{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:00:51Z","timestamp":1790625651541,"version":"4.1.0"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82460695"],"award-info":[{"award-number":["82460695"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.saa.2026.128706","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T16:07:55Z","timestamp":1788538075000},"page":"128706","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["A D-\u03c0-A conjugated probe with dual responses to bisulfite and microenvironmental viscosity\/polarity for imaging ferroptosis in neural cells"],"prefix":"10.1016","volume":"365","author":[{"given":"Xinyue","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Furong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.saa.2026.128706_bb0005","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.tins.2025.06.008","article-title":"Triggering ferroptosis in neurodegenerative diseases","volume":"48","author":"Nguyen","year":"2025","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.saa.2026.128706_bb0010","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/j.tips.2023.07.007","article-title":"Therapeutic inhibition of ferroptosis in neurodegenerative disease","volume":"44","author":"Ryan","year":"2023","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.saa.2026.128706_bb0015","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.657033","article-title":"Mechanisms of modulation of ferroptosis and its role in central nervous system diseases","volume":"12","author":"Tan","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.saa.2026.128706_bb0020","doi-asserted-by":"crossref","first-page":"395","DOI":"10.3390\/antiox13040395","article-title":"The interplay between ferroptosis and neuroinflammation in central neurological disorders","volume":"13","author":"Xu","year":"2024","journal-title":"Antioxidants"},{"key":"10.1016\/j.saa.2026.128706_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2025.103788","article-title":"DHODH-mediated mitochondrial redox homeostasis: a novel ferroptosis regulator and promising therapeutic target","volume":"85","author":"Cao","year":"2025","journal-title":"Redox Biol."},{"key":"10.1016\/j.saa.2026.128706_bb0030","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/s41420-023-01407-z","article-title":"Ferroptosis in lung cancer: a novel pathway regulating cell death and a promising target for drug therapy","volume":"9","author":"Xing","year":"2023","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.saa.2026.128706_bb0035","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.26599\/FSHW.2022.9250204","article-title":"Mechanisms and active substances of targeting lipid peroxidation in ferroptosis regulation","volume":"13","author":"Chen","year":"2024","journal-title":"Food Sci. Human Wellness"},{"key":"10.1016\/j.saa.2026.128706_bb0040","doi-asserted-by":"crossref","DOI":"10.3390\/ijms27083353","article-title":"Impact of oxidative stress-driven ferroptosis in neurodegeneration","volume":"27","author":"Rafique","year":"2026","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.saa.2026.128706_bb0045","doi-asserted-by":"crossref","first-page":"9637","DOI":"10.3390\/ijms24119637","article-title":"Iron and Ferroptosis More than a suspect: beyond the Most common mechanisms of neurodegeneration for new therapeutic approaches to cognitive decline and dementia","volume":"24","author":"Cerasuolo","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.saa.2026.128706_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.115656","article-title":"Molecular mechanism and potential therapeutic targets of necroptosis and ferroptosis in Alzheimer\u2019s disease","volume":"168","author":"Chavoshinezhad","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.saa.2026.128706_bb0055","doi-asserted-by":"crossref","first-page":"18301","DOI":"10.1021\/jacs.9b09722","article-title":"Ferroptosis accompanied by \u2022OH generation and cytoplasmic viscosity increase revealed via dual-functional fluorescence probe","volume":"141","author":"Li","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.saa.2026.128706_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2025.344710","article-title":"An engineered single-wavelength-excitable dual-color fluorescent probe for simultaneous imaging of polarity and viscosity dynamics during ferroptosis","volume":"1379","author":"Yu","year":"2025","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.saa.2026.128706_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.136030","article-title":"Dual-ratiometric fluorescent probes for monitoring ClO- and polarity dynamics in ferroptosis","volume":"415","author":"He","year":"2024","journal-title":"Sens. Actuators B"},{"key":"10.1016\/j.saa.2026.128706_bb0070","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1039\/D2CS00454B","article-title":"Fluorescent probes for ferroptosis bioimaging: advances, challenges, and prospects","volume":"52","author":"Yin","year":"2023","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.saa.2026.128706_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2020.108252","article-title":"Sulfur dioxide derivatives produce antidepressant- and anxiolytic-like effects in mice","volume":"176","author":"Shi","year":"2020","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.saa.2026.128706_bb0080","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ejphar.2014.08.025","article-title":"Effects of gaseous sulfur dioxide and its derivatives on the expression of KATP, BKCa and L-Ca2+ channels in rat aortas in vitro","volume":"742","author":"Zhang","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.saa.2026.128706_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.neurot.2025.e00633","article-title":"The Yin-Yang of sulfur dioxide: effect on cognitive function","volume":"22","author":"Dobariya","year":"2025","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.saa.2026.128706_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2022.131937","article-title":"A bifunctional fluorescent probe for imaging lipid droplets polarity\/SO2 during ferroptosis","volume":"365","author":"Xie","year":"2022","journal-title":"Sens. Actuators B"},{"key":"10.1016\/j.saa.2026.128706_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.136470","article-title":"Dynamic monitoring of SO2 changes during ferroptosis using a light-controlled lipid droplets-targeting probe","volume":"420","author":"Wang","year":"2024","journal-title":"Sens. Actuators B"},{"key":"10.1016\/j.saa.2026.128706_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2023.117327","article-title":"Recent advance in the development of the fluorescent responsive probes for the study of ferroptosis","volume":"168","author":"Dong","year":"2023","journal-title":"TrAC Trends Anal. Chem."},{"key":"10.1016\/j.saa.2026.128706_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2023.124628","article-title":"Fluorescent probes for lighting up ferroptotic cell death: a review","volume":"260","author":"Yang","year":"2023","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2026.128706_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2024.124246","article-title":"Targeted mitochondrial fluorescence probe with large stokes shift for detecting viscosity changes in vivo and in ferroptosis process","volume":"315","author":"Tan","year":"2024","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2026.128706_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2023.215432","article-title":"Endogenous molecule-targeted fluorescent probes for ferroptosis visualization: current progress and future prospects","volume":"496","author":"Shu","year":"2023","journal-title":"Coord. Chem. Rev."},{"key":"10.1016\/j.saa.2026.128706_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2024.124123","article-title":"Development of a turn-on fluorescent probe for the imaging of intracellular hypochlorous acid (HClO) during ferroptosis","volume":"313","author":"Wang","year":"2024","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2026.128706_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2025.112879","article-title":"Lipid droplets-targetable fluorescent probe for monitoring polarity changes during ferroptosis","volume":"241","author":"Zhou","year":"2025","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.saa.2026.128706_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2025.127099","article-title":"Lipid droplet-targeted fluorescent probes for polarity sensing in ferroptosis cellular models and in vivo zebrafish","volume":"348","author":"Han","year":"2026","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2026.128706_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2024.343570","article-title":"Preparation, mechanism, and biological applications of targeting LDs ratiometric fluorescent probes for HClO detection","volume":"1337","author":"Yan","year":"2025","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.saa.2026.128706_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2025.129010","article-title":"A dual-responsive fluorescent probe for hypochlorous acid and copper(II): design, environmental applications, and signal transduction mechanism","volume":"298","author":"Yan","year":"2026","journal-title":"Talanta"},{"key":"10.1016\/j.saa.2026.128706_bb0145","doi-asserted-by":"crossref","first-page":"5615","DOI":"10.1021\/acs.analchem.4c00227","article-title":"Dual-functional AIE fluorescent probe for visualization of lipid droplets and photodynamic therapy of cancer","volume":"96","author":"Pei","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.saa.2026.128706_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2019.117788","article-title":"A novel ratiometric fluorescent probe for \u201cnaked-eye\u201d detection of sulfite ion: applications in detection of biological SO32\u2212 ions in food and live cells","volume":"228","author":"Venkatachalam","year":"2020","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2026.128706_bb0155","doi-asserted-by":"crossref","first-page":"10899","DOI":"10.1021\/acs.jafc.2c04571","article-title":"Novel colorimetric and NIR fluorescent probe for bisulfite\/sulfite detection in food and water samples and living cells based on the PET mechanism","volume":"70","author":"Li","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.saa.2026.128706_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2022.121160","article-title":"A quinoline-based probe for the ratiometric fluorescent detection of sulfite in lysosomes of living cells","volume":"275","author":"Li","year":"2022","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2026.128706_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2024.124747","article-title":"Phenanthroimidazole-based fluorescence probe for discriminative detecting of hydrazine and bisulfite and its applications in environmental samples","volume":"321","author":"Shi","year":"2024","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.saa.2026.128706_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2025.344558","article-title":"A FRET ratiometric fluorescent probe for detection of bisulfite in food: insights into food quality and preservation","volume":"1373","author":"Dong","year":"2025","journal-title":"Anal. Chim. Acta"}],"container-title":["Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142526012771?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386142526012771?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:25:22Z","timestamp":1790623522000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386142526012771"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":34,"alternative-id":["S1386142526012771"],"URL":"https:\/\/doi.org\/10.1016\/j.saa.2026.128706","relation":{},"ISSN":["1386-1425"],"issn-type":[{"value":"1386-1425","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A D-\u03c0-A conjugated probe with dual responses to bisulfite and microenvironmental viscosity\/polarity for imaging ferroptosis in neural cells","name":"articletitle","label":"Article Title"},{"value":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.saa.2026.128706","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"128706"}}