{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T02:45:56Z","timestamp":1786243556492,"version":"build-2736575974"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.saa.2026.128471","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T23:33:57Z","timestamp":1784244837000},"page":"128471","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"P1","title":["Ligand-regulated Cu-BH enhanced luminol chemiluminescence for sensitive detection of p-phenylenediamine in water samples"],"prefix":"10.1016","volume":"363","author":[{"given":"Jing","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqian","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Funan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2026.128471_bb0005","doi-asserted-by":"crossref","first-page":"6800","DOI":"10.1039\/D0CS00348D","article-title":"Chemiluminescence for bioimaging and therapeutics: recent advances and challenges","volume":"49","author":"Yang","year":"2020","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.saa.2026.128471_bb0010","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1021\/acs.analchem.7b04544","article-title":"Self-Catalyzing chemiluminescence of luminol-diazonium ion and its application for catalyst-free hydrogen peroxide detection and rat arthritis imaging","volume":"90","author":"Zhao","year":"2018","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2026.128471_bb0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2023.109856","article-title":"Intelligent chemiluminescent system for wash-free and ultrasensitive assay of aflatoxin B1 in coix seed and decoction pieces","volume":"197","author":"Zhang","year":"2024","journal-title":"Microchem. J."},{"key":"10.1016\/j.saa.2026.128471_bb0020","doi-asserted-by":"crossref","first-page":"2602","DOI":"10.1039\/C4SC03809F","article-title":"High-throughput imaging assay of multiple proteins via target-induced DNA assembly and cleavage","volume":"6","author":"Zong","year":"2015","journal-title":"Chem. Sci."},{"key":"10.1016\/j.saa.2026.128471_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2022.123906","article-title":"Recent progress in assembly strategies of nanomaterials-based ultrasensitive electrochemiluminescence biosensors for food safety and disease diagnosis","volume":"253","author":"Peng","year":"2023","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2026.128471_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2025.159477","article-title":"Phosphorus nitride dot-activated ferrate (VI) with enhanced singlet oxygen mediating chemiluminescence for pyroquilon determination","volume":"505","author":"Gou","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.saa.2026.128471_bb0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2024.343182","article-title":"Glow-type luminol chemiluminescence based on a supramolecular enhancer of cyclodextrin","volume":"1328","author":"Hu","year":"2024","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.saa.2026.128471_bb0040","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1515\/zpch-1928-13625","article-title":"\u00dcber die Chemiluminescenz des Aminophthals\u00e4urehydrazids","volume":"136U","author":"Albrecht","year":"1928","journal-title":"Z. Phys. Chem."},{"key":"10.1016\/j.saa.2026.128471_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2025.112774","article-title":"Detection of acetylcholinesterase based on ECL resonance energy transfer between luminol and gold nanoparticle decorated covalent organic framework","volume":"209","author":"Wang","year":"2025","journal-title":"Microchem. J."},{"key":"10.1016\/j.saa.2026.128471_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2025.113332","article-title":"High-entropy metal-organic-framework nanosheets enhanced luminol\/H2O2 chemiluminescence for ultrasensitive dopamine detection","volume":"212","author":"Tessema","year":"2025","journal-title":"Microchem. J."},{"key":"10.1016\/j.saa.2026.128471_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2023.341959","article-title":"Metal-organic framework (MOF)-derived flower-like Ni-MOF@NiV-layered double hydroxides as peroxidase mimetics for colorimetric detection of hydroquinone","volume":"1283","author":"He","year":"2023","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.saa.2026.128471_bb0060","doi-asserted-by":"crossref","first-page":"23269","DOI":"10.1021\/acs.analchem.5c03590","article-title":"Multifunctional dual-ligand MOF for capture, imaging, and photodynamic clearance of circulating tumor cells","volume":"97","author":"Hao","year":"2025","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2026.128471_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2025.143679","article-title":"Self-luminescent dual-ligand metal-organic framework based electrochemiluminescence probes for organophosphorus pesticides determination","volume":"478","author":"Shen","year":"2025","journal-title":"Food Chem."},{"key":"10.1016\/j.saa.2026.128471_bb0070","article-title":"Efficient electrochemiluminescence sensor utilizing Zr-PyTCPPMOF for swift hydrogen sulfide detection","volume":"192","author":"Chen","year":"2024","journal-title":"Microchim. Acta"},{"key":"10.1016\/j.saa.2026.128471_bb0075","article-title":"A nitro functionalized MOF with multi-enzyme mimetic activities for the colorimetric sensing of glucose at neutral pH","volume":"23","author":"Wang","year":"2023","journal-title":"Sensors"},{"key":"10.1016\/j.saa.2026.128471_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2022.131927","article-title":"Histidine-engineered metal-organic frameworks with enhanced peroxidase-like activity for sensitive detection of metallothioneins","volume":"366","author":"Sha","year":"2022","journal-title":"Sens. Actuators B"},{"key":"10.1016\/j.saa.2026.128471_bb0085","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1039\/D5TB02348C","article-title":"Application of copper based single-atom nanozymes in wound healing and tumor treatment","volume":"14","author":"He","year":"2026","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.saa.2026.128471_bb0090","article-title":"Cu-Fe oxide nanozymes with enhanced peroxidase-like activity for sensitive H2O2 colorimetric detection","author":"Jiang","year":"2026","journal-title":"Korean J. Chem. Eng."},{"key":"10.1016\/j.saa.2026.128471_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2022.114294","article-title":"Controllable synthesis of boron-doped Zn\u2013N\u2013C single-atom nanozymes for the ultrasensitive colorimetric detection of p-phenylenediamine","volume":"210","author":"Feng","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.saa.2026.128471_bb0100","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.cclet.2021.08.083","article-title":"Fluorescent MOF-based nanozymes for discrimination of phenylenediamine isomers and ratiometric sensing of o-phenylenediamine","volume":"33","author":"Xia","year":"2022","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.saa.2026.128471_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.cclet.2025.111323","article-title":"CoPt graphitic nanozyme enabled naked-eye identification and colorimetric\/fluorescent dual-mode detection of phenylenediamine isomers","volume":"37","author":"Guan","year":"2026","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.saa.2026.128471_bb0110","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.freeradbiomed.2026.01.048","article-title":"Assessment of p-phenylenediamine toxicity in subcellular compartments of hepatic and ocular tissues in Oreochromis mossambicus (Peters, 1852)","volume":"246","author":"Amrutha","year":"2026","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.saa.2026.128471_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.136269","article-title":"P-phenylenediamines (PPDs) and 6PPD-quinone in tunnel PM2.5: from the perspective of characterization, emission factors, and health risks","volume":"480","author":"Jiang","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.saa.2026.128471_bb0120","article-title":"Participation of lattice oxygen in perovskite oxide as a highly sensitive sensor for p-phenylenediamine detection","volume":"28","author":"He","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.saa.2026.128471_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2025.166988","article-title":"An ultrastable tetraazacalix[2]arene[2]triazine functionalized MXene for highly selective and sensitive determination of p-phenylenediamines and their quinone derivatives in environmental water via HPLC-MS\/MS","volume":"522","author":"Huo","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.saa.2026.128471_bb0130","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-026-50484-4","article-title":"Machine learning-assisted paper-based chemiluminescence biosensor for choline quantification in infant milk: toward portable nutritional quality monitoring","volume":"16","author":"Zalke","year":"2026","journal-title":"Sci. Rep."},{"key":"10.1016\/j.saa.2026.128471_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2025.138746","article-title":"Bioinspired HOF nanozyme-enhanced hydrogel biosensor for smartphone-assisted detection of organophosphorus pesticide residues","volume":"446","author":"Zhu","year":"2026","journal-title":"Sens. Actuators B"},{"key":"10.1016\/j.saa.2026.128471_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2026.130173","article-title":"Smartphone-integrated bifunctional sensing platform for visual detection of ampicillin and tetracycline in animal manure","volume":"310","author":"Chen","year":"2026","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2026.128471_bb0145","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1021\/acssensors.2c02791","article-title":"Highly stable Fe\/Co-TPY-MIL-88(NH2) metal\u2013organic framework (MOF) in enzymatic cascade reactions for chemiluminescence-based detection of extracellular vesicles","volume":"8","author":"Jiang","year":"2023","journal-title":"ACS Sens."},{"key":"10.1016\/j.saa.2026.128471_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2024.127417","article-title":"Copper-based fluorescent nanozyme used to construct a ratiometric sensor for visual detection of thiophanate methyl","volume":"285","author":"Liu","year":"2025","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2026.128471_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2025.102634","article-title":"Precisely mimicking lipoxidase with histidine coordinated Fe-MOF for temperature-adaptive antiviral protection","volume":"61","author":"Zhong","year":"2025","journal-title":"Nano Today"},{"key":"10.1016\/j.saa.2026.128471_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2025.117533","article-title":"Histidine-engineered Cu-BTC nanozyme with enhanced laccase-like activity combining the machine learning for precise recognition of Beta-lactam antibiotics","volume":"283","author":"Xu","year":"2025","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.saa.2026.128471_bb0165","first-page":"769","article-title":"S-doped Fe\u2013N\u2013C single-atom nanozyme with enhanced oxidase-like activity for colorimetric detection of serotonin","volume":"18","author":"Zhang","year":"2026","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.saa.2026.128471_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2025.127325","article-title":"Ultrasensitive determination of aflatoxin B1 by flow injection chemiluminescence immunoassay based on hemin-integrated Tb-MOF(Fe) nanozyme","volume":"349","author":"Wang","year":"2026","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2026.128471_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.jssc.2022.122888","article-title":"Composite of magnetic carbon quantum dot-supported ionic liquid and Cu-BDC (CCDC no. 687690) MOF: a triple catalytic composite for chemical transformations","volume":"308","author":"Sadjadi","year":"2022","journal-title":"J. Solid State Chem."},{"key":"10.1016\/j.saa.2026.128471_bb0180","doi-asserted-by":"crossref","first-page":"6347","DOI":"10.1021\/acs.analchem.5c00745","article-title":"Electrochemical sensing of perfluorooctanoic acid via a rationally designed fluorine-functionalized Cu-MOF and in-depth analysis of sensing mechanism","volume":"97","author":"Zheng","year":"2025","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2026.128471_bb0185","doi-asserted-by":"crossref","DOI":"10.1002\/elan.202100423","article-title":"2-methylimidazole-assisted morphology modulation of a copper-based metal-organic framework transducer for enhanced electrochemical peroxidase-like activity","volume":"35","author":"Li","year":"2023","journal-title":"Electroanalysis"},{"key":"10.1016\/j.saa.2026.128471_bb0190","article-title":"Construction of a laccase mimic enzyme with fluorescence properties for kanamycin multi-mode analysis","volume":"471","author":"Li","year":"2023","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.saa.2026.128471_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2026.139448","article-title":"Switchable hydrogen bond network regulates aggregation and dispersion of metal\u2013organic frameworks for multimodal anticounterfeiting","volume":"452","author":"Yang","year":"2026","journal-title":"Sens. Actuators B"},{"key":"10.1016\/j.saa.2026.128471_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.152630","article-title":"Optimization of metal\u2013organic framework nanozyme activity via histidine modification for simultaneous pesticide detection","volume":"493","author":"Yue","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.saa.2026.128471_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2024.112403","article-title":"Rapid synthesis of multifunctional copper nanoclusters for selective and sensitive detection of hexavalent chromium and anti-counterfeiting","volume":"208","author":"Liang","year":"2025","journal-title":"Microchem. J."},{"key":"10.1016\/j.saa.2026.128471_bb0210","doi-asserted-by":"crossref","first-page":"8352","DOI":"10.1021\/acsanm.1c01539","article-title":"NH2-UiO-66 metal\u2013organic framework nanoparticles for hydroxide ion conductive photoswitches","volume":"4","author":"Wang","year":"2021","journal-title":"ACS Appl. Nano Mater."},{"key":"10.1016\/j.saa.2026.128471_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.128536","article-title":"Fabrication of Cu(BDC)0.5(BDC-NH2)0.5 metal-organic framework for superior H2S removal at room temperature","volume":"411","author":"Gupta","year":"2021","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.saa.2026.128471_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.inoche.2024.113228","article-title":"Cu-MOF nanosheets with laccase-like activity for phenolic compounds detection and dye removal","volume":"170","author":"Yang","year":"2024","journal-title":"Inorg. Chem. Commun."},{"key":"10.1016\/j.saa.2026.128471_bb0225","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1039\/C9CC08311A","article-title":"Highly active metal-free peroxidase mimics based on oxygen-doped carbon nitride by promoting electron transfer capacity","volume":"56","author":"Zhu","year":"2020","journal-title":"Chem. Commun."},{"key":"10.1016\/j.saa.2026.128471_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2022.123724","article-title":"Enhancement effect of 2, 3-dimethyl maleic acid on luminol chemiluminescence reactions and its application in detection of sequence-specific DNA related to hepatitis B virus","volume":"250","author":"Liu","year":"2022","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2026.128471_bb0235","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1021\/acs.analchem.5c05879","article-title":"UV-mediated enzyme-like activity reversal strategy to regulate nanozymes for detection and elimination of Bacteria","volume":"98","author":"Peng","year":"2026","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2026.128471_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2026.345114","article-title":"Highly sensitive chemiluminescence immunoassay utilizing functionalized magnetic metal-organic framework materials for the detection of CEA and CA199","volume":"1389","author":"Zuo","year":"2026","journal-title":"Anal. Chim. Acta"}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142526010425?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142526010425?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T02:39:16Z","timestamp":1786243156000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386142526010425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":48,"alternative-id":["S1386142526010425"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2026.128471","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ligand-regulated Cu-BH enhanced luminol chemiluminescence for sensitive detection of p-phenylenediamine in water samples","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2026.128471","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"128471"}}