{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T12:09:11Z","timestamp":1792757351421,"version":"4.5.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.saa.2025.125909","type":"journal-article","created":{"date-parts":[[2025,2,16]],"date-time":"2025-02-16T18:18:52Z","timestamp":1739729932000},"page":"125909","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["A selective BODIPY-based fluorescent sensor for the detection of Cu2+ ions in biological and environmental samples"],"prefix":"10.1016","volume":"333","author":[{"given":"Asli","family":"Eldem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erman","family":"Kibris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammed","family":"Ucuncu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2025.125909_b0005","doi-asserted-by":"crossref","first-page":"6060","DOI":"10.3390\/molecules26196060","article-title":"Heavy metals and human health: possible exposure pathways and the competition for protein binding sites","volume":"26","author":"Witkowska","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.saa.2025.125909_b0010","doi-asserted-by":"crossref","unstructured":"M. Mohammad Ali, D. Hossain, Al-Imran, Md. Suzan Khan, M. Begum, M. Hasan Osman, Environmental pollution with heavy metals: a public health concern, in: Heavy Metals - Their Environmental Impacts and Mitigation, IntechOpen, 2021. doi: 10.5772\/intechopen.96805.","DOI":"10.5772\/intechopen.96805"},{"key":"10.1016\/j.saa.2025.125909_b0015","series-title":"Interrelations Between Essential Metal Ions and Human Diseases","author":"Sigel","year":"2013"},{"key":"10.1016\/j.saa.2025.125909_b0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.157170","article-title":"\u201cKilling two birds with one stone\u201d: A fluorescent hybrid nanoparticle modified with BODIPY for efficiently detection and removal of toxic Cu (II) ion from aqueous solutions","volume":"845","author":"Bilgic","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.saa.2025.125909_b0025","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2023.1209156","article-title":"Copper in cancer: from limiting nutrient to therapeutic target","volume":"13","author":"Tang","year":"2023","journal-title":"Front. Oncol."},{"key":"10.1016\/j.saa.2025.125909_b0030","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s13204-015-0452-4","article-title":"Detection of heavy metals (Cu+2, Hg+2) by biosynthesized silver nanoparticles","volume":"6","author":"Maiti","year":"2016","journal-title":"Appl. Nanosci."},{"key":"10.1016\/j.saa.2025.125909_b0035","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.3390\/molecules28052303","article-title":"Recent advances in cancer therapeutic copper-based nanomaterials for antitumor therapy","volume":"28","author":"Aishajiang","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.saa.2025.125909_b0040","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1007\/s10895-023-03455-1","article-title":"Synthesis and applications of fluorescent chemosensors: a review","volume":"34","author":"Khan","year":"2024","journal-title":"J. Fluoresc."},{"key":"10.1016\/j.saa.2025.125909_b0045","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.snb.2014.01.116","article-title":"A BODIPY-based \u201cturn-on\u201d fluorescent and colorimetric sensor for selective detection of Cu2+ in aqueous media and its application in cell imaging","volume":"196","author":"Zhang","year":"2014","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.saa.2025.125909_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2020.119330","article-title":"A novel fluorescent BODIPY-based probe for detection of Cu2+ and H2S based on displacement approach","volume":"249","author":"Wu","year":"2021","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2025.125909_b0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2020.129037","article-title":"A rhodamine based fluorescent chemodosimeter for the selective and sensitive detection of copper (II) ions in aqueous media and living cells","volume":"1224","author":"Karaku\u015f","year":"2021","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.saa.2025.125909_b0060","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.snb.2013.12.037","article-title":"A new rhodamine derivative-based chemosensor for highly selective and sensitive determination of Cu2+","volume":"193","author":"Puangploy","year":"2014","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.saa.2025.125909_b0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.jphotochem.2022.113841","article-title":"Highly sensitive and selective coumarin-based fluorescent chemosensor for Cu2+ detection","volume":"427","author":"Srisuwan","year":"2022","journal-title":"J. Photochem. Photobiol. A Chem."},{"key":"10.1016\/j.saa.2025.125909_b0070","doi-asserted-by":"crossref","first-page":"3857","DOI":"10.1039\/C9AY00463G","article-title":"A novel coumarin-based ligand: a turn-off and highly selective fluorescent chemosensor for Cu 2+ in water","volume":"11","author":"Ngororabanga","year":"2019","journal-title":"Anal. Methods"},{"key":"10.1016\/j.saa.2025.125909_b0075","doi-asserted-by":"crossref","first-page":"301","DOI":"10.3390\/bios13030301","article-title":"Development of a fluorescein-based probe with an \u201coff\u2013on\u201d mechanism for selective detection of copper (II) ions and its application in imaging of living cells","volume":"13","author":"Bai","year":"2023","journal-title":"Biosensors (Basel)"},{"key":"10.1016\/j.saa.2025.125909_b0080","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.932826","article-title":"A highly sensitive and selective fluorescein-based Cu2+ probe and its bioimaging in cell","volume":"9","author":"Leng","year":"2022","journal-title":"Front. Nutr."},{"key":"10.1016\/j.saa.2025.125909_b0085","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.tet.2016.12.016","article-title":"A sensitive fluorescent probe for cysteine and Cu2+ based on 1,8-naphthalimide derivatives and its application in living cells imaging","volume":"73","author":"Shen","year":"2017","journal-title":"Tetrahedron"},{"key":"10.1016\/j.saa.2025.125909_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.tet.2023.133652","article-title":"A novel naphthalimide-based fluorescent probe with sulfonyl hydrazide as receptor for detection of Cu2+","volume":"146","author":"Zhou","year":"2023","journal-title":"Tetrahedron"},{"key":"10.1016\/j.saa.2025.125909_b0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2019.117540","article-title":"A novel colorimetric and \u201cturn-off\u201d fluorescent probe based on catalyzed hydrolysis reaction for detection of Cu2+ in real water and in living cells","volume":"227","author":"Liu","year":"2020","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2025.125909_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.inoche.2021.109181","article-title":"Multi responsive chemosensor for the determination of metal ions (Co2+, Cu2+, and Zn2+ ions)","volume":"136","author":"Bhalla","year":"2022","journal-title":"Inorg. Chem. Commun."},{"key":"10.1016\/j.saa.2025.125909_b0105","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1007\/s10895-018-2263-y","article-title":"Review on recent advances in metal ions sensing using different fluorescent probes","volume":"28","author":"Chowdhury","year":"2018","journal-title":"J. Fluoresc."},{"key":"10.1016\/j.saa.2025.125909_b0110","doi-asserted-by":"crossref","DOI":"10.1002\/ejic.202200093","article-title":"A cyclopalladated BODIPY construct as a fluorescent probe for carbon monoxide","volume":"2022","author":"\u00c7evik Eren","year":"2022","journal-title":"Eur J. Inorg. Chem."},{"key":"10.1016\/j.saa.2025.125909_b0115","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.3390\/mi13081298","article-title":"Recent advances of optical sensors for copper ion detection","volume":"13","author":"Gerdan","year":"2022","journal-title":"Micromachines (Basel)"},{"key":"10.1016\/j.saa.2025.125909_b0120","doi-asserted-by":"crossref","first-page":"3885","DOI":"10.3390\/ijerph20053885","article-title":"Removal of copper ions from wastewater: a review","volume":"20","author":"Liu","year":"2023","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.saa.2025.125909_b0125","doi-asserted-by":"crossref","first-page":"17560","DOI":"10.1021\/ja1075663","article-title":"Bodipy dyes with tunable redox potentials and functional groups for further tethering: preparation, electrochemical, and spectroscopic characterization","volume":"132","author":"Krumova","year":"2010","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.saa.2025.125909_b0130","doi-asserted-by":"crossref","first-page":"5884","DOI":"10.1039\/C4CC01958J","article-title":"A BODIPY-based reactive probe for the detection of Au(<scp>iii<\/scp>) species and its application to cell imaging","volume":"50","author":"\u00dc\u00e7\u00fcnc\u00fc","year":"2014","journal-title":"Chem. Commun."},{"key":"10.1016\/j.saa.2025.125909_b0135","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3390\/chemosensors9070165","article-title":"BODIPY-pyridylhydrazone probe for fluorescence turn-on detection of Fe3+ and its bioimaging application","volume":"9","author":"Nootem","year":"2021","journal-title":"Chemosensors"},{"key":"10.1016\/j.saa.2025.125909_b0140","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1515\/znb-2007-0515","article-title":"Synthesis and spectral characterization of hydrazone schiff bases derived from 2,4-dinitrophenylhydrazine. Crystal structure of salicylaldehyde-2,4-dinitrophenylhydrazone","volume":"62","author":"Monfared","year":"2007","journal-title":"Zeitschrift F\u00fcr Naturforschung B"},{"key":"10.1016\/j.saa.2025.125909_b0145","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1039\/D2QM01351G","article-title":"Molecular design of dual-emission rhodamine analogs","volume":"7","author":"Wu","year":"2023","journal-title":"Mater. Chem. Front."},{"key":"10.1016\/j.saa.2025.125909_b0150","doi-asserted-by":"crossref","DOI":"10.3390\/molecules26196072","article-title":"A galactosidase-activatable fluorescent probe for detection of bacteria based on bodipy","volume":"26","author":"Chen","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.saa.2025.125909_b0155","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1039\/D1CS01097B","article-title":"Photoinduced electron transfer (PeT) based fluorescent probes for cellular imaging and disease therapy","volume":"52","author":"Niu","year":"2023","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.saa.2025.125909_b0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.molliq.2020.113145","article-title":"Exploring the simultaneous biothiols-differentiating detecting feature of a BODIPY chemosensor with DFT\/TDDFT","volume":"309","author":"Bai","year":"2020","journal-title":"J. Mol. Liq."}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138614252500215X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138614252500215X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:29:14Z","timestamp":1762543754000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S138614252500215X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":32,"alternative-id":["S138614252500215X"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2025.125909","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A selective BODIPY-based fluorescent sensor for the detection of Cu2+ ions in biological and environmental samples","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2025.125909","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"125909"}}