{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T09:24:51Z","timestamp":1788513891910,"version":"build-2803163510"},"reference-count":18,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5F31 MH12803-03"],"award-info":[{"award-number":["5F31 MH12803-03"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["5KO5MH00619"],"award-info":[{"award-number":["5KO5MH00619"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH37692"],"award-info":[{"award-number":["MH37692"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Schizophrenia Research"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.schres.2005.08.008","type":"journal-article","created":{"date-parts":[[2005,10,21]],"date-time":"2005-10-21T07:13:45Z","timestamp":1129878825000},"page":"253-260","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Premorbid childhood ocular alignment abnormalities and adult schizophrenia-spectrum disorder"],"prefix":"10.1016","volume":"81","author":[{"given":"Jason","family":"Schiffman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin A.","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentaro","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels","family":"Michelsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger J.","family":"Sorensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morton","family":"Ekstrom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kylie A.","family":"Abe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward P.","family":"Chronicle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarnoff A.","family":"Mednick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.schres.2005.08.008_bib1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0920-9964(02)00438-3","article-title":"Antisaccade performance is abnormal in schizophrenia patients but not in their biological relatives","volume":"63","author":"Brownstein","year":"2003","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.schres.2005.08.008_bib2","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1037\/0033-2909.108.1.77","article-title":"Is eye movement dysfunction a biological marker for schizophrenia? A methodological review","volume":"108","author":"Clementz","year":"1990","journal-title":"Psychol. Bull."},{"key":"10.1016\/j.schres.2005.08.008_bib3","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0022-3956(03)00105-5","article-title":"Smooth pursuit and antisaccade eye movements in siblings discordant for schizophrenia","volume":"38","author":"Ettinger","year":"2004","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.schres.2005.08.008_bib4","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1176\/jnp.4.4.422","article-title":"Visual perceptual dysfunction in patients with schizophrenic and affective disorders versus control subjects","volume":"4","author":"Flach","year":"1992","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"key":"10.1016\/j.schres.2005.08.008_bib5","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1152\/physrev.2000.80.3.953","article-title":"Role of the basal ganglia in the control of purposive saccadic eye movements","volume":"80","author":"Hikosaka","year":"2000","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.schres.2005.08.008_bib6","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1017\/S0033291798006722","article-title":"Smooth pursuit and saccadic abnormalities in first-episode schizophrenia","volume":"28","author":"Hutton","year":"1998","journal-title":"Psychol. Med."},{"key":"10.1016\/j.schres.2005.08.008_bib7","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0165-1781(01)00227-X","article-title":"Poor performance in smooth pursuit and antisaccadic eye-movement tasks in healthy siblings of patients with schizophrenia","volume":"101","author":"Karoumi","year":"2001","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.schres.2005.08.008_bib8","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1176\/appi.ajp.160.4.696","article-title":"Deficits in gain of smooth pursuit eye movements in schizophrenia and affective disorder patients and their unaffected relatives","volume":"160","author":"Kathmann","year":"2003","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2005.08.008_bib9","series-title":"The Neurology of Eye Movements","author":"Leigh","year":"1999"},{"key":"10.1016\/j.schres.2005.08.008_bib10","first-page":"S103","article-title":"Perinatal conditions and infant development in children with schizophrenic parents","volume":"18","author":"Mednick","year":"1971","journal-title":"Soc. Biol."},{"key":"10.1016\/j.schres.2005.08.008_bib11","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0165-1781(96)02975-7","article-title":"Eye-tracking dysfunction in offspring from the New York high-risk project: diagnostic specificity and the role of attention","volume":"66","author":"Rosenberg","year":"1997","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.schres.2005.08.008_bib12","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1097\/00004583-199607000-00022","article-title":"Early expression of smooth-pursuit eye movement abnormalities in children of schizophrenic parents","volume":"35","author":"Ross","year":"1996","journal-title":"J. Am. Acad. Child Adolesc. Psych."},{"key":"10.1016\/j.schres.2005.08.008_bib13","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1176\/appi.ajp.159.2.238","article-title":"Minor physical anomalies and schizophrenia spectrum disorders: a prospective investigation","volume":"159","author":"Schiffman","year":"2002","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2005.08.008_bib14","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0920-9964(97)00011-X","article-title":"Visually-guided saccadic eye movements in adolescents at genetic risk for schizophrenia","volume":"25","author":"Schreiber","year":"1997","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.schres.2005.08.008_bib15","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1093\/hmg\/ddh047","article-title":"Association between schizophrenia with ocular misalignment and polyalanine length variation in PMX2B","volume":"13","author":"Toyota","year":"2004","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.schres.2005.08.008_bib16","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1176\/appi.ajp.161.2.315","article-title":"Neurobiology of smooth pursuit eye movement deficits in schizophrenia: an fMRI study","volume":"161","author":"Tregellas","year":"2004","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2005.08.008_bib17","series-title":"Exceptional Infant: Studies in Abnormalities","article-title":"Minor physical anomalies and hyperactive behavior in young children","author":"Waldrop","year":"1971"},{"key":"10.1016\/j.schres.2005.08.008_bib18","series-title":"Babies: Human Development During the First Year","author":"Zachau-Christiansen","year":"1975"}],"container-title":["Schizophrenia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996405003737?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996405003737?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T01:00:30Z","timestamp":1778547630000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920996405003737"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":18,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S0920996405003737"],"URL":"https:\/\/doi.org\/10.1016\/j.schres.2005.08.008","relation":{},"ISSN":["0920-9964"],"issn-type":[{"value":"0920-9964","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Premorbid childhood ocular alignment abnormalities and adult schizophrenia-spectrum disorder","name":"articletitle","label":"Article Title"},{"value":"Schizophrenia Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.schres.2005.08.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}