{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T05:21:50Z","timestamp":1784784110629,"version":"3.55.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002842","name":"Chiang Mai University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002842","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Social and Administrative Pharmacy"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.sapharm.2021.01.003","type":"journal-article","created":{"date-parts":[[2021,1,9]],"date-time":"2021-01-09T19:56:46Z","timestamp":1610222206000},"page":"1631-1635","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Association between medication adherence and cardiovascular outcomes among acute coronary syndrome patients"],"prefix":"10.1016","volume":"17","author":[{"given":"Surarong","family":"Chinwong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kodchawan","family":"Doungsong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preeyarat","family":"Channaina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arintaya","family":"Phrommintikul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dujrudee","family":"Chinwong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sapharm.2021.01.003_bib1","unstructured":"World Helalth Organization. The top 10 causes of death. Available from: https:\/\/www.who.int\/en\/news-room\/fact-sheets\/detail\/the-top-10-causes-of-death. Accessed: 20.12.19."},{"key":"10.1016\/j.sapharm.2021.01.003_bib2","doi-asserted-by":"crossref","first-page":"s43","DOI":"10.7861\/clinmedicine.16-6-s43","article-title":"Acute coronary syndromes","volume":"16","author":"Kotecha","year":"2016","journal-title":"Clin Med"},{"key":"10.1016\/j.sapharm.2021.01.003_bib3","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1136\/bmj.326.7404.1419","article-title":"A strategy to reduce cardiovascular disease by more than 80%","volume":"326","author":"Wald","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.sapharm.2021.01.003_bib4","first-page":"e344","article-title":"2014 AHA\/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology\/American Heart Association Task Force on practice guidelines","volume":"130","author":"Amsterdam","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.sapharm.2021.01.003_bib5","doi-asserted-by":"crossref","first-page":"e362","DOI":"10.1161\/CIR.0b013e3182742c84","article-title":"2013 ACCF\/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on practice guidelines","volume":"127","author":"O\u2019Gara","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.sapharm.2021.01.003_bib6","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1093\/eurheartj\/ehv320","volume":"37","author":"Roffi","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.sapharm.2021.01.003_bib7","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1093\/eurheartj\/ehs215","article-title":"ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation","volume":"33","author":"Steg","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.sapharm.2021.01.003_bib8","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1046\/j.1365-2125.2000.00287.x","article-title":"Drugs used in secondary prevention after myocardial infarction: case presentation","volume":"50","author":"Maxwell","year":"2000","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.sapharm.2021.01.003_bib9","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.recesp.2014.04.015","article-title":"Update: acute coronary syndromes (IX). Secondary prevention strategies for acute coronary syndrome","volume":"67","author":"Quiles","year":"2014","journal-title":"Rev Esp Cardiol"},{"key":"10.1016\/j.sapharm.2021.01.003_bib10","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.011793","article-title":"Association between medication adherence and 1-year major cardiovascular adverse events after acute myocardial infarction in China","volume":"8","author":"Shang","year":"2019","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.sapharm.2021.01.003_bib11","doi-asserted-by":"crossref","first-page":"3028","DOI":"10.1161\/CIRCULATIONAHA.108.768986","article-title":"Medication adherence: its importance in cardiovascular outcomes","volume":"119","author":"Ho","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.sapharm.2021.01.003_bib12","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.sapharm.2017.06.004","article-title":"Effect of pharmacist care on medication adherence and cardiovascular outcomes among patients post-acute coronary syndrome: a systematic review","volume":"14","author":"El Hajj","year":"2018","journal-title":"Res Soc Adm Pharm"},{"key":"10.1016\/j.sapharm.2021.01.003_bib13","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.amjmed.2011.12.013","article-title":"Adherence to drugs that prevent cardiovascular disease: meta-analysis on 376,162 patients","volume":"125","author":"Naderi","year":"2012","journal-title":"Am J Med"},{"key":"10.1016\/j.sapharm.2021.01.003_bib14","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.amjmed.2013.01.033","article-title":"Adherence to secondary prevention medications and four-year outcomes in outpatients with atherosclerosis","volume":"126","author":"Kumbhani","year":"2013","journal-title":"Am J Med"},{"key":"10.1016\/j.sapharm.2021.01.003_bib15","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.ahj.2007.12.011","article-title":"Medication nonadherence is associated with a broad range of adverse outcomes in patients with coronary artery disease","volume":"155","author":"Ho","year":"2008","journal-title":"Am Heart J"},{"key":"10.1016\/j.sapharm.2021.01.003_bib16","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.jacc.2016.06.005","article-title":"Assessing the impact of medication adherence on long-term cardiovascular outcomes","volume":"68","author":"Bansilal","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.sapharm.2021.01.003_bib17","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1001\/jama.297.2.177","article-title":"Relationship between adherence to evidence-based pharmacotherapy and long-term mortality after acute myocardial infarction","volume":"297","author":"Rasmussen","year":"2007","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.sapharm.2021.01.003_bib18","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1001\/archinte.167.16.1798","article-title":"Self-reported medication adherence and cardiovascular events in patients with stable coronary heart disease: the heart and soul study","volume":"167","author":"Gehi","year":"2007","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.sapharm.2021.01.003_bib19","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.hrtlng.2018.09.009","article-title":"Relationship of medication adherence and quality of life among heart failure patients","volume":"48","author":"Silavanich","year":"2019","journal-title":"Heart Lung"},{"key":"10.1016\/j.sapharm.2021.01.003_bib20","unstructured":"Faculty of Medicine Chiang Mai University. Maharaj Nakorn Chiang Mai Hospital. Available from: https:\/\/www.med.cmu.ac.th\/en\/service\/suandok\/Accessed: 10.06.20."},{"key":"10.1016\/j.sapharm.2021.01.003_bib21","first-page":"659","article-title":"Low-density lipoprotein cholesterol of less than 70 mg\/dL is associated with fewer cardiovascular events in acute coronary syndrome patients: a real-life cohort in Thailand","volume":"11","author":"Chinwong","year":"2015","journal-title":"Ther Clin Risk Manag"},{"key":"10.1016\/j.sapharm.2021.01.003_bib22","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1056\/NEJMra050100","article-title":"Adherence to medication","volume":"353","author":"Osterberg","year":"2005","journal-title":"N Engl J Med"},{"issue":"Suppl 1","key":"10.1016\/j.sapharm.2021.01.003_bib23","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1016\/S0895-4356(01)00457-7","article-title":"Treatment adherence in chronic disease","volume":"54","author":"Dunbar-Jacob","year":"2001","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.sapharm.2021.01.003_bib24","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1001\/jama.2018.19271","article-title":"Interventions to improve medication adherence: a review","volume":"320","author":"Kini","year":"2018","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.sapharm.2021.01.003_bib25","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0895-4356(96)00268-5","article-title":"The assessment of refill compliance using pharmacy records: methods, validity, and applications","volume":"50","author":"Steiner","year":"1997","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.sapharm.2021.01.003_bib26","series-title":"Presented at the 15th Asian Conference on Clinical Pharmacy","article-title":"Statin adherence and LDL-C goal attainment in type 2 diabetic patients","author":"Saithong","year":"2015"},{"key":"10.1016\/j.sapharm.2021.01.003_bib27","series-title":"Regression Methods in Biostatistics: Linear, Logistic, Survival, and Repeated Measures Models","author":"Vittinghoff","year":"2005"},{"key":"10.1016\/j.sapharm.2021.01.003_bib28","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1002\/pds.1671","article-title":"Trends in adherence to secondary prevention medications in elderly post-myocardial infarction patients","volume":"17","author":"Choudhry","year":"2008","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1016\/j.sapharm.2021.01.003_bib29","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1001\/archinte.166.17.1829","article-title":"Cost-related medication nonadherence among elderly and disabled medicare beneficiaries: a national survey 1 year before the medicare drug benefit","volume":"166","author":"Soumerai","year":"2006","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.sapharm.2021.01.003_bib30","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s40271-014-0099-3","article-title":"Understanding patient preferences in dedication nonadherence: a review of stated preference data","volume":"8","author":"Laba","year":"2015","journal-title":"Patient"},{"issue":"Suppl 1","key":"10.1016\/j.sapharm.2021.01.003_bib31","doi-asserted-by":"crossref","first-page":"S137","DOI":"10.1111\/j.1524-4733.2008.00378.x","article-title":"Health-care systems and pharmacoeconomic research in Asia-Pacific region","volume":"11","author":"Tarn","year":"2008","journal-title":"Value Health"},{"key":"10.1016\/j.sapharm.2021.01.003_bib32","first-page":"1","article-title":"Poor adherence to beta-blockers is associated with increased long-term mortality even beyond the first year after an acute coronary syndrome event","author":"Allonen","year":"2020","journal-title":"Ann Med"},{"issue":"8","key":"10.1016\/j.sapharm.2021.01.003_bib33","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1002\/ejhf.592","volume":"18","author":"Ponikowski","year":"2016","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.sapharm.2021.01.003_bib34","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/pds.1698","article-title":"Comparison of various measures for assessing medication refill adherence using prescription data","volume":"18","author":"Vink","year":"2009","journal-title":"Pharmacoepidemiol Drug Saf"}],"container-title":["Research in Social and Administrative Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551741121000231?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551741121000231?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T09:24:51Z","timestamp":1761557091000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1551741121000231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":34,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S1551741121000231"],"URL":"https:\/\/doi.org\/10.1016\/j.sapharm.2021.01.003","relation":{},"ISSN":["1551-7411"],"issn-type":[{"value":"1551-7411","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between medication adherence and cardiovascular outcomes among acute coronary syndrome patients","name":"articletitle","label":"Article Title"},{"value":"Research in Social and Administrative Pharmacy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sapharm.2021.01.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}