{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T03:30:52Z","timestamp":1787801452122,"version":"build-2784847793"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515013081"],"award-info":[{"award-number":["2024A1515013081"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22008042"],"award-info":[{"award-number":["22008042"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U23A20453"],"award-info":[{"award-number":["U23A20453"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013804","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013804","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["YD9110002019"],"award-info":[{"award-number":["YD9110002019"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.saa.2025.127213","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T09:40:22Z","timestamp":1763631622000},"page":"127213","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"P2","title":["Construction of dual-rotor-BODIPY-based fluorescent probes with improved sensitivity and brightness for lipid-droplet viscosity imaging"],"prefix":"10.1016","volume":"348","author":[{"given":"Ting","family":"Fan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zixiang","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Jing","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jicheng","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianfu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.saa.2025.127213_bb0005","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/s41580-018-0085-z","article-title":"Dynamics and functions of lipid droplets","volume":"20","author":"Olzmann","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"10","key":"10.1016\/j.saa.2025.127213_bb0010","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1039\/D1CC05717K","article-title":"Recent advances in fluorescent probes for lipid droplets","volume":"58","author":"Zhao","year":"2022","journal-title":"Chem. Commun."},{"key":"10.1016\/j.saa.2025.127213_bb0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2024.216181","article-title":"Versatile organic fluorescent probes for visualizing the dynamics of lipid droplets","volume":"522","author":"Cao","year":"2025","journal-title":"Coordin. Chem. Rev."},{"issue":"40","key":"10.1016\/j.saa.2025.127213_bb0020","doi-asserted-by":"crossref","first-page":"10149","DOI":"10.1039\/D4TB01741B","article-title":"Recent advances in fluorescent probes for fatty liver imaging by detecting lipid droplets","volume":"12","author":"He","year":"2024","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.saa.2025.127213_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2023.124529","article-title":"A review: small organic molecule dual\/multi-organelle-targeted fluorescent probes","volume":"259","author":"Huang","year":"2023","journal-title":"Talanta"},{"issue":"21","key":"10.1016\/j.saa.2025.127213_bb0030","doi-asserted-by":"crossref","first-page":"12098","DOI":"10.1039\/D1CS00645B","article-title":"Small molecule based fluorescent chemosensors for imaging the microenvironment within specific cellular regions","volume":"50","author":"Yin","year":"2021","journal-title":"Chem. Soc. Rev."},{"issue":"3","key":"10.1016\/j.saa.2025.127213_bb0035","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1021\/acs.accounts.2c00643","article-title":"Fluorescent probes for biological species and microenvironments: from rational design to bioimaging applications","volume":"56","author":"Fang","year":"2023","journal-title":"Acc. Chem. Res."},{"issue":"4","key":"10.1016\/j.saa.2025.127213_bb0040","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1021\/acs.chemrev.3c00573","article-title":"Design and application of fluorescent probes to detect cellular physical microenvironments","volume":"124","author":"Ma","year":"2024","journal-title":"Chem. Rev."},{"issue":"6","key":"10.1016\/j.saa.2025.127213_bb0045","doi-asserted-by":"crossref","DOI":"10.1002\/ange.202311233","article-title":"Molecular rotors: fluorescent sensors for microviscosity and conformation of biomolecules","volume":"136","author":"Paez-Perez","year":"2024","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.saa.2025.127213_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2023.341776","article-title":"Evaluation of intracellular lipid droplets viscosity by a probe with high fluorescence quantum yield","volume":"1279","author":"Lin","year":"2023","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.saa.2025.127213_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.136441","article-title":"A lipid droplet-targeted NIR fluorescent probe for viscosity detection in Parkinson's disease","volume":"420","author":"Ma","year":"2024","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.saa.2025.127213_bb0060","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.snb.2018.05.055","article-title":"A novel NIR probe for detection of viscosity in cellular lipid droplets, zebra fishes and living mice","volume":"271","author":"Guo","year":"2018","journal-title":"Sens. Actuators B Chem."},{"issue":"1","key":"10.1016\/j.saa.2025.127213_bb0065","doi-asserted-by":"crossref","DOI":"10.1002\/EXP.20230094","article-title":"Wash-free fluorescent tools based on organic molecules: design principles and biomedical applications","volume":"5","author":"Tan","year":"2024","journal-title":"Exploration"},{"issue":"3","key":"10.1016\/j.saa.2025.127213_bb0070","doi-asserted-by":"crossref","DOI":"10.1002\/EXP.20210215","article-title":"Super-resolution analyzing spatial organization of lysosomes with an organic fluorescent probe","volume":"2","author":"Wang","year":"2022","journal-title":"Exploration"},{"issue":"3","key":"10.1016\/j.saa.2025.127213_bb0075","article-title":"Near-infrared aggregation-induced emission materials: bibliometric analysis and their application in biomedical field","volume":"5","author":"He","year":"2024","journal-title":"Aggregate"},{"issue":"12","key":"10.1016\/j.saa.2025.127213_bb0080","doi-asserted-by":"crossref","first-page":"5042","DOI":"10.1016\/j.cclet.2022.03.120","article-title":"BODIPY 493 acts as a bright buffering fluorogenic probe for super-resolution imaging of lipid droplet dynamics","volume":"33","author":"Chen","year":"2022","journal-title":"Chin. Chem. Lett."},{"issue":"11","key":"10.1016\/j.saa.2025.127213_bb0085","doi-asserted-by":"crossref","first-page":"4891","DOI":"10.1021\/cr078381n","article-title":"BODIPY dyes and their derivatives: syntheses and spectroscopic properties","volume":"107","author":"Loudet","year":"2007","journal-title":"Chem. Rev."},{"issue":"8","key":"10.1016\/j.saa.2025.127213_bb0090","doi-asserted-by":"crossref","first-page":"3976","DOI":"10.1039\/D3CS00456B","article-title":"Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy","volume":"53","author":"Wang","year":"2024","journal-title":"Chem. Soc. Rev."},{"issue":"25","key":"10.1016\/j.saa.2025.127213_bb0095","doi-asserted-by":"crossref","first-page":"17334","DOI":"10.1021\/jacs.4c04317","article-title":"Promotion and detection of cell-cell interactions through a bioorthogonal approach","volume":"146","author":"Xue","year":"2024","journal-title":"J. Am. Chem. Soc."},{"issue":"2","key":"10.1016\/j.saa.2025.127213_bb0100","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202214473","article-title":"Toward precise antitumoral photodynamic therapy using a dual receptor-mediated bioorthogonal activation approach","volume":"62","author":"Chu","year":"2023","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.saa.2025.127213_bb0105","doi-asserted-by":"crossref","first-page":"825","DOI":"10.3389\/fchem.2019.00825","article-title":"Functionalized BODIPYs as fluorescent molecular rotors for viscosity detection","volume":"7","author":"Miao","year":"2019","journal-title":"Front. Chem."},{"issue":"8","key":"10.1016\/j.saa.2025.127213_bb0110","doi-asserted-by":"crossref","first-page":"2903","DOI":"10.1021\/ja311688g","article-title":"Activatable rotor for quantifying lysosomal viscosity in living cells","volume":"135","author":"Wang","year":"2013","journal-title":"J. Am. Chem. Soc."},{"issue":"23","key":"10.1016\/j.saa.2025.127213_bb0115","doi-asserted-by":"crossref","first-page":"15308","DOI":"10.1021\/acs.analchem.9b04587","article-title":"Reflecting size differences of exosomes by using the combination of membrane-targeting viscosity probe and fluorescence lifetime imaging microscopy","volume":"91","author":"Li","year":"2019","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2025.127213_bb0120","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.bios.2016.11.018","article-title":"Specifically and wash-free labeling of SNAP-tag fused proteins with a hybrid sensor to monitor local micro-viscosity","volume":"91","author":"Wang","year":"2017","journal-title":"Biosens. Bioelectron."},{"issue":"5","key":"10.1016\/j.saa.2025.127213_bb0125","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.1016\/j.cclet.2021.11.082","article-title":"Forthrightly monitoring ferroptosis induced by endoplasmic reticulum stresses through fluorescence lifetime imaging of microviscosity increases with a specific rotor","volume":"33","author":"Liu","year":"2022","journal-title":"Chinese Chem. Lett."},{"issue":"8","key":"10.1016\/j.saa.2025.127213_bb0130","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1016\/j.cclet.2021.02.031","article-title":"Assessing chromatin condensation for epigenetics with a DNA-targeting sensor by FRET and FLIM techniques","volume":"32","author":"Zhang","year":"2021","journal-title":"Chinese Chem. Lett."},{"issue":"9","key":"10.1016\/j.saa.2025.127213_bb0135","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1039\/C9QM00154A","article-title":"A novel family of AIE-active meso-2-ketopyrrolyl BODIPYs: bright solid-state red fluorescence, morphological properties and application as viscosimeters in live cells","volume":"3","author":"Yu","year":"2019","journal-title":"Mater. Chem. Front."},{"issue":"16","key":"10.1016\/j.saa.2025.127213_bb0140","doi-asserted-by":"crossref","first-page":"4691","DOI":"10.1002\/chem.201304296","article-title":"A \u201cdistorted-BODIPY\u201d-based fluorescent probe for imaging of cellular viscosity in live cells","volume":"20","author":"Zhu","year":"2014","journal-title":"Chem. A Eur. J."},{"key":"10.1016\/j.saa.2025.127213_bb0145","doi-asserted-by":"crossref","unstructured":"W.-J. Shi, J. Yang, Y.-F. Wei, X.-T. Li, X.-H. Yan, Y. Wang, H. Leng, L. Zheng, J.-w. Yan, Novel cationic meso-CF3 BODIPY-based AIE fluorescent rotors for imaging viscosity in mitochondria, Chem. Commun. 58 (12) (2022) 1930\u20131933. Doi: https:\/\/doi.org\/10.1039\/D1CC06532G.","DOI":"10.1039\/D1CC06532G"},{"key":"10.1016\/j.saa.2025.127213_bb0150","doi-asserted-by":"crossref","unstructured":"W.-J. Shi, Y.-F. Wei, J. Yang, H.-Z. Li, Q.-H. Wan, Y. Wang, H. Leng, K. Chen, J.-w. Yan, Novel meso-trifluoromethyl BODIPY-based near-infrared-emitting fluorescent probes for organelle-specific imaging of cellular viscosity, Sens. Actuators B Chem. 359 (2022) 131594. Doi: https:\/\/doi.org\/10.1016\/j.snb.2022.131594.","DOI":"10.1016\/j.snb.2022.131594"},{"key":"10.1016\/j.saa.2025.127213_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2020.129432","article-title":"A conformational transition based fluorescent probe for mapping lysosomal viscosity fluctuations by fluorescence lifetime imaging","volume":"331","author":"Cui","year":"2021","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.saa.2025.127213_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2020.121996","article-title":"Facile mitochondria localized fluorescent probe for viscosity detection in living cells","volume":"225","author":"Sun","year":"2021","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2025.127213_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2019.127271","article-title":"Construction of a red emission BODIPY-based probe for tracing lysosomal viscosity changes in culture cells","volume":"304","author":"Shen","year":"2020","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.saa.2025.127213_bb0170","doi-asserted-by":"crossref","unstructured":"W.-J. Shi, R. Chen, J. Yang, Y.-F. Wei, Y. Guo Z.-Z. Wang, J.-w. Yan, L. Niu, Novel meso-benzothiazole-substituted BODIPY-based AIE fluorescent rotor for imaging lysosomal viscosity and monitoring autophagy, Anal. Chem. 94 (42) (2022) 14707\u201314715. Doi: https:\/\/doi.org\/10.1021\/acs.analchem.2c03094.","DOI":"10.1021\/acs.analchem.2c03094"},{"key":"10.1016\/j.saa.2025.127213_bb0175","doi-asserted-by":"crossref","unstructured":"W.-J. Shi, X.-H. Yan, J. Yang, Y.-F. Wei, Y.-T. Huo, C.-L. Su, J.-w. Yan, D. Han, L. Niu, Development of meso-five-membered heterocycle BODIPY-based AIE gluorescent probes for dual-organelle viscosity imaging, Anal. Chem. 95 (25) (2023) 9646\u20139653. Doi: https:\/\/doi.org\/10.1021\/acs.analchem.3c01409.","DOI":"10.1021\/acs.analchem.3c01409"},{"key":"10.1016\/j.saa.2025.127213_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2024.124356","article-title":"Construction and evaluation of near-infrared fluorescent probes for imaging lipid droplet and lysosomal viscosity","volume":"316","author":"Li","year":"2024","journal-title":"Spectrochim. Acta A"},{"key":"10.1016\/j.saa.2025.127213_bb0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2024.126362","article-title":"Development of BODIPY-based fluorescent probes for imaging A\u03b2 aggregates and lipid droplet viscosity","volume":"277","author":"Li","year":"2024","journal-title":"Talanta"},{"issue":"8","key":"10.1016\/j.saa.2025.127213_bb0190","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1007\/s11426-023-1661-6","article-title":"Synergistic effects of multiple rotors and hydrogen-bond interactions lead to sensitive near-infrared viscosity probes for live-cell microscopy","volume":"66","author":"Li","year":"2023","journal-title":"Sci. China Chem."},{"issue":"6","key":"10.1016\/j.saa.2025.127213_bb0195","doi-asserted-by":"crossref","first-page":"4177","DOI":"10.1021\/acs.analchem.0c00634","article-title":"Design of activatable NIR-II molecular probe for in vivo elucidation of disease-related viscosity variations","volume":"92","author":"Dou","year":"2020","journal-title":"Anal. Chem."},{"issue":"26","key":"10.1016\/j.saa.2025.127213_bb0200","doi-asserted-by":"crossref","first-page":"8490","DOI":"10.1021\/jacs.5b03248","article-title":"F\u00f6rster resonance energy transfer switchable self-assembled micellar nanoprobe: Ratiometric fluorescent trapping of endogenous H2S generation via fluvastatin-stimulated upregulation","volume":"137","author":"Zhao","year":"2015","journal-title":"J. Am. Chem. Soc."},{"issue":"14","key":"10.1016\/j.saa.2025.127213_bb0205","doi-asserted-by":"crossref","first-page":"3626","DOI":"10.1002\/anie.201712528","article-title":"Imaging of colorectal cancers using activatable nanoprobes with second near-infrared window emission","volume":"57","author":"Xu","year":"2018","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.saa.2025.127213_bb0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmcl.2022.128544","article-title":"An activatable fluorescent probe for imaging endogenous nitric oxide via the eNOS enzymatic pathway","volume":"59","author":"Ouyang","year":"2022","journal-title":"Bioorg. Med. Chem. Lett."},{"issue":"4","key":"10.1016\/j.saa.2025.127213_bb0215","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1023\/B:JOFL.0000031828.96368.c1","article-title":"Corrected emission spectra and quantum yields for a series of fluorescent compounds in the visible spectral region","volume":"14","author":"Velapoldi","year":"2004","journal-title":"J. Fluoresc."},{"issue":"23","key":"10.1016\/j.saa.2025.127213_bb0220","doi-asserted-by":"crossref","first-page":"6590","DOI":"10.1021\/j100334a023","article-title":"Effect of solvent polarity on nonradiative processes in xanthene dyes: rhodamine B in normal alcohols","volume":"92","author":"Casey","year":"1988","journal-title":"J. Phys. Chem."},{"key":"10.1016\/j.saa.2025.127213_bb0225","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s10895-013-1304-9","article-title":"Fluorescence-based broad dynamic range viscosity probes","volume":"24","author":"Dragan","year":"2014","journal-title":"J. Fluoresc."},{"key":"10.1016\/j.saa.2025.127213_bb0230","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s41664-022-00247-7","article-title":"Fast response fluorescent probe with a large Stokes shift for thiophenol detection in water samples and cell imaging","volume":"7","author":"You","year":"2023","journal-title":"J. Anal. Test."}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142525015215?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142525015215?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T13:13:31Z","timestamp":1766150011000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386142525015215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":46,"alternative-id":["S1386142525015215"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2025.127213","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Construction of dual-rotor-BODIPY-based fluorescent probes with improved sensitivity and brightness for lipid-droplet viscosity imaging","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2025.127213","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"127213"}}