{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T04:52:27Z","timestamp":1775019147973,"version":"3.50.1"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T00:00:00Z","timestamp":1754438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004569","name":"Ministerstwo Edukacji i Nauki","doi-asserted-by":"publisher","award":["N18\/DBS\/000018"],"award-info":[{"award-number":["N18\/DBS\/000018"]}],"id":[{"id":"10.13039\/501100004569","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.saa.2025.126782","type":"journal-article","created":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T23:57:10Z","timestamp":1754438230000},"page":"126782","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury"],"prefix":"10.1016","volume":"345","author":[{"given":"Kamil","family":"Kawon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuzanna","family":"Setkowicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuzanna","family":"Rauk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna","family":"Chwiej","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2025.126782_bb0005","first-page":"3","article-title":"Epidemiology of traumatic brain injury, traumatic brain injury: science, practice","author":"Iaccarino","year":"2021","journal-title":"Evid. Ethics"},{"key":"10.1016\/j.saa.2025.126782_bb0010","first-page":"1","article-title":"Current trends in biomarker discovery and analysis tools for traumatic brain injury","author":"Martinez","year":"2019","journal-title":"J. Biol. Eng."},{"key":"10.1016\/j.saa.2025.126782_bb0015","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1007\/s11910-012-0301-8","article-title":"Biomarkers in traumatic brain injury","volume":"12","author":"Sharma","year":"2012","journal-title":"Curr. Neurol. Neurosci. Rep."},{"key":"10.1016\/j.saa.2025.126782_bb0020","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1177\/1545968319899920","article-title":"Biomarkers in traumatic spinal cord injury\u2014technical and clinical considerations: a systematic review","volume":"34","author":"Leister","year":"2020","journal-title":"Neurorehabil. Neural Repair"},{"key":"10.1016\/j.saa.2025.126782_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.surg.2024.07.090","article-title":"Beyond Glasgow coma scale: prehospital prediction of traumatic brain injury","volume":"179","author":"Schucht","year":"2025","journal-title":"Surgery"},{"key":"10.1016\/j.saa.2025.126782_bb0030","series-title":"Predicting Injury Severity and Neurological Recovery after Acute Cervical Spinal Cord Injury: A Comparison of Cerebrospinal Fluid and Magnetic Resonance Imaging Biomarkers","first-page":"435","volume":"35","author":"Dalkilic","year":"2018"},{"key":"10.1016\/j.saa.2025.126782_bb0035","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1093\/brain\/awm216","article-title":"White matter integrity and cognition in chronic traumatic brain injury: a diffusion tensor imaging study","volume":"130","author":"Kraus","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.saa.2025.126782_bb0040","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1001\/archneur.63.3.418","article-title":"Cognitive sequelae of diffuse axonal injury","volume":"63","author":"Scheid","year":"2006","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.saa.2025.126782_bb0045","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1007\/s00221-021-06178-6","article-title":"Animal models of traumatic brain injury: a review of pathophysiology to biomarkers and treatments","volume":"239","author":"Petersen","year":"2021","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.saa.2025.126782_bb0050","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1750-1326-9-55","article-title":"Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury","volume":"9","author":"Namjoshi","year":"2014","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.saa.2025.126782_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2020.113409","article-title":"The closed-head impact model of engineered rotational acceleration (CHIMERA) as an application for traumatic brain injury pre-clinical research: a status report","volume":"333","author":"McNamara","year":"2020","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.saa.2025.126782_bb0060","doi-asserted-by":"crossref","first-page":"5332","DOI":"10.1007\/s12035-018-1454-5","article-title":"Animal models of traumatic brain injury and assessment of injury severity","author":"Ma","year":"2019","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.saa.2025.126782_bb0065","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/0736-5748(94)90027-2","article-title":"Age-dependent changes in the proliferative response of S-100 protein-positive glial cells to injury in the rat brain","volume":"12","author":"Janeczko","year":"1994","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.saa.2025.126782_bb0070","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/0006-8993(89)90566-0","article-title":"Spatiotemporal patterns of the astroglial proliferation in rat brain injured at the postmitotic stage of postnatal development: a combined immunocytochemical and autoradiographic study","volume":"485","author":"Janeczko","year":"1989","journal-title":"Brain Res."},{"key":"10.1016\/j.saa.2025.126782_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2021.120214","article-title":"The methods of vibrational microspectroscopy reveals long-term biochemical anomalies within the region of mechanical injury within the rat brain","volume":"263","author":"Kawon","year":"2021","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2025.126782_bb0080","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/S0920-1211(03)00029-9","article-title":"Long-term changes in susceptibility to pilocarpine-induced status epilepticus following neocortical injuries in the rat at different developmental stages","volume":"53","author":"Setkowicz","year":"2003","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.saa.2025.126782_bb0085","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.brainres.2016.03.008","article-title":"Physical training decreases susceptibility to pilocarpine-induced seizures in the injured rat brain","volume":"1642","author":"Setkowicz","year":"2016","journal-title":"Brain Res."},{"key":"10.1016\/j.saa.2025.126782_bb0090","doi-asserted-by":"crossref","first-page":"973","DOI":"10.4103\/NRR.NRR-D-23-02091","article-title":"Astrocytes, reactive astrogliosis, and glial scar formation in traumatic brain injury","volume":"20","author":"Cieri","year":"2025","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.saa.2025.126782_bb0095","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1007\/s12031-019-01417-6","article-title":"Glial scar\u2014a promising target for improving outcomes after CNS injury","volume":"70","author":"He","year":"2020","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.saa.2025.126782_bb0100","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1111\/fcp.12656","article-title":"Neuropharmacology in traumatic brain injury: from preclinical to clinical neuroprotection?","volume":"35","author":"Lerouet","year":"2021","journal-title":"Fundam. Clin. Pharmacol."},{"key":"10.1016\/j.saa.2025.126782_bb0105","doi-asserted-by":"crossref","first-page":"297","DOI":"10.3390\/antiox9040297","article-title":"Management of traumatic brain injury: from present to future","volume":"9","author":"Crupi","year":"2020","journal-title":"Antioxidants"},{"key":"10.1016\/j.saa.2025.126782_bb0110","doi-asserted-by":"crossref","first-page":"389","DOI":"10.3390\/biomedicines8100389","article-title":"Revisiting traumatic brain injury: from molecular mechanisms to therapeutic interventions","volume":"8","author":"Jarrahi","year":"2020","journal-title":"Biomedicines"},{"key":"10.1016\/j.saa.2025.126782_bb0115","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2019.00007","article-title":"The importance of therapeutic time window in the treatment of traumatic brain injury","volume":"13","author":"Mohamadpour","year":"2019","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.saa.2025.126782_bb0120","author":"Sullivan"},{"key":"10.1016\/j.saa.2025.126782_bb0125","doi-asserted-by":"crossref","first-page":"3063","DOI":"10.1089\/neu.2018.6171","article-title":"Sex differences in traumatic brain injury: what we know and what we should know","volume":"36","author":"Gupte","year":"2019","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.saa.2025.126782_bb0130","doi-asserted-by":"crossref","DOI":"10.1177\/1179069519844020","article-title":"Sex differences in animal models of traumatic brain injury","volume":"13","author":"Rubin","year":"2019","journal-title":"J. Exp. Neurosci."},{"key":"10.1016\/j.saa.2025.126782_bb0135","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1038\/s41582-018-0091-y","article-title":"Traumatic brain injury: sex, gender and intersecting vulnerabilities","volume":"14","author":"Mollayeva","year":"2018","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.saa.2025.126782_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.vibspec.2024.103671","article-title":"Spectralomics \u2013 towards a holistic adaptation of label free spectroscopy","volume":"132","author":"Byrne","year":"2024","journal-title":"Vib. Spectrosc."},{"issue":"2","key":"10.1016\/j.saa.2025.126782_bb0145","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s12551-023-01158-2","article-title":"Vibrational spectroscopy and multiphoton microscopy for label-free visualization of nervous system degeneration and regeneration","volume":"16","author":"Galli","year":"2023","journal-title":"Biophys. Rev."},{"key":"10.1016\/j.saa.2025.126782_bb0150","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1039\/C6AN02238C","article-title":"Label-free monitoring of tissue biochemistry following traumatic brain injury using Raman spectroscopy","volume":"142","author":"Surmacki","year":"2016","journal-title":"Analyst"},{"key":"10.1016\/j.saa.2025.126782_bb0155","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.3390\/cells12222589","article-title":"Raman spectroscopy spectral fingerprints of biomarkers of traumatic brain injury","volume":"12","author":"Harris","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.saa.2025.126782_bb0160","series-title":"Infrared Spectroscopy: Fundamentals and Applications","author":"Stuart","year":"2004"},{"key":"10.1016\/j.saa.2025.126782_bb0165","series-title":"Modern Raman Spectroscopy: A Practical Approach","author":"Smith","year":"2004"},{"issue":"1","key":"10.1016\/j.saa.2025.126782_bb0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-024-80590-0","article-title":"Multimodal separation and cross fusion network based on Raman spectroscopy and FTIR spectroscopy for diagnosis of thyroid malignant tumor metastasis","volume":"14","author":"Song","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.saa.2025.126782_bb0175","doi-asserted-by":"crossref","first-page":"918","DOI":"10.3390\/brainsci11070918","article-title":"Fourier transform infrared imaging\u2014a novel approach to monitor bio molecular changes in subacute mild traumatic brain injury","volume":"11","author":"Rakib","year":"2021","journal-title":"Brain Sci."},{"issue":"1","key":"10.1016\/j.saa.2025.126782_bb0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-021-92015-3","article-title":"Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury","volume":"11","author":"Ustaoglu","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.saa.2025.126782_bb0185","doi-asserted-by":"crossref","first-page":"2775","DOI":"10.1021\/acschemneuro.3c00331","article-title":"Does ketogenic diet used in pregnancy affect the nervous system development in offspring?FTIR microspectroscopy study","volume":"14","author":"Rugiel","year":"2023","journal-title":"ACS Chem. Nerosci."},{"key":"10.1016\/j.saa.2025.126782_bb0190","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1021\/acschemneuro.8b00471","article-title":"Biochemical changes indicate developmental stage in the hippocampal formation","volume":"10","author":"Chwiej","year":"2019","journal-title":"ACS Chem. Nerosci."},{"key":"10.1016\/j.saa.2025.126782_bb0195","doi-asserted-by":"crossref","first-page":"119189","DOI":"10.1016\/j.saa.2020.119189","article-title":"Biomolecular alterations in acute traumatic brain injury (TBI) using Fourier transform infrared (FTIR) imaging spectroscopy","volume":"248","author":"Rakib","year":"2021","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2025.126782_bb0200","doi-asserted-by":"crossref","unstructured":"S. Saladrigas-Manj\u00f3n, T. Du\u010di\u0107, L. Galindo, C. Fern\u00e1ndez-Avil\u00e9s, V. P\u00e9rez, R. de la Torre, P. Robledo, Effects of Cannabis Use on the Protein and Lipid Profile of Olfactory Neuroepithelium Cells from Schizophrenia Patients Studied by Synchrotron-Based FTIR Spectroscopy, Biomolecules 2020, Vol. 10, Page 329 10 (2020) 329. doi:https:\/\/doi.org\/10.3390\/BIOM10020329.","DOI":"10.3390\/biom10020329"},{"key":"10.1016\/j.saa.2025.126782_bb0205","doi-asserted-by":"crossref","first-page":"160","DOI":"10.52635\/eamr\/12.2.160-166","article-title":"Raman spectroscopy study of healthy and cancerous human breast tissue for cancer detection","volume":"12","author":"Jain","year":"2022","journal-title":"Explor. Anim. Med. Res."},{"key":"10.1016\/j.saa.2025.126782_bb0210","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1002\/jrs.4335","article-title":"Raman spectroscopy of proteins: a review","volume":"44","author":"Rygula","year":"2013","journal-title":"J. Raman Spectrosc."},{"key":"10.1016\/j.saa.2025.126782_bb0215","doi-asserted-by":"crossref","unstructured":"N.A. Brazhe, A.B. Evlyukhin, E.A. Goodilin, A.A. Semenova, S.M. Novikov, S.I. Bozhevolnyi, B.N. Chichkov, A.S. Sarycheva, A.A. Baizhumanov, E.I. Nikelshparg, L.I. Deev, E.G. Maksimov, G. V. Maksimov, O. Sosnovtseva, Probing cytochrome c in living mitochondria with surface-enhanced Raman spectroscopy, Scientific Reports 2015 5:1 5 (2015) 1\u201313. doi:https:\/\/doi.org\/10.1038\/srep13793.","DOI":"10.1038\/srep13793"},{"key":"10.1016\/j.saa.2025.126782_bb0220","first-page":"165972","article-title":"Age\u2013related and atherosclerosis\u2013related erythropathy in ApoE\/LDLR\u2212\/\u2212 mice","volume":"2020","author":"Dybas","year":"1866","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.saa.2025.126782_bb0225","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1007\/s00214-011-0925-9","article-title":"High-wavenumber FT-Raman spectroscopy for in vivo and ex vivo measurements of breast cancer","volume":"130","author":"Garc\u00eda-Flores","year":"2011","journal-title":"Theor. Chem. Accounts"},{"key":"10.1016\/j.saa.2025.126782_bb0230","first-page":"1307","article-title":"The pathophysiology of traumatic brain injury at a glance","volume":"6","author":"Prins","year":"2013","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.saa.2025.126782_bb0235","series-title":"Traumatic Brain Injury: Mechanistic Insight on Pathophysiology and Potential Therapeutic Targets, Journal of Molecular Neuroscience 2021 71:9 71 (2021)","author":"Thapa","year":"1725"},{"key":"10.1016\/j.saa.2025.126782_bb0240","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2019.00528","article-title":"Traumatic brain injuries: pathophysiology and potential therapeutic targets","volume":"13","author":"Ng","year":"2019","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.saa.2025.126782_bb0245","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.3390\/biology12081139","article-title":"Cellular and molecular pathophysiology of traumatic brain injury: what have we learned so far?","volume":"12","author":"Freire","year":"2023","journal-title":"Biology"},{"key":"10.1016\/j.saa.2025.126782_bb0250","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1042\/bse0590043","article-title":"Biological membranes","volume":"59","author":"Watson","year":"2015","journal-title":"Essays Biochem."},{"issue":"52","key":"10.1016\/j.saa.2025.126782_bb0255","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s10863-020-09846-4","article-title":"Lipid composition of the cancer cell membrane","volume":"5","author":"Szlasa","year":"2020","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1016\/j.saa.2025.126782_bb0260","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.semcdb.2020.08.004","article-title":"Lipid profiling of brain tissue and blood after traumatic brain injury: a review of human and experimental studies","volume":"112","author":"Nessel","year":"2021","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.saa.2025.126782_bb0265","doi-asserted-by":"crossref","DOI":"10.1152\/ajpcell.00024.2014","article-title":"Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue","volume":"307","author":"Colas","year":"2014","journal-title":"Am. J. Physiol. Cell Physiol."},{"issue":"8","key":"10.1016\/j.saa.2025.126782_bb0270","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1038\/nri3859","article-title":"Eicosanoid storm in infection and inflammation","volume":"15","author":"Dennis","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.saa.2025.126782_bb0275","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.13275","article-title":"The PI3K\/AKT signalling pathway in inflammation, cell death and glial scar formation after traumatic spinal cord injury: mechanisms and therapeutic opportunities","volume":"55","author":"He","year":"2022","journal-title":"Cell Prolif."},{"key":"10.1016\/j.saa.2025.126782_bb0280","doi-asserted-by":"crossref","first-page":"13467","DOI":"10.1523\/JNEUROSCI.2287-08.2008","article-title":"Matrix Metalloproteinase-9 facilitates glial scar formation in the injured spinal cord","volume":"28","author":"Hsu","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.saa.2025.126782_bb0285","doi-asserted-by":"crossref","first-page":"3112","DOI":"10.1096\/fj.201801670R","article-title":"Structural deciphering of the NG2\/CSPG4 proteoglycan multifunctionality","volume":"33","author":"Tamburini","year":"2019","journal-title":"FASEB J."},{"key":"10.1016\/j.saa.2025.126782_bb0290","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.conb.2006.09.004","article-title":"The role of extracellular matrix in CNS regeneration","volume":"17","author":"Busch","year":"2007","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.saa.2025.126782_bb0295","doi-asserted-by":"crossref","DOI":"10.1002\/wnan.1962","article-title":"Exploring the properties and potential of the neural extracellular matrix for next-generation regenerative therapies","volume":"16","author":"Ortega","year":"2024","journal-title":"Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol."},{"key":"10.1016\/j.saa.2025.126782_bb0300","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.autrev.2011.05.019","article-title":"Chondroitin sulphate proteoglycans: extracellular matrix proteins that regulate immunity of the central nervous system","volume":"10","author":"Haylock-Jacobs","year":"2011","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.saa.2025.126782_bb0305","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainresrev.2006.09.006","article-title":"The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system","volume":"54","author":"Galtrey","year":"2007","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.saa.2025.126782_bb0310","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/jnr.10523","article-title":"Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissue","volume":"71","author":"Tang","year":"2003","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.saa.2025.126782_bb0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.jchemneu.2023.102286","article-title":"Astrogliosis and associated CSPG upregulation adversely affect dendritogenesis, spinogenesis and synaptic activity in the cerebellum of a double-hit rat model of protein malnutrition (PMN) and lipopolysaccharide (LPS) induced bacterial infection","volume":"131","author":"John","year":"2023","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.saa.2025.126782_bb0320","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1021\/acschemneuro.0c00004","article-title":"Targeting chondroitin sulfate proteoglycans: an emerging therapeutic strategy to treat CNS injury","volume":"11","author":"Mukherjee","year":"2020","journal-title":"ACS Chem. Nerosci."},{"issue":"5","key":"10.1016\/j.saa.2025.126782_bb0325","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/nrn2808","article-title":"Traumatic brain injury and amyloid-\u03b2 pathology: a link to Alzheimer\u2019s disease?","volume":"11","author":"Johnson","year":"2010","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.saa.2025.126782_bb0330","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.biopsych.2021.05.025","article-title":"Traumatic brain injury and risk of neurodegenerative disorder","volume":"91","author":"Brett","year":"2022","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.saa.2025.126782_bb0335","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1111\/1556-4029.12743","article-title":"Characterization of protein alterations in damaged axons in the brainstem following traumatic brain injury using Fourier transform infrared microspectroscopy: a preliminary study","volume":"60","author":"Zhang","year":"2015","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.saa.2025.126782_bb0340","first-page":"1","article-title":"Characterization of the degradation of sheepskin by monitoring cytochrome c of Bacteria by Raman spectroscopy","author":"Mehta","year":"2021","journal-title":"Anal. Lett."},{"key":"10.1016\/j.saa.2025.126782_bb0345","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1080\/05704928.2014.923902","article-title":"Raman spectroscopy of biological tissues","volume":"50","author":"Talari","year":"2015","journal-title":"Appl. Spectrosc. Rev."},{"key":"10.1016\/j.saa.2025.126782_bb0350","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s00775-010-0724-0","article-title":"X-ray fluorescence analysis of long-term changes in the levels and distributions of trace elements in the rat brain following mechanical injury","volume":"16","author":"Chwiej","year":"2011","journal-title":"J. Biol. Inorg. Chem."},{"key":"10.1016\/j.saa.2025.126782_bb0355","doi-asserted-by":"crossref","first-page":"301","DOI":"10.3171\/jns.1994.80.2.0301","article-title":"A new model of diffuse brain injury in rats: part II: morphological characterization","volume":"80","author":"Abd-Elfattah Foda","year":"1994","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.saa.2025.126782_bb0360","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.bbagen.2010.01.006","article-title":"Influence of different estrogens on neuroplasticity and cognition in the hippocampus","volume":"1800","author":"Barha","year":"2010","journal-title":"Biochim. Biophys. Acta Gen. Subj."},{"key":"10.1016\/j.saa.2025.126782_bb0365","doi-asserted-by":"crossref","first-page":"11641","DOI":"10.1523\/JNEUROSCI.23-37-11641.2003","article-title":"Hippocampal excitability increases during the estrous cycle in the rat: a potential role for brain-derived neurotrophic factor","volume":"23","author":"Scharfman","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.saa.2025.126782_bb0370","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1046\/j.0953-816x.2001.01825.x","article-title":"Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus","volume":"14","author":"Berchtold","year":"2001","journal-title":"Eur. J. Neurosci."}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142525010893?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142525010893?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:34:13Z","timestamp":1762544053000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386142525010893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":74,"alternative-id":["S1386142525010893"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2025.126782","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2025.126782","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"126782"}}