{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:48:57Z","timestamp":1773967737916,"version":"3.50.1"},"reference-count":12,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Schizophrenia Research"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.schres.2022.10.022","type":"journal-article","created":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T18:17:08Z","timestamp":1667931428000},"page":"62-66","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Higher central set point of thyroid homeostasis in drug-na\u00efve patients affected by first episode schizophrenia"],"prefix":"10.1016","volume":"250","author":[{"given":"Desheng","family":"Zhai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jialuo","family":"Bing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuchang","family":"Shan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hu","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy","family":"Wen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Songyin","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaijun","family":"Niu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taizhen","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongbin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravi","family":"Retnakaran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Hao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruiling","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shi Wu","family":"Wen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.schres.2022.10.022_bb0005","unstructured":"SPINA, n.d.SPINA (n.d.) Thyr, software for structure parameter inference approach of thyroid function., http:\/\/spina.medical-cybernetics.de."},{"key":"10.1016\/j.schres.2022.10.022_bb0010","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3389\/fendo.2017.00163","article-title":"Thyroid allostasis-adaptive responses of thyrotropic feedback control to conditions of strain, stress, and developmental programming","volume":"8","author":"Chatzitomaris","year":"2017","journal-title":"Front. Endocrinol."},{"issue":"2","key":"10.1016\/j.schres.2022.10.022_bb0015","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1176\/appi.ajp.2011.11040631","article-title":"Abnormal thyroid function tests in psychiatric patients: a red herring?","volume":"169","author":"Dickerman","year":"2012","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2022.10.022_bb0020","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3389\/fendo.2016.00057","article-title":"Calculated parameters of thyroid homeostasis: emerging tools for differential diagnosis and clinical research","volume":"7","author":"Dietrich","year":"2016","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.schres.2022.10.022_bb0025","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.schres.2019.01.030","article-title":"Stress during critical periods of development and risk for schizophrenia","volume":"213","author":"Gomes","year":"2019","journal-title":"Schizophr. Res."},{"issue":"4","key":"10.1016\/j.schres.2022.10.022_bb0030","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1111\/j.1365-2265.2009.03534.x","article-title":"The use of thyroid function tests in the diagnosis of hypopituitarism: definition and evaluation of the TSH index","volume":"71","author":"Jostel","year":"2009","journal-title":"Clin. Endocrinol."},{"issue":"2","key":"10.1016\/j.schres.2022.10.022_bb0035","doi-asserted-by":"crossref","first-page":"303","DOI":"10.2337\/dc18-1410","article-title":"Impaired sensitivity to thyroid hormones is associated with diabetes and metabolic syndrome","volume":"42","author":"Laclaustra","year":"2019","journal-title":"Diabetes Care"},{"issue":"20","key":"10.1016\/j.schres.2022.10.022_bb0040","first-page":"1582","article-title":"Influence of gender, age and season on thyroid hormone reference interval","volume":"98","author":"Qiu","year":"2018","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"10.1016\/j.schres.2022.10.022_bb0045","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/569147","article-title":"Revisiting thyroid hormones in schizophrenia","volume":"2012","author":"Santos","year":"2012","journal-title":"J. Thyroid. Res."},{"issue":"1","key":"10.1016\/j.schres.2022.10.022_bb0050","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/bcp.14949","article-title":"Mirtazapine use may increase the risk of hypothyroxinaemia in patients affected by major depressive disorder","volume":"88","author":"Zhao","year":"2022","journal-title":"Br. J. Clin. Pharmacol."},{"issue":"12","key":"10.1016\/j.schres.2022.10.022_bb0055","doi-asserted-by":"crossref","first-page":"4823","DOI":"10.1111\/bcp.14928","article-title":"Dose-responses association of acute phase quetiapine treatment with risk of new onset hypothyroidism in schizophrenia patients","volume":"87","author":"Zhao","year":"2021","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.schres.2022.10.022_bb0060","series-title":"Chinese National Guidelines of Diagnosis and Treatment for Schizophrenia","author":"Zhao","year":"2015"}],"container-title":["Schizophrenia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996422004054?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996422004054?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:48:50Z","timestamp":1760298530000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920996422004054"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":12,"alternative-id":["S0920996422004054"],"URL":"https:\/\/doi.org\/10.1016\/j.schres.2022.10.022","relation":{},"ISSN":["0920-9964"],"issn-type":[{"value":"0920-9964","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Higher central set point of thyroid homeostasis in drug-na\u00efve patients affected by first episode schizophrenia","name":"articletitle","label":"Article Title"},{"value":"Schizophrenia Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.schres.2022.10.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}