{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T19:05:38Z","timestamp":1773083138504,"version":"3.50.1"},"reference-count":80,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Schizophrenia Research"],"published-print":{"date-parts":[[2009,9]]},"DOI":"10.1016\/j.schres.2009.06.006","type":"journal-article","created":{"date-parts":[[2009,7,2]],"date-time":"2009-07-02T09:48:17Z","timestamp":1246528097000},"page":"308-321","source":"Crossref","is-referenced-by-count":19,"title":["Serotonergic hyperinnervation and effective serotonin blockade in an FGF receptor developmental model of psychosis"],"prefix":"10.1016","volume":"113","author":[{"given":"Ilona","family":"Klejbor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron","family":"Kucinski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott R.","family":"Wersinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Corso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan H.","family":"Spodnik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerzy","family":"Dziewi\u0105tkowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janusz","family":"Mory\u015b","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renae A.","family":"Hesse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenner C.","family":"Rice","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Miletich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa K.","family":"Stachowiak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michal K.","family":"Stachowiak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.schres.2009.06.006_bib1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1192\/bjp.168.1.57","article-title":"Enhancement of the prolactin response to d-fenfluramine in drug-naive schizophrenic patients","volume":"168","author":"Abel","year":"1996","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib2","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.neubiorev.2004.05.001","article-title":"The somatodendritic release of dopamine in the ventral tegmental area and its regulation by afferent transmitter systems","volume":"28","author":"Adell","year":"2004","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.schres.2009.06.006_bib3","first-page":"971","article-title":"Smooth pursuit eye movements, clinical symptoms, CSF metabolites, and skin conductance habituation in schizophrenic patients","volume":"18","author":"Bartfai","year":"1983","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib4","doi-asserted-by":"crossref","first-page":"11539","DOI":"10.1073\/pnas.0504926102","article-title":"Organically modified silica nanoparticles: a nonviral vector for in vivo gene delivery and expression in the brain","volume":"102","author":"Bharali","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.schres.2009.06.006_bib5","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1124\/jpet.104.066365","article-title":"Serotonin 5-HT2A receptors underlie increased motor behaviors induced in dopamine-depleted rats by intrastriatal 5-HT2A\/2C agonism","volume":"310","author":"Bishop","year":"2004","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.schres.2009.06.006_bib6","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.ydbio.2006.11.008","article-title":"Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain","volume":"303","author":"Blak","year":"2007","journal-title":"Dev. Biol."},{"key":"10.1016\/j.schres.2009.06.006_bib7","first-page":"951","article-title":"A morphometric study of the dopamine-containing cell groups in the mesencephalon of normals, Parkinson patients, and schizophrenics","volume":"18","author":"Bogerts","year":"1983","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib8","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1037\/0735-7044.101.6.806","article-title":"Effect of dopamine-depleting brain lesions in rat pups: role of striatal serotonergic neurons in behavior","volume":"101","author":"Bruno","year":"1987","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.schres.2009.06.006_bib9","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/S0166-2236(99)01410-1","article-title":"Paracrine neurotransmission in the CNS: involvement of 5-HT","volume":"22","author":"Bunin","year":"1999","journal-title":"Trends Neurosci."},{"issue":"Suppl 1","key":"10.1016\/j.schres.2009.06.006_bib10","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1055\/s-2006-931483","article-title":"The neurochemical circuitry of schizophrenia","volume":"39","author":"Carlsson","year":"2006","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib11","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/(SICI)1096-9861(19990628)409:2<187::AID-CNE2>3.0.CO;2-P","article-title":"Cellular and subcellular distribution of the serotonin 5-HT2A receptor in the central nervous system of adult rat","volume":"409","author":"Cornea-Hebert","year":"1999","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.schres.2009.06.006_bib12","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1126\/science.1150605","article-title":"BOLD responses reflecting dopaminergic signals in the human ventral tegmental area","volume":"319","author":"D'Ardenne","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.schres.2009.06.006_bib13","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/ajmg.b.10008","article-title":"Association study between CAG trinucleotide repeats in the PCQAP gene (PC2 glutamine\/Q-rich-associated protein) and schizophrenia","volume":"116B","author":"De Luca","year":"2003","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"10.1016\/j.schres.2009.06.006_bib14","first-page":"123","article-title":"M-100907 (Aventis)","volume":"2","author":"de Paulis","year":"2001","journal-title":"Curr. Opin. Investig. Drugs"},{"key":"10.1016\/j.schres.2009.06.006_bib15","doi-asserted-by":"crossref","first-page":"4282","DOI":"10.1523\/JNEUROSCI.17-11-04282.1997","article-title":"Selective expression of dopamine D3 receptor mRNA in proliferative zones during embryonic development of the rat brain","volume":"17","author":"Diaz","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.schres.2009.06.006_bib16","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1091\/mbc.E08-06-0600","article-title":"Fibroblast growth factor receptor-1 (FGFR1) nuclear dynamics reveal a novel mechanism in transcription control","volume":"20","author":"Dunham-Ems","year":"2009","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.schres.2009.06.006_bib17","doi-asserted-by":"crossref","first-page":"28451","DOI":"10.1074\/jbc.M504400200","article-title":"Control of CREB-binding protein signaling by nuclear fibroblast growth factor receptor-1: a novel mechanism of gene regulation","volume":"280","author":"Fang","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.schres.2009.06.006_bib18","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/0306-4522(77)90120-8","article-title":"An anatomical and electrophysiological investigation of the serotonergic projection from the dorsal raphenucleus to the substantia nigra in the rat","volume":"2","author":"Fibiger","year":"1977","journal-title":"Neuroscience"},{"key":"10.1016\/j.schres.2009.06.006_bib19","doi-asserted-by":"crossref","first-page":"5725","DOI":"10.1523\/JNEUROSCI.14-10-05725.1994","article-title":"Otx1 and Otx2 define layers and regions in developing cerebral cortex and cerebellum","volume":"14","author":"Frantz","year":"1994","journal-title":"J. Neurosci."},{"key":"10.1016\/j.schres.2009.06.006_bib20","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.brainresbull.2006.04.008","article-title":"Hippocampal FGF-2 and FGFR1 mRNA expression in major depression, schizophrenia and bipolar disorder","volume":"70","author":"Gaughran","year":"2006","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.schres.2009.06.006_bib21","series-title":"Neuropsychopharmacology: The Fifth Generation of Progress","first-page":"689","article-title":"Animal models relevant to schizophrenia disorders","author":"Geyer","year":"2002"},{"key":"10.1016\/j.schres.2009.06.006_bib22","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/sj.mp.4002062","article-title":"The pipeline and future of drug development in schizophrenia","volume":"12","author":"Gray","year":"2007","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib23","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.brainresrev.2006.12.001","article-title":"The physiological and pharmacological role of basic fibroblast growth factor in the dopaminergic nigrostriatal system","volume":"54","author":"Grothe","year":"2007","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.schres.2009.06.006_bib24","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0169-328X(97)00322-7","article-title":"Localization of 5-HT2A receptor in rat cerebral cortex and olfactory system revealed by immunohistochemistry using two antibodies raised in rabbit and chicken","volume":"54","author":"Hamada","year":"1998","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.schres.2009.06.006_bib25","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0006-8993(87)90207-1","article-title":"Differential effects of acute clozapine and haloperidol on the activity of ventral tegmental (A10) and nigrostriatal (A9) dopamine neurons","volume":"415","author":"Hand","year":"1987","journal-title":"Brain Res."},{"key":"10.1016\/j.schres.2009.06.006_bib26","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/BF01276538","article-title":"Evidence for biochemical heterogeneity in schizophrenia: a multivariate study of monoaminergic indices in human post-mortal brain tissue","volume":"98","author":"Hansson","year":"1994","journal-title":"J. Neural. Transm. Gen. Sect."},{"issue":"Pt 4","key":"10.1016\/j.schres.2009.06.006_bib27","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1093\/brain\/122.4.593","article-title":"The neuropathology of schizophrenia. A critical review of the data and their interpretation","volume":"122","author":"Harrison","year":"1999","journal-title":"Brain"},{"key":"10.1016\/j.schres.2009.06.006_bib28","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1097\/WNR.0b013e3282fd1270","article-title":"Induction of cell migration of neural progenitor cells in vitro by alpha-1 adrenergic receptor and dopamine D1 receptor stimulation","volume":"19","author":"Hiramoto","year":"2008","journal-title":"NeuroReport"},{"key":"10.1016\/j.schres.2009.06.006_bib29","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/S0006-8993(99)02237-4","article-title":"Human midbrain dopamine neurons express serotonin 2A receptor: an immunohistochemical demonstration","volume":"853","author":"Ikemoto","year":"2000","journal-title":"Brain Res."},{"key":"10.1016\/j.schres.2009.06.006_bib30","first-page":"189","article-title":"Dopamine-related neuronal structures in schizophrenia: histochemical study using post-mortem brains","volume":"9","author":"Ikemoto","year":"2008","journal-title":"World J. Biol. Psychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib31","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1159\/000054940","article-title":"Differences in substantia nigra echogenicity of nosological subtypes within the schizophrenic spectrum. A preliminary transcranial ultrasound study","volume":"44","author":"Jabs","year":"2001","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.schres.2009.06.006_bib32","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ydbio.2006.05.002","article-title":"FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region","volume":"297","author":"Jukkola","year":"2006","journal-title":"Dev. Biol."},{"key":"10.1016\/j.schres.2009.06.006_bib33","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/S0022-3565(25)13049-8","article-title":"Serotonergic afferent regulation of the basic physiology and pharmacological responsiveness of nigrostriatal dopamine neurons","volume":"253","author":"Kelland","year":"1990","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.schres.2009.06.006_bib34","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.neuron.2006.01.023","article-title":"Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning","volume":"49","author":"Kellendonk","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.schres.2009.06.006_bib35","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1111\/j.1471-4159.2006.03754.x","article-title":"Fibroblast growth factor receptor signaling affects development and function of dopamine neurons \u2013 inhibition results in a schizophrenia-like syndrome in transgenic mice","volume":"97","author":"Klejbor","year":"2006","journal-title":"J. Neurochem."},{"key":"10.1016\/j.schres.2009.06.006_bib36","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/BF02465329","article-title":"Synaptic contacts in schizophrenia: studies using immunocytochemical identification of dopaminergic neurons","volume":"29","author":"Kolomeets","year":"1999","journal-title":"Neurosci. Behav. Physiol."},{"key":"10.1016\/j.schres.2009.06.006_bib37","series-title":"Classification of Endogenous Psychoses and Their Differentiated Etiology","year":"1999"},{"key":"10.1016\/j.schres.2009.06.006_bib38","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/S0006-3223(98)00187-5","article-title":"Serotonergic basis of antipsychotic drug effects in schizophrenia.","volume":"44","author":"Lieberman","year":"1998","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib39","series-title":"Psychopharmacology: the third generation of progress","first-page":"715","article-title":"The dopamine hypothesis of schizophrenia","author":"Losonczy","year":"1987"},{"key":"10.1016\/j.schres.2009.06.006_bib40","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1083\/jcb.134.2.529","article-title":"Nuclear translocation of fibroblast growth factor (FGF) receptors in response to FGF-2","volume":"134","author":"Maher","year":"1996","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.schres.2009.06.006_bib41","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0306-9877(84)90122-1","article-title":"Influenza and schizophrenia: a possible connection with the substantia nigra","volume":"15","author":"Maurizi","year":"1984","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.schres.2009.06.006_bib42","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.pnpbp.2003.09.010","article-title":"Serotonin receptors: their key role in drugs to treat schizophrenia","volume":"27","author":"Meltzer","year":"2003","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib43","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/nn804","article-title":"Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia","volume":"5","author":"Meyer-Lindenberg","year":"2002","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.schres.2009.06.006_bib44","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1126\/science.1112915","article-title":"DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling","volume":"310","author":"Millar","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.schres.2009.06.006_bib45","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/S0306-4522(96)00452-6","article-title":"Quantitative and morphometric data indicate precise cellular interactions between serotonin terminals and postsynaptic targets in rat substantia nigra","volume":"76","author":"Moukhles","year":"1997","journal-title":"Neuroscience"},{"key":"10.1016\/j.schres.2009.06.006_bib46","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.molbrainres.2003.11.004","article-title":"Expression of the ionotropic glutamate receptor subunits and NMDA receptor-associated intracellular proteins in the substantia nigra in schizophrenia","volume":"121","author":"Mueller","year":"2004","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.schres.2009.06.006_bib47","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1002\/jcb.10476","article-title":"Nuclear trafficking of FGFR1: a role for the transmembrane domain","volume":"88","author":"Myers","year":"2003","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.schres.2009.06.006_bib48","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/sj.mp.4002066","article-title":"Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles","volume":"13","author":"Nasrallah","year":"2008","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib49","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/mp.2008.108","article-title":"Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2","volume":"14","author":"O'Donovan","year":"2009","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib50","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2174\/1568007043337508","article-title":"AMPA receptor potentiators for the treatment of CNS disorders","volume":"3","author":"O'Neill","year":"2004","journal-title":"Curr. Drug Targets CNS Neurol. Disord."},{"key":"10.1016\/j.schres.2009.06.006_bib51","doi-asserted-by":"crossref","first-page":"2840","DOI":"10.1523\/JNEUROSCI.23-07-02840.2003","article-title":"Dopamine modulates cell cycle in the lateral ganglionic eminence","volume":"23","author":"Ohtani","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.schres.2009.06.006_bib52","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1046\/j.0953-816x.2001.01459.x","article-title":"Fibroblast growth factor-2 is selectively modulated in the rat brain by E-5842, a preferential sigma-1 receptor ligand and putative atypical antipsychotic","volume":"13","author":"Ovalle","year":"2001","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.schres.2009.06.006_bib53","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1080\/10673220127883","article-title":"Schizophrenia in late life: findings challenge traditional concepts","volume":"9","author":"Palmer","year":"2001","journal-title":"Harv. Rev. Psychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib54","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/j.biopsych.2004.02.005","article-title":"The origin of schizophrenia: genetic thesis, epigenetic antithesis, and resolving synthesis","volume":"55","author":"Petronis","year":"2004","journal-title":"Biol. Psychiatry"},{"issue":"Suppl B","key":"10.1016\/j.schres.2009.06.006_bib55","first-page":"129","article-title":"Predictors of clozapine response in schizophrenia","volume":"55","author":"Pickar","year":"1994","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib56","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/S0896-6273(02)00824-3","article-title":"FGFR1 is required for the development of the auditory sensory epithelium","volume":"35","author":"Pirvola","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.schres.2009.06.006_bib57","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1159\/000082140","article-title":"Influence of dopamine on precursor cell proliferation and differentiation in the embryonic mouse telencephalon","volume":"26","author":"Popolo","year":"2004","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.schres.2009.06.006_bib58","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.4088\/JCP.v66n1216","article-title":"Open-label risperidone for Asperger's disorder: negative symptom spectrum response","volume":"66","author":"Rausch","year":"2005","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib59","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1083\/jcb.152.6.1307","article-title":"Importin beta-mediated nuclear import of fibroblast growth factor receptor: role in cell proliferation","volume":"152","author":"Reilly","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.schres.2009.06.006_bib60","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/S0306-4522(98)00624-1","article-title":"Serotonin hyperinnervation in the adult rat ventral mesencephalon following unilateral transection of the medial forebrain bundle. Correlation with reactive microglial and astroglial populations","volume":"91","author":"Revuelta","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.schres.2009.06.006_bib61","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0022-3999(71)90051-1","article-title":"The content of 5-hydroxyindoleacetic acid and homovanillic acid in the cerebrospinal fluid of patients with acute schizophrenia","volume":"15","author":"Rimon","year":"1971","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.schres.2009.06.006_bib62","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1046\/j.1460-9568.2003.02949.x","article-title":"Elimination of serotonergic cells induces a marked increase in generation of dopaminergic neurons from mesencephalic precursors","volume":"18","author":"Rodriguez-Pallares","year":"2003","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.schres.2009.06.006_bib63","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0896-6273(00)80264-0","article-title":"Expression of a dominant negative FGF receptor inhibits axonal growth and FGF receptor phosphorylation stimulated by CAMs","volume":"18","author":"Saffell","year":"1997","journal-title":"Neuron"},{"issue":"Suppl 2","key":"10.1016\/j.schres.2009.06.006_bib64","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/00004850-199311002-00004","article-title":"Contribution of serotonin neurotoxins to understanding psychiatric disorders: the role of 5-HT2 receptors in schizophrenia and antipsychotic activity","volume":"8","author":"Schmidt","year":"1993","journal-title":"Int. Clin. Psychopharmacol."},{"key":"10.1016\/j.schres.2009.06.006_bib65","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.schres.2004.03.001","article-title":"Schizophrenia, epigenetics and ligand-activated nuclear receptors: a framework for chromatin therapeutics","volume":"72","author":"Sharma","year":"2005","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.schres.2009.06.006_bib66","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1523\/JNEUROSCI.5285-03.2004","article-title":"Loss of glutamatergic pyramidal neurons in frontal and temporal cortex resulting from attenuation of FGFR1 signaling is associated with spontaneous hyperactivity in mice","volume":"24","author":"Shin","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.schres.2009.06.006_bib67","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/S0022-3565(25)38366-7","article-title":"Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies","volume":"266","author":"Sorensen","year":"1993","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.schres.2009.06.006_bib68","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1091\/mbc.7.8.1299","article-title":"Nuclear accumulation of fibroblast growth factor receptors is regulated by multiple signals in adrenal medullary cells","volume":"7","author":"Stachowiak","year":"1996","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.schres.2009.06.006_bib69","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1046\/j.1471-4159.2003.01624.x","article-title":"cAMP-induced differentiation of human neuronal progenitor cells is mediated by nuclear fibroblast growth factor receptor-1 (FGFR1)","volume":"84","author":"Stachowiak","year":"2003","journal-title":"J. Neurochem."},{"key":"10.1016\/j.schres.2009.06.006_bib70","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1089\/dna.2007.0664","article-title":"Integrative nuclear signaling in cell development\u2014a role for FGF receptor-1","volume":"26","author":"Stachowiak","year":"2007","journal-title":"DNA Cell Biol."},{"key":"10.1016\/j.schres.2009.06.006_bib71","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1039\/b902617g","article-title":"Targeting novel integrative nuclear FGFR1 signaling by nanoparticle-mediated gene transfer stimulates neurogenesis in adult brain","volume":"1","author":"Stachowiak","year":"2009","journal-title":"Integr. Biol."},{"key":"10.1016\/j.schres.2009.06.006_bib72","article-title":"Fibroblast growth factors in schizophrenia","author":"Terwisscha van Scheltinga","year":"2009","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.schres.2009.06.006_bib73","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1093\/oxfordjournals.schbul.a007139","article-title":"Developmental pathology, dopamine, and stress: a model for the age of onset of schizophrenia symptoms","volume":"30","author":"Thompson","year":"2004","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.schres.2009.06.006_bib74","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/BF01254928","article-title":"Dopamine metabolism increases in post-mortem schizophrenic basal ganglia","volume":"54","author":"Toru","year":"1982","journal-title":"J. Neural. Transm."},{"key":"10.1016\/j.schres.2009.06.006_bib75","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/BF00442004","article-title":"Ritanserin, a 5-HT2 receptor antagonist, activates midbrain dopamine neurons by blocking serotonergic inhibition","volume":"98","author":"Ugedo","year":"1989","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.schres.2009.06.006_bib76","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/6350","article-title":"Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis","volume":"2","author":"Vaccarino","year":"1999","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.schres.2009.06.006_bib77","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0006-8993(80)90250-4","article-title":"Dorsal raphe cells with collateral projections to the caudate-putamen and substantia nigra: a fluorescent retrograde double labeling study in the rat","volume":"186","author":"van der Kooy","year":"1980","journal-title":"Brain Res."},{"key":"10.1016\/j.schres.2009.06.006_bib78","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1001\/archpsyc.1987.01800190080012","article-title":"Implications of normal brain development for the pathogenesis of schizophrenia","volume":"44","author":"Weinberger","year":"1987","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.schres.2009.06.006_bib79","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1002\/ar.1092310411","article-title":"Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator","volume":"231","author":"West","year":"1991","journal-title":"Anat. Rec."},{"key":"10.1016\/j.schres.2009.06.006_bib80","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.4088\/JCP.v67n0712","article-title":"Comparison of quetiapine and risperidone in the treatment of schizophrenia: a randomized, double-blind, flexible-dose, 8-week study","volume":"67","author":"Zhong","year":"2006","journal-title":"J. Clin. Psychiatry"}],"container-title":["Schizophrenia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996409002758?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996409002758?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T16:24:56Z","timestamp":1739204696000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920996409002758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9]]},"references-count":80,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["S0920996409002758"],"URL":"https:\/\/doi.org\/10.1016\/j.schres.2009.06.006","relation":{},"ISSN":["0920-9964"],"issn-type":[{"value":"0920-9964","type":"print"}],"subject":[],"published":{"date-parts":[[2009,9]]}}}