{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:21:06Z","timestamp":1790036466538,"version":"4.0.1"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81902763"],"award-info":[{"award-number":["81902763"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Shandong Province Natural Science Foundation","doi-asserted-by":"publisher","award":["ZR2023MH131"],"award-info":[{"award-number":["ZR2023MH131"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC3602400"],"award-info":[{"award-number":["2022YFC3602400"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.saa.2025.125753","type":"journal-article","created":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T16:08:49Z","timestamp":1736957329000},"page":"125753","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Lysosomal-targeted fluorescent probe for detecting SO2 derivatives in human umbilical vein endothelial cells"],"prefix":"10.1016","volume":"331","author":[{"given":"Feng","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian-Fang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao-Xiang","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao-Min","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2025.125753_b0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2021.120183","article-title":"A ratiometric and colorimetric fluorescent probe designed based on FRET for detecting SO32\u2212\/HSO3\u2212 in living cells and mice","volume":"263","author":"Shen","year":"2021","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.125753_b0010","doi-asserted-by":"crossref","first-page":"10236","DOI":"10.1039\/C5CC03055B","article-title":"A mitochondria-targeted colorimetric and ratiometric fluorescent probe for biological SO2 derivatives in living cells","volume":"51","author":"Liu","year":"2015","journal-title":"Chem. Commun."},{"key":"10.1016\/j.saa.2025.125753_b0015","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.snb.2017.07.082","article-title":"Fluorescence imaging of SO2 derivatives in Daphnia magna with a mitochondria-targeted two-photon ratiometric fluorescent probe","volume":"254","author":"Li","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"10.1016\/j.saa.2025.125753_b0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2021.120098","article-title":"Diketopyrrolopyrrole-based fluorescent probe for endogenous bisulfite detection and bisulfite triggered phototoxicity specific in liver cancer cells","volume":"262","author":"Wang","year":"2021","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.125753_b0025","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1016\/j.cclet.2018.08.012","article-title":"Recent progress in Michael addition-based fluorescent probes for sulfur dioxide and its derivatives","volume":"29","author":"Xu","year":"2018","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.saa.2025.125753_b0030","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.snb.2012.03.034","article-title":"A novel coumarin-based fluorescent probe for selective detection of bissulfite anions in water and sugar samples","volume":"166\u2013167","author":"Yang","year":"2012","journal-title":"Sens. Actuators, B"},{"key":"10.1016\/j.saa.2025.125753_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2021.109971","article-title":"Construction and evaluation of ratiometric fluorescent probes based on a 7-aminocoumarin scaffold for the detection of SO2 derivatives","volume":"198","author":"Shen","year":"2022","journal-title":"Dyes Pigm."},{"key":"10.1016\/j.saa.2025.125753_b0040","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.freeradbiomed.2019.09.007","article-title":"Recent progress in the small-molecule fluorescent probes for the detection of sulfur dioxide derivatives (HSO3\u2212\/SO32\u2212)","volume":"145","author":"Yang","year":"2019","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.saa.2025.125753_b0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.talanta.2017.08.001","article-title":"A novel colorimetric and fluorescent probe for simultaneous detection of SO32\u2212\/HSO3\u2212 and HSO4\u2212 by different emission channels and its bioimaging in living cells","volume":"176","author":"Yu","year":"2018","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2025.125753_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2022.340721","article-title":"Dual-response and lysosome-targeted fluorescent probe for viscosity and sulfur dioxide derivatives","volume":"1239","author":"Li","year":"2023","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.saa.2025.125753_b0055","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.bbrc.2018.01.103","article-title":"Retina-derived endogenous sulfur dioxide might be a novel anti-apoptotic factor","volume":"496","author":"Du","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.saa.2025.125753_b0060","doi-asserted-by":"crossref","first-page":"4232","DOI":"10.1039\/C8TB01152D","article-title":"Dual-site lysosome-targeted fluorescent probe for separate detection of endogenous biothiols and SO2 in living cells","volume":"6","author":"Wu","year":"2018","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.saa.2025.125753_b0065","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.snb.2018.01.139","article-title":"A new lipid droplets-targeted fluorescence probe for specific detection of SO2 derivatives in living cells","volume":"261","author":"Huang","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"10.1016\/j.saa.2025.125753_b0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2022.131962","article-title":"A reversible NIR fluorescent probe for monitoring of SO2 and formaldehyde in live cells and zebrafish","volume":"366","author":"Zhu","year":"2022","journal-title":"Sens. Actuators, B"},{"key":"10.1016\/j.saa.2025.125753_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2019.117788","article-title":"A novel ratiometric fluorescent probe for \u201cnaked-eye\u201d detection of sulfite ion: Applications in detection of biological SO32\u2212 ions in food and live cells","volume":"228","author":"Venkatachalam","year":"2020","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.125753_b0080","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.talanta.2017.08.054","article-title":"A novel colorimetric and ratiometric fluorescent probe for visualizing SO2 derivatives in environment and living cells","volume":"176","author":"Ye","year":"2018","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2025.125753_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2020.119128","article-title":"An efficient hemicyanine dyes-based ratiometric fluorescence probe for sulfur dioxide derivatives in live-cells and seawater","volume":"247","author":"Nie","year":"2021","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.125753_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.131563","article-title":"High-performance near-infrared fluorescence probe for fast and specific visualization of harmful sulfite in food, living cells, and zebrafish","volume":"427","author":"Jiang","year":"2022","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.saa.2025.125753_b0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2022.123699","article-title":"A dual-positive charges strategy for sensitive and quantitative detection of mitochondrial SO2 in cancer cells and tumor tissue","volume":"249","author":"Ye","year":"2022","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2025.125753_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2022.132959","article-title":"Rational construction of sulfur dioxide and viscosity bifunctional fluorescent probe and its applications in water, food and bioimaging","volume":"375","author":"Cui","year":"2023","journal-title":"Sens. Actuators, B"},{"key":"10.1016\/j.saa.2025.125753_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2023.341177","article-title":"Imaging and detection of sulfite in acute liver injury with a novel quinoxaline-based fluorescent probe","volume":"1261","author":"Hu","year":"2023","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.saa.2025.125753_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2023.111655","article-title":"Water-soluble fluorescent probe for specific detection of SO2 derivatives in food and cells","volume":"219","author":"Li","year":"2023","journal-title":"Dyes Pigm."},{"key":"10.1016\/j.saa.2025.125753_b0115","doi-asserted-by":"crossref","first-page":"4174","DOI":"10.1039\/D3AN01067H","article-title":"Probing fluctuations in sulfur dioxide and viscosity levels during mitochondrial dysfunction using a dual-response fluorescent probe with good water solubility","volume":"148","author":"Zhang","year":"2023","journal-title":"Analyst"},{"key":"10.1016\/j.saa.2025.125753_b0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2024.124463","article-title":"A triphenylamine-benzofuran-derived fluorescent probe for monitoring sulfite in Chinese medicinal materials and bioimaging","volume":"317","author":"Mao","year":"2024","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.125753_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.138183","article-title":"A practical chromogenic and fluorogenic dual-mode sensing platform for rapid quantification of sulfite in food","volume":"440","author":"Yue","year":"2024","journal-title":"Food Chem."},{"key":"10.1016\/j.saa.2025.125753_b0130","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.dyepig.2017.10.002","article-title":"Selective visualization of hypochlorite and its fluctuation in cancer cells by a mitochondria-targeting ratiometric fluorescent probe","volume":"149","author":"Hu","year":"2018","journal-title":"Dyes Pigm."},{"key":"10.1016\/j.saa.2025.125753_b0135","doi-asserted-by":"crossref","first-page":"11935","DOI":"10.1021\/jf2032928","article-title":"A boron-dipyrromethene-based fluorescent probe for colorimetric and ratiometric detection of sulfite","volume":"59","author":"Gu","year":"2011","journal-title":"J. Agric. Food. Chem."},{"key":"10.1016\/j.saa.2025.125753_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2022.120870","article-title":"A ratiometric fluorescent probe for selective detection of thiophenol derivatives","volume":"271","author":"Li","year":"2022","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.125753_b0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2022.111017","article-title":"A ratiometric lysosome-targeted fluorescent probe for imaging SO2 based on the coumarin-quinoline-julolidine molecular system","volume":"210","author":"Liu","year":"2023","journal-title":"Dyes Pigm."},{"key":"10.1016\/j.saa.2025.125753_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2020.108639","article-title":"A new FRET-based ratiometric fluorescent probe for the detection of SO2 derivatives in mitochondria of living cells","volume":"181","author":"Wang","year":"2020","journal-title":"Dyes Pigm."},{"key":"10.1016\/j.saa.2025.125753_b0155","doi-asserted-by":"crossref","first-page":"11263","DOI":"10.1039\/C9CC04411F","article-title":"Development of a unique reversible fluorescent probe for tracking endogenous sulfur dioxide and formaldehyde fluctuation in vivo","volume":"55","author":"Ma","year":"2019","journal-title":"Chem. Commun."},{"key":"10.1016\/j.saa.2025.125753_b0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2022.121519","article-title":"Simultaneous detection of lysosomal SO2 and viscosity using a hemicyanine-based fluorescent probe","volume":"280","author":"Li","year":"2022","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.125753_b0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2021.109180","article-title":"A novel endoplasmic reticulum-targeted ratiometric fluorescent probe based on FRET for the detection of SO2 derivatives","volume":"188","author":"Li","year":"2021","journal-title":"Dyes Pigm."},{"key":"10.1016\/j.saa.2025.125753_b0170","doi-asserted-by":"crossref","first-page":"15220","DOI":"10.1021\/acs.analchem.9b04103","article-title":"Rational design of a rigid fluorophore-molecular rotor-based probe for high signal-to-background ratio detection of sulfur dioxide in viscous system","volume":"91","author":"He","year":"2019","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2025.125753_b0175","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.snb.2018.12.158","article-title":"Mitochondria-targeted and FRET based ratiometric fluorescent probe for SO2 and its cell imaging","volume":"284","author":"Liu","year":"2019","journal-title":"Sens. Actuators, B"},{"key":"10.1016\/j.saa.2025.125753_b0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2020.108869","article-title":"FRET-dependent single\/two-channel switch endowing a dual detection for sulfite and its organelle targeting applications","volume":"184","author":"Huang","year":"2021","journal-title":"Dyes Pigm."},{"key":"10.1016\/j.saa.2025.125753_b0185","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1021\/ac503281z","article-title":"Selective, highly sensitive fluorescent probe for the detection of sulfur dioxide derivatives in aqueous and biological environments","volume":"87","author":"Chen","year":"2015","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2025.125753_b0190","doi-asserted-by":"crossref","first-page":"45294","DOI":"10.1038\/srep45294","article-title":"A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells","volume":"7","author":"Li","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.saa.2025.125753_b0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2020.108658","article-title":"A mitochondria-targeted ratiometric fluorescence probe for detection of SO2 derivatives in living cells","volume":"182","author":"Sun","year":"2020","journal-title":"Dyes Pigm."},{"key":"10.1016\/j.saa.2025.125753_b0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2023.124302","article-title":"FRET-based fluorescent probe with favorable water solubility for simultaneous detection of SO2 derivatives and viscosity","volume":"256","author":"Liu","year":"2023","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2025.125753_b0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2023.124529","article-title":"A review: Small organic molecule dual\/multi-organelle-targeted fluorescent probes","volume":"259","author":"Huang","year":"2023","journal-title":"Talanta"}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142525000599?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142525000599?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T01:04:21Z","timestamp":1761440661000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386142525000599"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":41,"alternative-id":["S1386142525000599"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2025.125753","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lysosomal-targeted fluorescent probe for detecting SO2 derivatives in human umbilical vein endothelial cells","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2025.125753","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"125753"}}