{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:12:35Z","timestamp":1792084355642,"version":"4.4.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["schres-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Schizophrenia Research"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1016\/j.schres.2013.12.015","type":"journal-article","created":{"date-parts":[[2014,1,15]],"date-time":"2014-01-15T10:00:24Z","timestamp":1389780024000},"page":"339-343","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":73,"title":["Hippocampal and orbital inferior frontal gray matter volume abnormalities and cognitive deficit in treatment-naive, first-episode patients with schizophrenia"],"prefix":"10.1016","volume":"152","author":[{"given":"Xiaofeng","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoduo","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maorong","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yidong","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huafu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingping","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.schres.2013.12.015_bb0005","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1006\/nimg.2001.1046","article-title":"A developmental fMRI study of the Stroop color-word task","volume":"16","author":"Adleman","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.schres.2013.12.015_bb0010","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0920-9964(03)00002-1","article-title":"MRI-morphometric changes in first-episode schizophrenic patients at 14months follow-up","volume":"67","author":"Bachmann","year":"2004","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.schres.2013.12.015_bb0015","doi-asserted-by":"crossref","first-page":"3855","DOI":"10.1162\/jocn_a_00066","article-title":"Working memory and the hippocampus","volume":"23","author":"Baddeley","year":"2011","journal-title":"J. Cogn. Neurosci."},{"key":"10.1016\/j.schres.2013.12.015_bb7000","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1038\/sj.npp.1301673","article-title":"Prefrontal dysfunction in first-degree relatives of schizophrenia patients during a Stroop task","volume":"33","author":"Becker","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.schres.2013.12.015_bb0020","series-title":"Brief Visuospatial Memory Test\u2014Revised (BVMT-R): Professional Manual","author":"Benedict","year":"1997"},{"key":"10.1016\/j.schres.2013.12.015_bb0030","series-title":"Multilingual Aphasia Examination Manual (Revised)","author":"Benton","year":"1978"},{"key":"10.1016\/j.schres.2013.12.015_bb0035","doi-asserted-by":"crossref","first-page":"9032","DOI":"10.1523\/JNEUROSCI.0702-11.2011","article-title":"Constructing realistic engrams: poststimulus activity of hippocampus and dorsal striatum predicts subsequent episodic memory","volume":"31","author":"Ben-Yakov","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.schres.2013.12.015_bb0040","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1136\/jnnp-2012-303054","article-title":"Verbal memory is associated with structural hippocampal changes in newly diagnosed Parkinson's disease","volume":"84","author":"Beyer","year":"2013","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.schres.2013.12.015_bb0045","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1097\/JCP.0b013e31820e3f58","article-title":"Brain volume changes after withdrawal of atypical antipsychotics in patients with first-episode schizophrenia","volume":"31","author":"Boonstra","year":"2011","journal-title":"J. Clin. Psychopharmacol."},{"key":"10.1016\/j.schres.2013.12.015_bb0025","series-title":"Hopkins Verbal Learning Test\u2014Revised Professional Manual","author":"Brandt","year":"2001"},{"key":"10.1016\/j.schres.2013.12.015_bb0060","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.biopsycho.2012.01.008","article-title":"Structure\u2013function associations in hippocampus in bipolar disorder","volume":"90","author":"Chepenik","year":"2012","journal-title":"Biol. Psychol."},{"key":"10.1016\/j.schres.2013.12.015_bb0065","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.schres.2006.09.009","article-title":"Cerebral grey, white matter and CSF in never-medicated, first-episode schizophrenia","volume":"89","author":"Chua","year":"2007","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.schres.2013.12.015_bb0070","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.schres.2009.09.009","article-title":"Grey and white matter abnormalities are associated with impaired spatial working memory ability in first-episode schizophrenia","volume":"115","author":"Cocchi","year":"2009","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.schres.2013.12.015_bb0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1615\/CritRevNeurobiol.v14.i1.10","article-title":"Cognitive impairment in schizophrenia is the core of the disorder","volume":"14","author":"Elvevag","year":"2000","journal-title":"Crit. Rev. Neurobiol."},{"issue":"2","key":"10.1016\/j.schres.2013.12.015_bb0050","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1176\/jnp.2008.20.2.227","article-title":"Sex-dependent hippocampal volume reductions in schizophrenia relate to episodic memory deficits","volume":"20","author":"Exner","year":"2008","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"key":"10.1016\/j.schres.2013.12.015_bb0080","series-title":"Structured Clinical Interview for DSM-IV Axis I Disorders, Clinician Version (SCID-CV)","author":"First","year":"1996"},{"key":"10.1016\/j.schres.2013.12.015_bb0085","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.biopsych.2008.03.031","article-title":"Meta-analysis of gray matter anomalies in schizophrenia: application of anatomic likelihood estimation and network analysis","volume":"64","author":"Glahn","year":"2008","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.schres.2013.12.015_bb0090","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1176\/appi.ajp.159.8.1395","article-title":"Cognitive correlates of job tenure among patients with severe mental illness","volume":"159","author":"Gold","year":"2002","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2013.12.015_bb0055","series-title":"Stroop Color and Word Test: A Manual for Clinical Experimental Uses","first-page":"1","author":"Golden","year":"1978"},{"key":"10.1016\/j.schres.2013.12.015_bb0095","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s00429-012-0391-8","article-title":"Structure\u2013function relationship of working memory activity with hippocampal and prefrontal cortex volumes","volume":"218","author":"Harms","year":"2013","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.schres.2013.12.015_bb0100","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s00213-003-1761-y","article-title":"The hippocampus in schizophrenia: a review of the neuropathological evidence and its pathophysiological implications","volume":"174","author":"Harrison","year":"2004","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.schres.2013.12.015_bb0105","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1002\/hipo.1067","article-title":"Neuropathological studies of synaptic connectivity in the hippocampal formation in schizophrenia","volume":"11","author":"Harrison","year":"2001","journal-title":"Hippocampus"},{"key":"10.1016\/j.schres.2013.12.015_bb0110","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1176\/appi.ajp.162.10.1888","article-title":"Treatment of cognitive impairment in early psychosis: a comparison of risperidone and haloperidol in a large long-term trial","volume":"162","author":"Harvey","year":"2005","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2013.12.015_bb0120","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1002\/hipo.1068","article-title":"Neuroimaging studies of the hippocampus in schizophrenia","volume":"11","author":"Heckers","year":"2001","journal-title":"Hippocampus"},{"key":"10.1016\/j.schres.2013.12.015_bb0125","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/71152","article-title":"Distinct representations of eye gaze and identity in the distributed human neural system for face perception","volume":"3","author":"Hoffman","year":"2000","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.schres.2013.12.015_bb0130","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1176\/appi.ajp.162.12.2233","article-title":"Regional deficits in brain volume in schizophrenia: a meta-analysis of voxel-based morphometry studies","volume":"162","author":"Honea","year":"2005","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2013.12.015_bb0135","doi-asserted-by":"crossref","first-page":"4138","DOI":"10.1002\/hbm.20835","article-title":"Functional and anatomical connectivity abnormalities in left inferior frontal gyrus in schizophrenia","volume":"30","author":"Jeong","year":"2009","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.schres.2013.12.015_bb0140","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1006\/nimg.2002.1180","article-title":"Structural gray matter differences between first-episode schizophrenics and normal controls using voxel-based morphometry","volume":"17","author":"Job","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.schres.2013.12.015_bb0145","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.schres.2012.03.015","article-title":"Medial temporal lobe structure and cognition in individuals with schizophrenia and in their non-psychotic siblings","volume":"138","author":"Karnik-Henry","year":"2012","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.schres.2013.12.015_bb0150","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/schbul\/13.2.261","article-title":"The positive and negative syndrome scale (PANSS) for schizophrenia","volume":"13","author":"Kay","year":"1987","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.schres.2013.12.015_bb0155","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.biopsych.2005.01.003","article-title":"Defining a cognitive function decrement in schizophrenia","volume":"57","author":"Keefe","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.schres.2013.12.015_bb0160","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1006\/nimg.2002.1296","article-title":"Voxel-based morphometric analysis of gray matter in first episode schizophrenia","volume":"17","author":"Kubicki","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.schres.2013.12.015_bb0165","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1176\/ajp.2006.163.12.2103","article-title":"Middle and inferior temporal gyrus gray matter volume abnormalities in first-episode schizophrenia: an MRI study","volume":"163","author":"Kuroki","year":"2006","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2013.12.015_bb0170","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/npp.2010.156","article-title":"Cognitive control deficits in schizophrenia: mechanisms and meaning","volume":"36","author":"Lesh","year":"2011","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.schres.2013.12.015_bb0175","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1093\/schbul\/sbn190","article-title":"Facial emotion processing in schizophrenia: a meta-analysis of functional neuroimaging data","volume":"36","author":"Li","year":"2010","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.schres.2013.12.015_bb0180","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.schres.2009.06.020","article-title":"Cognitive performance is related to cortical grey matter volumes in early stages of schizophrenia: a population-based study of first-episode psychosis","volume":"113","author":"Minatogawa-Chang","year":"2009","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.schres.2013.12.015_bb0185","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1017\/S0033291709992297","article-title":"A systematic review of the effects of antipsychotic drugs on brain volume","volume":"40","author":"Moncrieff","year":"2010","journal-title":"Psychol. Med."},{"key":"10.1016\/j.schres.2013.12.015_bb0190","doi-asserted-by":"crossref","first-page":"3215","DOI":"10.1093\/brain\/awt116","article-title":"A family affair: brain abnormalities in siblings of patients with schizophrenia","volume":"136","author":"Moran","year":"2013","journal-title":"Brain"},{"key":"10.1016\/j.schres.2013.12.015_bb0195","doi-asserted-by":"crossref","first-page":"s111","DOI":"10.1192\/bjp.191.51.s111","article-title":"Grey matter abnormalities in first-episode schizophrenia and affective psychosis","volume":"51","author":"Morgan","year":"2007","journal-title":"Br. J. Psychiatry Suppl."},{"key":"10.1016\/j.schres.2013.12.015_bb0200","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1097\/YCO.0b013e328324f895","article-title":"Emotional face processing in schizophrenia","volume":"22","author":"Morris","year":"2009","journal-title":"Curr. Opin. Psychiatry"},{"key":"10.1016\/j.schres.2013.12.015_bb0205","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1093\/brain\/awm265","article-title":"Orbitofrontal volume deficit in schizophrenia and thought disorder","volume":"131","author":"Nakamura","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.schres.2013.12.015_bb0210","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1017\/S0033291709005315","article-title":"Do antipsychotic drugs affect brain structure? A systematic and critical review of MRI findings","volume":"39","author":"Navari","year":"2009","journal-title":"Psychol. Med."},{"key":"10.1016\/j.schres.2013.12.015_bb0215","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1176\/appi.ajp.161.9.1603","article-title":"Middle and inferior temporal gyrus gray matter volume abnormalities in chronic schizophrenia: an MRI study","volume":"161","author":"Onitsuka","year":"2004","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2013.12.015_bb0220","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1006\/nimg.2000.0662","article-title":"The effect of medial frontal and posterior parietal demyelinating lesions on Stroop interference","volume":"13","author":"Pujol","year":"2001","journal-title":"Neuroimage"},{"key":"10.1016\/j.schres.2013.12.015_bb0225","series-title":"The Halstead-Reitan Neuropsychological Test Battery: Theory and Clinical Interpretation","author":"Reitan","year":"1997"},{"key":"10.1016\/j.schres.2013.12.015_bb0230","doi-asserted-by":"crossref","first-page":"s117","DOI":"10.1192\/bjp.191.51.s117","article-title":"Grey matter abnormalities in Brazilians with first-episode psychosis","volume":"51","author":"Schaufelberger","year":"2007","journal-title":"Br. J. Psychiatry Suppl."},{"key":"10.1016\/j.schres.2013.12.015_bb0235","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1176\/appi.ajp.2010.09081187","article-title":"The hippocampal formation in schizophrenia","volume":"167","author":"Tamminga","year":"2010","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2013.12.015_bb0240","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.biopsych.2004.06.026","article-title":"The relationship between volumetric brain changes and cognitive function: a family study on schizophrenia","volume":"56","author":"Toulopoulou","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.schres.2013.12.015_bb0245","series-title":"WMS-R: Wechsler Memory Scale\u2014Revised: Manual","author":"Wechsler","year":"1987"},{"key":"10.1016\/j.schres.2013.12.015_bb0250","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.pscychresns.2012.04.014","article-title":"Prefrontal gray matter morphology mediates the association between serum anticholinergicity and cognitive functioning in early course schizophrenia","volume":"204","author":"Wojtalik","year":"2012","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.schres.2013.12.015_bb0255","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.bbr.2013.05.030","article-title":"The hippocampus supports high-resolution binding in the service of perception, working memory and long-term memory","volume":"254","author":"Yonelinas","year":"2013","journal-title":"Behav. Brain Res."}],"container-title":["Schizophrenia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996413006932?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996413006932?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,7]],"date-time":"2018-10-07T05:28:39Z","timestamp":1538890119000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920996413006932"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2]]},"references-count":51,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["S0920996413006932"],"URL":"https:\/\/doi.org\/10.1016\/j.schres.2013.12.015","relation":{},"ISSN":["0920-9964"],"issn-type":[{"value":"0920-9964","type":"print"}],"subject":[],"published":{"date-parts":[[2014,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hippocampal and orbital inferior frontal gray matter volume abnormalities and cognitive deficit in treatment-naive, first-episode patients with schizophrenia","name":"articletitle","label":"Article Title"},{"value":"Schizophrenia Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.schres.2013.12.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}