{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T16:52:45Z","timestamp":1781542365936,"version":"3.54.5"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001779","name":"Monash University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001779","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000991","name":"Faculty of Medicine, Nursing and Health Sciences, Monash University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000991","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Opinion in Structural Biology"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.sbi.2026.103221","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T03:56:30Z","timestamp":1770868590000},"page":"103221","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Structural biology of \u03b3\u03b4 T cell receptors"],"prefix":"10.1016","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-7271-229X","authenticated-orcid":false,"given":"Liam","family":"Rashleigh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0527-5906","authenticated-orcid":false,"given":"Mengqi","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2020-7522","authenticated-orcid":false,"given":"Jamie","family":"Rossjohn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2693-0252","authenticated-orcid":false,"given":"Michael T.","family":"Rice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sbi.2026.103221_bib1","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1002\/JLB.2MR1219-233R","article-title":"Alphabeta and gammadelta T cell receptors: similar but different","volume":"107","author":"Morath","year":"2020","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.sbi.2026.103221_bib2","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1126\/science.274.5285.209","article-title":"An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex","volume":"274","author":"Garcia","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103221_bib3","doi-asserted-by":"crossref","first-page":"eabe9124","DOI":"10.1126\/science.abe9124","article-title":"Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling","volume":"372","author":"Zareie","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103221_bib4","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1084\/jem.179.1.323","article-title":"CDR3 length in antigen-specific immune receptors","volume":"179","author":"Rock","year":"1994","journal-title":"J Exp Med"},{"key":"10.1016\/j.sbi.2026.103221_bib5","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2315592121","article-title":"Gammadelta T cell antigen receptor polyspecificity enables T cell responses to a broad range of immune challenges","volume":"121","author":"Guo","year":"2024","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.sbi.2026.103221_bib6","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/s41590-018-0304-y","article-title":"Gammadelta TCR ligands: the quest to solve a 500-million-year-old mystery","volume":"20","author":"Willcox","year":"2019","journal-title":"Nat Immunol"},{"key":"10.1016\/j.sbi.2026.103221_bib7","doi-asserted-by":"crossref","first-page":"543","DOI":"10.4049\/jimmunol.2400114","article-title":"The evolving portrait of gammadelta TCR recognition determinants","volume":"213","author":"Sok","year":"2024","journal-title":"J Immunol"},{"key":"10.1016\/j.sbi.2026.103221_bib8","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1084\/jem.20041851","article-title":"Shared reactivity of Vdelta2(neg) gammadelta T cells against cytomegalovirus-infected cells and tumor intestinal epithelial cells","volume":"201","author":"Halary","year":"2005","journal-title":"J Exp Med"},{"key":"10.1016\/j.sbi.2026.103221_bib9","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/j.1365-2249.2007.03388.x","article-title":"Skewed T cell receptor repertoire of Vdelta1(+) gammadelta T lymphocytes after human allogeneic haematopoietic stem cell transplantation and the potential role for Epstein-Barr virus-infected B cells in clonal restriction","volume":"149","author":"Fujishima","year":"2007","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.sbi.2026.103221_bib10","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1126\/science.279.5357.1737","article-title":"Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells","volume":"279","author":"Groh","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103221_bib11","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/ni.3686","article-title":"Human gammadelta T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection","volume":"18","author":"Ravens","year":"2017","journal-title":"Nat Immunol"},{"key":"10.1016\/j.sbi.2026.103221_bib12","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1038\/s41467-024-45449-y","article-title":"Tumor reactive gammadelta T cells contribute to a complete response to PD-1 blockade in a Merkel cell carcinoma patient","volume":"15","author":"Lien","year":"2024","journal-title":"Nat Commun"},{"key":"10.1016\/j.sbi.2026.103221_bib13","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1038\/s43018-022-00376-z","article-title":"A local human Vdelta1 T cell population is associated with survival in nonsmall-cell lung cancer","volume":"3","author":"Wu","year":"2022","journal-title":"Nat Cancer"},{"key":"10.1016\/j.sbi.2026.103221_bib14","doi-asserted-by":"crossref","first-page":"30","DOI":"10.4049\/jimmunol.1300121","article-title":"Cutting edge: CD1d restriction and Th1\/Th2\/Th17 cytokine secretion by human Vdelta3 T cells","volume":"191","author":"Mangan","year":"2013","journal-title":"J Immunol"},{"key":"10.1016\/j.sbi.2026.103221_bib15","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1038\/s41571-022-00722-1","article-title":"The emerging roles of gammadelta T cells in cancer immunotherapy","volume":"20","author":"Mensurado","year":"2023","journal-title":"Nat Rev Clin Oncol"},{"key":"10.1016\/j.sbi.2026.103221_bib16","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/nri797","article-title":"Gammadelta T cells: functional plasticity and heterogeneity","volume":"2","author":"Carding","year":"2002","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.sbi.2026.103221_bib17","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/s41577-020-00452-4","article-title":"Gammadelta T cells in tissue physiology and surveillance","volume":"21","author":"Ribot","year":"2021","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.sbi.2026.103221_bib18","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1016\/j.immuni.2013.11.001","article-title":"Crystal structure of Vdelta1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human gammadelta T cells","volume":"39","author":"Luoma","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.sbi.2026.103221_bib19","doi-asserted-by":"crossref","first-page":"eaav4036","DOI":"10.1126\/sciimmunol.aav4036","article-title":"Generation and molecular recognition of melanoma-associated antigen-specific human gammadelta T cells","volume":"3","author":"Benveniste","year":"2018","journal-title":"Sci Immunol"},{"key":"10.1016\/j.sbi.2026.103221_bib20","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1038\/ni.2713","article-title":"CD1d-lipid antigen recognition by the gammadelta TCR","volume":"14","author":"Uldrich","year":"2013","journal-title":"Nat Immunol"},{"key":"10.1016\/j.sbi.2026.103221_bib21","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1126\/science.aav3900","article-title":"A class of gammadelta T cell receptors recognize the underside of the antigen-presenting molecule MR1","volume":"366","author":"Le Nours","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103221_bib22","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2110288118","article-title":"Recognition of the antigen-presenting molecule MR1 by a Vdelta3(+) gammadelta T cell receptor","volume":"118","author":"Rice","year":"2021","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.sbi.2026.103221_bib23","doi-asserted-by":"crossref","first-page":"3872","DOI":"10.1038\/s41467-022-31443-9","article-title":"Atypical sideways recognition of CD1a by autoreactive gammadelta T cell receptors","volume":"13","author":"Wegrecki","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.sbi.2026.103221_bib24","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1126\/science.1106885","article-title":"Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22","volume":"308","author":"Adams","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103221_bib25","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1016\/j.str.2025.07.006","article-title":"Antibody-like recognition of a gammadelta T cell receptor toward a foreign antigen","volume":"33","author":"Rashleigh","year":"2025","journal-title":"Structure"},{"key":"10.1016\/j.sbi.2026.103221_bib26","doi-asserted-by":"crossref","first-page":"3330","DOI":"10.1038\/s41467-025-58690-w","article-title":"A naturally selected alphabeta T cell receptor binds HLA-DQ2 molecules without co-contacting the presented peptide","volume":"16","author":"Lim","year":"2025","journal-title":"Nat Commun"},{"key":"10.1016\/j.sbi.2026.103221_bib27","doi-asserted-by":"crossref","first-page":"4505","DOI":"10.7150\/jca.57831","article-title":"Prognostic and therapeutic significance of BTN3A proteins in tumors","volume":"12","author":"Chen","year":"2021","journal-title":"J Cancer"},{"key":"10.1016\/j.sbi.2026.103221_bib28","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1126\/science.8146660","article-title":"Stimulation of human gamma delta T cells by nonpeptidic mycobacterial ligands","volume":"264","author":"Constant","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103221_bib29","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1038\/s41586-023-06525-3","article-title":"Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vgamma9Vdelta2 T cells","volume":"621","author":"Yuan","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103221_bib30","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.immuni.2014.03.003","article-title":"The intracellular B30.2 domain of butyrophilin 3A1 binds phosphoantigens to mediate activation of human Vgamma9Vdelta2 T cells","volume":"40","author":"Sandstrom","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.sbi.2026.103221_bib31","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.immuni.2019.02.016","article-title":"A structural change in Butyrophilin upon phosphoantigen binding underlies phosphoantigen-mediated Vgamma9Vdelta2 T cell activation","volume":"50","author":"Yang","year":"2019","journal-title":"Immunity"},{"key":"10.1016\/j.sbi.2026.103221_bib32","doi-asserted-by":"crossref","first-page":"eaay5516","DOI":"10.1126\/science.aay5516","article-title":"Butyrophilin 2A1 is essential for phosphoantigen reactivity by gammadelta T cells","volume":"367","author":"Rigau","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103221_bib33","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.immuni.2020.02.014","article-title":"Butyrophilin-2A1 directly binds germline-encoded regions of the Vgamma9Vdelta2 TCR and is essential for phosphoantigen sensing","volume":"52","author":"Karunakaran","year":"2020","journal-title":"Immunity"},{"key":"10.1016\/j.sbi.2026.103221_bib34","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.chembiol.2014.06.006","article-title":"Synthesis of a phosphoantigen prodrug that potently activates Vgamma9Vdelta2 T-lymphocytes","volume":"21","author":"Hsiao","year":"2014","journal-title":"Chem Biol"},{"key":"10.1016\/j.sbi.2026.103221_bib35","doi-asserted-by":"crossref","first-page":"4697","DOI":"10.1096\/fj.201601370RR","article-title":"The butyrophilin 3A1 intracellular domain undergoes a conformational change involving the juxtamembrane region","volume":"31","author":"Nguyen","year":"2017","journal-title":"FASEB J"},{"key":"10.1016\/j.sbi.2026.103221_bib36","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.1021\/acschembio.7b00694","article-title":"BTN3A1 discriminates gammadelta T cell phosphoantigens from nonantigenic small molecules via a conformational sensor in its B30.2 domain","volume":"12","author":"Salim","year":"2017","journal-title":"ACS Chem Biol"},{"key":"10.1016\/j.sbi.2026.103221_bib37","doi-asserted-by":"crossref","first-page":"E7311","DOI":"10.1073\/pnas.1707547114","article-title":"Phosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on Vgamma9Vdelta2 T cell activation","volume":"114","author":"Gu","year":"2017","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.sbi.2026.103221_bib38","doi-asserted-by":"crossref","first-page":"7617","DOI":"10.1038\/s41467-023-41938-8","article-title":"A distinct topology of BTN3A IgV and B30.2 domains controlled by juxtamembrane regions favors optimal human gammadelta T cell phosphoantigen sensing","volume":"14","author":"Karunakaran","year":"2023","journal-title":"Nat Commun"},{"key":"10.1016\/j.sbi.2026.103221_sref39","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1038\/s41590-024-01892-z","article-title":"Vgamma9Vdelta2 T cells recognize butyrophilin 2A1 and 3A1 heteromers","volume":"25","author":"Fulford","year":"2024","journal-title":"Nat Immunol"},{"key":"10.1016\/j.sbi.2026.103221_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.112321","article-title":"Phosphoantigen sensing combines TCR-dependent recognition of the BTN3A IgV domain and germline interaction with BTN2A1","volume":"42","author":"Willcox","year":"2023","journal-title":"Cell Rep"},{"key":"10.1016\/j.sbi.2026.103221_sref41","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1016\/j.immuni.2025.04.012","article-title":"Phosphoantigen-induced inside-out stabilization of butyrophilin receptor complexes drives dimerization-dependent gammadelta TCR activation","volume":"58","author":"Zhu","year":"2025","journal-title":"Immunity"},{"key":"10.1016\/j.sbi.2026.103221_sref42","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1016\/j.immuni.2025.05.011","article-title":"Structures of butyrophilin multimers reveal a plier-like mechanism for Vgamma9Vdelta2 T cell receptor activation","volume":"58","author":"Zhang","year":"2025","journal-title":"Immunity"},{"key":"10.1016\/j.sbi.2026.103221_bib43","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1126\/science.2955517","article-title":"Structurally divergent human T cell receptor gamma proteins encoded by distinct C gamma genes","volume":"237","author":"Krangel","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103221_bib44","doi-asserted-by":"crossref","first-page":"3817","DOI":"10.1073\/pnas.84.11.3817","article-title":"T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes","volume":"84","author":"Krangel","year":"1987","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.sbi.2026.103221_bib45","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/322145a0","article-title":"Identification of a putative second T-cell receptor","volume":"322","author":"Brenner","year":"1986","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103221_bib46","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/316464a0","article-title":"Two tandemly organized human genes encoding the T-cell gamma constant-region sequences show multiple rearrangement in different T-cell types","volume":"316","author":"Lefranc","year":"1985","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103221_bib47","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.cell.2006.08.044","article-title":"The structure of the zetazeta transmembrane dimer reveals features essential for its assembly with the T cell receptor","volume":"127","author":"Call","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103221_bib48","doi-asserted-by":"crossref","first-page":"7675","DOI":"10.1073\/pnas.0402295101","article-title":"Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3","volume":"101","author":"Kjer-Nielsen","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.sbi.2026.103221_bib49","doi-asserted-by":"crossref","first-page":"16268","DOI":"10.1073\/pnas.0407359101","article-title":"Crystal structure of a human CD3-epsilon\/delta dimer in complex with a UCHT1 single-chain antibody fragment","volume":"101","author":"Arnett","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.sbi.2026.103221_bib50","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/S0092-8674(01)00395-6","article-title":"Mechanisms contributing to T cell receptor signaling and assembly revealed by the solution structure of an ectodomain fragment of the CD3 epsilon gamma heterodimer","volume":"105","author":"Sun","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103221_bib51","doi-asserted-by":"crossref","first-page":"16867","DOI":"10.1073\/pnas.0407576101","article-title":"Solution structure of the CD3epsilondelta ectodomain and comparison with CD3epsilongamma as a basis for modeling T cell receptor topology and signaling","volume":"101","author":"Sun","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.sbi.2026.103221_bib52","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1038\/s41586-019-1537-0","article-title":"Structural basis of assembly of the human T cell receptor-CD3 complex","volume":"573","author":"Dong","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103221_bib53","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1016\/j.molcel.2022.02.017","article-title":"Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility","volume":"82","author":"Chen","year":"2022","journal-title":"Mol Cell"},{"key":"10.1016\/j.sbi.2026.103221_bib54","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/S0092-8674(02)01194-7","article-title":"The organizing principle in the formation of the T cell receptor-CD3 complex","volume":"111","author":"Call","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103221_bib55","doi-asserted-by":"crossref","first-page":"3201","DOI":"10.1016\/j.cell.2022.07.010","article-title":"Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC","volume":"185","author":"Susac","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103221_bib56","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1038\/s41467-023-37532-7","article-title":"Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM","volume":"14","author":"Saotome","year":"2023","journal-title":"Nat Commun"},{"key":"10.1016\/j.sbi.2026.103221_sref57","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/s41586-024-07439-4","article-title":"Structures of human gammadelta T cell receptor-CD3 complex","volume":"630","author":"Xin","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103221_sref58","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1038\/s41586-024-07920-0","article-title":"Structure of a fully assembled gammadelta T cell antigen receptor","volume":"634","author":"Gully","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103221_sref59","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1038\/s41467-024-55467-5","article-title":"Structural characterization of two gammadelta TCR\/CD3 complexes","volume":"16","author":"Hoque","year":"2025","journal-title":"Nat Commun"}],"container-title":["Current Opinion in Structural Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959440X26000035?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959440X26000035?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T16:00:50Z","timestamp":1781539250000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959440X26000035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":59,"alternative-id":["S0959440X26000035"],"URL":"https:\/\/doi.org\/10.1016\/j.sbi.2026.103221","relation":{},"ISSN":["0959-440X"],"issn-type":[{"value":"0959-440X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Structural biology of \u03b3\u03b4 T cell receptors","name":"articletitle","label":"Article Title"},{"value":"Current Opinion in Structural Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sbi.2026.103221","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"103221"}}