleh","year":"2019","journal-title":"IEEE Sens. J."},{"key":"10.1016\/j.saa.2022.121024_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2020.104835","article-title":"A review on the use of fluorescamine as versatile and convenient analytical probe","volume":"156","author":"Derayea","year":"2020","journal-title":"Microchem. J."},{"key":"10.1016\/j.saa.2022.121024_b0115","doi-asserted-by":"crossref","first-page":"16269","DOI":"10.1039\/C8RA01617H","article-title":"Switch on fluorescence probe for the selective determination of lisinopril in pharmaceutical formulations: application to content uniformity testing","volume":"8","author":"Mohammed","year":"2018","journal-title":"RSC Adv."},{"key":"10.1016\/j.saa.2022.121024_b0120","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.microc.2019.05.046","article-title":"Diarylpyrrolone based fluorophore for the selective spectrofluorometric method for determination of Linagliptin antidiabetic drug in pharmaceutical tablets","volume":"148","author":"Omar","year":"2019","journal-title":"Microchem. J."},{"key":"10.1016\/j.saa.2022.121024_b0125","doi-asserted-by":"crossref","first-page":"5927","DOI":"10.1021\/ja00771a084","article-title":"Novel reagent for the fluorometric assay of primary amines","volume":"94","author":"Weigele","year":"1972","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.saa.2022.121024_b0130","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/BF02509938","article-title":"Disproportionation of the alkaloid sanguinarine on silica gel","volume":"33","author":"Savina","year":"1999","journal-title":"Pharm. Chem. J."},{"key":"10.1016\/j.saa.2022.121024_b0135","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/0003-9861(74)90490-1","article-title":"Studies on the reaction of fluorescamine with primary amines","volume":"163","author":"De Bernardo","year":"1974","journal-title":"Arch Biochem. Biophys."},{"key":"10.1016\/j.saa.2022.121024_b0140","unstructured":"Validation of Analytical procedures: methodology International Conferenc on Harmonization (ICH) of Technical Requirements for the Registration Pharmaceuticals for Human Use in, Geneva, 1996."},{"key":"10.1016\/j.saa.2022.121024_b0145","doi-asserted-by":"crossref","first-page":"8026","DOI":"10.1016\/j.arabjc.2020.09.032","article-title":"Facile one-pot green solvent synergized fluorescence reaction for determination of doxorubicin in presence of paclitaxel; co-administered drug, application to stability study and analysis in bulk, vial and biological fluids","volume":"13","author":"Derayea","year":"2020","journal-title":"Arabian J. Chem."},{"key":"10.1016\/j.saa.2022.121024_b0150","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.trac.2012.03.013","article-title":"Analytical Eco-Scale for assessing the greenness of analytical procedures","volume":"37","author":"Ga\u0142uszka","year":"2012","journal-title":"TrAC, Trends Anal. Chem."},{"key":"10.1016\/j.saa.2022.121024_b0155","series-title":"Green Analytical Chemistry: Theory and Practice","author":"De La Guardia","year":"2010"}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138614252200172X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138614252200172X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T01:59:24Z","timestamp":1761357564000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S138614252200172X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":31,"alternative-id":["S138614252200172X"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2022.121024","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A feasible fluorimetric approach anchored in diaryl pyrrolone derivative for the facile analysis of milnacipran in tablets; evaluation of the method greenness","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2022.121024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"121024"}}