{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T09:24:47Z","timestamp":1790846687977,"version":"4.1.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"1-3","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002341","name":"Academy of Finland","doi-asserted-by":"publisher","award":["132071, 268336"],"award-info":[{"award-number":["132071, 268336"]}],"id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010125","name":"Jalmari and Rauha Ahokas Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100010125","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100006306","name":"Sigrid Jus\u00e9lius Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100006306","id-type":"DOI","asserted-by":"crossref"}]},{"name":"NARSAD: Brain and Behavior Research Fund"},{"DOI":"10.13039\/501100000265","name":"UK Medical Research Council","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100011935","name":"Northern Finland Health Care Support Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100011935","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Oy H. Lundbeck Foundation"}],"content-domain":{"domain":["clinicalkey.jp","schres-journal.com","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Schizophrenia Research"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.schres.2014.06.035","type":"journal-article","created":{"date-parts":[[2014,7,15]],"date-time":"2014-07-15T09:30:21Z","timestamp":1405416621000},"page":"134-141","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":80,"title":["Lifetime use of antipsychotic medication and its relation to change of verbal learning and memory in midlife schizophrenia \u2014 An observational 9-year follow-up study"],"prefix":"10.1016","volume":"158","author":[{"given":"Anja P.","family":"Husa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina","family":"Rannikko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jani","family":"Moilanen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Haapea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham K.","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Barnett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter B.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3692-8228","authenticated-orcid":false,"given":"Matti","family":"Isohanni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannu","family":"Koponen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jouko","family":"Miettunen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"J\u00e4\u00e4skel\u00e4inen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.schres.2014.06.035_bb0005","first-page":"428","article-title":"Antipsychotic drug effects in schizophrenia: a review of longitudinal fMRI investigations and neural interpretations","volume":"20","author":"Abbott","year":"2013","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.schres.2014.06.035_bb0010","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1007\/s00406-006-0667-1","article-title":"Neurocognitive functioning in patients with first-episode schizophrenia: results of a prospective 5-year follow-up study","volume":"256","author":"Albus","year":"2006","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.schres.2014.06.035_bb0015","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.biopsych.2011.05.017","article-title":"Progressive brain change in schizophrenia: a prospective longitudinal study of first-episode schizophrenia","volume":"70","author":"Andreasen","year":"2011","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.schres.2014.06.035_bb0020","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1176\/appi.ajp.2013.12050674","article-title":"Relapse duration, treatment intensity, and brain tissue loss in schizophrenia: a prospective longitudinal MRI study","volume":"170","author":"Andreasen","year":"2013","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2014.06.035_bb0025","series-title":"Psychotropic Drug Directory 2003\/2004: The Professional's Pocket Handbook and Aide Memoire","author":"Bazire","year":"2004"},{"key":"10.1016\/j.schres.2014.06.035_bb0030","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1023\/A:1023870821631","article-title":"Verbal declarative memory dysfunction in schizophrenia: from clinical assessment to genetics and brain mechanisms","volume":"13","author":"Cirillo","year":"2003","journal-title":"Neuropsychol. Rev."},{"key":"10.1016\/j.schres.2014.06.035_bb0035","series-title":"California Verbal Learning Test","author":"Delis","year":"1987"},{"key":"10.1016\/j.schres.2014.06.035_bb0040","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00228-013-1600-y","article-title":"Long-term neurocognitive effects of antipsychotics in schizophrenia: a network meta-analysis","volume":"70","author":"D\u00e9sam\u00e9ricq","year":"2014","journal-title":"Eur. J. Clin. Pharmacol."},{"key":"10.1016\/j.schres.2014.06.035_bb0045","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1177\/0269881108100777","article-title":"Cognitive effects of antipsychotic dosage and polypharmacy: a study with the BACS in patients with schizophrenia and schizoaffective disorder","volume":"24","author":"Elie","year":"2010","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.schres.2014.06.035_bb0050","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1016\/j.neubiorev.2013.06.001","article-title":"Progressive brain changes in schizophrenia related to antipsychotic treatment? A meta-analysis of longitudinal MRI studies","volume":"37","author":"Fusar-Poli","year":"2013","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.schres.2014.06.035_bb0055","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1038\/npp.2009.211","article-title":"Circumstances under which practice does not make perfect: a review of the practice effect literature in schizophrenia and its relevance to clinical treatment studies","volume":"35","author":"Goldberg","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.schres.2014.06.035_bb0060","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/S0006-3223(02)01370-7","article-title":"The neurocognitive effects of low-dose haloperidol: a two-year comparison with risperidone","volume":"51","author":"Green","year":"2002","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.schres.2014.06.035_bb0065","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1001\/archpsyc.55.2.145","article-title":"A follow-up magnetic resonance imaging study of schizophrenia. Relationship of neuroanatomical changes to clinical and neurobehavioral measures","volume":"55","author":"Gur","year":"1998","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.schres.2014.06.035_bb0070","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s00127-007-0178-z","article-title":"Non-participation may bias the results of a psychiatric survey: an analysis from the survey including magnetic resonance imaging within the Northern Finland 1966 Birth Cohort","volume":"42","author":"Haapea","year":"2007","journal-title":"Soc. Psychiatry Psychiatr. Epidemiol."},{"key":"10.1016\/j.schres.2014.06.035_bb0075","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1146\/annurev.clinpsy.2.022305.095206","article-title":"Cognition and aging in psychopathology: focus on schizophrenia and depression","volume":"2","author":"Harvey","year":"2006","journal-title":"Annu. Rev. Clin. Psychol."},{"key":"10.1016\/j.schres.2014.06.035_bb0080","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1001\/archgenpsychiatry.2010.199","article-title":"Long-term antipsychotic treatment and brain volumes. A longitudinal study of first-episode schizophrenia","volume":"68","author":"Ho","year":"2011","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.schres.2014.06.035_bb0085","series-title":"IBM SPSS Statistics for Windows, Version 21.0","author":"IBM Corp.","year":"2012"},{"issue":"6","key":"10.1016\/j.schres.2014.06.035_bb0090","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1093\/schbul\/sbq057","article-title":"Neuropsychological performance in older patients with schizophrenia: a meta-analysis of cross-sectional and longitudinal studies","volume":"37","author":"Irani","year":"2011","journal-title":"Schizophr. Bull."},{"issue":"6","key":"10.1016\/j.schres.2014.06.035_bb0095","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1176\/appi.ajp.161.6.985","article-title":"Comparative effect of atypical and conventional antipsychotic drugs on neurocognition in first-episode psychosis: a randomized, double-blind trial of olanzapine versus low doses of haloperidol","volume":"161","author":"Keefe","year":"2004","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2014.06.035_bb0105","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.biopsych.2005.06.022","article-title":"Long-term neurocognitive effects of olanzapine or low-dose haloperidol in first-episode psychosis","volume":"59","author":"Keefe","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.schres.2014.06.035_bb0110","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1001\/archpsyc.64.6.633","article-title":"Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE trial","volume":"64","author":"Keefe","year":"2007","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.schres.2014.06.035_bb0115","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1471-244X-9-24","article-title":"Treatment of schizophrenia with antipsychotics in Norwegian emergency wards, a cross-sectional national study","volume":"9","author":"Kroken","year":"2009","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.schres.2014.06.035_bb0120","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1037\/a0014708","article-title":"Neurocognition in first-episode schizophrenia: a meta-analytic review","volume":"23","author":"Mesholam-Gately","year":"2009","journal-title":"Neuropsychology"},{"key":"10.1016\/j.schres.2014.06.035_bb0125","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1080\/13803395.2012.668875","article-title":"Verbal learning and memory and their associations with brain morphology and illness course in schizophrenia spectrum psychoses","volume":"34","author":"Rannikko","year":"2012","journal-title":"J. Clin. Exp. Neuropsychol."},{"key":"10.1016\/j.schres.2014.06.035_bb0130","first-page":"1","article-title":"Groups at risk in low birth weight infants and perinatal mortality","volume":"193","author":"Rantakallio","year":"1969","journal-title":"Acta Paediatr. Scand. Suppl."},{"issue":"2","key":"10.1016\/j.schres.2014.06.035_bb0135","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1176\/appi.ajp.2009.09040574","article-title":"Static and dynamic cognitive deficits in childhood preceding adult schizophrenia: a 30-year study","volume":"167","author":"Reichenberg","year":"2010","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2014.06.035_bb0140","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1471-244X-10-47","article-title":"The switch from conventional to atypical antipsychotic treatment should not be based exclusively on the presence of cognitive deficits. A pilot study in individuals with schizophrenia","volume":"10","author":"Selva-Vera","year":"2010","journal-title":"BMC Psychiatry"},{"issue":"4","key":"10.1016\/j.schres.2014.06.035_bb0145","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1016\/j.neubiorev.2011.12.015","article-title":"Systematic meta-review and quality assessment of the structural brain alterations in schizophrenia","volume":"36","author":"Shepherd","year":"2012","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.schres.2014.06.035_bb0150","series-title":"Structured Clinical Interview for DSM-III-R -Patient Edition (SCID-P, 9\/1\/89 Version) New York","author":"Spitzer","year":"1989"},{"issue":"3","key":"10.1016\/j.schres.2014.06.035_bb0155","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1124\/jpet.106.106047","article-title":"Time-dependent cognitive deficits associated with first and second generation antipsychotics: cholinergic dysregulation as a potential mechanism","volume":"320","author":"Terry","year":"2007","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.schres.2014.06.035_bb0160","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1097\/NMD.0b013e31824cb359","article-title":"Cognitive impairments in schizophrenia and schizoaffective disorder: relationship with clinical characteristics","volume":"200","author":"Torniainen","year":"2012","journal-title":"J. Nerv. Ment. Dis."},{"key":"10.1016\/j.schres.2014.06.035_bb0165","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1586\/14737175.4.1.43","article-title":"Verbal memory deficit in patients with schizophrenia: an important future target for treatment","volume":"4","author":"Toulopoulou","year":"2004","journal-title":"Expert. Rev. Neurother."},{"key":"10.1016\/j.schres.2014.06.035_bb0170","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s00406-010-0186-y","article-title":"Cognitive functioning in severe psychiatric disorders: a general population study","volume":"261","author":"Tuulio-Henriksson","year":"2011","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.schres.2014.06.035_bb9000","series-title":"Longitudinal changes in total brain volume in schizophrenia: relation to symptom severity, cognition and antipsychotic medication","author":"Veijola","year":"2014"},{"key":"10.1016\/j.schres.2014.06.035_bb0175","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1017\/S0033291700036527","article-title":"Cognitive dysfunction in schizophrenia followed up over 5years, and its longitudinal relationship to the emergence of tardive dyskinesia","volume":"20","author":"Waddington","year":"1990","journal-title":"Psychol. Med."},{"key":"10.1016\/j.schres.2014.06.035_bb0180","series-title":"Textbook in Psychiatric Epidemiology","first-page":"155","article-title":"The pharmacoepidemiology of psychiatric medications","author":"Wang","year":"2011"},{"issue":"12","key":"10.1016\/j.schres.2014.06.035_bb0185","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.1212\/01.WNL.0000036905.59156.A1","article-title":"Cognitive activity and incident AD in a population-based sample of older persons","volume":"59","author":"Wilson","year":"2002","journal-title":"Neurology"}],"container-title":["Schizophrenia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996414003272?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996414003272?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,12]],"date-time":"2020-05-12T02:24:47Z","timestamp":1589250287000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920996414003272"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":37,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S0920996414003272"],"URL":"https:\/\/doi.org\/10.1016\/j.schres.2014.06.035","relation":{},"ISSN":["0920-9964"],"issn-type":[{"value":"0920-9964","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lifetime use of antipsychotic medication and its relation to change of verbal learning and memory in midlife schizophrenia \u2014 An observational 9-year follow-up study","name":"articletitle","label":"Article Title"},{"value":"Schizophrenia Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.schres.2014.06.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}