{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T11:01:46Z","timestamp":1792926106808,"version":"4.5.0"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22206154"],"award-info":[{"award-number":["22206154"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.saa.2025.126599","type":"journal-article","created":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T19:03:52Z","timestamp":1750705432000},"page":"126599","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["A large Stokes shift peptide-based fluorescent probe for Cd2+ and Hg2+ detection in aqueous solution and its applications in bioimaging, real sample, logic gate and smartphone device"],"prefix":"10.1016","volume":"343","author":[{"given":"Chunmei","family":"Pu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinlin","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2025.126599_bb0005","series-title":"Cadmium","author":"Friberg","year":"1992"},{"key":"10.1016\/j.saa.2025.126599_bb0010","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1016\/j.scitotenv.2018.12.096","article-title":"Cadmium pigments in consumer products and their health risks","volume":"657","author":"Turner","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.saa.2025.126599_bb0015","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1038\/40785","article-title":"Metallothionein in snail Cd and Cu metabolism","volume":"388","author":"Dallinger","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.saa.2025.126599_bb0020","doi-asserted-by":"crossref","first-page":"3210","DOI":"10.1039\/C1CS15245A","article-title":"Fluorescent and colorimetric sensors for detection of lead, cadmium, and mercury ions","volume":"41","author":"Kim","year":"2012","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.saa.2025.126599_bb0025","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1021\/ja0643319","article-title":"A selective fluorescent sensor for imaging Cd2+ in living cells","volume":"129","author":"Peng","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.saa.2025.126599_bb0030","article-title":"Fabrication of reusable probe impregnated polymer monolithic sensor for the visual detection of Cd2+ in natural waters and cigarette samples","volume":"459","author":"Sivaraman","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.saa.2025.126599_bb0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2023.122979","article-title":"A novel fluorescence probe for the recognition of Cd2+ and its application","volume":"301","author":"Huang","year":"2023","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.126599_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2023.109067","article-title":"A novel difunctional COF-loaded peptide au nanocluster probe and its application to molecular spectral determination of trace Cd2+","volume":"193","author":"Shu","year":"2023","journal-title":"Microchem. J."},{"key":"10.1016\/j.saa.2025.126599_bb0045","article-title":"A facile AIE fluorescent probe with large Stokes shift for the detection of Cd2+ in real water samples and living cells","volume":"243","author":"Jiang","year":"2022","journal-title":"JOL"},{"key":"10.1016\/j.saa.2025.126599_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.inoche.2022.110187","article-title":"Phenanthroline-based ligand scaffold as an efficient colorimetric and ratiometric fluorescence probe for Zn2+ and Cd2+ ion detection","volume":"146","author":"Tian","year":"2022","journal-title":"Inorg. Chem. Commun."},{"key":"10.1016\/j.saa.2025.126599_bb0055","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1080\/10937401003673750","article-title":"Transport of inorganic mercury and methylmercury in target tissues and organs","volume":"13","author":"Bridges","year":"2010","journal-title":"J. Toxicol. Environ. Health B Crit. Rev."},{"key":"10.1016\/j.saa.2025.126599_bb0060","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.etap.2005.03.007","article-title":"Low dose mercury toxicity and human health","volume":"20","author":"Zahir","year":"2005","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.saa.2025.126599_bb0065","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1007\/s11356-014-3544-x","article-title":"Health risk and significance of mercury in the environment","volume":"22","author":"Li","year":"2015","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.saa.2025.126599_bb0070","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1006\/enrs.1998.3832","article-title":"Mercury levels along the food chain and risk for exposed populations","volume":"77","author":"Renzoni","year":"1998","journal-title":"Environ. Res."},{"key":"10.1016\/j.saa.2025.126599_bb0075","doi-asserted-by":"crossref","first-page":"3443","DOI":"10.1021\/cr068000q","article-title":"Tools and tactics for the optical detection of mercuric ion","volume":"108","author":"Nolan","year":"2008","journal-title":"Chem. Rev."},{"key":"10.1016\/j.saa.2025.126599_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2025.113489","article-title":"Facile and sensitive Hg2+ fluorescent probe based on repurposed molecular glue (3-hydroxythalidomide) and bioimaging in HeLa cells","volume":"212","author":"Liu","year":"2025","journal-title":"Microchem. J."},{"key":"10.1016\/j.saa.2025.126599_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2025.141930","article-title":"Hg2+-induced hydrolysis of fluorescein hydrazone: a new fluorescence probe for selective recognition Hg2+ in an aqueous solution","volume":"1334","author":"Zavalishin","year":"2025","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.saa.2025.126599_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2025.137527","article-title":"Specific and low-level detection of Hg2+ and CN\u2212 in aqueous solution by a new fluorescent probe: its real sample applications including cell, soil, water, and food","volume":"433","author":"Oguz","year":"2025","journal-title":"Sens. Actuators B"},{"key":"10.1016\/j.saa.2025.126599_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2024.141030","article-title":"A highly specific flavonol-based fluorescent probe for simultaneous detection of Al3+ and Hg2+ and its applications in actual environmental soil samples and living cells","volume":"1325","author":"Wang","year":"2025","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.saa.2025.126599_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2024.125480","article-title":"Selenophene-containing silicon-rhodamine: a novel near-infrared fluorescent probe for Hg2+ detection and its application in cell imaging","volume":"328","author":"Wang","year":"2025","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.126599_bb0105","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1016\/j.snb.2011.12.023","article-title":"Selectively and sensitively monitoring Hg2+ in aqueous buffer solutions with fluorescent sensors based on unnatural amino acids","volume":"161","author":"Lohani","year":"2012","journal-title":"Sensor Actuat. B Chem."},{"key":"10.1016\/j.saa.2025.126599_bb0110","doi-asserted-by":"crossref","first-page":"3220","DOI":"10.1039\/b925744f","article-title":"A highly sensitive and selective detection of Hg(II) in 100% aqueous solution with fluorescent labeled dimerized Cys residues","volume":"8","author":"Joshi","year":"2010","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.saa.2025.126599_bb0115","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.bios.2017.02.001","article-title":"Tuning of the selectivity of fluorescent peptidyl bioprobe using aggregation induced emission for heavy metal ions by buffering agents in 100% aqueous solutions","volume":"92","author":"Neupane","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.saa.2025.126599_bb0120","doi-asserted-by":"crossref","first-page":"5007","DOI":"10.1016\/j.tetlet.2013.07.003","article-title":"Selective and sensitive turn on detection of Hg2+ in aqueous solution using a thioether-appended dipeptide","volume":"54","author":"Neupane","year":"2013","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.saa.2025.126599_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.133331","article-title":"A rapid and specific fluorescent probe based on aggregation-induced emission enhancement for mercury ion detection in living systems","volume":"465","author":"An","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.saa.2025.126599_bb0130","doi-asserted-by":"crossref","first-page":"15770","DOI":"10.1039\/C8NJ03624A","article-title":"A peptide-based multifunctional fluorescent probe for Cu2+, Hg2+ and biothiols","volume":"42","author":"Pang","year":"2018","journal-title":"New J. Chem."},{"key":"10.1016\/j.saa.2025.126599_bb0135","doi-asserted-by":"crossref","first-page":"4717","DOI":"10.1007\/s00216-022-04094-4","article-title":"A novel peptide-based fluorescent probe for highly selective detection of mercury (II) ions in real water samples and living cells based on aggregation-induced emission effect","volume":"414","author":"Wang","year":"2022","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.saa.2025.126599_bb0140","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.saa.2018.09.029","article-title":"A fluorescent dansyl-based peptide probe for highly selective and sensitive detect Cd2+ ions and its application in living cell imaging","volume":"207","author":"Wang","year":"2019","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.126599_bb0145","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.microc.2019.02.004","article-title":"A retrievable and highly selective peptide-based fluorescent probe for detection of Cd2+ and Cys in aqueous solutions and live cells","volume":"146","author":"Wang","year":"2019","journal-title":"Microchem. J."},{"key":"10.1016\/j.saa.2025.126599_bb0150","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.saa.2019.03.014","article-title":"A novel peptide-based fluorescent chemosensor for Cd(II) ions and its applications in bioimaging","volume":"216","author":"Wang","year":"2019","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.126599_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2023.123829","article-title":"A novel ratiometric peptide-based fluorescent probe for sequential detection of Hg2+ and S2\u2212 ions and its application in living cells and zebrafish imaging","volume":"309","author":"Zhou","year":"2024","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.126599_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2022.121836","article-title":"A novel peptide-based relay fluorescent probe with a large Stokes shift for detection of Hg2+ and S2\u2212 in 100% aqueous medium and living cells: visual detection via test strips and smartphone","volume":"285","author":"Wei","year":"2023","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.126599_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2024.124514","article-title":"A highly sensitive and selective fluorescent \u201con-off-on\u201d peptide-based probe for sequential detection of Hg2+ and S2\u2212 ions: applications in living cells and zebrafish imaging","volume":"318","author":"Zhou","year":"2024","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.126599_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2025.126032","article-title":"A novel dual-function peptide-based fluorescent probe with large Stokes shift for the simultaneous detection and quantification of Ag(I) and Hg(II) ions","volume":"336","author":"Pu","year":"2025","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.saa.2025.126599_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2024.140146","article-title":"Highly selective peptide-based fluorescent turn-on probe with large Stokes shift for the detection of cd(II) and its applications in bio-imaging and smartphone-assisted recognition","volume":"1321","author":"Deng","year":"2025","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.saa.2025.126599_bb0180","first-page":"518","article-title":"Positive curvature in Stern-Volmer plot described by a generalized model for static quenching","volume":"206","author":"Ciotta","year":"2019","journal-title":"JOL"},{"key":"10.1016\/j.saa.2025.126599_bb0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2020.119237","article-title":"Fluorescence emission quenching of RdB fluorophores in attendance of various blood type RBCs based on Stern-Volmer formalism","volume":"248","author":"Seyedi","year":"2021","journal-title":"Spectrochim. Acta, Part A"}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142525009060?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142525009060?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:34:11Z","timestamp":1762544051000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386142525009060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":37,"alternative-id":["S1386142525009060"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2025.126599","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A large Stokes shift peptide-based fluorescent probe for Cd2+ and Hg2+ detection in aqueous solution and its applications in bioimaging, real sample, logic gate and smartphone device","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2025.126599","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"126599"}}