{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T04:42:11Z","timestamp":1793940131634,"version":"4.8.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022A1515110842"],"award-info":[{"award-number":["2022A1515110842"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22504023"],"award-info":[{"award-number":["22504023"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008326","name":"Guangdong University of Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008326","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.saa.2025.126999","type":"journal-article","created":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T21:33:45Z","timestamp":1759008825000},"page":"126999","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["A ratiometric fluorescent probe with a large emission shift for the detection of sulfur dioxide derivatives in live cells, foods and plant"],"prefix":"10.1016","volume":"347","author":[{"given":"Junjie","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haijian","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yichao","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongmei","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonggang","family":"Min","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2025.126999_bb0005","doi-asserted-by":"crossref","first-page":"5134","DOI":"10.1038\/s41467-025-60449-2","article-title":"High resolution assessment of air quality and health in Europe under different climate mitigation scenarios","volume":"16","author":"Pisoni","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.saa.2025.126999_bb0010","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1038\/d41586-025-00053-y","article-title":"Air pollution and brain damage: what the science says","volume":"637","author":"Drew","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.saa.2025.126999_bb0015","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abq6830","article-title":"Daytime SO2 chemistry on ubiquitous urban surfaces as a source of organic sulfur compounds in ambient air","volume":"8","author":"Deng","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.saa.2025.126999_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2022.132685","article-title":"Effects of sulfite treatment on the quality of black fungus","volume":"385","author":"Ren","year":"2022","journal-title":"Food Chem."},{"key":"10.1016\/j.saa.2025.126999_bb0025","doi-asserted-by":"crossref","first-page":"10899","DOI":"10.1021\/acs.jafc.2c04571","article-title":"Novel colorimetric and NIR fluorescent probe for bisulfite\/sulfite detection in food and water samples and living cells based on the PET mechanism","volume":"70","author":"Li","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.saa.2025.126999_bb0030","doi-asserted-by":"crossref","first-page":"2701","DOI":"10.1111\/1541-4337.12607","article-title":"Sulfites in meat: occurrence, activity, toxicity, regulation, and detection. A comprehensive review","volume":"19","author":"D\u2019Amore","year":"2020","journal-title":"Compr. Rev. Food Sci. F."},{"key":"10.1016\/j.saa.2025.126999_bb0035","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s12038-025-00508-4","article-title":"Human adipose-derived stem cell exosomes alleviate human respiratory system-related cells damaged by exposure to SO2 derivatives","volume":"50","author":"Lee","year":"2025","journal-title":"J. Biosci."},{"key":"10.1016\/j.saa.2025.126999_bb0040","doi-asserted-by":"crossref","first-page":"14514","DOI":"10.1021\/acs.analchem.8b04355","article-title":"Visualizing endogenous sulfur dioxide derivatives in febrile-seizure-induced hippocampal damage by a two-photon energy transfer cassette","volume":"90","author":"Yang","year":"2018","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2025.126999_bb0045","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1089\/ars.2021.0213","article-title":"Sulfur dioxide: endogenous generation, biological effects, detection, and therapeutic potential","volume":"36","author":"Huang","year":"2022","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.saa.2025.126999_bb0050","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.ecoenv.2019.06.029","article-title":"SO2 derivatives and as co-exposure promote liver cancer metastasis through integrin \u03b1v\u03b23 activation","volume":"181","author":"Ji","year":"2019","journal-title":"Ecotox Environ Safe"},{"key":"10.1016\/j.saa.2025.126999_bb0055","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/s13580-017-0053-0","article-title":"The relationship between SO2 exposure and plant physiology: a mini review","volume":"58","author":"Lee","year":"2017","journal-title":"Hortic. Environ. Biotechnol."},{"key":"10.1016\/j.saa.2025.126999_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodcont.2021.108500","article-title":"Determination of sulfur dioxide in food by liquid chromatography with pre-column derivatization","volume":"132","author":"Mu","year":"2022","journal-title":"Food Control"},{"key":"10.1016\/j.saa.2025.126999_bb0065","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.jelechem.2018.03.020","article-title":"Electrochemical properties of a 2D-molybdenum disulfide\u2013modified electrode and its application in SO2 detection","volume":"815","author":"Xu","year":"2018","journal-title":"J. Electroanal. Chem."},{"key":"10.1016\/j.saa.2025.126999_bb0070","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1021\/ie0715198","article-title":"Simultaneous determination of SO3(g) and SO2(g) in a flowing gas","volume":"47","author":"Ibanez","year":"2008","journal-title":"Ind. Eng. Chem. Res."},{"key":"10.1016\/j.saa.2025.126999_bb0075","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1016\/j.foodres.2022.111780","article-title":"Simultaneous extraction\/derivatization for the analysis of sulfite by capillary electrophoresis: a high-throughput reference method to meet the demand of seafood inspection","volume":"161","author":"Goncalves","year":"2022","journal-title":"Food Res. Int."},{"key":"10.1016\/j.saa.2025.126999_bb0080","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1021\/acs.analchem.4c03540","article-title":"Zero-crosstalk tumor-targeting ratiometric near-infrared \u03b3-glutamyltranspeptidase probe for fluorescent-guided surgical resection of orthotopic hepatic tumor","volume":"97","author":"Yang","year":"2025","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2025.126999_bb0085","doi-asserted-by":"crossref","first-page":"18852","DOI":"10.1021\/acs.analchem.4c04529","article-title":"A novel colon-targeting ratiometric probe with large emission shift for imaging peroxynitrite in ulcerative colitis","volume":"96","author":"Zhang","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2025.126999_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2025.127668","article-title":"Rational construction of a self-assembled nanoprobe for specific imaging ATP in cancer cells","volume":"287","author":"Ai","year":"2025","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2025.126999_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2023.134421","article-title":"Dual-locking fluorescent nanoprobes for HAase-triggered carbon monoxide imaging in living cells","volume":"394","author":"Tian","year":"2023","journal-title":"Sensor Actuat B-Chem"},{"key":"10.1016\/j.saa.2025.126999_bb0100","article-title":"Unnatural triggers converted from tetrazine-attached sialic acid for activation of optoacoustic imaging-guided cancer theranostics","volume":"137","author":"Wu","year":"2025","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.saa.2025.126999_bb0105","article-title":"Structurally modulated formation of cyanine J-aggregates with sharp and tunable spectra for multiplexed optoacoustic and fluorescence bioimaging","volume":"63","author":"Zhang","year":"2024","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.saa.2025.126999_bb0110","doi-asserted-by":"crossref","first-page":"6101","DOI":"10.1021\/acs.analchem.4c06695","article-title":"AIE and ICT synergistic lysosome-targeted ratiometric fluorescence sensor for the detection and imaging of Th4+ in the liver of zebrafish and mice","volume":"97","author":"Hu","year":"2025","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2025.126999_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.136181","article-title":"Lysosome-targeted flavonoid ESIPT sensor for the selective sensing of UO22+ in pure water solutions and cell imaging","volume":"417","author":"Hu","year":"2024","journal-title":"Sensor Actuat B-Chem"},{"key":"10.1016\/j.saa.2025.126999_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2024.125613","article-title":"A highly-sensitive fluorescent probe for the detection of copper ions and its applications in water quality monitoring, neural cell imaging and plant imaging","volume":"329","author":"Chen","year":"2025","journal-title":"Spectrochim. Acta A"},{"key":"10.1016\/j.saa.2025.126999_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2025.216607","article-title":"Biomedical applications of fluorescent probes for detecting ischemia-reperfusion injury in different organs","volume":"534","author":"Jing","year":"2025","journal-title":"Coord. Chem. Rev."},{"key":"10.1016\/j.saa.2025.126999_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2022.214438","article-title":"Biomarker-activatable probes based on smart AIEgens for fluorescence and optoacoustic imaging","volume":"458","author":"Ouyang","year":"2022","journal-title":"Coord. Chem. Rev."},{"key":"10.1016\/j.saa.2025.126999_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2023.111129","article-title":"A novel colorimetric and red-emitting fluorescent probe based on benzopyrylium derivatives for selective detection and imaging of SO2 erivatives in cells and zebrafish","volume":"212","author":"Wang","year":"2023","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.saa.2025.126999_bb0140","doi-asserted-by":"crossref","first-page":"4144","DOI":"10.1021\/acs.analchem.4c06499","article-title":"Computational chemistry-assisted design of a dual-function fluorescent probe for viscosity sensing in liver damage and SO2 detection in vitro","volume":"97","author":"Liu","year":"2025","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2025.126999_bb0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.134003","article-title":"A novel fluorescence probe for ultrafast detection of SO2 derivatives\/biogenic amines and its multi-application: detecting food and fish freshness, fluorescent dye and bioimaging","volume":"469","author":"Yang","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.saa.2025.126999_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2025.137276","article-title":"A two-step recognition fluorescent probe for ultra-wide range detection of SO2 in food and water samples","volume":"429","author":"Lou","year":"2025","journal-title":"Sensor Actuat B-Chem"},{"key":"10.1016\/j.saa.2025.126999_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.138151","article-title":"Rational design of a rapidly responsive and highly selective fluorescent probe for SO2 derivatives detection and imaging","volume":"439","author":"Zhang","year":"2024","journal-title":"Food Chem."},{"key":"10.1016\/j.saa.2025.126999_bb0160","doi-asserted-by":"crossref","first-page":"4903","DOI":"10.1021\/acs.jafc.1c00797","article-title":"Ultrafast detection of sulfur dioxide derivatives by a distinctive \u201cdual-positive-ion\u201d platform that features a doubly activated but irreversible michael addition site","volume":"69","author":"Bao","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.saa.2025.126999_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2025.112958","article-title":"A novel fluorescent probe visualization and identification of sulfite in acute liver injury and knee osteoarthritis","volume":"242","author":"Chen","year":"2025","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.saa.2025.126999_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.133468","article-title":"A near-infrared endoplasmic reticulum-targeted fluorescent probe to visualize the fluctuation of SO2 during endoplasmic reticulum stress","volume":"431","author":"Yue","year":"2022","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.saa.2025.126999_bb0175","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.dyepig.2017.07.021","article-title":"A rapid-responsive fluorescent probe based on coumarin for selective sensing of sulfite in aqueous solution and its bioimaging by turn-on fluorescence signal","volume":"147","author":"Wang","year":"2017","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.saa.2025.126999_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.134685","article-title":"Sulfur dioxide-triggered visualization tool for auxiliary diagnosis of alcohol-induced \u201canti-inflammatory and pro-inflammatory\u201d development process","volume":"473","author":"Li","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.saa.2025.126999_bb0185","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1039\/C9CS00243J","article-title":"Synthetic ratiometric fluorescent probes for detection of ions","volume":"49","author":"Park","year":"2020","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.saa.2025.126999_bb0190","doi-asserted-by":"crossref","first-page":"5842","DOI":"10.1039\/D3SC01036H","article-title":"Organelle-targeting ratiometric fluorescent probes: design principles, detection mechanisms, bio-applications, and challenges","volume":"14","author":"Goshisht","year":"2023","journal-title":"Chem. Sci."},{"key":"10.1016\/j.saa.2025.126999_bb0195","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1007\/s12274-022-4840-2","article-title":"Design and applications of carbon dots-based ratiometric fluorescent probes: a review","volume":"16","author":"Chen","year":"2023","journal-title":"Nano Res"},{"key":"10.1016\/j.saa.2025.126999_bb0200","doi-asserted-by":"crossref","first-page":"4438","DOI":"10.2903\/j.efsa.2016.4433","volume":"14","author":"EFSA Panel on Food Additives and Nutrient Sources","year":"2016","journal-title":"EFSA J."},{"key":"10.1016\/j.saa.2025.126999_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2025.112767","article-title":"A quinolinium-based colorimetric and NIR fluorescent dual-channel sensing platform for specific detection of bisulfite in food, traditional Chinese medicine and living cells","volume":"239","author":"Chen","year":"2025","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.saa.2025.126999_bb0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.135369","article-title":"Near-infrared and multifunctional fluorescent probe enabled by cyanopyridine cyanine dye for bisulfite recognition and biological imaging","volume":"477","author":"Gu","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.saa.2025.126999_bb0215","doi-asserted-by":"crossref","first-page":"8741","DOI":"10.1080\/10408398.2023.2203737","article-title":"Novel insight into the role of sulfur dioxide in fruits and vegetables: chemical interactions, biological activity, metabolism, applications, and safety","volume":"24","author":"Li","year":"2024","journal-title":"Crit Rev Food Sci"},{"key":"10.1016\/j.saa.2025.126999_bb0220","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1111\/j.1365-3040.2011.02420.x","article-title":"Sulfite oxidase controls sulfur metabolism under SO2 exposure in Arabidopsis thaliana","volume":"35","author":"Randewig","year":"2024","journal-title":"Plant Cell Environ."}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138614252501306X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138614252501306X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T20:04:09Z","timestamp":1763064249000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S138614252501306X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":44,"alternative-id":["S138614252501306X"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2025.126999","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A ratiometric fluorescent probe with a large emission shift for the detection of sulfur dioxide derivatives in live cells, foods and plant","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2025.126999","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"126999"}}