{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:58:10Z","timestamp":1790805490052,"version":"4.1.0"},"reference-count":83,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,9,29]],"date-time":"2027-09-29T00:00:00Z","timestamp":1822176000000},"content-version":"am","delay-in-days":302,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000051","name":"National Human Genome Research Institute","doi-asserted-by":"publisher","award":["DP2-HG012442"],"award-info":[{"award-number":["DP2-HG012442"]}],"id":[{"id":"10.13039\/100000051","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["U01DK127421"],"award-info":[{"award-number":["U01DK127421"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R35GM127020"],"award-info":[{"award-number":["R35GM127020"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Opinion in Structural Biology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.sbi.2026.103404","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:54:24Z","timestamp":1790690064000},"page":"103404","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Going through the motions; Chromatin organization and dynamics across scales"],"prefix":"10.1016","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3324-789X","authenticated-orcid":false,"given":"Camille M.","family":"Moore","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Ramani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geeta J.","family":"Narlikar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sbi.2026.103404_bib1","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.molcel.2017.06.018","article-title":"Dynamic organization of chromatin domains revealed by super-resolution live-cell imaging","volume":"67","author":"Nozaki","year":"2017","journal-title":"Mol Cell"},{"key":"10.1016\/j.sbi.2026.103404_bib2","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.molcel.2020.05.036","article-title":"Two-parameter mobility assessments discriminate diverse regulatory factor behaviors in chromatin","volume":"79","author":"Lerner","year":"2020","journal-title":"Mol Cell"},{"key":"10.1016\/j.sbi.2026.103404_sref3","doi-asserted-by":"crossref","first-page":"5282","DOI":"10.1016\/j.cell.2024.07.034","article-title":"Condensate interfacial forces reposition DNA loci and probe chromatin viscoelasticity","volume":"187","author":"Strom","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103404_bib4","series-title":"Elastomer blends and composites","first-page":"171","author":"Gogoi","year":"2022"},{"key":"10.1016\/j.sbi.2026.103404_bib5","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adu8400","article-title":"Replication-dependent histone labeling dissects the physical properties of euchromatin\/heterochromatin in living human cells","volume":"11","author":"Minami","year":"2025","journal-title":"Sci Adv"},{"key":"10.1016\/j.sbi.2026.103404_bib6","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/38444","article-title":"Crystal structure of the nucleosome core particle at 2.8 \u00c5 resolution","volume":"389","author":"Luger","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103404_bib7","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1126\/science.184.4139.868","article-title":"Chromatin structure: a repeating unit of histones and DNA","volume":"184","author":"Kornberg","year":"1974","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103404_bib8","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1038\/nsmb801","article-title":"Nucleosomes facilitate their own invasion","volume":"11","author":"Li","year":"2004","journal-title":"Nat Struct Mol Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib9","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1007\/s10895-007-0218-9","article-title":"Single-pair FRET microscopy reveals mononucleosome dynamics","volume":"17","author":"Koopmans","year":"2007","journal-title":"J Fluoresc"},{"key":"10.1016\/j.sbi.2026.103404_bib10","doi-asserted-by":"crossref","DOI":"10.1126\/science.aaa3761","article-title":"Distortion of histone octamer core promotes nucleosome mobilization by a chromatin remodeler","volume":"355","author":"Sinha","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103404_bib11","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.ceb.2019.02.003","article-title":"Dynamic chromatin organization without the 30-nm fiber","volume":"58","author":"Maeshima","year":"2019","journal-title":"Curr Opin Cell Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib12","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.cell.2019.08.037","article-title":"Organization of chromatin by intrinsic and regulated phase separation","volume":"179","author":"Gibson","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103404_bib13","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2218085120","article-title":"In diverse conditions, intrinsic chromatin condensates have liquid-like material properties","volume":"120","author":"Gibson","year":"2023","journal-title":"P Natl Acad Sci USA"},{"key":"10.1016\/j.sbi.2026.103404_sref14","doi-asserted-by":"crossref","first-page":"eadr0018","DOI":"10.1126\/science.adr0018","article-title":"ATP-dependent remodeling of chromatin condensates reveals distinct mesoscale outcomes","volume":"390","author":"Moore","year":"2025","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103404_bib15","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.cub.2017.12.035","article-title":"A transient rise in free Mg2+ ions released from ATP-Mg hydrolysis contributes to mitotic chromosome condensation","volume":"28","author":"Maeshima","year":"2018","journal-title":"Curr Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib16","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.biocel.2009.07.009","article-title":"Modulation of cellular function by polyamines","volume":"42","author":"Igarashi","year":"2010","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib17","article-title":"Quantitative spatial analysis of chromatin biomolecular condensates using cryoelectron tomography","volume":"122","author":"Zhou","year":"2025"},{"key":"10.1016\/j.sbi.2026.103404_bib18","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1016\/j.celrep.2012.11.008","article-title":"Local nucleosome dynamics facilitate chromatin accessibility in living Mammalian cells","volume":"2","author":"Hihara","year":"2012","journal-title":"Cell Rep"},{"key":"10.1016\/j.sbi.2026.103404_bib19","series-title":"\u201cDas\u201d Heterochromatin der Moose","author":"Heitz","year":"1928"},{"key":"10.1016\/j.sbi.2026.103404_bib20","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1126\/science.1181369","article-title":"Comprehensive mapping of long-range interactions reveals folding principles of the human genome","volume":"326","author":"Lieberman-Aiden","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103404_sref21","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1038\/s41586-025-08971-7","article-title":"Native nucleosomes intrinsically encode genome organization principles","volume":"643","author":"Park","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103404_bib22","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1126\/science.1112178","article-title":"Genome-scale identification of nucleosome positions in S. cerevisiae","volume":"309","author":"Yuan","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103404_bib23","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.cell.2015.05.048","article-title":"Mapping nucleosome resolution chromosome folding in yeast by Micro-C","volume":"162","author":"Hsieh","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103404_bib24","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1146\/annurev-biophys-051013-022819","article-title":"Mechanisms of ATP-dependent chromatin remodeling motors","volume":"45","author":"Zhou","year":"2016","journal-title":"Annu Rev Biophys"},{"key":"10.1016\/j.sbi.2026.103404_sref25","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1038\/s41588-023-01649-8","article-title":"In vitro reconstitution of chromatin domains shows a role for nucleosome positioning in 3D genome organization","volume":"56","author":"Oberbeckmann","year":"2024","journal-title":"Nat Genet"},{"key":"10.1016\/j.sbi.2026.103404_bib26","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.cell.2016.09.045","article-title":"Genomic nucleosome organization reconstituted with pure proteins","volume":"167","author":"Krietenstein","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103404_bib27","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.ydbio.2009.06.012","article-title":"Nucleosome positioning: how is it established, and why does it matter?","volume":"339","author":"Radman-Livaja","year":"2010","journal-title":"Dev Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib28","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.cell.2017.05.004","article-title":"Targeted degradation of CTCF decouples local insulation of chromosome domains from genomic compartmentalization","volume":"169","author":"Nora","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103404_bib29","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/nature22063","article-title":"Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl","volume":"544","author":"Busslinger","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103404_sref30","doi-asserted-by":"crossref","DOI":"10.1126\/science.adv6588","article-title":"Multiscale structure of chromatin condensates explains phase separation and material properties","volume":"390","author":"Zhou","year":"2025","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103404_bib31","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.59404","article-title":"Massively multiplex single-molecule oligonucleosome footprinting","volume":"9","author":"Abdulhay","year":"2020","journal-title":"eLife"},{"key":"10.1016\/j.sbi.2026.103404_bib32","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1038\/s41594-023-01093-6","article-title":"Nucleosome density shapes kilobase-scale regulation by a mammalian chromatin remodeler","volume":"30","author":"Abdulhay","year":"2023","journal-title":"Nat Struct Mol Biol"},{"key":"10.1016\/j.sbi.2026.103404_sref33","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.ads4473","article-title":"HMGB1 deforms nucleosomal DNA to generate a dynamic chromatin environment counteracting the effects of linker histone","volume":"11","author":"Saunders","year":"2025","journal-title":"Sci Adv"},{"key":"10.1016\/j.sbi.2026.103404_bib34","doi-asserted-by":"crossref","DOI":"10.1038\/srep19122","article-title":"A quantitative investigation of linker histone interactions with nucleosomes and chromatin","volume":"6","author":"White","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.sbi.2026.103404_bib35","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1038\/35048610","article-title":"Dynamic binding of histone H1 to chromatin in living cells","volume":"408","author":"Misteli","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103404_bib36","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aec9801","article-title":"Linker histone H1 functions as a liquid-like glue to organize chromatin in living human cells","volume":"12","author":"Shimazoe","year":"2026","journal-title":"Sci. Adv."},{"key":"10.1016\/j.sbi.2026.103404_bib37","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.cell.2015.01.054","article-title":"Chromatin fibers are formed by heterogeneous groups of nucleosomes in vivo","volume":"160","author":"Ricci","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103404_bib38","doi-asserted-by":"crossref","DOI":"10.1126\/science.aag0025","article-title":"ChromEMT: visualizing 3D chromatin structure and compaction in interphase and mitotic cells","volume":"357","author":"Ou","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103404_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmb.2020.11.001","article-title":"Nucleosome clutches are regulated by chromatin internal parameters","volume":"433","author":"Portillo-Ledesma","year":"2021","journal-title":"J Mol Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib40","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1063\/1.1699180","article-title":"A theory of the linear viscoelastic properties of dilute solutions of coiling polymers","volume":"21","author":"Rouse","year":"1953","journal-title":"J Chem Phys"},{"key":"10.1016\/j.sbi.2026.103404_sref41","article-title":"Chromatin dynamics are highly subdiffusive across seven orders of magnitude","author":"Mazzocca","year":"2025","journal-title":"bioRxiv"},{"key":"10.1016\/j.sbi.2026.103404_bib42","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1016\/j.cell.2020.11.027","article-title":"Condensed chromatin behaves like a solid on the mesoscale in vitro and in living cells","volume":"183","author":"Strickfaden","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103404_bib43","doi-asserted-by":"crossref","first-page":"eadf1488","DOI":"10.1126\/sciadv.adf1488","article-title":"Condensed but liquid-like domain organization of active chromatin regions in living human cells","volume":"9","author":"Nozaki","year":"2023","journal-title":"Sci Adv"},{"key":"10.1016\/j.sbi.2026.103404_bib44","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/nature11049","article-title":"Spatial partitioning of the regulatory landscape of the X-inactivation centre","volume":"485","author":"Nora","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103404_bib45","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nature11082","article-title":"Topological domains in mammalian genomes identified by analysis of chromatin interactions","volume":"485","author":"Dixon","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103404_bib46","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1126\/science.aaz3418","article-title":"DNA loop extrusion by human cohesin","volume":"366","author":"Davidson","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103404_bib47","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1080\/19491034.2020.1782024","article-title":"CTCF as a boundary factor for cohesin-mediated loop extrusion: evidence for a multi-step mechanism","volume":"11","author":"Hansen","year":"2020","journal-title":"Nucleus"},{"key":"10.1016\/j.sbi.2026.103404_sref48","doi-asserted-by":"crossref","DOI":"10.1126\/science.adx2202","article-title":"Kinetic organization of the genome revealed by ultraresolution multiscale live imaging","volume":"389","author":"Lee","year":"2025","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103404_bib49","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/336427a0","article-title":"A hit-and-run mechanism for transcriptional activation?","volume":"336","author":"Schaffner","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103404_bib50","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.1016\/j.cell.2024.04.001","article-title":"Direct observation of a condensate effect on super-enhancer controlled gene bursting","volume":"187","author":"Du","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103404_bib51","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/s41580-024-00710-6","article-title":"Enhancer selectivity in space and time: from enhancer\u2013promoter interactions to promoter activation","volume":"25","author":"Yang","year":"2024","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib52","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a040162","article-title":"Mammalian DNA replication timing","volume":"13","author":"Vouzas","year":"2021","journal-title":"Cold Spring Harbor Perspect Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib53","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.cell.2018.05.024","article-title":"Higher-Order inter-chromosomal Hubs shape 3D genome organization in the nucleus","volume":"174","author":"Quinodoz","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103404_bib54","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/s41586-020-03126-2","article-title":"Integrated spatial genomics reveals global architecture of single nuclei","volume":"590","author":"Takei","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103404_bib55","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.ceb.2014.03.001","article-title":"Nucleolus and nuclear periphery: velcro for heterochromatin","volume":"28","author":"Padeken","year":"2014","journal-title":"Curr Opin Cell Biol"},{"key":"10.1016\/j.sbi.2026.103404_sref56","doi-asserted-by":"crossref","DOI":"10.1016\/j.ceb.2023.102313","article-title":"Lamins: the backbone of the nucleocytoskeleton interface","volume":"86","author":"Sobo","year":"2024","journal-title":"Curr Opin Cell Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib57","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/s41580-022-00483-w","article-title":"Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance","volume":"23","author":"Padeken","year":"2022","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib58","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/ng843","article-title":"Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component","volume":"30","author":"Maison","year":"2002","journal-title":"Nat Genet"},{"key":"10.1016\/j.sbi.2026.103404_bib59","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1038\/nature22822","article-title":"Liquid droplet formation by HP1\u03b1 suggests a role for phase separation in heterochromatin","volume":"547","author":"Larson","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103404_bib60","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1016\/j.stemcr.2023.08.004","article-title":"A functional crosstalk between the H3K9 methylation writers and their reader HP1 in safeguarding embryonic stem cell identity","volume":"18","author":"Dong","year":"2023","journal-title":"Stem Cell Rep"},{"key":"10.1016\/j.sbi.2026.103404_bib61","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1126\/science.1078572","article-title":"Maintenance of stable heterochromatin domains by dynamic HP1 binding","volume":"299","author":"Cheutin","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.sbi.2026.103404_bib62","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.64563","article-title":"HP1 proteins compact DNA into mechanically and positionally stable phase separated domains","volume":"10","author":"Keenen","year":"2021","journal-title":"eLife"},{"key":"10.1016\/j.sbi.2026.103404_sref63","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1038\/s41556-024-01547-z","article-title":"Distinct H3K9me3 heterochromatin maintenance dynamics govern different gene programmes and repeats in pluripotent cells","volume":"26","author":"Zhang","year":"2024","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib64","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.celrep.2018.12.020","article-title":"Dynamics of chromatin and transcription during transient depletion of the RSC chromatin remodeling complex","volume":"26","author":"Klein-Brill","year":"2019","journal-title":"Cell Rep"},{"key":"10.1016\/j.sbi.2026.103404_sref65","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.bpj.2024.11.3322","article-title":"Metabolically intact nuclei are fluidized by the activity of the chromatin remodeling motor BRG1","volume":"124","author":"Byfield","year":"2025","journal-title":"Biophys J"},{"key":"10.1016\/j.sbi.2026.103404_bib66","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/ng1046","article-title":"An ACF1\u2013ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin","volume":"32","author":"Collins","year":"2002","journal-title":"Nat Genet"},{"key":"10.1016\/j.sbi.2026.103404_bib67","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1101\/gad.1139604","article-title":"Acf1 confers unique activities to ACF\/CHRAC and promotes the formation rather than disruption of chromatin in vivo","volume":"18","author":"Fyodorov","year":"2004","journal-title":"Genes Dev"},{"key":"10.1016\/j.sbi.2026.103404_bib68","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1101\/gr.182618.114","article-title":"Asymmetric nucleosomes flank promoters in the budding yeast genome","volume":"25","author":"Ramachandran","year":"2015","journal-title":"Genome Res"},{"key":"10.1016\/j.sbi.2026.103404_bib69","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1038\/s41588-024-01767-x","article-title":"Systematic assessment of ISWI subunits shows that NURF creates local accessibility for CTCF","volume":"56","author":"Iurlaro","year":"2024","journal-title":"Nat Genet"},{"key":"10.1016\/j.sbi.2026.103404_bib70","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a039719","article-title":"Essential roles for RNA in shaping nuclear organization","volume":"14","author":"Quinodoz","year":"2022","journal-title":"Cold Spring Harbor Perspect Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib71","doi-asserted-by":"crossref","first-page":"5775","DOI":"10.1016\/j.cell.2021.10.014","article-title":"RNA promotes the formation of spatial compartments in the nucleus","volume":"184","author":"Quinodoz","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103404_bib72","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/nrm.2017.7","article-title":"Biomolecular condensates: organizers of cellular biochemistry","volume":"18","author":"Banani","year":"2017","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib73","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.235093","article-title":"The liquid nucleome \u2013 phase transitions in the nucleus at a glance","volume":"132","author":"Strom","year":"2019","journal-title":"J Cell Sci"},{"key":"10.1016\/j.sbi.2026.103404_bib74","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.molcel.2020.10.038","article-title":"Distinct structures and dynamics of chromatosomes with different human linker histone isoforms","volume":"81","author":"Zhou","year":"2021","journal-title":"Mol Cell"},{"key":"10.1016\/j.sbi.2026.103404_bib75","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2020105740","article-title":"RNA polymerase II speed: a key player in controlling and adapting transcriptome composition","volume":"40","author":"Muniz","year":"2021","journal-title":"EMBO J"},{"key":"10.1016\/j.sbi.2026.103404_bib76","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/s41586-018-0261-5","article-title":"High speed of fork progression induces DNA replication stress and genomic instability","volume":"559","author":"Maya-Mendoza","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.sbi.2026.103404_bib77","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1038\/s41592-024-02308-4","article-title":"Quantifying DNA replication speeds in single cells by scEdU-seq","volume":"21","author":"van den Berg","year":"2024","journal-title":"Nat Methods"},{"key":"10.1016\/j.sbi.2026.103404_bib78","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1016\/j.cub.2006.06.068","article-title":"Live-cell imaging reveals a stable cohesin-chromatin interaction after but not before DNA replication","volume":"16","author":"Gerlich","year":"2006","journal-title":"Curr Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib79","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.cell.2006.09.040","article-title":"Wapl controls the dynamic association of cohesin with chromatin","volume":"127","author":"Kueng","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.sbi.2026.103404_bib80","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.tig.2023.11.003","article-title":"Time will tell: comparing timescales to gain insight into transcriptional bursting","volume":"40","author":"Meeussen","year":"2024","journal-title":"Trends Genet"},{"key":"10.1016\/j.sbi.2026.103404_bib81","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1083\/jcb.153.7.1341","article-title":"Kinetics of core histones in living human cells","volume":"153","author":"Kimura","year":"2001","journal-title":"J Cell Biol"},{"key":"10.1016\/j.sbi.2026.103404_bib82","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1021\/bi00455a019","article-title":"In vivo studies on the dynamics of histone-DNA interaction: evidence for nucleosome dissolution during replication and transcription and a low level of dissolution independent of both","volume":"29","author":"Jackson","year":"1990","journal-title":"Biochemistry"},{"key":"10.1016\/j.sbi.2026.103404_bib83","doi-asserted-by":"crossref","first-page":"3381","DOI":"10.1016\/j.molcel.2024.07.030","article-title":"Navigating the complexity of polycomb repression: enzymatic cores and regulatory modules","volume":"84","author":"Tamburri","year":"2024","journal-title":"Mol Cell"}],"container-title":["Current Opinion in Structural Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959440X26001867?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959440X26001867?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:15:02Z","timestamp":1790802902000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959440X26001867"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":83,"alternative-id":["S0959440X26001867"],"URL":"https:\/\/doi.org\/10.1016\/j.sbi.2026.103404","relation":{},"ISSN":["0959-440X"],"issn-type":[{"value":"0959-440X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Going through the motions; Chromatin organization and dynamics across scales","name":"articletitle","label":"Article Title"},{"value":"Current Opinion in Structural Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sbi.2026.103404","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103404"}}