{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T02:17:08Z","timestamp":1789611428192,"version":"build-2803163510"},"reference-count":79,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Schizophrenia Research"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.schres.2020.11.050","type":"journal-article","created":{"date-parts":[[2021,1,13]],"date-time":"2021-01-13T17:33:42Z","timestamp":1610559222000},"page":"180-187","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Longitudinal investigation of the relationship between omega-3 polyunsaturated fatty acids and neuropsychological functioning in recent-onset psychosis: A randomized clinical trial"],"prefix":"10.1016","volume":"228","author":[{"given":"Philip R.","family":"Szeszko","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert K.","family":"McNamara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan A.","family":"Gallego","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil K.","family":"Malhotra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usha","family":"Govindarajulu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart D.","family":"Peters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delbert G.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.schres.2020.11.050_bb0005","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jnutbio.2018.03.019","article-title":"Whole blood n-3 fatty acids are associated with executive function in 2\u20136-year-old Northern Ghanaian children","volume":"57","author":"Adjepong","year":"2018","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.schres.2020.11.050_bb0010","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.schres.2019.06.020","article-title":"Comparison of erythrocyte omega-3 index, fatty acids and molecular phospholipid species in people at ultra-high risk of developing psychosis and healthy people","volume":"226","author":"Alqarni","year":"2020","journal-title":"Schizophr Res."},{"issue":"2","key":"10.1016\/j.schres.2020.11.050_bb0015","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1001\/archgenpsychiatry.2009.192","article-title":"Long-chain \u03c9-3 fatty acids for indicated prevention of psychotic disorders: a randomized, placebo-controlled trial","volume":"67","author":"Amminger","year":"2010","journal-title":"Arch. Gen. Psychiatry"},{"issue":"3","key":"10.1016\/j.schres.2020.11.050_bb0020","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.biopsych.2019.08.030","article-title":"The NEURAPRO biomarker analysis: long-chain Omega-3 fatty acids improve 6-month and 12-month outcomes in youths at ultra-high risk for psychosis","volume":"87","author":"Amminger","year":"2020","journal-title":"Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.schres.2020.11.050_bb0025","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/S0006-3223(02)01443-9","article-title":"Essential polyunsaturated fatty acid and lipid peroxide levels in never-medicated and medicated schizophrenia patients","volume":"53","author":"Arvindakshan","year":"2003","journal-title":"Biol. Psychiatry"},{"issue":"sup1","key":"10.1016\/j.schres.2020.11.050_bb0030","first-page":"1281916","article-title":"Dietary polyunsaturated fatty acids, brain function and mental health","volume":"28","author":"Bentsen","year":"2017","journal-title":"Microb. Ecol. Health Dis."},{"key":"10.1016\/j.schres.2020.11.050_bb0035","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.plefa.2017.10.002","article-title":"Neurocognitive effects of an omega-3 fatty acid and vitamins E+ C in schizophrenia: a randomised controlled trial","volume":"136","author":"Bentsen","year":"2018","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.schres.2020.11.050_bb0040","doi-asserted-by":"crossref","first-page":"393","DOI":"10.3389\/fpsyt.2019.00393","article-title":"Relationship between polyunsaturated fatty acids and psychopathology in the NEURAPRO clinical trial","volume":"10","author":"Berger","year":"2019","journal-title":"Front. Psychiatry"},{"issue":"1","key":"10.1016\/j.schres.2020.11.050_bb0045","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.biopsych.2013.06.007","article-title":"Adolescent behavior and dopamine availability are uniquely sensitive to dietary omega-3 fatty acid deficiency","volume":"75","author":"Bondi","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.schres.2020.11.050_bb0050","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.schres.2018.09.022","article-title":"Metabolic abnormalities and low dietary Omega 3 are associated with symptom severity and worse functioning prior to the onset of psychosis: findings from the North American Prodrome Longitudinal Studies Consortium","volume":"204","author":"Cadenhead","year":"2019","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.schres.2020.11.050_bb0055","doi-asserted-by":"crossref","first-page":"7458","DOI":"10.1038\/srep07458","article-title":"n-3 PUFA supplementation benefits microglial responses to myelin pathology","volume":"4","author":"Chen","year":"2014","journal-title":"Sci. Rep."},{"issue":"1\u20133","key":"10.1016\/j.schres.2020.11.050_bb0060","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.schres.2007.11.012","article-title":"Deficit of theory of mind in individuals at ultra-high-risk for schizophrenia","volume":"99","author":"Chung","year":"2008","journal-title":"Schizophr. Res."},{"issue":"9","key":"10.1016\/j.schres.2020.11.050_bb0065","doi-asserted-by":"crossref","first-page":"2176","DOI":"10.3945\/jn.115.214650","article-title":"Maternal fish oil supplementation affects the social behavior, brain fatty acid profile, and sickness response of piglets","volume":"145","author":"Clouard","year":"2015","journal-title":"J. Nutr."},{"key":"10.1016\/j.schres.2020.11.050_bb0070","first-page":"298","article-title":"Cognition, dopamine and bioactive lipids in schizophrenia","volume":"3","author":"Condray","year":"2011","journal-title":"Front. Biosci. (Scholar Edit.)"},{"key":"10.1016\/j.schres.2020.11.050_bb0075","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.schres.2018.02.018","article-title":"What does the managing emotions branch of the MSCEIT add to the MATRICS consensus cognitive battery?","volume":"197","author":"DeTore","year":"2018","journal-title":"Schizophr. Res."},{"issue":"4","key":"10.1016\/j.schres.2020.11.050_bb0080","doi-asserted-by":"crossref","first-page":"e0121945","DOI":"10.1371\/journal.pone.0121945","article-title":"cocor: a comprehensive solution for the statistical comparison of correlations","volume":"10","author":"Diedenhofen","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.schres.2020.11.050_bb0085","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.biochi.2019.01.022","article-title":"The n-3 docosapentaenoic acid (DPA): a new player in the n-3 long chain polyunsaturated fatty acid family","volume":"159","author":"Drouin","year":"2019","journal-title":"Biochimie"},{"key":"10.1016\/j.schres.2020.11.050_bb0090","doi-asserted-by":"crossref","first-page":"52","DOI":"10.3389\/fnagi.2015.00052","article-title":"Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA","volume":"7","author":"Dyall","year":"2015","journal-title":"Front. Aging Neurosci."},{"issue":"1","key":"10.1016\/j.schres.2020.11.050_bb0095","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.euroneuro.2018.11.1106","article-title":"Chronic dietary changes in n-6\/n-3 polyunsaturated fatty acid ratios cause developmental delay and reduce social interest in mice","volume":"29","author":"van Elst","year":"2019","journal-title":"Eur. Neuropsychopharmacol."},{"issue":"9","key":"10.1016\/j.schres.2020.11.050_bb0100","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1176\/appi.ajp.159.9.1596","article-title":"Randomized, placebo-controlled study of ethyl-eicosapentaenoic acid as supplemental treatment in schizophrenia","volume":"159","author":"Emsley","year":"2002","journal-title":"Am. J. Psychiatr."},{"issue":"1","key":"10.1016\/j.schres.2020.11.050_bb0105","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.schres.2006.03.023","article-title":"The effects of eicosapentaenoic acid in tardive dyskinesia: a randomized, placebo-controlled trial","volume":"84","author":"Emsley","year":"2006","journal-title":"Schizophr. Res."},{"issue":"5\u20136","key":"10.1016\/j.schres.2020.11.050_bb0110","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.plefa.2007.10.013","article-title":"An n-3 fatty acid deficient diet affects mouse spatial learning in the Barnes circular maze","volume":"77","author":"Fedorova","year":"2007","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"issue":"12","key":"10.1016\/j.schres.2020.11.050_bb0115","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1176\/appi.ajp.158.12.2071","article-title":"A placebo-controlled trial of omega-3 fatty acid (ethyl eicosapentaenoic acid) supplementation for residual symptoms and cognitive impairment in schizophrenia","volume":"158","author":"Fenton","year":"2001","journal-title":"Am. J. Psychiatr."},{"key":"10.1016\/j.schres.2020.11.050_bb0120","series-title":"Structured Clinical Interview for Axis I DSM-IV Disorders","author":"First","year":"1994"},{"key":"10.1016\/j.schres.2020.11.050_bb0125","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.nut.2016.10.019","article-title":"Effects of \u03c9-3 fatty acids on stereotypical behavior and social interactions in Wistar rats prenatally exposed to lipopolysaccarides","volume":"35","author":"Fortunato","year":"2017","journal-title":"Nutrition"},{"issue":"3","key":"10.1016\/j.schres.2020.11.050_bb0130","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.clinbiochem.2009.08.016","article-title":"Biological variability of blood omega-3 biomarkers","volume":"43","author":"Harris","year":"2010","journal-title":"Clin Biochem."},{"issue":"1\u20132","key":"10.1016\/j.schres.2020.11.050_bb0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.psychres.2012.09.041","article-title":"Red blood cell polyunsaturated fatty acids measured in red blood cells and schizophrenia: a meta-analysis","volume":"207","author":"Hoen","year":"2013","journal-title":"Psychiatry Res."},{"issue":"7","key":"10.1016\/j.schres.2020.11.050_bb0140","doi-asserted-by":"crossref","first-page":"103","DOI":"10.5539\/gjhs.v6n7p103","article-title":"Randomized, placebo-controlled clinical trial of omega-3 as supplemental treatment in schizophrenia","volume":"6","author":"Jamilian","year":"2014","journal-title":"Global J. Health Sci."},{"key":"10.1016\/j.schres.2020.11.050_bb0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.plipres.2013.10.002","article-title":"Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: the influence of LCPUFA on neural development, aging, and neurodegeneration","volume":"53","author":"Janssen","year":"2014","journal-title":"Prog. Lipid Res."},{"issue":"2\u20133","key":"10.1016\/j.schres.2020.11.050_bb0150","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.schres.2012.08.014","article-title":"A meta-analysis of the polyunsaturated fatty acid composition of erythrocyte membranes in schizophrenia","volume":"141","author":"van der Kemp","year":"2012","journal-title":"Schizophr. Res."},{"issue":"2","key":"10.1016\/j.schres.2020.11.050_bb0155","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1176\/appi.ajp.2007.07010043","article-title":"The MATRICS consensus cognitive battery, part 2: co-norming and standardization","volume":"165","author":"Kern","year":"2008","journal-title":"Am. J. Psychiatr."},{"issue":"1\u20133","key":"10.1016\/j.schres.2020.11.050_bb0160","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.schres.2014.06.032","article-title":"Relationship between membrane fatty acids and cognitive symptoms and information processing in individuals at ultra-high risk for psychosis","volume":"158","author":"Kim","year":"2014","journal-title":"Schizophr. Res."},{"issue":"3","key":"10.1016\/j.schres.2020.11.050_bb0165","article-title":"Relationship between erythrocyte fatty acid composition and psychopathology in the Vienna omega-3 study","volume":"11","author":"Kim","year":"2016","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.schres.2020.11.050_bb0170","doi-asserted-by":"crossref","first-page":"663","DOI":"10.2174\/1570159X13666150630173047","article-title":"Omega 3 fatty acids: novel neurotherapeutic targets for cognitive dysfunction in mood disorders and schizophrenia?","volume":"13","author":"Knochel","year":"2015","journal-title":"Curr. Neuropharmacol."},{"issue":"9","key":"10.1016\/j.schres.2020.11.050_bb0175","doi-asserted-by":"crossref","first-page":"e641","DOI":"10.1038\/tp.2015.126","article-title":"Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model","volume":"5","author":"Li","year":"2015","journal-title":"Transl. Psychiatry"},{"issue":"2","key":"10.1016\/j.schres.2020.11.050_bb0180","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1194\/jlr.M055590","article-title":"Chronic dietary n-6 PUFA deprivation leads to conservation of arachidonic acid and more rapid loss of DHA in rat brain phospholipids","volume":"56","author":"Lin","year":"2015","journal-title":"J. Lipid Res."},{"issue":"5","key":"10.1016\/j.schres.2020.11.050_bb0185","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.jpsychores.2013.07.012","article-title":"Anger induced by interferon-alpha is moderated by ratio of arachidonic acid to omega-3 fatty acids","volume":"75","author":"Lotrich","year":"2013","journal-title":"J. Psychosom. Res."},{"issue":"3\u20134","key":"10.1016\/j.schres.2020.11.050_bb0190","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.plefa.2011.05.004","article-title":"The relation between the omega-3 index and arachidonic acid is bell shaped: synergistic at low EPA+ DHA status and antagonistic at high EPA+ DHA status","volume":"85","author":"Luxwolda","year":"2011","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.schres.2020.11.050_bb0195","doi-asserted-by":"crossref","first-page":"111219","DOI":"10.1016\/j.pscychresns.2020.111219","article-title":"A 16-week randomized placebo- controlled trial investigating the effects of omega-3 polyunsaturated fatty acid treatment on white matter microstructure in recent-onset psychosis patients concurrently treated with risperidone","volume":"307","author":"Lyall","year":"2020","journal-title":"Psychiatry Res. Neuroimaging"},{"issue":"9","key":"10.1016\/j.schres.2020.11.050_bb0200","doi-asserted-by":"crossref","first-page":"e1229","DOI":"10.1038\/tp.2017.182","article-title":"Polyunsaturated fatty acid deficiency during neurodevelopment in mice models the prodromal state of schizophrenia through epigenetic changes in nuclear receptor genes","volume":"7","author":"Maekawa","year":"2017","journal-title":"Transl. Psychiatry"},{"issue":"4","key":"10.1016\/j.schres.2020.11.050_bb0205","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.clindermatol.2010.03.020","article-title":"Healing fats of the skin: the structural and immunologic roles of the \u03c9-6 and \u03c9-3 fatty acids","volume":"28","author":"McCusker","year":"2010","journal-title":"Clin. Dermatol."},{"issue":"1","key":"10.1016\/j.schres.2020.11.050_bb0210","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1001\/jamapsychiatry.2016.2902","article-title":"Effect of \u03c9-3 polyunsaturated fatty acids in young people at ultrahigh risk for psychotic disorders: the NEURAPRO randomized clinical trial","volume":"74","author":"McGorry","year":"2017","journal-title":"JAMA Psychiatry"},{"issue":"1\u20132","key":"10.1016\/j.schres.2020.11.050_bb0220","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.jad.2010.03.015","article-title":"Selective deficits in erythrocyte docosahexaenoic acid composition in adult patients with bipolar disorder and major depressive disorder","volume":"126","author":"McNamara","year":"2010","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.schres.2020.11.050_bb0225","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.pscychresns.2017.10.003","article-title":"Glutamate homeostasis in the adult rat prefrontal cortex is altered by cortical docosahexaenoic acid accrual during adolescence: an in vivo 1H MRS study","volume":"270","author":"McNamara","year":"2017","journal-title":"Psychiatry Res. Neuroimaging"},{"key":"10.1016\/j.schres.2020.11.050_bb4010","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/796462","article-title":"Adult medication-free schizophrenic patients exhibit long-chain omega-3 Fatty Acid deficiency: implications for cardiovascular disease risk","author":"McNamara","year":"2013","journal-title":"Cardiovasc. Psychiatry Neurol."},{"issue":"2","key":"10.1016\/j.schres.2020.11.050_bb0230","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1093\/schbul\/sbv133","article-title":"Levels of red blood cell fatty acids in patients with psychosis, their unaffected siblings, and healthy controls","volume":"42","author":"Medema","year":"2016","journal-title":"Schizophr. Bull."},{"issue":"1","key":"10.1016\/j.schres.2020.11.050_bb0235","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1037\/0033-2909.111.1.172","article-title":"Comparing correlated correlation coefficients","volume":"111","author":"Meng","year":"1992","journal-title":"Psychol. Bull."},{"issue":"3","key":"10.1016\/j.schres.2020.11.050_bb0240","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1021\/ac60235a044","article-title":"Rapid preparation of fatty acid esters from lipids for gas chromatographic analysis","volume":"38","author":"Metcalfe","year":"1966","journal-title":"Anal. Chem."},{"issue":"6","key":"10.1016\/j.schres.2020.11.050_bb0245","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0066697","article-title":"Low blood long chain omega-3 fatty acids in UK children are associated with poor cognitive performance and behavior: a cross-sectional analysis from the DOLAB study","volume":"8","author":"Montgomery","year":"2013","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.schres.2020.11.050_bb0250","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1080\/00325481.2019.1607414","article-title":"The eicosapentaenoic acid: arachidonic acid ratio and its clinical utility in cardiovascular disease","volume":"131","author":"Nelson","year":"2019","journal-title":"Postgrad. Med."},{"key":"10.1016\/j.schres.2020.11.050_bb0255","series-title":"MCCB\u2013MATRICS Consensus Cognitive Battery\u2013Manual. Matrics Assessment Inc. MATRICS Assessment Battery With Permission of Barbara Cornblatt","author":"Nuechterlein","year":"2006"},{"issue":"1","key":"10.1016\/j.schres.2020.11.050_bb0260","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0028-3932(71)90067-4","article-title":"The assessment and analysis of handedness: the Edinburgh inventory","volume":"9","author":"Oldfield","year":"1971","journal-title":"Neuropsychologia"},{"issue":"4","key":"10.1016\/j.schres.2020.11.050_bb0265","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1080\/09168451.2017.1403888","article-title":"Effects of eicosapentaenoic acid and docosahexaenoic acid on anxiety-like behavior in socially isolated rats","volume":"82","author":"Oshima","year":"2018","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.schres.2020.11.050_bb0270","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jpsychires.2015.11.013","article-title":"A randomized controlled study of the efficacy of six-month supplementation with concentrated fish oil rich in omega-3 polyunsaturated fatty acids in first episode schizophrenia","volume":"73","author":"Pawe\u0142czyk","year":"2016","journal-title":"J. Psychiatr. Res."},{"issue":"6","key":"10.1016\/j.schres.2020.11.050_bb0275","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1111\/eip.12267","article-title":"Differences in omega-3 and omega-6 polyunsaturated fatty acid consumption in people at ultra-high risk of psychosis, first-episode schizophrenia, and in healthy controls","volume":"11","author":"Pawe\u0142czyk","year":"2017","journal-title":"Early Intervent. Psychiatry"},{"issue":"1","key":"10.1016\/j.schres.2020.11.050_bb0280","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0022-3956(01)00048-6","article-title":"Study Group E-EM. A dose-ranging exploratory study of the effects of ethyl-eicosapentaenoate in patients with persistent schizophrenic symptoms","volume":"36","author":"Peet","year":"2002","journal-title":"J. Psychiatr. Res."},{"issue":"3","key":"10.1016\/j.schres.2020.11.050_bb0285","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0920-9964(00)00083-9","article-title":"Two double-blind placebo-controlled pilot studies of eicosapentaenoic acid in the treatment of schizophrenia","volume":"49","author":"Peet","year":"2001","journal-title":"Schizophr. Res."},{"issue":"1","key":"10.1016\/j.schres.2020.11.050_bb0290","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.plefa.2009.04.007","article-title":"Polyunsaturated fatty acids and brain white matter anisotropy in recent-onset schizophrenia: a preliminary study","volume":"81","author":"Peters","year":"2009","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"issue":"4","key":"10.1016\/j.schres.2020.11.050_bb0295","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1093\/schbul\/sbs089","article-title":"Polyunsaturated fatty acid concentration predicts myelin integrity in early-phase psychosis","volume":"39","author":"Peters","year":"2013","journal-title":"Schizophr. Bull."},{"issue":"2","key":"10.1016\/j.schres.2020.11.050_bb0300","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1093\/schbul\/sbv056","article-title":"Social cognition psychometric evaluation: results of the initial psychometric study","volume":"42","author":"Pinkham","year":"2016","journal-title":"Schizophr. Bull."},{"issue":"15","key":"10.1016\/j.schres.2020.11.050_bb0305","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1017\/S0033291718001794","article-title":"Cognition, psychosis risk and metabolic measures in two adolescent birth cohorts","volume":"48","author":"Ramsay","year":"2018","journal-title":"Psychol. Med."},{"issue":"1","key":"10.1016\/j.schres.2020.11.050_bb0310","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.plefa.2012.05.003","article-title":"Translational studies on regulation of brain docosahexaenoic acid (DHA) metabolism in vivo","volume":"88","author":"Rapoport","year":"2013","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.schres.2020.11.050_bb0315","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.comppsych.2018.07.016","article-title":"Predictors of residency status in chronically institutionalized and community dwelling schizophrenia patients","volume":"86","author":"Reynolds","year":"2018","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.schres.2020.11.050_bb0325","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.schres.2018.09.006","article-title":"A potential role for adjunctive omega-3 polyunsaturated fatty acids for depression and anxiety symptoms in recent onset psychosis: results from a 16\u00a0week randomized placebo-controlled trial for participants concurrently treated with risperidone","volume":"204","author":"Robinson","year":"2019","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.schres.2020.11.050_bb0330","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.scog.2017.05.001","article-title":"Omega-3 fatty acids related to cognitive impairment in patients with schizophrenia","volume":"9","author":"Satogami","year":"2017","journal-title":"Schizophrenia Res. Cognit."},{"issue":"3","key":"10.1016\/j.schres.2020.11.050_bb0335","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.plefa.2010.07.001","article-title":"Polyunsaturated fatty acids deficits are associated with psychotic state and negative symptoms in patients with schizophrenia","volume":"83","author":"Sethom","year":"2010","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"issue":"3","key":"10.1016\/j.schres.2020.11.050_bb0340","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF02859265","article-title":"Essential fatty acids, DHA and human brain","volume":"72","author":"Singh","year":"2005","journal-title":"Indian J. Pediatrics"},{"issue":"6","key":"10.1016\/j.schres.2020.11.050_bb0345","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.plefa.2003.08.008","article-title":"From membrane phospholipid defects to altered neurotransmission: is arachidonic acid a nexus in the pathophysiology of schizophrenia?","volume":"69","author":"Skosnik","year":"2003","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"issue":"5","key":"10.1016\/j.schres.2020.11.050_bb0350","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.3945\/ajcn.112.053371","article-title":"DHA supplementation improved both memory and reaction time in healthy young adults: a randomized controlled trial","volume":"97","author":"Stonehouse","year":"2013","journal-title":"Am. Clin. Nutr."},{"key":"10.1016\/j.schres.2020.11.050_bb0355","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.physbeh.2013.05.002","article-title":"Concomitant docosahexaenoic acid administration ameliorates stress-induced cognitive impairment in rats","volume":"118","author":"Trofimiuk","year":"2013","journal-title":"Physiol. Behav."},{"issue":"2\u20133","key":"10.1016\/j.schres.2020.11.050_bb0360","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0165-1781(00)00228-6","article-title":"Symptom dimensions in recent-onset schizophrenia and mania: a principal components analysis of the 24-item Brief Psychiatric Rating Scale","volume":"97","author":"Ventura","year":"2000","journal-title":"Psychiatry Res."},{"issue":"1\u20132","key":"10.1016\/j.schres.2020.11.050_bb0365","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.psychres.2010.02.016","article-title":"Hostility of drug-free patients with schizophrenia and n\u22123 polyunsaturated fatty acid levels in red blood cells","volume":"177","author":"Watari","year":"2010","journal-title":"Psychiatry Res."},{"issue":"11","key":"10.1016\/j.schres.2020.11.050_bb0370","doi-asserted-by":"crossref","first-page":"3059","DOI":"10.1093\/cercor\/bht163","article-title":"Long-chain omega-3 fatty acids improve brain function and structure in older adults","volume":"24","author":"Witte","year":"2014","journal-title":"Cereb. Cortex"},{"issue":"1","key":"10.1016\/j.schres.2020.11.050_bb0375","first-page":"112","article-title":"Anchoring the BPRS: an aid to improved reliability","volume":"24","author":"Woerner","year":"1988","journal-title":"Psychopharmacol. Bull."},{"key":"10.1016\/j.schres.2020.11.050_bb0380","doi-asserted-by":"crossref","DOI":"10.1100\/tsw.2002.870","article-title":"Membrane pathology in schizophrenia: implication for arachidonic acid signaling","volume":"2","author":"Yao","year":"2002","journal-title":"TheScientificWorldJOURNAL"},{"issue":"7","key":"10.1016\/j.schres.2020.11.050_bb0385","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3390\/nu8070385","article-title":"The erythrocyte fatty acid profile and cognitive function in old Chinese adults","volume":"8","author":"Yuan","year":"2016","journal-title":"Nutrients"},{"issue":"3","key":"10.1016\/j.schres.2020.11.050_bb0390","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0120391","article-title":"Docosahexaenoic acid and adult memory: a systematic review and meta-analysis","volume":"10","author":"Yurko-Mauro","year":"2015","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.schres.2020.11.050_bb0395","doi-asserted-by":"crossref","first-page":"372","DOI":"10.14336\/AD.2017.0501","article-title":"Predictors of memory in healthy aging: polyunsaturated fatty acid balance and fornix white matter integrity","volume":"8","author":"Zamroziewicz","year":"2017","journal-title":"Aging Dis."},{"issue":"4","key":"10.1016\/j.schres.2020.11.050_bb0400","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1093\/ajcn\/75.4.662","article-title":"The dopamine mesocorticolimbic pathway is affected by deficiency in n\u22123 polyunsaturated fatty acids","volume":"75","author":"Zimmer","year":"2002","journal-title":"Am. J. Clin. Nutr."}],"container-title":["Schizophrenia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996420306290?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996420306290?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:41:16Z","timestamp":1760298076000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920996420306290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":79,"alternative-id":["S0920996420306290"],"URL":"https:\/\/doi.org\/10.1016\/j.schres.2020.11.050","relation":{},"ISSN":["0920-9964"],"issn-type":[{"value":"0920-9964","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Longitudinal investigation of the relationship between omega-3 polyunsaturated fatty acids and neuropsychological functioning in recent-onset psychosis: A randomized clinical trial","name":"articletitle","label":"Article Title"},{"value":"Schizophrenia Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.schres.2020.11.050","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}